Endostatin capture from Pichia pastoris culture in a fluidized bed - From on-chip process optimization to application

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 790, Issue 1-2, 2003, Pages 327-336

  Shiloach, Joseph ^a   Santambien, Patrick ^b   Trinh, Loc ^a   Schapman, Anthony ^b   Boschetti, Egisto ^b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b BioSepra SA   (France)

Author keywords

Chip technology; Endostatin; Fluidized bed; Pichia pastoris; Proteins; Yeast

Indexed keywords

BIOMASS; CENTRIFUGATION; CHROMATOGRAPHIC ANALYSIS; FILTRATION; FLUIDIZATION; FLUIDIZED BEDS; ION EXCHANGE; MASS SPECTROMETRY; MICROORGANISMS; ZIRCONIA;

BIOMASS CONCENTRATIONS;

YEAST;

ENDOSTATIN; METAL CHELATE; RESIN; ZIRCONIUM OXIDE;

ADSORPTION; ANION EXCHANGE; ARTICLE; BIOFILTRATION; BIOTECHNOLOGY; CATION EXCHANGE; CELL DENSITY; CENTRIFUGATION; CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); ELUTION; FLOW RATE; FLUIDIZATION; FLUIDIZED BED; FUNGAL BIOMASS; FUNGUS CULTURE; FUNGUS GROWTH; HYDROPHOBICITY; LABORATORY; LABORATORY TEST; MASS SPECTROMETRY; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN ISOLATION; SEPARATION TECHNIQUE; VELOCITY; WEIGHT;

PICHIA; PICHIA PASTORIS;

EID: 0037725182     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(03)00097-7     Document Type: Article

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