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Volumn 34, Issue 9, 1996, Pages 763-828

The FEMA GRAS assessment of alicyclic substances used as flavour ingredients

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DERIVATIVE; ALDEHYDE DERIVATIVE; ALICYCLIC COMPOUND; CARBOXYLIC ACID DERIVATIVE; CYCLOHEXANONE DERIVATIVE; CYCLOPENTANONE DERIVATIVE; ESTER DERIVATIVE; FLAVORING AGENT;

EID: 0030250916     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(96)00051-8     Document Type: Review
Times cited : (54)

References (158)
  • 1
    • 0002467542 scopus 로고
    • Biotransformation and bioactivation of xenobiotics by the kidney
    • Edited by D. H. Hutson, J. Caldwell and G. D. Paulson. Taylor & Francis, New York
    • Anders M. W. (1989) Biotransformation and bioactivation of xenobiotics by the kidney. In Intermediary Xenobiotic Metabolism in Animals. Edited by D. H. Hutson, J. Caldwell and G. D. Paulson. pp. 81-97. Taylor & Francis, New York.
    • (1989) Intermediary Xenobiotic Metabolism in Animals , pp. 81-97
    • Anders, M.W.1
  • 2
    • 0025971827 scopus 로고
    • Glutathione S-transferases: Mechanism, structure, function
    • Armstrong R. (1991) Glutathione S-transferases: mechanism, structure, function. Chemical Research in Toxicology 4, 131-140.
    • (1991) Chemical Research in Toxicology , vol.4 , pp. 131-140
    • Armstrong, R.1
  • 3
    • 0023084762 scopus 로고
    • Enzyme catalyzed detoxication reactions: Mechanisms and stereochemistry
    • Armstrong R. N. (1987) Enzyme catalyzed detoxication reactions: Mechanisms and stereochemistry. CAC Critical Reviews in Biochemistry 22, 39-88.
    • (1987) CAC Critical Reviews in Biochemistry , vol.22 , pp. 39-88
    • Armstrong, R.N.1
  • 4
    • 0022483472 scopus 로고
    • Terpenoid transformation in mammals IV. Biotransformation of (+)-longifolene, (-)-caryophyllene, (-)-caryophyllene oxide (-)-cyclocolorenone, (+)-nootkatone, (-)-elemol, (-)-abietic acid, and (+)-dehydroabietic acid in rabbits
    • Asakawa Y., Ishida T., Toyota M. and Takemoto T. (1986) Terpenoid transformation in mammals IV. Biotransformation of (+)-longifolene, (-)-caryophyllene, (-)-caryophyllene oxide (-)-cyclocolorenone, (+)-nootkatone, (-)-elemol, (-)-abietic acid, and (+)-dehydroabietic acid in rabbits. Xenobiotica 16, 753-767.
    • (1986) Xenobiotica , vol.16 , pp. 753-767
    • Asakawa, Y.1    Ishida, T.2    Toyota, M.3    Takemoto, T.4
  • 5
    • 0011996068 scopus 로고
    • Determination of etheral oils from the urine by gas-liquid chromatography
    • Atzl G., Bertl M., Daxenbichler G. and Gleispach H. (1972) Determination of etheral oils from the urine by gas-liquid chromatography. Chromatographia 5, 250-255.
    • (1972) Chromatographia , vol.5 , pp. 250-255
    • Atzl, G.1    Bertl, M.2    Daxenbichler, G.3    Gleispach, H.4
  • 7
    • 0001521029 scopus 로고
    • Where we stand concerning the evaluation of flavouring substances from the viewpoint of health
    • Bar V. F. and Griepentrog F. (1967) "Where we stand concerning the evaluation of flavouring substances from the viewpoint of health." Medizin und Ernahrungsforschung 8, 244.
    • (1967) Medizin und Ernahrungsforschung , vol.8 , pp. 244
    • Bar, V.F.1    Griepentrog, F.2
  • 8
    • 0011924277 scopus 로고
    • Camphor
    • Edited by R. Wallace. Third Ed. Year Book Medical Publishers, Chicago, IL
    • Baselt R. C. and Cravey R. H. (1989) Camphor. In Disposition of Toxic Drugs and Chemicals in Man. Edited by R. Wallace. Third Ed. p. 123. Year Book Medical Publishers, Chicago, IL.
    • (1989) Disposition of Toxic Drugs and Chemicals in Man , pp. 123
    • Baselt, R.C.1    Cravey, R.H.2
  • 9
    • 0011983192 scopus 로고
    • Occupational carcinogens
    • Edited by G. D. Clayton & F. E. Clayton. 4th Ed. John Wiley & Sons, New York
    • Beliles R. P. and Schulz C. O. (1993) Occupational carcinogens. In Patty's Industrial Hygiene and Toxicology. Edited by G. D. Clayton & F. E. Clayton. 4th Ed. Vol. IIA. pp. 53-63. John Wiley & Sons, New York.
    • (1993) Patty's Industrial Hygiene and Toxicology , vol.2 A , pp. 53-63
    • Beliles, R.P.1    Schulz, C.O.2
  • 10
    • 0011988517 scopus 로고
    • On the dehydrogenation of exahydro-benzoic acid in the animal body
    • Bernhard K., Caflisch-Weill H. (1945) On the dehydrogenation of exahydro-benzoic acid in the animal body. Helvetica Chimica Acta 28, 1697-1707.
    • (1945) Helvetica Chimica Acta , vol.28 , pp. 1697-1707
    • Bernhard, K.1    Caflisch-Weill, H.2
  • 11
  • 13
    • 0001011289 scopus 로고
    • Alcohol dehydrogenase
    • Edited by W. B. Jakoby. Academic Press, New York
    • Bosron, W. F. and Ting-Kai L. (1980) Alcohol dehydrogenase. In Enzymatic Basis of Detoxication. Edited by W. B. Jakoby. Vol. I. pp. 231. Academic Press, New York.
    • (1980) Enzymatic Basis of Detoxication , vol.1 , pp. 231
    • Bosron, W.F.1    Ting-Kai, L.2
  • 14
    • 0021868683 scopus 로고
    • Heterogeneity of hepatic microsomal UDP-glucuronosyltransferase activities. Conjugations of phenolic and monoterpenoid aglycons in control and induced rats and guinea pigs
    • Boutin J. A., Thomassin J., Siest G. and Cartier A. (1985) Heterogeneity of hepatic microsomal UDP-glucuronosyltransferase activities. Conjugations of phenolic and monoterpenoid aglycons in control and induced rats and guinea pigs. Biochemical Pharmacology 34, 2235-2249.
    • (1985) Biochemical Pharmacology , vol.34 , pp. 2235-2249
    • Boutin, J.A.1    Thomassin, J.2    Siest, G.3    Cartier, A.4
  • 15
    • 0017749051 scopus 로고
    • The metabolism of cyclohexanecarboxylic acid in the isolated perfused rat liver
    • Brewster D., Jones R. S. and Parke D. V. (1977a) The metabolism of cyclohexanecarboxylic acid in the isolated perfused rat liver. Xenobiotica 7, 601-609.
    • (1977) Xenobiotica , vol.7 , pp. 601-609
    • Brewster, D.1    Jones, R.S.2    Parke, D.V.3
  • 16
    • 0017371203 scopus 로고
    • The metabolism of cyclohexanecarboxylic acid in the rat
    • Brewster D., Jones R. S. and Parke D. V. (1977b) The metabolism of cyclohexanecarboxylic acid in the rat. Biochemical Journal 164, 595-600.
    • (1977) Biochemical Journal , vol.164 , pp. 595-600
    • Brewster, D.1    Jones, R.S.2    Parke, D.V.3
  • 19
    • 0022648734 scopus 로고
    • Toxicology and carcinogenesis studies of isophorone in F344 rats and B6C3F1 mice
    • Bucher J., Huff J. and Kluwe W. (1986) Toxicology and carcinogenesis studies of isophorone in F344 rats and B6C3F1 mice. Toxicology 39, 207-219.
    • (1986) Toxicology , vol.39 , pp. 207-219
    • Bucher, J.1    Huff, J.2    Kluwe, W.3
  • 20
    • 0011957031 scopus 로고
    • Recent progress in the consideration of flavouring ingredients under the food additives amendment. 15. GRAS Substances
    • Burdock G. A., Wagner B. M., Smith R. L., Munro I. C. and Newberne P. M. (1990) Recent progress in the consideration of flavouring ingredients under the food additives amendment. 15. GRAS Substances. Food Technology 44, 78-86.
    • (1990) Food Technology , vol.44 , pp. 78-86
    • Burdock, G.A.1    Wagner, B.M.2    Smith, R.L.3    Munro, I.C.4    Newberne, P.M.5
  • 22
    • 0022653775 scopus 로고
    • Mutagen production by chlorination of methylated alpha, beta-unsaturated ketones
    • Cheh A. M. (1986) Mutagen production by chlorination of methylated alpha, beta-unsaturated ketones. Mutation Research 169, 1-9.
    • (1986) Mutation Research , vol.169 , pp. 1-9
    • Cheh, A.M.1
  • 23
    • 0011963961 scopus 로고
    • Edited by H. Maarse and C. A. Visscher. Centraal Instituut Voor Voedingsonderzoek TNO. Zeist, The Netherlands
    • CIVO-TNO (1989) Volatile Components in Food-Qualitative and Quantitative Data. 6th Ed. Vol. III. Edited by H. Maarse and C. A. Visscher. Centraal Instituut Voor Voedingsonderzoek TNO. Zeist, The Netherlands.
    • (1989) Volatile Components in Food-qualitative and Quantitative Data. 6th Ed. , vol.3
  • 25
    • 0000331076 scopus 로고
    • Glucuronic acid in the urine as a measure of the absorption of certain organic compounds
    • Deichmann W. and Thomas G. (1943) Glucuronic acid in the urine as a measure of the absorption of certain organic compounds. Journal of Industrial Hygene and Toxicology 25, 286-292.
    • (1943) Journal of Industrial Hygene and Toxicology , vol.25 , pp. 286-292
    • Deichmann, W.1    Thomas, G.2
  • 28
    • 0017986205 scopus 로고
    • Metabolic transformations of the trimethyl-3,5,5,cyclohexene-2, one-1 (isophorone)
    • Dutertre-Catella H., Nguyen P., Dang Q. and Truhaut R. (1978). Metabolic transformations of the trimethyl-3,5,5,cyclohexene-2, one-1 (isophorone). Toxicology European Research 1, 209-216.
    • (1978) Toxicology European Research , vol.1 , pp. 209-216
    • Dutertre-Catella, H.1    Nguyen, P.2    Dang, Q.3    Truhaut, R.4
  • 30
    • 0011989990 scopus 로고
    • Elliotl T. H., Parke D. V. and Williams R. T. (1943) Journal of Industrial Hygiene and Toxicology 25, 199; cited in Detoxication Mechanisms. The Metabolism and Detoxication of Drugs, Toxic Substances, and Other Organic Compounds (1959) Ediled by R. T. Williams. 2nd Ed. p. 117. Chapman and Hall, London.
    • (1943) Journal of Industrial Hygiene and Toxicology , vol.25 , pp. 199
    • Elliotl, T.H.1    Parke, D.V.2    Williams, R.T.3
  • 33
    • 0024998377 scopus 로고
    • Identification of cis-and trans-verbenol in human urine after occupational exposure to terpenes
    • Eriksson K. and Levin J. (1990) Identification of cis-and trans-verbenol in human urine after occupational exposure to terpenes. International Archives of Occupational and Environmental Health 62, 379-383.
    • (1990) International Archives of Occupational and Environmental Health , vol.62 , pp. 379-383
    • Eriksson, K.1    Levin, J.2
  • 34
    • 84908712637 scopus 로고
    • Toxicological evaluation of some flavouring substances and non-nutritive sweetening agents. Food and Agriculture Organisation of the United Nations World Health Organization
    • FAO (1967) Toxicological evaluation of some flavouring substances and non-nutritive sweetening agents. Food and Agriculture Organisation of the United Nations World Health Organization. FAO Nutrition Meetings Report Series.
    • (1967) FAO Nutrition Meetings Report Series
  • 35
  • 36
    • 4244183386 scopus 로고
    • Sludies on β-glucuronidase. III. The increase in β-glucuronidase activity of mammalian tissues induced by feeding glucuronidogenic substances
    • Fishman W. H. (1940) Sludies on β-glucuronidase. III. The increase in β-glucuronidase activity of mammalian tissues induced by feeding glucuronidogenic substances. Journal of Biological Chemistry 136, 229-236.
    • (1940) Journal of Biological Chemistry , vol.136 , pp. 229-236
    • Fishman, W.H.1
  • 37
    • 0003900130 scopus 로고
    • Priority-based Assessment of Food additives (PAFA) Database
    • Food and Drug Administration, Washington, DC
    • FDA (1993) Priority-based Assessment of Food additives (PAFA) Database, p. 58. Center for Food Safety and Applied Nutrition. Food and Drug Administration, Washington, DC.
    • (1993) Center for Food Safety and Applied Nutrition , pp. 58
  • 41
    • 0020428204 scopus 로고
    • Hepatotoxicity and pulmonary toxicity of pennyroyal oil and its constituenls terpenes in the mouse
    • Gordon W. P., Forte A. J., McMurtry R. J., Gal. H. and Nelson S. D. (1982) Hepatotoxicity and pulmonary toxicity of pennyroyal oil and its constituenls terpenes in the mouse. Toxicology and Applied Pharmacology 65, 413-424.
    • (1982) Toxicology and Applied Pharmacology , vol.65 , pp. 413-424
    • Gordon, W.P.1    Forte, A.J.2    McMurtry, R.J.3    Gal, H.4    Nelson, S.D.5
  • 44
    • 0024401672 scopus 로고
    • Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro III: Results with 27 chemicals
    • Gulati D. K., Witt K., Andersen B., Zeiger E. and Shelby M. D. (1989) Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro III: results with 27 chemicals. Environmental and Molecular Mutagenesis 13, 133-193.
    • (1989) Environmental and Molecular Mutagenesis , vol.13 , pp. 133-193
    • Gulati, D.K.1    Witt, K.2    Andersen, B.3    Zeiger, E.4    Shelby, M.D.5
  • 45
    • 0011954665 scopus 로고
    • Plant known for centuries still causes problems today
    • Gunby P. (1979) Plant known for centuries still causes problems today. Journal of the American Medical Association 243, 1355-1366.
    • (1979) Journal of the American Medical Association , vol.243 , pp. 1355-1366
    • Gunby, P.1
  • 46
    • 0027965512 scopus 로고
    • Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene
    • Haag J. D. and Gould M. N. (1994) Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene. Cancer Chemotherapy and Pharmacology 34, 477-483.
    • (1994) Cancer Chemotherapy and Pharmacology , vol.34 , pp. 477-483
    • Haag, J.D.1    Gould, M.N.2
  • 48
    • 0011991804 scopus 로고
    • Concerning the behavior of alicyclic compounds with glucuronic acid in organisms
    • Hamalainen J. (1912) Concerning the behavior of alicyclic compounds with glucuronic acid in organisms. Skandinavisches Archives für Physiologie 27, 141-226.
    • (1912) Skandinavisches Archives für Physiologie , vol.27 , pp. 141-226
    • Hamalainen, J.1
  • 49
    • 0000747053 scopus 로고
    • Carboxylesterases and amidases
    • Edited by W. B. Jakoby. 2nd Ed. Academic Press, New York
    • Heymann E. (1980) Carboxylesterases and amidases. In Enzymatic Basis of Detoxication. Edited by W. B. Jakoby. 2nd Ed. pp. 291-323. Academic Press, New York.
    • (1980) Enzymatic Basis of Detoxication , pp. 291-323
    • Heymann, E.1
  • 51
    • 0029055553 scopus 로고
    • Induction of hepatic P450s in rat by essential wood and leaf oils
    • Hiroi T., Miyazaki Y., Kobayashi Y., Imaoka S. and Funae Y. (1995) Induction of hepatic P450s in rat by essential wood and leaf oils. Xenobiotica 5, 457-467.
    • (1995) Xenobiotica , vol.5 , pp. 457-467
    • Hiroi, T.1    Miyazaki, Y.2    Kobayashi, Y.3    Imaoka, S.4    Funae, Y.5
  • 53
    • 0014843496 scopus 로고
    • Metabolism of β-ionone. Isolation, characterization and identification of the metabolites in the urine of rabbits
    • Ide H. and Toki S. (1970) Metabolism of β-ionone. Isolation, characterization and identification of the metabolites in the urine of rabbits. Biochemical Journal 119, 281-287.
    • (1970) Biochemical Journal , vol.119 , pp. 281-287
    • Ide, H.1    Toki, S.2
  • 54
    • 0019452187 scopus 로고
    • Terpenoids biotransformation in mammals III: Biotransformation of α-pinene. β-pinene, pinane, 3-carene, carane, myracene, and p-cymene in rabbits
    • Ishida T., Asakawa Y., Takemoto T. and Aratani T. (1981) Terpenoids biotransformation in mammals III: biotransformation of α-pinene. β-pinene, pinane, 3-carene, carane, myracene, and p-cymene in rabbits. Journal of Pharmaceutical Science 70, 406-415.
    • (1981) Journal of Pharmaceutical Science , vol.70 , pp. 406-415
    • Ishida, T.1    Asakawa, Y.2    Takemoto, T.3    Aratani, T.4
  • 55
    • 0024397335 scopus 로고
    • Terpenoid biotransformation in mammals. V. Metabolism of (+)-citronellal, (+)-7-hydroxycitronellal, citral, (-)-perillaldehyde, (-)-myrtenal, cuminalehyde, thujone, and (+)-carvone in rabbits
    • Ishida T., Toyota M. and Asakawa Y. (1989) Terpenoid biotransformation in mammals. V. Metabolism of (+)-citronellal, (+)-7-hydroxycitronellal, citral, (-)-perillaldehyde, (-)-myrtenal, cuminalehyde, thujone, and (+)-carvone in rabbits. Xenobiotica 19, 843-855.
    • (1989) Xenobiotica , vol.19 , pp. 843-855
    • Ishida, T.1    Toyota, M.2    Asakawa, Y.3
  • 56
    • 0015158052 scopus 로고
    • The metabolism of alicyclic ketones in the rabbit and rat
    • James S. P. and Waring R. H. (1971). The metabolism of alicyclic ketones in the rabbit and rat. Xenobiotica 1, 573-580.
    • (1971) Xenobiotica , vol.1 , pp. 573-580
    • James, S.P.1    Waring, R.H.2
  • 57
    • 0025236401 scopus 로고
    • Determination of menthol and menthol glucuronide in human urine by gas chromatography using an enzyme-sensitive internal standard and flame ionization detection
    • Kaffenberger R. M. and Doyle M. J. (1990) Determination of menthol and menthol glucuronide in human urine by gas chromatography using an enzyme-sensitive internal standard and flame ionization detection. Journal of Chromatography 527, 59-66.
    • (1990) Journal of Chromatography , vol.527 , pp. 59-66
    • Kaffenberger, R.M.1    Doyle, M.J.2
  • 60
    • 0026020324 scopus 로고
    • Plasma pharmacokinetics and metabolism of 13-cis-and alltrans-Ktinoic acid in the cynomolgus monkey and the identification of 13-cis-and all-trans-retinoyl-β-glucuronides. A comparison to one human case study with isotretinoin
    • Kraft J. C., Slikker J. W., Jr, Bailey J. R., Roberts L. G., Fischer B., Wittfoht W. and Nau H. (1991) Plasma pharmacokinetics and metabolism of 13-cis-and alltrans-Ktinoic acid in the cynomolgus monkey and the identification of 13-cis-and all-trans-retinoyl-β-glucuronides. A comparison to one human case study with isotretinoin. Drug Metabolism and Disposition 19, 317-324.
    • (1991) Drug Metabolism and Disposition , vol.19 , pp. 317-324
    • Kraft, J.C.1    Slikker J.W., Jr.2    Bailey, J.R.3    Roberts, L.G.4    Fischer, B.5    Wittfoht, W.6    Nau, H.7
  • 63
    • 0015603413 scopus 로고
    • Mammalian metabolism of terpenoids. I. Reduction and hydroxylation of camphor and related compounds
    • Leibman K. C. and Ortiz E. (1973) Mammalian metabolism of terpenoids. I. Reduction and hydroxylation of camphor and related compounds. Drug Metabolism and Disposition 1, 543-551.
    • (1973) Drug Metabolism and Disposition , vol.1 , pp. 543-551
    • Leibman, K.C.1    Ortiz, E.2
  • 64
    • 0024453882 scopus 로고
    • Metabolic activation of (R)-(+)-pulegone to a reactive enonal that covalently binds to mouse liver proteins
    • McClanahan R. H., Thomassen D., Slattery J. T. and Nelson S. D. (1989) Metabolic activation of (R)-(+)-pulegone to a reactive enonal that covalently binds to mouse liver proteins. Chemical Research in Toxicology 2, 349-355.
    • (1989) Chemical Research in Toxicology , vol.2 , pp. 349-355
    • McClanahan, R.H.1    Thomassen, D.2    Slattery, J.T.3    Nelson, S.D.4
  • 67
    • 0022912498 scopus 로고
    • Short-term toxicity in rats dosed with methone
    • Madsen C., Wurtzen G. and Carstensen J. (1986) Short-term toxicity in rats dosed with methone. Toxicology Letters 32, 147-152.
    • (1986) Toxicology Letters , vol.32 , pp. 147-152
    • Madsen, C.1    Wurtzen, G.2    Carstensen, J.3
  • 69
    • 0025565951 scopus 로고
    • Biotransformations of R-(+)-pulegone and menthofuran in vitro: Chemical basis for toxicity
    • Madyastha K. M. and Raj C. P. (1990) Biotransformations of R-(+)-pulegone and menthofuran in vitro: chemical basis for toxicity. Biochemical and Biophysical Research Communications 3, 1086-1092.
    • (1990) Biochemical and Biophysical Research Communications , vol.3 , pp. 1086-1092
    • Madyastha, K.M.1    Raj, C.P.2
  • 70
    • 0027247503 scopus 로고
    • Studies on the metabolism of a monoterpene ketone, R-( + )-pulegone a hepatotoxin in rat: Isolation and characterization of new metabolites
    • Madyastha K. M. and Raj. C. P. (1993) Studies on the metabolism of a monoterpene ketone, R-( + )-pulegone a hepatotoxin in rat: isolation and characterization of new metabolites. Xenobiotica 23, 509-518.
    • (1993) Xenobiotica , vol.23 , pp. 509-518
    • Madyastha, K.M.1    Raj, C.P.2
  • 72
    • 0023802563 scopus 로고
    • Biotransformations of α-terpineol in the rat: Its effects on the liver microsomal cytochrome P-450 system
    • Madyastha K. M. and Srivatsan V. (1988b) Biotransformations of α-terpineol in the rat: its effects on the liver microsomal cytochrome P-450 system. Bulletin of Environmental Contamination and Toxicology 41, 17-25.
    • (1988) Bulletin of Environmental Contamination and Toxicology , vol.41 , pp. 17-25
    • Madyastha, K.M.1    Srivatsan, V.2
  • 73
    • 85047694480 scopus 로고
    • Interpretation of rodent hepatocellular proliferative alterations and hepatocellular tumors in chemical safety assessment
    • Maronpot R. R. and Boorman G. A. (1982) Interpretation of rodent hepatocellular proliferative alterations and hepatocellular tumors in chemical safety assessment. Toxicologie Pathology 10, 71-80.
    • (1982) Toxicologie Pathology , vol.10 , pp. 71-80
    • Maronpot, R.R.1    Boorman, G.A.2
  • 74
    • 0023083990 scopus 로고
    • Liver lesions in B6C3F1 mice: The National Toxicology Program, Experience, and Position
    • Maronpot R. R., Haseman J. K., Boorman G. A., Eustis S. E., Rao G. N. and Huff J. E. (1987) Liver lesions in B6C3F1 mice: the National Toxicology Program, Experience, and Position. Archives of Toxicology (Supplement) 10, 10-26.
    • (1987) Archives of Toxicology , vol.10 , Issue.SUPPL. , pp. 10-26
    • Maronpot, R.R.1    Haseman, J.K.2    Boorman, G.A.3    Eustis, S.E.4    Rao, G.N.5    Huff, J.E.6
  • 75
    • 0024399798 scopus 로고
    • Toxicological evaluation of peppermint oil in rodents and dogs
    • Mengs U. and Stotzem C. D. (1989) Toxicological evaluation of peppermint oil in rodents and dogs. Medical Science Research 17, 499-500.
    • (1989) Medical Science Research , vol.17 , pp. 499-500
    • Mengs, U.1    Stotzem, C.D.2
  • 79
    • 0024555267 scopus 로고
    • Hepatotoxicity of pulegone in rats: Its effects on microsomal enzymes, in vivo
    • Moorthy B., Madyastha P. and Madyastha M. (1989) Hepatotoxicity of pulegone in rats: its effects on microsomal enzymes, in vivo. Toxicology 55, 327-337.
    • (1989) Toxicology , vol.55 , pp. 327-337
    • Moorthy, B.1    Madyastha, P.2    Madyastha, M.3
  • 80
    • 0026071931 scopus 로고
    • Destruction of rat liver microsomal cytochrome P-450 in vitro by a monoterpene ketone, pulegone - A hepatotoxin
    • Moorthy B., Madyastha P. and Madyastha K. M. (1991) Destruction of rat liver microsomal cytochrome P-450 in vitro by a monoterpene ketone, pulegone - a hepatotoxin. Indian Journal of Chemistry 30, 138-146.
    • (1991) Indian Journal of Chemistry , vol.30 , pp. 138-146
    • Moorthy, B.1    Madyastha, P.2    Madyastha, K.M.3
  • 82
    • 0004148842 scopus 로고
    • National Academy of Sciences, Washington, DC
    • NAS (1970) Evaluating the safety of food chemicals. National Academy of Sciences, Washington, DC.
    • (1970) Evaluating the Safety of Food Chemicals
  • 83
    • 0011991811 scopus 로고
    • National Academy of Sciences, Washington, DC
    • NAS (1975) Evaluating the safety of food chemicals. National Academy of Sciences, Washington, DC.
    • (1975) Evaluating the Safety of Food Chemicals
  • 84
    • 0004148838 scopus 로고
    • National Academy of Sciences, Washington, DC
    • NAS (1982) Evaluating the safety of food chemicals. National Academy of Sciences, Washington, DC.
    • (1982) Evaluating the Safety of Food Chemicals
  • 85
    • 0004148840 scopus 로고
    • National Academy of Sciences, Washington, DC
    • NAS (1987) Evaluating the safety of food chemicals. National Academy of Sciences, Washington, DC.
    • (1987) Evaluating the Safety of Food Chemicals
  • 86
    • 0011988521 scopus 로고
    • National Academy of Sciences-National Research Council, Washington, DC
    • NAS/NRC (1976) Evaluating the safety of food chemicals. National Academy of Sciences-National Research Council, Washington, DC.
    • (1976) Evaluating the Safety of Food Chemicals
  • 87
    • 0011923945 scopus 로고
    • National Cancer Institute. US Department of Health, Education and Welfare. National Technical Report Series No. 98
    • NCI (1978) Bioassay of dl-menthol for possible carcinogenicity. National Cancer Institute. US Department of Health, Education and Welfare. National Technical Report Series No. 98.
    • (1978) Bioassay of Dl-menthol for Possible Carcinogenicity
  • 88
    • 0026672930 scopus 로고
    • Investigations of mechanisms of reactive metabolite formation from (R)-( + )-pulegone
    • Nelson S. D., McClanahan R. H., Thomassen D., Gordon W. P. and Knebel N. (1992) Investigations of mechanisms of reactive metabolite formation from (R)-( + )-pulegone. Xenobiotica 22, 1157-1164.
    • (1992) Xenobiotica , vol.22 , pp. 1157-1164
    • Nelson, S.D.1    McClanahan, R.H.2    Thomassen, D.3    Gordon, W.P.4    Knebel, N.5
  • 89
    • 0001267981 scopus 로고
    • Concerning the pairing of glucuronic acid with materials if the aliphatic series
    • Neubeuer O. (1901) Concerning the pairing of glucuronic acid with materials if the aliphatic series. Archives of Experimental Pathology and Pharmacology 46, 133-145.
    • (1901) Archives of Experimental Pathology and Pharmacology , vol.46 , pp. 133-145
    • Neubeuer, O.1
  • 90
    • 0023176478 scopus 로고
    • Identification of urinary and microsomal metabolites of geranylgeranylacetone in rats
    • Nishizawa, Y., Abe S., Yamada K., Nakamura T., Yamatsu I. and Kinoshita K. (1987) Identification of urinary and microsomal metabolites of geranylgeranylacetone in rats. Xenobiotica 17, 575-584.
    • (1987) Xenobiotica , vol.17 , pp. 575-584
    • Nishizawa, Y.1    Abe, S.2    Yamada, K.3    Nakamura, T.4    Yamatsu, I.5    Kinoshita, K.6
  • 91
    • 0347228820 scopus 로고
    • National Toxicology Program. NTP-TR-291; NIH Publication No. 86-2547. Department of Health and Human Services, Research Triangle Park, NC
    • NTP (1986) Toxicology and carcinogenesis studies of isophorone in F344/N rats and B6C3F1 mice (gavage studies). National Toxicology Program. NTP-TR-291; NIH Publication No. 86-2547. Department of Health and Human Services, Research Triangle Park, NC.
    • (1986) Toxicology and Carcinogenesis Studies of Isophorone in F344/n Rats and B6c3f1 Mice (Gavage Studies)
  • 92
    • 0011923040 scopus 로고
    • National Toxicology Program. NTP TR 381. National Institute of Environmental Health Sciences, National Institute of Health, Public Health Service, Department of Health and Human Services, Research Triangle Park, NC
    • NTP (1990) National Toxicology Program Technical Report on the toxicology and carcinogenesis studies of d-carvone in B6C3F1 Mice (gavage studies). National Toxicology Program. NTP TR 381. National Institute of Environmental Health Sciences, National Institute of Health, Public Health Service, Department of Health and Human Services, Research Triangle Park, NC.
    • (1990) National Toxicology Program Technical Report on the Toxicology and Carcinogenesis Studies of D-carvone in B6c3f1 Mice (Gavage Studies)
  • 99
    • 0025217788 scopus 로고
    • A comparison of male rat and human urinary proteins: Implications for human resistance to hyaline droplet nephropathy
    • Olson M. J., Johnson J. T. and Reidy C. A. (1990) A comparison of male rat and human urinary proteins: implications for human resistance to hyaline droplet nephropathy. Toxicology and Applied Pharmacology 102, 524-536.
    • (1990) Toxicology and Applied Pharmacology , vol.102 , pp. 524-536
    • Olson, M.J.1    Johnson, J.T.2    Reidy, C.A.3
  • 101
    • 0017712377 scopus 로고
    • Criteria employed by the Expert Panel of the FEMA for the GRAS evaluation of flavour ingredients
    • Oser B. L. and Hall R. L. (1977) Criteria employed by the Expert Panel of the FEMA for the GRAS evaluation of flavour ingredients. Food and Cosmetics Toxicology 15, 457-466.
    • (1977) Food and Cosmetics Toxicology , vol.15 , pp. 457-466
    • Oser, B.L.1    Hall, R.L.2
  • 102
    • 0011958341 scopus 로고
    • FEMA Expert Panel: 30 years of safety evaluation for the flavour industry
    • Oser B. L. and Ford R. A. (1991) FEMA Expert Panel: 30 years of safety evaluation for the flavour industry. Food Technology 45, 84-97.
    • (1991) Food Technology , vol.45 , pp. 84-97
    • Oser, B.L.1    Ford, R.A.2
  • 103
    • 17444433172 scopus 로고
    • The effects of some terpenoids and other dietary anutrients on hepatic drug-metabolizing enzymes
    • Parke D. V. and Rahman H. (1969) The effects of some terpenoids and other dietary anutrients on hepatic drug-metabolizing enzymes. Biochemical Journal 113, 124.
    • (1969) Biochemical Journal , vol.113 , pp. 124
    • Parke, D.V.1    Rahman, H.2
  • 104
    • 0025786629 scopus 로고
    • Metabolism and disposition of cyclohexanone oxime in male F-344 rats
    • Farmer D. and Burka L. T. (1991) Metabolism and disposition of cyclohexanone oxime in male F-344 rats. Drug Metabolism and Disposition 19, 1101-1107.
    • (1991) Drug Metabolism and Disposition , vol.19 , pp. 1101-1107
    • Farmer, D.1    Burka, L.T.2
  • 107
    • 0011988523 scopus 로고
    • 3rd Revised Ed. John Wiley & Sons, New York
    • Pohl J. (1925) Zentralblatt für Gewerbehygiene und Unfallverhuetlung 12, 91; cited in Patty's Industrial Hygiene and Toxicology. 1982. 3rd Revised Ed. Vol. IIC. p. 4648. John Wiley & Sons, New York.
    • (1982) Patty's Industrial Hygiene and Toxicology , vol.2 C , pp. 4648
  • 109
    • 0014545649 scopus 로고
    • Summaries of toxicological data. Toxicological tests on flavouring matters
    • Posternak J. M., Under A. and Vodoz C. A. (1969) Summaries of toxicological data. Toxicological tests on flavouring matters. Food and Cosmetics Toxicology 7, 405-407.
    • (1969) Food and Cosmetics Toxicology , vol.7 , pp. 405-407
    • Posternak, J.M.1    Under, A.2    Vodoz, C.A.3
  • 110
    • 0016708770 scopus 로고
    • Toxicology tests on flavouring matters. II. Pyrazines and other compounds
    • Posternak J. M. and Vodoz C. A. (1975) Toxicology tests on flavouring matters. II. Pyrazines and other compounds. Food and Cosmetics Toxicology 13, 487-490.
    • (1975) Food and Cosmetics Toxicology , vol.13 , pp. 487-490
    • Posternak, J.M.1    Vodoz, C.A.2
  • 111
    • 84981840472 scopus 로고
    • Uber die biochemische oxydation von β-ionon im tierkorper
    • Prelog V. and Meier H. L. (1950) Uber die biochemische oxydation von β-ionon im tierkorper. Helvetica Chimica Acta 33, 1276-1284.
    • (1950) Helvetica Chimica Acta , vol.33 , pp. 1276-1284
    • Prelog, V.1    Meier, H.L.2
  • 112
    • 84981837750 scopus 로고
    • Uber die biochemische oxydation von α-ionon im tierkorper
    • Prelog V. and Wursch J. (1951) Uber die biochemische oxydation von α-ionon im tierkorper. Helvetica Chimica Acta 34, 859-861.
    • (1951) Helvetica Chimica Acta , vol.34 , pp. 859-861
    • Prelog, V.1    Wursch, J.2
  • 113
    • 0011952404 scopus 로고
    • The biochemistry and physiology of glucuronic acid. IV. a) The occurrence of conjugated glucuronic acids in the animal body, b) Observations on the conjugation of d-and l-borneol
    • Pryde J. and Williams R. T. (1934) The biochemistry and physiology of glucuronic acid. IV. a) The occurrence of conjugated glucuronic acids in the animal body, b) Observations on the conjugation of d-and l-borneol. Biochemical Journal 28, 131-135.
    • (1934) Biochemical Journal , vol.28 , pp. 131-135
    • Pryde, J.1    Williams, R.T.2
  • 114
    • 0011958177 scopus 로고
    • The synthesis of menthol glucuronide acid in the rabbit
    • Quick A. J. (1924) The synthesis of menthol glucuronide acid in the rabbit. Journal of Biological Chemistry 61, 679-683.
    • (1924) Journal of Biological Chemistry , vol.61 , pp. 679-683
    • Quick, A.J.1
  • 115
    • 0011994609 scopus 로고
    • The preparation of borneol glycuronic acid and glycuronic acid
    • Quick A. J. (1927) The preparation of borneol glycuronic acid and glycuronic acid. Journal of Biological Chemistry 74, 331-341.
    • (1927) Journal of Biological Chemistry , vol.74 , pp. 331-341
    • Quick, A.J.1
  • 116
    • 0012007319 scopus 로고
    • Quantitative studies of β-oxidation. IV. The metabolism of conjugated glucuronic acids
    • Quick A. J. (1928) Quantitative studies of β-oxidation. IV. The metabolism of conjugated glucuronic acids. Journal of Biological Chemistry 80, 535-541.
    • (1928) Journal of Biological Chemistry , vol.80 , pp. 535-541
    • Quick, A.J.1
  • 117
    • 84908739922 scopus 로고
    • Decomposition of fenchone in the animal organism
    • Reinhartz F. and Zanke W. (1936) Decomposition of fenchone in the animal organism. Berichte 69B, 2259-2262.
    • (1936) Berichte , vol.69 B , pp. 2259-2262
    • Reinhartz, F.1    Zanke, W.2
  • 119
    • 0011951988 scopus 로고
    • The biological oxidation of fenchone
    • Rimini E. (1901) The biological oxidation of fenchone. Rendiconti 10, 244-249.
    • (1901) Rendiconti , vol.10 , pp. 244-249
    • Rimini, E.1
  • 120
    • 0014532099 scopus 로고
    • Metabolism of camphors and related compounds
    • Robertson J. S. and Hussain M. (1969) Metabolism of camphors and related compounds. Biochemical Journal 113, 57-65.
    • (1969) Biochemical Journal , vol.113 , pp. 57-65
    • Robertson, J.S.1    Hussain, M.2
  • 121
    • 0011923363 scopus 로고
    • Sasaki Y. (1917) Acta Schol. Med. Univ. Imp. Kioto, 1, 413; cited in Patty's Industrial Hvgiene and Toxicology. 1982. 3rd Revised Ed. Vol. IIC. p. 4648. John Wiley & Sons, New York.
    • (1917) Acta Schol. Med. Univ. Imp. Kioto , vol.1 , pp. 413
    • Sasaki, Y.1
  • 122
    • 0011988523 scopus 로고
    • 3rd Revised Ed. John Wiley & Sons, New York
    • Sasaki Y. (1917) Acta Schol. Med. Univ. Imp. Kioto, 1, 413; cited in Patty's Industrial Hygiene and Toxicology. 1982. 3rd Revised Ed. Vol. IIC. p. 4648. John Wiley & Sons, New York.
    • (1982) Patty's Industrial Hygiene and Toxicology , vol.2 C , pp. 4648
  • 124
    • 0011954325 scopus 로고
    • Action of some synthetic substances on animal organism
    • Shillinger J. I. (1950) Action of some synthetic substances on animal organism. Gigiena i Sanitariya 3, 37-41.
    • (1950) Gigiena I Sanitariya , vol.3 , pp. 37-41
    • Shillinger, J.I.1
  • 126
    • 0019757296 scopus 로고
    • Metabolism and nutritional significance of carotenoids
    • Simpson K. L. and Chichester C. O. (1981) Metabolism and nutritional significance of carotenoids. Annual Review of Nutrition 1, 351-374.
    • (1981) Annual Review of Nutrition , vol.1 , pp. 351-374
    • Simpson, K.L.1    Chichester, C.O.2
  • 127
    • 0012007320 scopus 로고
    • On the toxicity and compatibility of essential oils
    • Skramlik E. V. (1959) On the toxicity and compatibility of essential oils. Pharmazie 14, 435-445.
    • (1959) Pharmazie , vol.14 , pp. 435-445
    • Skramlik, E.V.1
  • 128
    • 0000160802 scopus 로고
    • Recent progress in consideration of flavouring ingredients under the Food Additives Amendment. 16. GRAS Substances
    • Smith R. L. and Ford R. A. (1993) Recent progress in consideration of flavouring ingredients under the Food Additives Amendment. 16. GRAS Substances. Food Technology 47, 104-117.
    • (1993) Food Technology , vol.47 , pp. 104-117
    • Smith, R.L.1    Ford, R.A.2
  • 129
    • 0022410028 scopus 로고
    • The consumption ratio of flavouring materials: A mechanism for setting priorities for safety evaluation
    • Stofberg J. and Kirschman J. C. (1985) The consumption ratio of flavouring materials: A mechanism for setting priorities for safety evaluation. Food and Chemical Toxicology 23, 857-860.
    • (1985) Food and Chemical Toxicology , vol.23 , pp. 857-860
    • Stofberg, J.1    Kirschman, J.C.2
  • 130
    • 0002460382 scopus 로고
    • Consumption ratio and food predominance of flavouring materials
    • Stofberg J. and Grundschober F. (1987) Consumption ratio and food predominance of flavouring materials. Perfumer and Flavourist 12, 27.
    • (1987) Perfumer and Flavourist , vol.12 , pp. 27
    • Stofberg, J.1    Grundschober, F.2
  • 131
  • 136
    • 0023836650 scopus 로고
    • Contribution of menthofuran to the hepatotoxicity of pulegone: Assessment based on matched area under the curve and on matched time course
    • Thomassen D., Slattery J. T. and Nelson S. D.(1988) Contribution of menthofuran to the hepatotoxicity of pulegone: assessment based on matched area under the curve and on matched time course. Journal of Pharmacology and Experimental Therapeutics 224, 825.
    • (1988) Journal of Pharmacology and Experimental Therapeutics , vol.224 , pp. 825
    • Thomassen, D.1    Slattery, J.T.2    Nelson, S.D.3
  • 140
    • 0021018027 scopus 로고
    • Short-term toxicity study in rats dosed with pulegone and menthol
    • Thorup I., Wuertzen J., Carstensen J. and Olsen P. (1983a) Short-term toxicity study in rats dosed with pulegone and menthol. Toxicology Letters 19, 207-210.
    • (1983) Toxicology Letters , vol.19 , pp. 207-210
    • Thorup, I.1    Wuertzen, J.2    Carstensen, J.3    Olsen, P.4
  • 141
    • 0021087280 scopus 로고
    • Short-term toxicity study in rats dosed with peppermint oil
    • Thorup I., Wuertzen J., Carstensen J. and Olsen P. (1983b) Short-term toxicity study in rats dosed with peppermint oil. Toxicology Letters 19, 211-215.
    • (1983) Toxicology Letters , vol.19 , pp. 211-215
    • Thorup, I.1    Wuertzen, J.2    Carstensen, J.3    Olsen, P.4
  • 143
    • 0011988523 scopus 로고
    • 3rd Revised Ed. John Wiley & Sons, New York
    • Treon J. F., Crutchfield W. E., Jr and Kitzmiller K. V. (1943) Journal of Industrial Hygiene and Toxicology 25, 199; cited in Patty's Industrial Hygiene and Toxicology. 1982. 3rd Revised Ed. Vol. IIC. p. 4648. John Wiley & Sons, New York.
    • (1982) Patty's Industrial Hygiene and Toxicology , vol.2 C , pp. 4648
  • 145
    • 0025173806 scopus 로고
    • Human biliary metabolites of isotretinoin: Identification, quantification, synthesis and biological activity
    • Vane F. M., Bugge C. J. L., Rodriguez L. C., Rosenberger M. and Doran T. I. (1990) Human biliary metabolites of isotretinoin: identification, quantification, synthesis and biological activity. Xenobiolica 20, 193-207.
    • (1990) Xenobiolica , vol.20 , pp. 193-207
    • Vane, F.M.1    Bugge, C.J.L.2    Rodriguez, L.C.3    Rosenberger, M.4    Doran, T.I.5
  • 146
    • 0021811377 scopus 로고
    • Further studies of ram-sobrerol metabolism: Rat, dog, and human urine
    • Ventura P., Schiavi M., Serafini S. and Selva S. (1985) Further studies of (ram-sobrerol metabolism: rat, dog, and human urine. Xenobiotica 15, 317-325.
    • (1985) Xenobiotica , vol.15 , pp. 317-325
    • Ventura, P.1    Schiavi, M.2    Serafini, S.3    Selva, S.4
  • 150
    • 0025098769 scopus 로고
    • Chemical synthesis of dual radiolabelled cyclandelate and its metabolism in rat hepatocytes and mouse J774 cells
    • White D. A., Heffron A., Miciak B., Middleton B., Knights S. and Knights D. (1990) Chemical synthesis of dual radiolabelled cyclandelate and its metabolism in rat hepatocytes and mouse J774 cells. Xenobiotica 20, 71.
    • (1990) Xenobiotica , vol.20 , pp. 71
    • White, D.A.1    Heffron, A.2    Miciak, B.3    Middleton, B.4    Knights, S.5    Knights, D.6
  • 151
    • 0011980792 scopus 로고
    • Studies in detoxication. II. a) The conjugation of isomeric 3-menthanols with glucuronic acid and the asymmetric conjugation of dl-menthol and dl-menthol in the rabbit. b) d-iso-Menthylglucuronide, a new conjugated glucuronic acid
    • Williams R. T. (1938) Studies in detoxication. II. a) The conjugation of isomeric 3-menthanols with glucuronic acid and the asymmetric conjugation of dl-menthol and dl-menthol in the rabbit. b) d-iso-Menthylglucuronide, a new conjugated glucuronic acid. Biochemical Journal 32, 1849-1855.
    • (1938) Biochemical Journal , vol.32 , pp. 1849-1855
    • Williams, R.T.1
  • 152
    • 0011988524 scopus 로고
    • Studies in detoxication. III. The use of the glucuronic acid detoxication mechanism of the rabbit for the resolution of dl-menthol
    • Williams R. T. (1939) Studies in detoxication. III. The use of the glucuronic acid detoxication mechanism of the rabbit for the resolution of dl-menthol. Biochemical Journal 33, 1519-1524.
    • (1939) Biochemical Journal , vol.33 , pp. 1519-1524
    • Williams, R.T.1
  • 153
    • 0011924136 scopus 로고
    • Studies in detoxication. 7. The biological reduction of l-Menthone to d-neomenthol and of d-isomenthone to d-isomenthol in the rabbit. The conjugation of d-neomenthol with glucuronic acid
    • Williams R. T. (1940) Studies in detoxication. 7. The biological reduction of l-Menthone to d-neomenthol and of d-isomenthone to d-isomenthol in the rabbit. The conjugation of d-neomenthol with glucuronic acid. Biochemical Journal 34, 690-697.
    • (1940) Biochemical Journal , vol.34 , pp. 690-697
    • Williams, R.T.1
  • 155
    • 0025800243 scopus 로고
    • GRAS evaluation of flavour ingredients by the Expert Panel of FEMA
    • Woods L. and Doull J. (1991) GRAS evaluation of flavour ingredients by the Expert Panel of FEMA. Regulatory Toxicology and Pharmacology 14, 48.
    • (1991) Regulatory Toxicology and Pharmacology , vol.14 , pp. 48
    • Woods, L.1    Doull, J.2


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