Is HP1 an RNA detector that functions both in repression and activation?

Journal of Cell Biology

Volumn 161, Issue 4, 2003, Pages 671-672

  Kellum, Rebecca ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME PROTEIN; HETEROCHROMATIN PROTEIN 1; NUCLEOPROTEIN; UNCLASSIFIED DRUG;

CELL CYCLE; CHROMATIN; EUCHROMATIN; GENE SILENCING; GENETIC ANALYSIS; HETEROCHROMATIN; HUMAN; IMMUNOHISTOCHEMISTRY; INTERPHASE; ISOTOPE LABELING; MUTANT; NONHUMAN; POLYTENE CHROMOSOME; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SEQUENCE HOMOLOGY; YEAST;

ANIMALS; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; GENE EXPRESSION REGULATION; HUMANS; REPRESSOR PROTEINS; RNA; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

SCHIZOSACCHAROMYCES POMBE;

EID: 0037684838     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200304145     Document Type: Review

References (19)

1. Akhtar, A., D. Zink, and P.B. Becker. 2000. Chromodomains are protein-RNA interaction modules. Nature. 407:405-409.
2. Bannister, A.J., P. Zegerman, J.F. Partridge, E.A. Miska, J.O. Thomas, R.C. Allshire, and T. Kouzarides. 2001. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature. 410:120-124.
3. Cryderman, D.E., H. Tang, C. Bell, D.S. Gilmour, and L.L. Wallrath. 1999. Heterochromatic silencing of Drosophila heat shock genes acts at the level of promoter potentiation. Nucleic Acids Res. 27:3364-3370.
4. Eissenberg, J.C., and S.C.R. Elgin. 2000. The HP1 protein family: getting a grip on chromatin. Curr. Opin. Genet. Dev. 10:204-210.
5. Grigliatti, T. 1991. Position effect variegation - An assay for nonhistone chromosomal proteins and chromatin assembly and modifying factors. Methods Cell Biol. 35:587-627.
6. Heitz, E. 1928. Das Heterochromatin der Moose. Jahrbücher für Wissenschaftliche Botanik. 69:762-818.
7. Hearn, M.G., A. Hedrick, T.A. Grigliatti, and B.T. Wakimoto. 1991. The effect of modifiers of position-effect variegation on the variegation of heterochromatic genes of Drosophila melanogaster. Genetics. 128:785-797.
8. Hwang, K.-K., J.C. Eissenberg, and H.J. Worman. 2001. Transcriptional repression of euchromatic genes by Drosophila heterochromatin protein 1 and histone modifiers. Proc. Natl. Acad. Sci. USA. 98:11423-11427.
9. Jacobs, S.A., S.D. Taverna, Y. Zhang, S.D. Briggs, J. Li, J.C. Eissenberg, C.D. Allis, and S. Khorasanizadeh. 2001. Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3. EMBO J. 20:5232-5241.
10. James, T.C., and S.C.R. Elgin. 1986. Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol. Cell. Biol. 6:3862-3872.
11. James, T.C., J.C. Eissenberg, C. Craig, V. Dietrich, A. Hobson, and S.C. Elgin. 1989. Distribution patterns of HP1, a heterochromatin-associated nonhistone chromosomal protein of Drosophila. Eur. J. Cell Biol. 50:170-180.
12. Kellum, R. 2003. HP1 complexes and heterochromatin assembly. In Curr. Top. Microbiol. Immunol, Vol. 274. J.L. Workman, ed. Springer-Verlag Berlin, Heidelberg, New York. 53-77.
13. Lachner, M., D. O'Carroll, S. Rea, K. Mechtler, and T. Jenuwein. 2001. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature. 410:116-120.
14. Maison, C., D. Bailly, A.H. Peters, J.P. Ouivy, D. Roche, A. Taddei, M. Lachner, T. Jenuwein, and G. Almouzni. 2002. Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component. Nat. Genet. 30:329-334.
15. Piacentini, L., L. Fanti, M. Berloco, B. Perrini, and S. Pimpinelli. 2003. Heterochromatin Protein 1 (HP1) is associated with induced gene expression in Drosophila euchromatin. J. Cell Biol. 161:707-714.
16. Reinhart, B.J., and D.P. Bartel. 2002. Small RNAs correspond to centromere heterochromatic repeats. Science. 297:1831.
17. Schotta, G., A. Ebert, V. Krauss, A. Fischer, J. Hoffmann, S. Rea, T. Jenuwein, R. Dorn, and G. Reuter. 2002. Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J. 21:1121-1131.
18. Volpe, T.A., C. Kidner, I.M. Hall, G. Teng, S.I. Grewal, and R.A. Martienssen. 2002. Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science. 297:1833-1837.
19. Wallrath, L.L., and S.C.R. Elgin. 1995. Position effect variegation in Drosophila is associated with an altered chromatin structure. Genes Dev. 9:1263-1277.