Mutational analysis of the enzymatic domain of Clostridium difficile toxin B reveals novel inhibitors of the wild-type toxin

Infection and Immunity

Volumn 71, Issue 6, 2003, Pages 3294-3301

  Spyres, Lea M ^a   Daniel, Jeremy ^a   Hensley, Amy ^a   Qa'Dan, Maen ^a   Ortiz Leduc, William ^a   Ballard, Jimmy D ^a  

^a UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOXIN; ANTHRAX TOXIN; CLOSTRIDIUM DIFFICILE TOXIN B; CLOSTRIDIUM TOXIN; ENZYME; ENZYME INHIBITOR; GLUCOSYLTRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROLASE; LETHAL TOXIN; PROTEIN CDC42; RAC PROTEIN; RHO FACTOR; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANTIGEN BINDING; ARTICLE; CELL PROTECTION; CELLULAR DISTRIBUTION; CHO CELL; CLOSTRIDIUM; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM NOVYI; CLOSTRIDIUM SORDELLII; CONTROLLED STUDY; CYTOTOXICITY; DELETION MUTANT; ENZYME ACTIVITY; FUSION GENE; GLYCOSYLATION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; TOXIN STRUCTURE;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CHO CELLS; CRICETINAE; GLYCOSYLATION; HELA CELLS; HUMANS; MUTATION; VIRULENCE FACTORS;

EID: 0037767234     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.6.3294-3301.2003     Document Type: Article

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