Expression of deleted in malignant brain tumor- 1 (DMBT1) molecule in biliary epithelium is augmented in hepatolithiasis: Possible participation in lithogenesis

Digestive Diseases and Sciences

Volumn 48, Issue 7, 2003, Pages 1234-1240

  Sasaki, Motoko ^a   Huang, Shiu Feng ^b   Chen, Miin Fu ^b   Jan, Yi Yin ^b   Yeh, Ta Sen ^b   Ishikawa, Akira ^a,c   Mollenhauer, Jan ^d   Poustka, Annemarie ^d   Tsuneyama, Koichi ^a   Nimura, Yuji ^c   Oda, Koji ^c   Nakanuma, Yasuni ^a  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Bile duct; Deleted in malignant brain tumor 1 (DMBT1); Hepatolithiasis

Indexed keywords

CHOLESTEROL; DELETED IN MALIGNANT BRAIN TUMOR 1 MOLECULE; MUCIN; UNCLASSIFIED DRUG;

ARTICLE; BILE DUCT OBSTRUCTION; BILE DUCT STONE; CONTROLLED STUDY; CRYSTALLIZATION; GALLBLADDER EPITHELIUM; HEPATOBILIARY DISEASE; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIVER; PRIMARY SCLEROSING CHOLANGITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STONE FORMATION;

AGGLUTININS; BILE DUCTS; BILE DUCTS, INTRAHEPATIC; CHOLELITHIASIS; CHOLESTEROL; EPITHELIUM; HUMANS; RECEPTORS, CELL SURFACE; RNA, MESSENGER;

EID: 0037712151     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024186504893     Document Type: Article

References (26)

1. Nakanuma Y, Yamaguchi K, Ohta G, Terada T: Pathologic features of hepatolithiasis in Japan. Hum Pathol 19:1181-1186, 1988
2. Nakayama F, Soloway R, Nakama T: Hepatolithiasis in East Asia. retrospective study. Dig Dis Sci 31:21-26, 1986
3. Nakanuma Y, Sasaki M, Terada T, Harada K: Intrahepatic peribiliary glands of humans. II Pathological spectrum. J Gastroenterol Hepatol 9:80-86, 1994
4. Trotman B, Ostrow J, Soloway R: Pigment vs cholesterol cholelithiasis: composition of stone and bile composition. Am J Dig Dis 19:585-590, 1974
5. Sasaki M, Nakanuma Y, Kim Y: Expression of apomucins in the intrahepatic biliary tree in hepatolithiasis differs from that in normal liver and extrahepatic biliary obstruction. Hepatol 27:46-53, 1998
6. Shoda J, Tanaka N, Matsuzaki Y, Honda A, Osuga T, Shigematsu S, Miyazaki H: Microanalysis of bile acid composition in intrahepatic calculi and its etiological significance. Gastroenterology 101:821-830, 1991
7. Shoda J, Oda K, Suzuki H, Sugiyama Y, Ito K, Cohen DE, Feng L, Kamiya J, Nimura Y, Miyazaki H, Kano M, Matsuzaki Y, Tanaka N: Etiologic significance of defects in cholesterol, phospholipid, and bile acid metabolism in the liver of patients with intrahepatic calculi. Hepatology 33:1194-1205, 2001
8. Nunes DP, Afdhal NH, Offner GD: A recombinant bovine gallbladder mucin polypeptide binds biliary lipids and accelerates cholesterol crystal appearance time. Gastroenterology 116:936-942, 1999
9. Mollenhauer J, Herbertz S, Helmke B, Kollender G, Krebs I, Madsen J, Holmskov U, Sorger K, Schmitt L, Wiemann S, Otto HF, Grone HJ, Poustka A: Deleted in malignant brain tumors 1 Is a versatile mucin-like molecule likely to play a differential role in digestive tract cancer. Cancer Res 61:8880-8886, 2001
10. Mollenhauer J, Wiemann S, Scheurlen W, Korn B, Hayashi Y, Wilgenbus KK, von Deimling A, Poustka A: DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours. Nat Genet 17:32-39, 1997
11. Mollenhauer J, Holmskov U, Wiemann S, Krebs I, Herbertz S, Madsen J, Kioschis P, Coy JF, Poustka A: The genomic structure of the DMBT1 gene: evidence for a region with susceptibility to genomic instability. Oncogene 18:6233-6240, 1999
12. Mollenhauer J, Herbertz S, Holmskov U, Tolnay M, Krebs I, Merlo A, Schroder HD, Maier D, Breitling F, Wiemann S, Grone HJ, Poustka A: DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer. Cancer Res 60:1704-1710, 2000
13. Holmskov U, Lawson P, Teisner B, Tornoe I, Willis AC, Morgan C, Koch C, Reid KB: Isolation and characterization of a new memberof the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule. J Biol Chem 272:13743-13749, 1997
14. Tino MJ, Wright JR: Glycoprotein-340 binds surfactant protein-A (SP-A) and stimulates alveolar macrophage migration in an SP-A-independent manner. Am J Respir Cell Mol Biol 20:759-768, 1999
15. Nakanuma Y, Sasaki M: Expression of blood-group-related antigens in the intrahepatic biliary tree and hepatocytes in normal livers and various hepatobiliary diseases. Hepatology 10:174-178, 1989
16. Terada T, nakanuma Y, Ohta G: Glandular elements around the intrahepatic bile ducts in man: their morphology and distribution in normal livers. Liver 7:1-8, 1987
17. Cone R, Schlaepfer E: Improved in situ hybridization of HIV with RNA probes derived from PCR products. J Histochem Cytochem 45:721-727, 1997
18. Lowry O, Rosebrough N, Farr A, Randall R: Protein measurement with the Folin phenol reagent. J Biol Chem 193:265, 1951
19. Thornton DJ, Davies JR, Kirkham S, Gautrey A, Khan N, Richardson PS, Sheehan JK: Identification of a nonmucin glycoprotein (gp-340) from a purified respiratory mucin preparation: evidence for an association involving the MUC5B mucin. Glycobiology 11:969-977, 2001
20. 2 and their specific receptor in bile ducts of patients with intrahepatic calculi: factors of chronic proliferative cholangitis. Hepatology 29:1026-1036, 1999
21. Holmskov U, Mollenhauer J, Madsen J, Vitved L, Gronlund J, Tornoe I, Kliem A, Reid KB, Poustka A, Skjodt K: Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D. Proc Natl Acad Sci USA 96:10794-10799, 1999
22. Bikker F, Ligtenberg A, Nazmi K, Veerman E, Hof W, Bolscher J, Poustka A, Amerongen A, Mollenhauer J: Identification of the bacteria-binding peptide domain on salivary aggulutinin (gp-340/DMBT1), a member of the scavenger receptor-cystein rich superfamily. J Biol Chem 27:32104-32115, 2002
23. Madsen J, Kliem A, Tornoe I, Skjodt K, Koch C, Holmskov U: Localization of lung surfactant protein D on mucosal surfaces in human tissues. J Immunol 164:5866-5870, 2000
24. Park S, Oh R, Park J, Lee J, Shin M, Kim H, Lee H, Kim Y, Kim S, Lee S, Yoo N, Lee J: Somatic mutatious of the trefoil factor family gene in gastric cancer. Gastroenterology 119:691-698, 2000
25. Lefebvre O, Chenard M, Masson R, Linares J, Dierich A, Lemeur M, Wendling C, Tomasetto C, Chambon P, Rio M: Gastric mucosa abnormalities and tumorgenesis in mice lacking th pS2 trefoil protein. Science 274:259-262, 1996
26. Thim L, Mortz E: Isolation and characterization of putative trefoil peptide receptors. Regul Pept 90:61-68, 2000