Anticlastogenic effect of aqueous extracts of Agaricus blazei on CHO-k1 cells, studying different developmental phases of the mushroom

Toxicology in Vitro

Volumn 17, Issue 4, 2003, Pages 465-469

  Bellini, M F ^a   Giacomini, N L ^a   Eira, A F ^b   Ribeiro, L R ^c   Mantovani, M S ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

Author keywords

Agaricus blazei; Anticlastogenicity; Cell culture; CHO k1 cells; Chromosome aberration; Mushroom

Indexed keywords

AGARICUS BLAZEI EXTRACT; MESYLIC ACID; PLANT EXTRACT; UNCLASSIFIED DRUG;

AGARICUS BLAZEI; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL COUNT; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CHO CELL; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DNA STRAND BREAKAGE; HIGH TEMPERATURE; LOW TEMPERATURE; MUSHROOM; NONHUMAN; ROOM TEMPERATURE; SPECIES COMPARISON; SPOROGENESIS;

AGARICUS BLAZEI; BASIDIOMYCOTA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0037756678     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(03)00043-2     Document Type: Article

References (21)

1. Bez G.C., Jordão B.Q., Vicentini V.E.P., Mantovani M.S. Differential Protection of A and B chlorophyll in MMC- mediated induction of chromatid and isochromatid breaks in human lymphocytes culture. Cytologia. 66:2001;313-318.
2. Brusick D.J. Cytogenetics assays. aberrations and SCE techniques Douglas J.F. Carcinogenesis and Mutagenesis Testing. 1984;265-278 Human Press, New Jersey.
3. Chang H.L., Chao G.R., Chen C.C., Mau J.L. Non-volatile taste components of Agaricus blazei, Antrodia camphorata and Cordyceps militaris mycelia. Food Chemistry. 74:2001;203-207.
4. Chang R. Functional properties of edible mushrooms. Nutrition Reviews. 54:1996;91-93.
5. Delmanto R.D., De Lima P.L.A., Suguia M.M., Salvadori D.M.F., Da Eira A.F., Speit G., Ribeiro L.R. Antimutagenic effect of Agaricus blazei Murrill mushroom on the genotoxicity induced by cyclophosphamide. Mutation Res. 496:2001;15-21.
6. Kawagishi H., Katsumi R., Sazama T., Mizuno T., Hagiwara T., Nakamura T. Cytotoxic steroids from the mushroom Agaricus blazei. Phytochemistry. 27:1988;51-58.
7. Lohman P.H.M., Gentile J.M., Gentile G., Ferguson L.R. Antimutagenesis/anticarcinogenesis 2001. screening, methods and biomarkers Mutation Res. 496:2001;1-4.
8. Menoli R.C.N., Mantovani M.S., Ribeiro L.R., Speit G., Jordão B.Q. Antimutagenic effects of the mushroom Agaricus blazei Murrill extracts on V79 cells. Mutation Res. 496:2001;5-13.
9. Mizuno T.K. Bioactive biomolecules of mushrooms - food, function and medicinal effect of mushroom fungi. Food Reviews International. 11:1995;7-21.
10. Mizuno T.K. Agaricus blazei Murill. Medicinal and Dietary Effects Food Reviews International. 11:1995;167-172.
11. Mizushina Y., Hanashima L., Yamaguchi T., Takemura M., Sugawara F., Saneyoshi M., Matsukage A., Yoshida S., Sakaguchi K. A mushroom fruiting body-inducing substance inhibits activities of replicate DNA polymerases. Biochemical and Biophysical Research Communications. 249:1998;17-22.
12. Ohno N., Furukawa M., Miura N.N., Adachi Y., Motoi M., Yadomae T. Antitumor beta-glucan from the cultured fruit body of Agaricus blazei. Biological and Pharmaceutical Bulletin. 24:2001;820-828.
13. Oliveira J.M., Jordão B.Q., Ribeiro L.R., Eira A.F., Mantovani M.S. Anti-genotoxic effect of aqueous extracts of sun mushroom (Agaricus blazei Murill lineage 99/26) in mammalian cells in vitro. Food and Chemical Toxicology. 40:2002;15-20.
14. Osaki Y., Kato T., Yamamoto K., Okubo J., Miyazaki T. Antimutagenic and bactericidal substances in the fruit body of a basidiomycete Agaricus-blazei. Yakugaku Zasshi. 114:1994;342-350.
15. Sorimachi K., Akimoto K., Ikehara Y., Inafuku K., Okubo A., Yamazaki S. Secretion of TNF- alpha, IL-8 and nitric oxide by macrophages activated with Agaricus blazei Murrill fractions in vitro. Cell Struture and Function. 26:2001;103-108.
16. Sorimachi K., Ikehara Y., Maezato G., Okubo A., Yamazaki S., Akimoto K., Niwa A. Inhibition by Agaricus blazei fractions of cytopathic effect induced by western equine encephalitis (Wee) virus on Vero cells in vitro. Bioscience Biotechnology and Biochesmitry. 65:2001;1645-1647.
17. Takaku T., Kimura Y., Okuda H. Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action. Journal of Nutrition. 131:2001;1409-1413.
18. Takeda Y., Togashi H., Shinzawa H., Miyano S., Ishii R., Karasawa T., Takeda Y., Saito T., Saito K., Haga H., Matsuo T., Aoki M., Mitsuhashi H., Watanabe H., Takahashi T. Spontaneous regression of hepatocellular carcinoma and review of literature. Journal of Gastroenterology and Hepatology. 15:2000;1079-1086.
19. Takusaburo E., Yoshiaki F. Antitumor effect of peptide-glucan preparation extracted from Agaricus blazei in a double-grafted tumor system in mice. Biotherapy Dordrecht. 11:1998;259-265.
20. Togashi H., Mizushima Y., Takemura M., Sugawara F., Koshino H., Esumi Y., Uzama J., Kumagai H., Matsukage A., Yoshida S., Sakaguchi K. 4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro. Biochemical Pharmacology. 56:1998;583-590.
21. Waters M.D., Brady A.L., Stack H.F., Brockman H.E. Antimutagenicity profiles for some model compounds. Mutation Research. 238:1990;57-85.