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Volumn 25, Issue 1, 2003, Pages 59-72

Assessing accuracy in linkage analysis by means of confidence regions

Author keywords

Confidence region; Linkage analysis; Locus estimation; Perfect marker information; Slope to noise ratio

Indexed keywords

ACCURACY; ARTICLE; GENE LOCUS; GENETIC MODEL; HUMAN; LINKAGE ANALYSIS; PEDIGREE; PHENOTYPE; PROBABILITY; QUANTITATIVE GENETICS;

EID: 0037772428     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/gepi.10248     Document Type: Article
Times cited : (12)

References (30)
  • 1
    • 0036178196 scopus 로고    scopus 로고
    • Bias in estimates of quantitative-trait-locus effect in genome scan: Demonstration of the phenomenon and a method-of-moments procedure for reducings bias
    • Allison DB, Fernandez JR, Heo M, Zhu S, Etzel C, Beasly TM, Amos C. 2002. Bias in estimates of quantitative-trait-locus effect in genome scan: Demonstration of the phenomenon and a method-of-moments procedure for reducings bias. Am J Hum Genet 70:575-85.
    • (2002) Am J Hum Genet , vol.70 , pp. 575-585
    • Allison, D.B.1    Fernandez, J.R.2    Heo, M.3    Zhu, S.4    Etzel, C.5    Beasly, T.M.6    Amos, C.7
  • 2
    • 0022728801 scopus 로고
    • Effects of misspecifying genetic parameters in lod score analysis
    • Clerget-Darpoux F, Bonaïti-Pellié C, Hochez J. 1986. Effects of misspecifying genetic parameters in lod score analysis. Biometrics 42:393-9.
    • (1986) Biometrics , vol.42 , pp. 393-399
    • Clerget-Darpoux, F.1    Bonaïti-Pellié, C.2    Hochez, J.3
  • 3
    • 0030973207 scopus 로고    scopus 로고
    • A simple method to calculate resolving power and confidence interval of QTL map location
    • Darvasi A, Soller M. 1997. A simple method to calculate resolving power and confidence interval of QTL map location. Behav Genet 27:125-32.
    • (1997) Behav Genet , vol.27 , pp. 125-132
    • Darvasi, A.1    Soller, M.2
  • 4
    • 0027278088 scopus 로고
    • Detecting marker-QTL linkage and estimating QTL gene effect and map position using a saturated genetic map
    • Darvasi A, Weinreb A, Minke V, Weller JI, Soller M. 1993. Detecting marker-QTL linkage and estimating QTL gene effect and map position using a saturated genetic map. Genetics 134:943-51.
    • (1993) Genetics , vol.134 , pp. 943-951
    • Darvasi, A.1    Weinreb, A.2    Minke, V.3    Weller, J.I.4    Soller, M.5
  • 5
    • 0032944437 scopus 로고    scopus 로고
    • Statistical methods for mapping quantitative trait loci from a dense set of markers
    • Dupuis J, Siegmund D. 1999. Statistical methods for mapping quantitative trait loci from a dense set of markers. Genetics 151:373-86.
    • (1999) Genetics , vol.151 , pp. 373-386
    • Dupuis, J.1    Siegmund, D.2
  • 6
    • 0027487931 scopus 로고
    • Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent
    • Feingold E, Brown PO, Siegmund D. 1993. Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. Am J Hum Genet 53:234-51.
    • (1993) Am J Hum Genet , vol.53 , pp. 234-251
    • Feingold, E.1    Brown, P.O.2    Siegmund, D.3
  • 7
    • 0033814570 scopus 로고    scopus 로고
    • Comparison of allele-sharing statistics for general pedigrees
    • Feingold E, Song KK, Weeks DE. 2000. Comparison of allele-sharing statistics for general pedigrees. Genet Epidemiol [Suppl] 19:92-8.
    • (2000) Genet Epidemiol [Suppl] , vol.19 , pp. 92-98
    • Feingold, E.1    Song, K.K.2    Weeks, D.E.3
  • 8
    • 0035209177 scopus 로고    scopus 로고
    • Large upward bias in estimation of locus-specific effects from genomewide scans
    • Göring H, Terwilliger J, Blangero J. 2001. Large upward bias in estimation of locus-specific effects from genomewide scans. Am J Hum Genet 69:1357-69.
    • (2001) Am J Hum Genet , vol.69 , pp. 1357-1369
    • Göring, H.1    Terwilliger, J.2    Blangero, J.3
  • 9
    • 4244114381 scopus 로고    scopus 로고
    • Asymptotic estimation theory of multipoint linkage analysis under perfect marker information
    • Preprint 2001:16, Centre for Mathematical Sciences, Lund University, Sweden. (in press)
    • Hössjer O. 2001a. Preprint 2001:16, Centre for Mathematical Sciences, Lund University, Sweden. Asymptotic estimation theory of multipoint linkage analysis under perfect marker information. Ann Stat. (in press).
    • (2001) Ann Stat
    • Hössjer, O.1
  • 10
    • 4243618834 scopus 로고    scopus 로고
    • Determining inheritance distributions via stochastic penetrances
    • Preprint 2001:17, Centre for Mathematical Sciences, Lund University, Sweden. (in press)
    • Hössjer O. 2001b. Preprint 2001:17, Centre for Mathematical Sciences, Lund University, Sweden. Determining inheritance distributions via stochastic penetrances. J Am Stat Assoc. (in press).
    • (2001) J Am Stat Assoc
    • Hössjer, O.1
  • 12
    • 0028019067 scopus 로고
    • Asymptotic theory for gene mapping
    • Kong A, Wright F. 1994. Asymptotic theory for gene mapping. Proc Natl Acad Sci USA 91:9705-9.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9705-9709
    • Kong, A.1    Wright, F.2
  • 13
    • 0030861903 scopus 로고    scopus 로고
    • The use of a genetic map of biallelic markers in linkage studies
    • Kruglyak L. 1997. The use of a genetic map of biallelic markers in linkage studies. Nat Genet 17:21-4.
    • (1997) Nat Genet , vol.17 , pp. 21-24
    • Kruglyak, L.1
  • 14
    • 85058248980 scopus 로고    scopus 로고
    • Linkage thresholds for two-stage genome scans
    • Kruglyak L, Daly MJ. 1998. Linkage thresholds for two-stage genome scans. Am J Hum Genet 62:994-6.
    • (1998) Am J Hum Genet , vol.62 , pp. 994-996
    • Kruglyak, L.1    Daly, M.J.2
  • 15
    • 0028952250 scopus 로고
    • High-resolution gene mapping of complex traits
    • Kruglyak L, Lander ES. 1995. High-resolution gene mapping of complex traits. Am J Hum Genet 56:1212-23.
    • (1995) Am J Hum Genet , vol.56 , pp. 1212-1223
    • Kruglyak, L.1    Lander, E.S.2
  • 16
    • 0029886532 scopus 로고    scopus 로고
    • Parametric and nonparametric linkage analysis: A unified multipoint approach
    • Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES. 1996. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 58:1347-63.
    • (1996) Am J Hum Genet , vol.58 , pp. 1347-1363
    • Kruglyak, L.1    Daly, M.J.2    Reeve-Daly, M.P.3    Lander, E.S.4
  • 17
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander EL, Kryglyak L. 1995. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-7.
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.L.1    Kryglyak, L.2
  • 18
    • 0035205458 scopus 로고    scopus 로고
    • A robust identity-by-descent procedure using affected sib pairs: Multipoint mapping for complex diseases
    • Liang KY, Chiu Y-F, Beaty TH. 2001. A robust identity-by-descent procedure using affected sib pairs: multipoint mapping for complex diseases. Hum Hered 51:64-78.
    • (2001) Hum Hered , vol.51 , pp. 64-78
    • Liang, K.Y.1    Chiu, Y.-F.2    Beaty, T.H.3
  • 19
    • 0032969483 scopus 로고    scopus 로고
    • Optimal allele-sharing statistics for genetic mapping using affected relatives
    • McPeek MS. 1999. Optimal allele-sharing statistics for genetic mapping using affected relatives. Genet Epidemiol 16:225-49.
    • (1999) Genet Epidemiol , vol.16 , pp. 225-249
    • McPeek, M.S.1
  • 20
    • 0037554290 scopus 로고    scopus 로고
    • Licentiate thesis, Chalmers University of Technology, Gothenburg, Sweden
    • Nilsson S. 1999. Two contributions to genetic linkage analysis. Licentiate thesis, Chalmers University of Technology, Gothenburg, Sweden.
    • (1999) Two Contributions to Genetic Linkage Analysis
    • Nilsson, S.1
  • 22
    • 0025019555 scopus 로고
    • Linkage strategies for genetically complex traits. I. Multilocus models
    • Risch N. 1990. Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 46:222-8.
    • (1990) Am J Hum Genet , vol.46 , pp. 222-228
    • Risch, N.1
  • 23
    • 0034972488 scopus 로고    scopus 로고
    • A survey of affected-sibship statistics for nonparametric linkage analysis
    • Sengul H, Weeks DE, Feingold E. 2001. A survey of affected-sibship statistics for nonparametric linkage analysis. Am J Hum Genet 69:179-90.
    • (2001) Am J Hum Genet , vol.69 , pp. 179-190
    • Sengul, H.1    Weeks, D.E.2    Feingold, E.3
  • 24
    • 0001758770 scopus 로고
    • Boundary crossing probabilities and statistical applications
    • Siegmund D. 1986. Boundary crossing probabilities and statistical applications. Ann Stat 14:361-404.
    • (1986) Ann Stat , vol.14 , pp. 361-404
    • Siegmund, D.1
  • 25
    • 0036844237 scopus 로고    scopus 로고
    • Upward bias in estimation of genetic effects
    • Siegmund D. 2002. Upward bias in estimation of genetic effects. Am J Hum Genet 71:1183-8.
    • (2002) Am J Hum Genet , vol.71 , pp. 1183-1188
    • Siegmund, D.1
  • 26
    • 0026746111 scopus 로고
    • On the relative importance of marker heterozygosity and intermarker distance in gene mapping
    • Terwillinger JD, Ding Y, Ott J. 1992. On the relative importance of marker heterozygosity and intermarker distance in gene mapping. Genomics 13:951-6.
    • (1992) Genomics , vol.13 , pp. 951-956
    • Terwillinger, J.D.1    Ding, Y.2    Ott, J.3
  • 27
    • 0023894935 scopus 로고
    • The affected-pedigree-member method of linkage analysis
    • Weeks DE, Lange K. 1988. The affected-pedigree-member method of linkage analysis. Am J Hum Genet 42:315-326.
    • (1988) Am J Hum Genet , vol.42 , pp. 315-326
    • Weeks, D.E.1    Lange, K.2
  • 28
    • 0026510552 scopus 로고
    • A multilocus extension of the affected-pedigree-member method of linkage analysis
    • Weeks DE, Lange K. 1992. A multilocus extension of the affected-pedigree-member method of linkage analysis. Am J Hum Genet 50:859-68.
    • (1992) Am J Hum Genet , vol.50 , pp. 859-868
    • Weeks, D.E.1    Lange, K.2
  • 29
    • 0038189170 scopus 로고    scopus 로고
    • Genome scanning for linkage: An overview
    • Whittemore AS. 1996. Genome scanning for linkage: an overview. Biometrics 50:118-27.
    • (1996) Biometrics , vol.50 , pp. 118-127
    • Whittemore, A.S.1
  • 30
    • 0028301661 scopus 로고
    • A class of tests for linkage using affected pedigree members
    • Whittemore AS, Halpern J. 1994. A class of tests for linkage using affected pedigree members. Biometrics 50:118-27.
    • (1994) Biometrics , vol.50 , pp. 118-127
    • Whittemore, A.S.1    Halpern, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.