메뉴 건너뛰기




Volumn 80, Issue 1, 2003, Pages 63-79

Combined uridine and choline administration improves cognitive deficits in spontaneously hypertensive rats

Author keywords

5 Choice serial reaction time (5 CSRT); Choline; Delayed non matching to position (DNMTP); Memory; Morris water maze; Open field; Rats; Selective attention; Spatial learning; Spontaneously hypertensive rats (SHR); Uridine; Uridine 5 monophosphate 2Na (UMP)

Indexed keywords

C 7527; CHOLINE; URIDINE PHOSPHATE;

EID: 0037739814     PISSN: 10747427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7427(03)00024-8     Document Type: Article
Times cited : (85)

References (88)
  • 1
    • 0020371462 scopus 로고
    • New strategies in the management of Parkinson's disease: A biological approach using a phospholipid precursor (CDP-choline)
    • Agnoli A., Ruggieri S.et al. New strategies in the management of Parkinson's disease: A biological approach using a phospholipid precursor (CDP-choline). Neuropsychobiology. 8:1982;289-296.
    • (1982) Neuropsychobiology , vol.8 , pp. 289-296
    • Agnoli, A.1    Ruggieri, S.2
  • 2
    • 0026408621 scopus 로고
    • Age-related changes in memory and their pharmacologic modulation
    • Agut J., Ortiz J.A. Age-related changes in memory and their pharmacologic modulation. Annales of New York Academy Sciences. 640:1991;295-297.
    • (1991) Annales of New York Academy Sciences , vol.640 , pp. 295-297
    • Agut, J.1    Ortiz, J.A.2
  • 3
    • 0021706826 scopus 로고
    • ′ ) diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine
    • ′ ) diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine Neuropharmacology. 23:1984;1403-1406.
    • (1984) Neuropharmacology , vol.23 , pp. 1403-1406
    • Agut, J.1    Coviella, I.L.2
  • 4
    • 0027451394 scopus 로고
    • ′ -diphosphate choline administration to rats increases brain phospholipid levels
    • ′ -diphosphate choline administration to rats increases brain phospholipid levels Annales of New York Academy Sciences. 695:1993;318-320.
    • (1993) Annales of New York Academy Sciences , vol.695 , pp. 318-320
    • Agut, J.1    Lopez, I.2    Coviella, G.3
  • 5
    • 0034353149 scopus 로고    scopus 로고
    • ′ )diphosphocholine modulates dopamine K(+)-evoked release in striatum measured by microdialysis
    • ′ )diphosphocholine modulates dopamine K(+)-evoked release in striatum measured by microdialysis Annales of New York Academy Sciences. 920:2000;332-335.
    • (2000) Annales of New York Academy Sciences , vol.920 , pp. 332-335
    • Agut, J.1    Ortiz, J.A.2
  • 7
    • 0033403796 scopus 로고    scopus 로고
    • Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion
    • Alvarez X., Mouzo A.R.et al. Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion. Methods Find Experimental and Clinical Pharmacology. 21:1999;633-644.
    • (1999) Methods Find Experimental and Clinical Pharmacology , vol.21 , pp. 633-644
    • Alvarez, X.1    Mouzo, A.R.2
  • 8
    • 0032698068 scopus 로고    scopus 로고
    • Citicoline protects hippocampal neurons against apoptosis induced by brain β-amyloid deposits plus cerebral hypofusion in rats
    • Alvarez X.A., Sampedro C., Lozano R., Cacabelos R. Citicoline protects hippocampal neurons against apoptosis induced by brain β-amyloid deposits plus cerebral hypofusion in rats. Methods Find Experimental and Clinical Pharmacology. 21:1999;535-540.
    • (1999) Methods Find Experimental and Clinical Pharmacology , vol.21 , pp. 535-540
    • Alvarez, X.A.1    Sampedro, C.2    Lozano, R.3    Cacabelos, R.4
  • 9
    • 0037760779 scopus 로고    scopus 로고
    • Strain differences in diurnal pattern of locomotor activity and the response to methylphenidate
    • Amini, B., Yang, P., Swann, A. C., & Dafny, N. (2001). Strain differences in diurnal pattern of locomotor activity and the response to methylphenidate. Society of Neuroscicence Abstracts. 960.5.
    • (2001) Society of Neuroscicence Abstracts , pp. 9605
    • Amini, B.1    Yang, P.2    Swann, A.C.3    Dafny, N.4
  • 10
    • 0034113888 scopus 로고    scopus 로고
    • Education, activity, health, blood pressure and apolipoprotein E as predictors of cognitive change in old age: A review
    • Anstey K., Christensen H. Education, activity, health, blood pressure and apolipoprotein E as predictors of cognitive change in old age: A review. Gerontology. 46:2000;163-177.
    • (2000) Gerontology , vol.46 , pp. 163-177
    • Anstey, K.1    Christensen, H.2
  • 11
    • 0030479855 scopus 로고    scopus 로고
    • Citicoline for treatment of experimental focal ischemia: Histologic and behavioral outcome
    • Aronowski J., Strong R., Grotta J.C. Citicoline for treatment of experimental focal ischemia: Histologic and behavioral outcome. Neurological Research. 18:1996;570-574.
    • (1996) Neurological Research , vol.18 , pp. 570-574
    • Aronowski, J.1    Strong, R.2    Grotta, J.C.3
  • 12
    • 0032127161 scopus 로고    scopus 로고
    • Sex differences in operant discrimination behavior in an animal model of attention-deficit hyperactivity disorder
    • Berger D.F., Sagvolden T. Sex differences in operant discrimination behavior in an animal model of attention-deficit hyperactivity disorder. Behavioral Brain Research. 94:1998;73-82.
    • (1998) Behavioral Brain Research , vol.94 , pp. 73-82
    • Berger, D.F.1    Sagvolden, T.2
  • 13
  • 15
    • 0032126164 scopus 로고    scopus 로고
    • Chronic L-deprenyl treatment alters brain monoamine levels and reduces impulsiveness in an animal model of attention-deficit/hyperactivity disorder
    • Boix F., Qiao S.W., Kolpus T., Sagvolden T. Chronic L-deprenyl treatment alters brain monoamine levels and reduces impulsiveness in an animal model of attention-deficit/hyperactivity disorder. Behavioral Brain Research. 94:1998;153-162.
    • (1998) Behavioral Brain Research , vol.94 , pp. 153-162
    • Boix, F.1    Qiao, S.W.2    Kolpus, T.3    Sagvolden, T.4
  • 17
    • 0028216445 scopus 로고
    • Effects of local application of dopaminergic drugs into the dorsal part of the medial prefrontal cortex of rats in a delayed matching to position task: Comparison with local cholinergic blockade
    • Broersen L.M., Heinsbroek R.P., de Bruin J.P., Joosten R.N., van Hest A., Olivier B. Effects of local application of dopaminergic drugs into the dorsal part of the medial prefrontal cortex of rats in a delayed matching to position task: Comparison with local cholinergic blockade. Brain Research. 645:1994;113-122.
    • (1994) Brain Research , vol.645 , pp. 113-122
    • Broersen, L.M.1    Heinsbroek, R.P.2    De Bruin, J.P.3    Joosten, R.N.4    Van Hest, A.5    Olivier, B.6
  • 18
    • 0028966868 scopus 로고
    • The role of the medial prefrontal cortex of rats in short-term memory functioning: Further support for involvement of cholinergic, rather than dopaminergic mechanisms
    • Broersen L.M., Heinsbroek R.P., de Bruin J.P., Uylings H.B., Olivier B. The role of the medial prefrontal cortex of rats in short-term memory functioning: Further support for involvement of cholinergic, rather than dopaminergic mechanisms. Brain Research. 674:1995;221-229.
    • (1995) Brain Research , vol.674 , pp. 221-229
    • Broersen, L.M.1    Heinsbroek, R.P.2    De Bruin, J.P.3    Uylings, H.B.4    Olivier, B.5
  • 19
    • 0033951841 scopus 로고    scopus 로고
    • Evaluation of the spontaneously hypertensive rat as a model of attention deficit hyperactivity disorder: Acquisition and performance of the DRL-60s test
    • Bull E., Reavill C., Hagan J.J., Overend P., Jones D.N. Evaluation of the spontaneously hypertensive rat as a model of attention deficit hyperactivity disorder: Acquisition and performance of the DRL-60s test. Behavioral Brain Research. 109:2000;27-35.
    • (2000) Behavioral Brain Research , vol.109 , pp. 27-35
    • Bull, E.1    Reavill, C.2    Hagan, J.J.3    Overend, P.4    Jones, D.N.5
  • 20
    • 0028351522 scopus 로고
    • Effects of CDP-choline on cognition and cerebral hemodynamics in patients with Alzheimer's disease
    • Caamano J., Gomez M.J.et al. Effects of CDP-choline on cognition and cerebral hemodynamics in patients with Alzheimer's disease. Methods Find Exp. Clin. Pharmacol. 16:1994;211-218.
    • (1994) Methods Find Exp. Clin. Pharmacol , vol.16 , pp. 211-218
    • Caamano, J.1    Gomez, M.J.2
  • 22
    • 0026610983 scopus 로고
    • Serotonin-2 receptor agonists and serotonergic anorectic drugs affect rats' performance differently in a five-choice serial reaction time task
    • Carli M., Samanin R. Serotonin-2 receptor agonists and serotonergic anorectic drugs affect rats' performance differently in a five-choice serial reaction time task. Psychopharmacology. 106:1992;228-234.
    • (1992) Psychopharmacology , vol.106 , pp. 228-234
    • Carli, M.1    Samanin, R.2
  • 23
    • 0031684125 scopus 로고    scopus 로고
    • Citicoline treatment for experimental intracerebral hemorrhage in mice
    • Clark W., Gunion-Rinker L., Lessov N., Hazel K. Citicoline treatment for experimental intracerebral hemorrhage in mice. Stroke. 29:1998;2136-2140.
    • (1998) Stroke , vol.29 , pp. 2136-2140
    • Clark, W.1    Gunion-Rinker, L.2    Lessov, N.3    Hazel, K.4
  • 24
    • 0030760430 scopus 로고    scopus 로고
    • A randomized dose-response trial of citicoline in acute ischemic stroke patients
    • Clark W.M., Warach S.J., Pettigrew L.C., Gammans R.E., Sabounjian L.A. A randomized dose-response trial of citicoline in acute ischemic stroke patients. Neurology. 49:1997;671-678.
    • (1997) Neurology , vol.49 , pp. 671-678
    • Clark, W.M.1    Warach, S.J.2    Pettigrew, L.C.3    Gammans, R.E.4    Sabounjian, L.A.5
  • 25
    • 0017291039 scopus 로고
    • Brain acetylcholine: Control by dietary choline
    • Cohen E.L., Wurtman R.J. Brain acetylcholine: Control by dietary choline. Science. 191:1976;561-562.
    • (1976) Science , vol.191 , pp. 561-562
    • Cohen, E.L.1    Wurtman, R.J.2
  • 26
    • 0020286778 scopus 로고
    • CDP-choline for cerebrovascular disorders: Clinical evaluation and evaluation of electrophysiological symptomology
    • Corso A., Arena M., Ventimiglia A., Bizzarro G., Campo G., Radalica F. CDP-choline for cerebrovascular disorders: Clinical evaluation and evaluation of electrophysiological symptomology. Clin. Ther. 102:1982;379-386.
    • (1982) Clin. Ther. , vol.102 , pp. 379-386
    • Corso, A.1    Arena, M.2    Ventimiglia, A.3    Bizzarro, G.4    Campo, G.5    Radalica, F.6
  • 27
    • 0026637566 scopus 로고
    • Enhancement by cytidine of membrane phospholipid synthesis
    • Coviella I.L., Wurtman R.J. Enhancement by cytidine of membrane phospholipid synthesis. Journal of Neurochemistry. 59:1992;338-343.
    • (1992) Journal of Neurochemistry , vol.59 , pp. 338-343
    • Coviella, I.L.1    Wurtman, R.J.2
  • 28
    • 0020653590 scopus 로고
    • Phospholipid metabolism during central and peripheral damage and recovery in nervous tissue
    • De Medio G.E., Brunett M., Dorman R.V. Phospholipid metabolism during central and peripheral damage and recovery in nervous tissue. Birth Defects Original article series. 19:1983;175-187.
    • (1983) Birth Defects Original article series , vol.19 , pp. 175-187
    • De Medio, G.E.1    Brunett, M.2    Dorman, R.V.3
  • 29
    • 0030907699 scopus 로고    scopus 로고
    • Effects of CDP-choline treatment on neurobehavioral deficits after TBI and on hippocampal and neocortical acetylcholine release
    • Dixon C.E., Ma X., Marion D.W. Effects of CDP-choline treatment on neurobehavioral deficits after TBI and on hippocampal and neocortical acetylcholine release. Journal of Neurotrauma. 14:1997;161-169.
    • (1997) Journal of Neurotrauma , vol.14 , pp. 161-169
    • Dixon, C.E.1    Ma, X.2    Marion, D.W.3
  • 31
    • 0025442377 scopus 로고
    • Role of prefrontal cortex and striatal output systems in short-term memory deficits associated with ageing, basal forebrain lesions, and cholinergic-rich grafts
    • Dunnett S.B. Role of prefrontal cortex and striatal output systems in short-term memory deficits associated with ageing, basal forebrain lesions, and cholinergic-rich grafts. Canadian Journal of Psycholology. 44:1990;210-232.
    • (1990) Canadian Journal of Psycholology , vol.44 , pp. 210-232
    • Dunnett, S.B.1
  • 33
    • 0025611798 scopus 로고
    • Cholinergic blockade in prefrontal cortex and hippocampus disrupts short-term memory in rats
    • Dunnett S.B., Wareham A.T., Torres E.M. Cholinergic blockade in prefrontal cortex and hippocampus disrupts short-term memory in rats. Neuroreport. 1:1990;61-64.
    • (1990) Neuroreport , vol.1 , pp. 61-64
    • Dunnett, S.B.1    Wareham, A.T.2    Torres, E.M.3
  • 35
    • 0029085870 scopus 로고
    • Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia
    • Freedman R., Hall M., Adler L.E., Leonard S. Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biological Psychiatry. 38:1995;22-33.
    • (1995) Biological Psychiatry , vol.38 , pp. 22-33
    • Freedman, R.1    Hall, M.2    Adler, L.E.3    Leonard, S.4
  • 36
    • 0030682093 scopus 로고    scopus 로고
    • Cognitive impairment in spontaneously hypertensive rats: Role of central nicotinic receptors.I
    • Gattu M., Pauly J.R., Boss K.L., Summers J.B., Buccafusco J.J. Cognitive impairment in spontaneously hypertensive rats: Role of central nicotinic receptors.I. Brain Research. 771:1997;89-103.
    • (1997) Brain Research , vol.771 , pp. 89-103
    • Gattu, M.1    Pauly, J.R.2    Boss, K.L.3    Summers, J.B.4    Buccafusco, J.J.5
  • 37
    • 0030664205 scopus 로고    scopus 로고
    • Cognitive impairment in spontaneously hypertensive rats: Role of central nicotinic receptors. Part II
    • Gattu M., Terry A.V. Jr., Pauly J.R., Buccafusco J.J. Cognitive impairment in spontaneously hypertensive rats: Role of central nicotinic receptors. Part II. Brain Research. 771:1997;104-114.
    • (1997) Brain Research , vol.771 , pp. 104-114
    • Gattu, M.1    Terry A.V., Jr.2    Pauly, J.R.3    Buccafusco, J.J.4
  • 38
    • 0344500821 scopus 로고    scopus 로고
    • Cytidine diphosphate choline administration activates brain cytidine triphosphate: Phosphocholine cytidylytransferase in aged rats
    • Gimenez R., Soler S., Aguilar J. Cytidine diphosphate choline administration activates brain cytidine triphosphate: Phosphocholine cytidylytransferase in aged rats. Neuroscience Letters. 273:1999;163-166.
    • (1999) Neuroscience Letters , vol.273 , pp. 163-166
    • Gimenez, R.1    Soler, S.2    Aguilar, J.3
  • 40
    • 0025277376 scopus 로고
    • Study of the effects of oral administration of CDP-choline on open-field behaviour under conditions of chronic hypoxia
    • Hamdorf G., Cervos-Navarro J. Study of the effects of oral administration of CDP-choline on open-field behaviour under conditions of chronic hypoxia. Arzneimittelforschung. 40:1990;519-522.
    • (1990) Arzneimittelforschung , vol.40 , pp. 519-522
    • Hamdorf, G.1    Cervos-Navarro, J.2
  • 41
    • 0343517069 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors during prenatal development and brain pathology in human aging
    • Hellstrom-Lindahl E., Court J.A. Nicotinic acetylcholine receptors during prenatal development and brain pathology in human aging. Behavioral Brain Research. 113:2000;159-168.
    • (2000) Behavioral Brain Research , vol.113 , pp. 159-168
    • Hellstrom-Lindahl, E.1    Court, J.A.2
  • 42
    • 0033957872 scopus 로고    scopus 로고
    • WKHA rats with genetic hyperactivity and hyperreactivity to stress: A review
    • Hendley E.D. WKHA rats with genetic hyperactivity and hyperreactivity to stress: A review. Neuroscience and Biobehavioral Review. 24:2000;41-44.
    • (2000) Neuroscience and Biobehavioral Review , vol.24 , pp. 41-44
    • Hendley, E.D.1
  • 43
    • 0018092725 scopus 로고
    • Relations between dietary choline or lecithin intake, serum choline levels, and various metabolic indices
    • Hirsch M.J., Crowden J.H., Wurtman R.J. Relations between dietary choline or lecithin intake, serum choline levels, and various metabolic indices. Metabolism. 27:1978;953-960.
    • (1978) Metabolism , vol.27 , pp. 953-960
    • Hirsch, M.J.1    Crowden, J.H.2    Wurtman, R.J.3
  • 44
    • 0029688243 scopus 로고    scopus 로고
    • Behavioral variability in SHR and WKY rats as a function of rearing environment and reinforcement contingency
    • Hunziker M.H., Saldana R.L., Neuringer A. Behavioral variability in SHR and WKY rats as a function of rearing environment and reinforcement contingency. Journal of the Experimental Analysis of Behavior. 65:1996;129-144.
    • (1996) Journal of the Experimental Analysis of Behavior , vol.65 , pp. 129-144
    • Hunziker, M.H.1    Saldana, R.L.2    Neuringer, A.3
  • 45
    • 0038098280 scopus 로고    scopus 로고
    • Effects of ICSS reinforcement parameters on the hyperactive behavior of the Spontaneously Hypertensive rat (SHR), an animal model of ADHD
    • Johansen, E. B., & Sagvolden, T., (2001). Effects of ICSS reinforcement parameters on the hyperactive behavior of the Spontaneously Hypertensive rat (SHR), an animal model of ADHD. Society of Neuroscience Abstracts 533.18.
    • (2001) Society of Neuroscience Abstracts , pp. 53318
    • Johansen, E.B.1    Sagvolden, T.2
  • 46
    • 0033485390 scopus 로고    scopus 로고
    • Nicotinic receptors in the brain: Correlating physiology with function
    • Jones S., Sudweeks S., Yakel J.L. Nicotinic receptors in the brain: Correlating physiology with function. Trends in Neuroscience. 22:1999;555-561.
    • (1999) Trends in Neuroscience , vol.22 , pp. 555-561
    • Jones, S.1    Sudweeks, S.2    Yakel, J.L.3
  • 47
    • 0023872375 scopus 로고
    • Effects of CDP-choline on neurologic deficits and cerebral glucose metabolism in a rat model of cerebral ischemia
    • Kakihana M., Fukuda N., Suno M., Nagaoka A. Effects of CDP-choline on neurologic deficits and cerebral glucose metabolism in a rat model of cerebral ischemia. Stroke. 19:1988;217-222.
    • (1988) Stroke , vol.19 , pp. 217-222
    • Kakihana, M.1    Fukuda, N.2    Suno, M.3    Nagaoka, A.4
  • 48
    • 0033991521 scopus 로고    scopus 로고
    • Early androgen treatment decreases cognitive function and catecholamine innervation in an animal model of ADHD
    • King J.A., Barkley R.A., Delville Y., Ferris C.F. Early androgen treatment decreases cognitive function and catecholamine innervation in an animal model of ADHD. Behavioral Brain Research. 107:2000;35-43.
    • (2000) Behavioral Brain Research , vol.107 , pp. 35-43
    • King, J.A.1    Barkley, R.A.2    Delville, Y.3    Ferris, C.F.4
  • 50
    • 0033586339 scopus 로고    scopus 로고
    • Enhancement of free fatty acid incorporation into phospholipids by choline plus cytidine
    • Knapp S., Wurtman R.J. Enhancement of free fatty acid incorporation into phospholipids by choline plus cytidine. Brain Research. 822(1-2):1999;52-59.
    • (1999) Brain Research , vol.822 , Issue.1-2 , pp. 52-59
    • Knapp, S.1    Wurtman, R.J.2
  • 52
    • 0026637566 scopus 로고
    • Enhancement by cytidine of brain membrane phospholipid synthesis
    • Lopez-Coviella I., Wurtman R.J. Enhancement by cytidine of brain membrane phospholipid synthesis. Journal of Neurochemistry. 59:1992;338-343.
    • (1992) Journal of Neurochemistry , vol.59 , pp. 338-343
    • Lopez-Coviella, I.1    Wurtman, R.J.2
  • 53
    • 0029115402 scopus 로고
    • ′ -cytidinediphosphocholine can affect brain phospholipid composition by increasing choline and cytidine plasma levels
    • ′ -cytidinediphosphocholine can affect brain phospholipid composition by increasing choline and cytidine plasma levels Journal of Neurochemistry. 65:1992;889-894.
    • (1992) Journal of Neurochemistry , vol.65 , pp. 889-894
    • Lopez-Coviella, I.1    Agut, J.2    Ortiz, J.A.3    Wurtman, R.J.4
  • 55
    • 0023262429 scopus 로고
    • ′ -diphosphocholine (CDP-choline) following oral and intravenous administration to the human and the rat
    • ′ -diphosphocholine (CDP-choline) following oral and intravenous administration to the human and the rat Neurochemistry International. 11:1987;293-297.
    • (1987) Neurochemistry International , vol.11 , pp. 293-297
    • Lopez-Coviella, I.1    Agut, J.2    Wurtman, R.J.3
  • 56
    • 0030221282 scopus 로고    scopus 로고
    • Effects of aging and hypertension on learning, memory and activity in rats
    • Meneses A., Castillo C., Ibarra M., Hong E. Effects of aging and hypertension on learning, memory and activity in rats. Physiology & Behavior. 60:1996;341-345.
    • (1996) Physiology & Behavior , vol.60 , pp. 341-345
    • Meneses, A.1    Castillo, C.2    Ibarra, M.3    Hong, E.4
  • 57
    • 0031954591 scopus 로고    scopus 로고
    • Spontaneously hypertensive rats: A potential model to identify drugs for treatment of learning disorders
    • Meneses A., Hong E. Spontaneously hypertensive rats: A potential model to identify drugs for treatment of learning disorders. Hypertension. 31:1998;968-972.
    • (1998) Hypertension , vol.31 , pp. 968-972
    • Meneses, A.1    Hong, E.2
  • 59
    • 0034603524 scopus 로고    scopus 로고
    • Risk factors for cerebral hypoperfusion, mild cognitive impairment, and dementia
    • Meyer J.S., Rauch G., Rauch R.A., Haque A. Risk factors for cerebral hypoperfusion, mild cognitive impairment, and dementia. Neurobiology of Aging. 21:2000;161-169.
    • (2000) Neurobiology of Aging , vol.21 , pp. 161-169
    • Meyer, J.S.1    Rauch, G.2    Rauch, R.A.3    Haque, A.4
  • 60
    • 0020326450 scopus 로고
    • Choline administration elevates brain phosphorylcholine concentrations
    • Millington W.R., Wurtman R.J. Choline administration elevates brain phosphorylcholine concentrations. Journal of Neurochemistry. 38:1982;1748-1752.
    • (1982) Journal of Neurochemistry , vol.38 , pp. 1748-1752
    • Millington, W.R.1    Wurtman, R.J.2
  • 61
    • 0028951029 scopus 로고
    • Impaired maze learning and cerebral glucose utilization in aged hypertensive rats
    • Mori S., Kato M., Fujishima M. Impaired maze learning and cerebral glucose utilization in aged hypertensive rats. Hypertension. 25:1995;545-553.
    • (1995) Hypertension , vol.25 , pp. 545-553
    • Mori, S.1    Kato, M.2    Fujishima, M.3
  • 63
    • 0029898666 scopus 로고    scopus 로고
    • The cerebral cortex of the rat and visual attentional function: Dissociable effects of mediofrontal, cingulate, anterior dorsolateral, and parietal cortex lesions on a five-choice serial reaction time task
    • Muir J.L., Everitt B.J., Robbins T.W. The cerebral cortex of the rat and visual attentional function: Dissociable effects of mediofrontal, cingulate, anterior dorsolateral, and parietal cortex lesions on a five-choice serial reaction time task. Cerebral Cortex. 6:1996;470-481.
    • (1996) Cerebral Cortex , vol.6 , pp. 470-481
    • Muir, J.L.1    Everitt, B.J.2    Robbins, T.W.3
  • 64
    • 0033382563 scopus 로고    scopus 로고
    • Decline in visual attention and spatial memory in aged rats
    • Muir J.L., Fischer W., Bjorklund A. Decline in visual attention and spatial memory in aged rats. Neurobiology of Aging. 20:1999;605-615.
    • (1999) Neurobiology of Aging , vol.20 , pp. 605-615
    • Muir, J.L.1    Fischer, W.2    Bjorklund, A.3
  • 67
    • 0037760777 scopus 로고    scopus 로고
    • Spontaneously Hypertensive rat (SHR) behavior in an operant model of attention-deficit hyperactive disorder (ADHD): Possible effects of methylphenidate on impulsivity
    • Nikkel, A. L., Decker, M. W., Fox, G. B., & Bitner, R. S. (2001). Spontaneously Hypertensive rat (SHR) behavior in an operant model of attention-deficit hyperactive disorder (ADHD): Possible effects of methylphenidate on impulsivity. Society of Neuroscicence Abstracts, 851.3.
    • (2001) Society of Neuroscicence Abstracts , pp. 8513
    • Nikkel, A.L.1    Decker, M.W.2    Fox, G.B.3    Bitner, R.S.4
  • 68
    • 0028890920 scopus 로고
    • Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology
    • Perry E.K., Morris C.M., Court J.A., Cheng A., Fairbairn A.F., McKeith I.G., Irving D., Brown A., Perry R.H. Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology. Neuroscience. 64:1995;385-395.
    • (1995) Neuroscience , vol.64 , pp. 385-395
    • Perry, E.K.1    Morris, C.M.2    Court, J.A.3    Cheng, A.4    Fairbairn, A.F.5    McKeith, I.G.6    Irving, D.7    Brown, A.8    Perry, R.H.9
  • 69
    • 0027320883 scopus 로고
    • Effects of cytidine diphosphate choline on rats with memory deficits
    • Petkov V.D., Kehayov R.A.et al. Effects of cytidine diphosphate choline on rats with memory deficits. Arzneimittelforschung. 43:1993;822-828.
    • (1993) Arzneimittelforschung , vol.43 , pp. 822-828
    • Petkov, V.D.1    Kehayov, R.A.2
  • 71
    • 0037051147 scopus 로고    scopus 로고
    • Hypodopaminergic and hypernoradrenergic activity in prefrontal cortex slices of an animal model for attention-deficit hyperactivity disorder - The spontaneously hypertensive rat
    • Russell V.A. Hypodopaminergic and hypernoradrenergic activity in prefrontal cortex slices of an animal model for attention-deficit hyperactivity disorder - the spontaneously hypertensive rat. Behavioral Brain Research. 130:2002;191-196.
    • (2002) Behavioral Brain Research , vol.130 , pp. 191-196
    • Russell, V.A.1
  • 72
    • 0034694887 scopus 로고    scopus 로고
    • Increased noradrenergic activity in prefrontal cortex slices of an animal model for attention-deficit hyperactivity disorder - The spontaneously hypertensive rat
    • Russell V., Allie S., Wiggins T. Increased noradrenergic activity in prefrontal cortex slices of an animal model for attention-deficit hyperactivity disorder - the spontaneously hypertensive rat. Behavioral Brain Research. 117:2000;69-74.
    • (2000) Behavioral Brain Research , vol.117 , pp. 69-74
    • Russell, V.1    Allie, S.2    Wiggins, T.3
  • 73
    • 0032127162 scopus 로고    scopus 로고
    • Differences between electrically-, Ritalin- and D-amphetamine-stimulated release of [3H]dopamine from brain slices suggest impaired vesicular storage of dopamine in an animal model of attention-deficit hyperactivity disorder
    • Russell V., de Villiers A., Sagvolden T., Lamm M., Taljaard J. Differences between electrically-, Ritalin- and D-amphetamine-stimulated release of [3H]dopamine from brain slices suggest impaired vesicular storage of dopamine in an animal model of attention-deficit hyperactivity disorder. Behavioral Brain Research. 94:1998;163-171.
    • (1998) Behavioral Brain Research , vol.94 , pp. 163-171
    • Russell, V.1    De Villiers, A.2    Sagvolden, T.3    Lamm, M.4    Taljaard, J.5
  • 74
    • 0034665603 scopus 로고    scopus 로고
    • Methylphenidate affects striatal dopamine differently in an animal model for attention-deficit/hyperactivity disorder - The spontaneously hypertensive rat
    • Russell V.A., de Villiers A.S., Sagvolden T., Lamm M.C., Taljaard J.J. Methylphenidate affects striatal dopamine differently in an animal model for attention-deficit/hyperactivity disorder - the spontaneously hypertensive rat. Brain Research Bulletin. 53:2000;187-192.
    • (2000) Brain Research Bulletin , vol.53 , pp. 187-192
    • Russell, V.A.1    De Villiers, A.S.2    Sagvolden, T.3    Lamm, M.C.4    Taljaard, J.J.5
  • 75
    • 0033962321 scopus 로고    scopus 로고
    • Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of attention-deficit/hyperactivity disorder (AD/HD)
    • Sagvolden T. Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of attention-deficit/hyperactivity disorder (AD/HD). Neuroscience and Biobehavioral Review. 24:2000;31-39.
    • (2000) Neuroscience and Biobehavioral Review , vol.24 , pp. 31-39
    • Sagvolden, T.1
  • 78
    • 0024467575 scopus 로고
    • Choline: An essential dietary nutrient?
    • Sheard N.F., Zeisel S.H. Choline: An essential dietary nutrient? Nutrition. 5:1989;1-5.
    • (1989) Nutrition , vol.5 , pp. 1-5
    • Sheard, N.F.1    Zeisel, S.H.2
  • 79
    • 0030002502 scopus 로고    scopus 로고
    • Citicoline improves verbal memory in aging
    • Spiers P.A.D., Myers D.et al. Citicoline improves verbal memory in aging. Archives of Neurology. 53:1996;441-448.
    • (1996) Archives of Neurology , vol.53 , pp. 441-448
    • Spiers, P.A.D.1    Myers, D.2
  • 80
    • 0023860168 scopus 로고
    • Treatment of acute cerebral infarction with a choline precursor in a multicenter double-blind placebo-controlled study
    • Tazaki Y., Sakai F., Otomo E., Kutsuzawa T., Kameyama M., Omae T., Fujishima T. Treatment of acute cerebral infarction with a choline precursor in a multicenter double-blind placebo-controlled study. Stroke. 19:1988;211-216.
    • (1988) Stroke , vol.19 , pp. 211-216
    • Tazaki, Y.1    Sakai, F.2    Otomo, E.3    Kutsuzawa, T.4    Kameyama, M.5    Omae, T.6    Fujishima, T.7
  • 81
    • 0034619586 scopus 로고    scopus 로고
    • Deficits in spatial learning and nicotinic-acetylcholine receptors in older, spontaneously hypertensive rats
    • Terry A.V. Jr., Hernandez C.M., Buccafusco J.J., Gattu M. Deficits in spatial learning and nicotinic-acetylcholine receptors in older, spontaneously hypertensive rats. Neuroscience. 101:2000;357-368.
    • (2000) Neuroscience , vol.101 , pp. 357-368
    • Terry A.V., Jr.1    Hernandez, C.M.2    Buccafusco, J.J.3    Gattu, M.4
  • 82
    • 85031183596 scopus 로고    scopus 로고
    • Dietary CDP-choline supplementation alleviates age-associated reference memory deficits in rats
    • submitted
    • Teather, L. A., & Wurtman, R. J. (submitted). Dietary CDP-choline supplementation alleviates age-associated reference memory deficits in rats. Psychopharmacology.
    • Psychopharmacology
    • Teather, L.A.1    Wurtman, R.J.2
  • 83
    • 0032571764 scopus 로고    scopus 로고
    • Alterations with aging and ischemia in nicotinic acetylcholine receptor subunits α4 and β2 messenger RNA expression in postmortem human putamen. Implications for susceptibility to parkinsonism
    • Tohgi H., Utsugisawa K., Yoshimura M., Nagane Y., Mihara M. Alterations with aging and ischemia in nicotinic acetylcholine receptor subunits α4 and β2 messenger RNA expression in postmortem human putamen. Implications for susceptibility to parkinsonism. Brain Research. 791:1998;186-189.
    • (1998) Brain Research , vol.791 , pp. 186-189
    • Tohgi, H.1    Utsugisawa, K.2    Yoshimura, M.3    Nagane, Y.4    Mihara, M.5
  • 84
    • 0028896412 scopus 로고
    • Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline
    • Weiss G.B. Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline. Life Science. 56(9):1995;637-660.
    • (1995) Life Science , vol.56 , Issue.9 , pp. 637-660
    • Weiss, G.B.1
  • 85
    • 0034308088 scopus 로고    scopus 로고
    • Effect of oral CDP-choline on plasma choline and uridine levels in humans
    • Wurtman R.J., Regan M., Ulus I., Yu L. Effect of oral CDP-choline on plasma choline and uridine levels in humans. Biochemical Pharmacology. 60:2000;89-92.
    • (2000) Biochemical Pharmacology , vol.60 , pp. 89-92
    • Wurtman, R.J.1    Regan, M.2    Ulus, I.3    Yu, L.4
  • 86
    • 0026674166 scopus 로고
    • Impaired learning and memory in mature spontaneously hypertensive rats
    • Wyss J.M., Fisk G., van Groen T. Impaired learning and memory in mature spontaneously hypertensive rats. Brain Research. 592:1992;135-140.
    • (1992) Brain Research , vol.592 , pp. 135-140
    • Wyss, J.M.1    Fisk, G.2    Van Groen, T.3
  • 87
    • 0034282323 scopus 로고    scopus 로고
    • Age-related decline in water maze learning and memory in rats: Strain differences
    • Wyss J.M., Chambless B.D., Kadish I., van Groen T. Age-related decline in water maze learning and memory in rats: Strain differences. Neurobiology of Aging. 21:2000;671-681.
    • (2000) Neurobiology of Aging , vol.21 , pp. 671-681
    • Wyss, J.M.1    Chambless, B.D.2    Kadish, I.3    Van Groen, T.4
  • 88
    • 0025330373 scopus 로고
    • Pharmacological actions of a new TRH analogue, YM-14673, in rats subjected to cerebral ischemia and anoxia
    • Yamamoto M., Shimizu M., Okamiya H. Pharmacological actions of a new TRH analogue, YM-14673, in rats subjected to cerebral ischemia and anoxia. European Journal of Pharmacology. 181:1990;207-214.
    • (1990) European Journal of Pharmacology , vol.181 , pp. 207-214
    • Yamamoto, M.1    Shimizu, M.2    Okamiya, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.