Gras flavoring substances 21

Food Technology

Volumn 57, Issue 5, 2003, Pages 46-53

  Smith, R L ^a   Cohen, S M ^b   Doull, J ^c   Feron, V J ^d   Goodman, J I ^e   Marnett, L J ^f   Portoghese, P S ^g   Waddell, W J ^h   Wagner, B M ⁱ   Adams, T B ^j  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^d UTRECHT UNIVERSITY   (Netherlands)

^e MICHIGAN STATE UNIVERSITY   (United States)

^f VANDERBILT UNIVERSITY   (United States)

^g UNIVERSITY OF MINNESOTA   (United States)

^h University of Louisville School of Medicine   (United States)

ⁱ NEW YORK UNIVERSITY   (United States)

^j Federal Emergency Management Agency   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; BIOASSAY; LAWS AND LEGISLATION; METABOLISM; PHARMACOKINETICS; UNSATURATED COMPOUNDS;

SAFETY ASSESSMENT;

FLAVORS;

EID: 0037711055     PISSN: 00156639     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Review

References (39)

1. Adams, T.B., Hallagan, J.B., Putman, J.M., Gierke, T.L., Doull, J., Munro, I.C., Newberne, P.M., Portoghese, P.S., Smith, R.L., Wagner, B.M., Weil, C.S., Woods, L.A., and Ford, R.A. 1996. The FEMA GRAS assessment of alicyclic substances used as flavor ingredients. Food Chem. Toxicol. 34: 763-828.
2. Adams, T.B., Doull, J., Goodman, J.I., Munro, I.C., Newberne, P.M., Portoghese, P.S., Smith, R.L., Wagner, B.M., Weil, C.S., Woods, L.A., and Ford, R.A. 1997. The FEMA GRAS assessment of furiural used as a flavor ingredient. Food Chem. Toxicol. 35: 739-751.
3. Adams, T.B., Greer, D.B., Doull, J., Munro, I.C., Newberne, P.M., Portoghese, P.S., Smith, R.L., Wagner, B.M., Weil, C.S., Woods, L.A., and Ford, R.A. 1998. The FEMA GRAS assessment of lactones used as flavor ingredients. Food Chem. Toxicol. 36: 249-278.
4. Caldwell, J. 1992. Problems and opportunities in toxicity testing arising from species differences in xenobiotic metabolism. In "Toxicology from Discovery to Experimentation to the Human Perspective." ed. C.M.C.P.L Chambers, H.M. Bolt, and P. Preziosi, pp. 651-659. Elsevier, New York.
5. Caldwell, J. and Viswalingam, A. 1989. A comparative study of the hepatic effects of cinnamyl esters in mice. In "The Fifth international Congress of Toxicology," Elsevier, New York.
6. Clayson, D.B., Iverson, F., Nera E.A., and Lok, E. 1990. The significance of induced forestomach tumors. Ann. Rev. Pharmacol. Toxicol. 30: 441-463.
7. Grice, H.C. 1988. Safety evaluation of butylated hydroxyanisole from the perspective if effects in forestomach and oesophageal squamous epithelium Food Chem. Toxicol. 26: 717-723.
8. Hall, R.L. and Oser, B.L. 1965. Recent progress in the consideration of flavoring ingredients under the Food Additives Amendment. Food Technol. 19(2): 151-197.
9. Keyhanfar, F. ard Caldwell, J. 1996. Factors affecting the metabolism of cinnamyl anthranilate in the rat and mouse. Food Chem. Toxicol. 34: 241-249.
10. Lawrence, B.M. 1994a. Progress in essential oils (cassia oil). Perfumer Flavorist 19(4) 33.
11. Lawrence, B.M. 1994b. Progress in essential oils (cinnamon oil). Perfumer Flavorist 19(3):59.
12. Lucas, C.D. Putnam, J.M., and Hallagan, J.B. 1999. "Flavor and Extract Manufacturers Association of the United States 1995 Poundage and Technical Effects Update Survey." Flavor and Extract Manufacturers Assn., Washington D.C.
13. Maarse, H., Visscher, C.A.,Willemsens, L. C., and Boelens, M.H. 1999. "Volatile Components in Food-Qualitative and Quantitative Data.' Centraal Instituut Voor Voedingsonderzioek TNO,Zeist, The Netherlands.
14. NAS. 1970. "Evaluating the Safety of Food Chemicals." Natl. Academy of Sciences, Washington, D.C.
15. NAS. 1982. "Evaluating the Safety of Food Chemicals." Natl. Academy of Sciences, Washington, D.C.
16. NAS. 1987. "Evaluating the Safety of Food Chemicals." Natl. Academy of Sciences, Washington, D.C.
17. NCI. 1980. Bioassay of cinnamyl anthranilate for possible carcinogenicity. NCI-CG-TR-196. Natl. Cancer Inst., Bethesda, Md., and Natl. Toxicology Program, Research Triangle, N.C.
18. Newberne, P.M., Smith, R.L., Doull, J., Goodman, J.I., Munro, I.C., Portoghese, P.S., Wagner, B.M. Weil, C.S., Woods, L.A., Adams, T.B., Lucas, C.D., and Ford, R.A. 1999. The FEMA GRAS assessment of trans-anethole used as a flavoring substance Food Chem. Toxicol. 37: 789-811.
19. Newberne, P.M., Smith, R.L., Doull, J., Feron, V.J. Goodman, J.I., Munro, I.C., Portoghese, P.S., Waddell, W.J., Wagner, B.M., Weil, C.S., Adams, J.B., and Hallagan, J.B. 2000 19. GRAS flavoring substances. Food Technol. 54(6): 66-84.
20. NTP. 1980. Bioassay of cinnamyl anthranilate for possible carcinogenicity (CAS No. 87-29-6). NTP TR-196. Natl. Toxicology Program, Research Triangle, N.C.
21. NTP. 1986a. Toxicology and carcinogenesis studies of benzyl acetate (CAS No. 140-11-4) in F344/N rats and B6C3F1 Mice (gavage studies) NTP TR-250. Natl. Toxicology Program, Research Triangle, N.C.
22. NTP. 1986b Carcinogenesis studies of ethyl acrylate (CAS 140-88-5) in F344/N and B6C3F. mice (gavage studies). NTP TR 259. Natl. Toxicology Program, Research Triangle, N.C.
23. NTP. 1988. Toxicology and carcinogenesis studies of malonal-dehyde, sodium salt (3-hydroxy-2-propenal, sodium salt) (CAS No. 24382-04-5) in F344/N rats and B6C3F1 mice (gavage studies). NTP TR-331 Natl. Toxicology Program, Research Triangle N.C.
24. NTP. 1990a. Toxicology and Carcinogenesis studies of furfural (CAS No. 98-01-1) in F344/N rats and B6C3F1 mice (gavage studies). NTP TR-382. Natl. Toxicology Program, Research Triangle, N.C.
25. NTP. 1990b. Toxicology and carcinogenesis studies of 3,4-dihydrocoumarin (CAS No. 119-84-6) in F344/N rats and B6C3F1 mice (gavage studies). NTP TR-423. Natl. Toxicology Program, Research Triangle, N.C.
26. NTP. 1992. Toxicology and carcinogenesis studies of coumarin (CAS No. 91-64-5) in F344/N rats and B6C3F1 mice (gavage studies) NTP TR-422. Natl. Toxicology Program, Research Triangle, N.C.
27. NTP. 1993a. Toxicology and carcinogenesis studies of benzal-dehyde (CAS No. 100-52-7) in F344/N rats and B6C3F1 mice (gavage studies). NTP TR-378. Natl. Toxicology Program, Research Triangle, N.C.
28. NTP. 1993b. Toxicology and carcinogenesis studies of benzyl acetate (CAS No. 140-11-4) in F344/N rats and B6C3F1 mice feed studies). NTP TR-431. Natl. Toxicology Program, Research Triangle N.C.
29. NTP. 2000. 'Report on Carcinogens," 9th ed. Natl. Toxicology Program, Research Triangle, N.C.
30. NTP. 2001a. Draft report: Toxicology and carcinogenesis studies of 2,4-hexadienal (89% trans.trans isomer, Cas No. 142-83-6; 11% cis,trans isomer) in F344/N Rats and B6C3F1 Mice (gavage studies), NTP TR 509. Natl. Toxicology Program, Research Triangle, N.C.
31. NTP. 2001b. Draft report Toxicology and carcinogenesis studies of citral (microencapsulated) (CAS No. 5392-40-5) in F344/N rats and B6C3F1 mice (feed studies). NTP TR-505. Natl. Toxicology Program, Research Triangle, N.C.
32. NTP. 2002. Draft report: Toxicology and carcinogenesis studies of trans-cinnamaldehyde (microencapsulated) (CAS No. 14371-10-9) in F344/N rats and B6C3F, mice (feed studies). NTP TR 514. Natl. Toxicology Program, Research Triangle, N.C.
33. Smith, R.L. and Ford, R.A. 1993. Recent progress in consideration of flavoring ingredients under the Food Additives Amendment 16 GRAS Substances Food Technol. 47: 104-117.
34. Smith, R.L., Doull, J., Feron, V.J., Goodman, J.I., Marnett, L.J., Munro, I.C., Newberne, P.M., Portoghese, P.S., Waddell, W.J., Wagner, B.M., and Adams, T.B. 2002a. The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. Food Chem. Toxicol. 40: 429-451.
35. Smith, R.L. Adams, T.B., Doull, J., Feron, V.J., Goodman, J.I., Marnett, L.J., Portoghese P.S. Waddell W.J., Wagner, B.M., Rogers, A.E., Caldwell, J., and Sipes, I.G. 2002b. Safety assessment of aliylalkoxybenzene derivatives used as flavoring substances - Methyleugenol and estragole. Food Chem. Toxico1. 40: 851-870.
36. Stofberg, J. and Grundschober, F. 1987. Consumption ratio and food predominance of flavoring materials. Perfumer Flavorist 12: 27.
37. Viswalingam, A., Caldwell, J., Fournel, S., Schladt, L., and Oesch, F. 1988. Hepatic effects of cinnamyl anthranilate resemble those of a peroxisome proliferator in mouse, but not in rat. Brit. J. Pharmacol. 93: 32.
38. Waddell, W.J. 2002. Thresholds of carcinogenicity of flavors. Toxicol. Sci. 68:275-279.
39. Wester, P.W. and Kroes, R. 1988. Forestomach carcinogens: Pathology and relevance to man. Toxicol. Pathol. 16: 165-171.