Methods of estimation of IC50 and SC50 parameters for indirect response models from single dose data

Journal of Pharmaceutical Sciences

Volumn 92, Issue 7, 2003, Pages 1438-1454

  Wyska, Elzbieta ^a   Mager, Donald E ^a   Krzyzanski, Wojciech ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

IC50; Indirect response models; Parameter estimation; SC50

Indexed keywords

ACCURACY; ARTICLE; DRUG CONCENTRATION; DRUG ELIMINATION; IC 50; MATHEMATICAL MODEL; PHARMACODYNAMICS; SC 50; SINGLE DRUG DOSE; STEADY STATE; DOSE RESPONSE; STATISTICS; THEORETICAL MODEL;

DOSE-RESPONSE RELATIONSHIP, DRUG; INHIBITORY CONCENTRATION 50; MODELS, THEORETICAL; STATISTICS;

EID: 0037745100     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10407     Document Type: Article

References (10)

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