Regulation of hepatic GLUT8 expression in normal and diabetic models

Endocrinology

Volumn 144, Issue 5, 2003, Pages 1703-1711

  Gorovits, Naira ^a   Cui, Lingguang ^a   Busik, Julia V ^b   Ranalletta, Mollie ^a   De Mouzon, Sylvie Hauguel ^c   Charron, Maureen J ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER; INSULIN; MESSENGER RNA; PROTEIN GLUT8; STREPTOZOCIN; UNCLASSIFIED DRUG; GLUCOSE TRANSPORTER 4; MUSCLE PROTEIN; SLC2A4 PROTEIN, MOUSE; SLC2A8 PROTEIN, MOUSE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT SYSTEM; HETEROZYGOTE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; INSULIN DEPENDENT DIABETES MELLITUS; LIVER; MOUSE; NEWBORN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WILD TYPE; ANIMAL; CBA MOUSE; EXPERIMENTAL DIABETES MELLITUS; FEMALE; FETUS; GENE DELETION; GENETICS; IMMUNOLOGICAL PROCEDURES; METABOLISM; PRENATAL DEVELOPMENT; REFERENCE VALUE;

ANIMALS; ANIMALS, NEWBORN; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; FEMALE; FETUS; GENE DELETION; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; GLUCOSE TRANSPORTER TYPE 4; HETEROZYGOTE; IMMUNOLOGIC TECHNIQUES; LIVER; MICE; MICE, INBRED CBA; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; REFERENCE VALUES; RNA, MESSENGER;

EID: 0037734151     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220968     Document Type: Article

References (33)

1. Katz EB, Stenbit AE, Hatton K, DePinho R, Charron MJ 1995 Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4. Nature 377:151-155
2. Charron MJ, Katz EB, Olson AL 1999 GLUT4 gene regulation and manipulation. J Biol Chem 274:3253-3256
3. Ibberson M, Uldry M, Thorens B 2000 GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues. J Biol Chem 275:4607-4612
4. Doege H, Schurmann A, Bahrenberg G, Brauers A, Joost HG 2000 GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity. J Biol Chem 275:16275-16280
5. Carayannopoulos MO, Chi MM, Cui Y, Pingsterhaus JM, McKnight RA, Mueckler M, Devaskar SU, Moley KH 2000 GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst. Proc Natl Acad Sci USA 97:7313-7318
6. Reagan LP, Gorovits N, Hoskin EK, Alves SE, Katz EB, Grillo CA, Piroli GG, McEwen BS, Charron MJ 2001 Localization and regulation of GLUTx1 glucose transporter in the hippocampus of streptozotocin diabetic rats. Proc Natl Acad Sci USA 98:2820-2825
7. Scheepers A, Doege H, Joost HG, Schurmann A 2001 Mouse GLUT8: genomic organization and regulation of expression in 3T3-L1 adipocytes by glucose. Biochem Biophys Res Commun 288:969-974
8. Lisinski I, Schurmann A, Joost HG, Cushman SW, Al-Hasani H 2001 Targeting of GLUT6 (formerly GLUT9) and GLUT8 in rat adipose cells Biochem J 358:517-522
9. Pinto AB, Carayannopoulos MO, Hoehn A, Dowd L, Moley KH 2002 Glucose transporter 8 expression and translocation are critical for murine blastocyst survival. Biol Reprod 66:1729-1733
10. Thorens B 1996 Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes. Am J Physiol 270:G541-G553
11. Thorens B, Flier JS, Lodish HF, Kahn BB 1990 Differential regulation of two glucose transporters in rat liver by fasting and refeeding and by diabetes and insulin treatment Diabetes 39:712-719
12. Tal M, Schneider DL, Thorens B, Lodish HF 1990 Restricted expression of the erythroid/brain glucose transporter isoform to perivenous hepatocytes in rats. Modulation by glucose. J Clin Invest 86:986-992
13. Guillam MT, Burcelin R, Thorens B 1998 Normal Hepatic glucose production in the absence of GLUT2 reveals an alternative pathway for glucvose release from hepatocytes. Proc Natl Acad Sci USA 95:12317-12321
14. Burcelin R, del Carmen Munoz M, Guillam MT, Thorens B 2000 Liver hyperplasia and paradoxical regulation of glycogen metabolism and glucose-sensitive gene expression in GLUT2-null hepatocytes. Further evidence for the existence of a membrane-based glucose release pathway. J Biol Chem 275:10930-10936
15. Thorens B, Guillam MT, Beermann F, Burcelin R, Jaquet M 2000 Transgenic reexpression of GLUT1 or GLUT2 in pancreatic β cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion. J Biol Chem 275:23751-23758
16. Guillam MT, Dupraz P, Thorens B 2000 Glucose uptake, utilization, and signaling in GLUT2-null islets. Diabetes 49:1485-1491
17. Stenbit AE, Tsao TS, Li J, Burcelin R, Geenen DL, Factor SM, Houseknecht K, Katz EB, Charron MJ 1997 GLUT4 heterozygous knockout mice develop muscle insulin resistance and diabetes. Nat Med 3:1096-1101
18. Burcelin R, Mrejen C, Decaux JF, De Mouzon SH, Girard J, Charron MJ 1998 In vivo and in vitro regulation of hepatic glucagon receptor mRNA concentration by glucose metabolism. J Biol Chem 273:8088-8093
19. Baldini G, Hohman R, Charron MJ, Lodish HF 1991 Insulin and nonhydrolyzable GTP analogs induce translocation of GLUT 4 to the plasma membrane in α-toxin-permeabilized rat adipose cells. J Biol Chem 266:4037-4040
20. Yu H, Bauer B, Lipke GK, Phillips RL, Van Zant G 1993 Apoptosis and hematopoiesis in murine fetal liver. Blood 81:373-384
21. Hsu SC, Molday RS 1991 Glycolytic enzymes and a GLUT-1 glucose transporter in the outer segments of rod and cone photoreceptor cells. J Biol Chem 266:21745-21752
22. Leturque A, Postic C, Ferre P, Girard J 1991 Nutritional regulation of glucose transporter in muscle and adipose tissue of weaned rats. Am J Physiol 260:E588-E593
23. Jungermann K 1986 Dynamics of zonal hepatocyte heterogeneity. Perinatal development and adaptive alterations during regeneration after partial hepatectomy, starvation and diabetes. Acta Histochem Suppl 32:89-98
24. Jungermann K 1987 Metabolic zonation of liver parenchyma: significance for the regulation of glycogen metabolism, gluconeogenesis, and glycolysis. Diabetes Metab Rev 3:269-293
25. Jungermann K 1992 Zonal liver cell heterogeneity. Enzyme 46:5-7
26. Probst I, Schwartz P, Jungermann K 1982 Induction in primary culture of 'gluconeogenic' and 'glycolytic' hepatocytes resembling periportal and perivenous cells. Eur J Biochem 126:271-278
27. Piroli GG, Grillo CA, Hoskin EK, Znamensky V, Katz EB, Milner TA, McEwen BS, Charron MJ, Reagan LP 2002 Peripheral glucose administration stimulates the translocation of GLUT8 glucose transporter to the endoplasmatic reticulum in the rat hippocampus. J Comp Neurol 452:103-114
28. Postic C, Burcelin R, Rencurel F, Pegorier JP, Loizeau M, Girard J, Leturque A 1993 Evidence for a transient inhibitory effect of insulin on GLUT2 expression in the liver: studies in vivo and in vitro. Biochem J 293:119-124
29. Prip-Buus C, Perdereau D, Foufelle F, Maury J, Ferre P, Girard J 1995 Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes. Dependency upon glucokinase activity. Eur J Biochem 230:309-315
30. Rencurel F, Waeber G, Antoine B, Rocchiccioli F, Maulard P, Girard J, Leturque A 1996 Requirement of glucose metabolism for regulation of glucose transporter type 2 (GLUT2) gene expression in liver. Biochem J 314:903-909
31. Shih HM, Towle HC 1992 Definition of the carbohydrate response element of the rat S14 gene. Evidence for a common factor required for carbohydrate regulation of hepatic genes. J Biol Chem 267:13222-13228
32. Burcelin R, Eddouks M, Kande J, Assan R, Girard J 1992 Evidence that GLUT-2 mRNA and protein concentrations are decreased by hyperinsulinaemia and increased by hyperglycaemia in liver of diabetic rats [published erratum appears in Biochem J 1993 Feb 1;289(Part 3):928]. Biochem J 288:675-679
33. Decaux JF, Antoine B, Kahn A 1989 Regulation of the expression of the L-type pyruvate kinase gene in adult rat hepatocytes in primary culture. J Biol Chem 264:11584-11590