Animal models of antenatal corticosteroids: Clinical implications

Clinical Obstetrics and Gynecology

Volumn 46, Issue 1, 2003, Pages 174-189

  Jobe, Alan H ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETAMETHASONE; CORTICOSTEROID; DEXAMETHASONE; GLUCOCORTICOID;

CELL ULTRASTRUCTURE; DRUG EFFECT; FETUS GROWTH; FETUS LUNG MATURATION; FETUS WEIGHT; GESTATIONAL AGE; LUNG DEVELOPMENT; LUNG VOLUME; MESENCHYME CELL; NONHUMAN; PREMATURITY; PRENATAL DRUG EXPOSURE; RESPIRATORY DISTRESS SYNDROME; REVIEW;

ANIMALS; BETAMETHASONE; BRAIN; FEMALE; FETAL DISEASES; FETUS; GLUCOCORTICOIDS; GROWTH; HUMANS; LUNG; MODELS, ANIMAL; PREGNANCY; PRENATAL CARE; STRESS;

EID: 0037676345     PISSN: 00099201     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003081-200303000-00021     Document Type: Review

References (51)

1. Liggins GC, Howie RN. A controlled trial of antepartum glucocorticoid treatment for prevention of RDS in premature infants. Pediatrics. 1972;50:515-525.
2. Liggins GC: Premature delivery of fetal lambs infused with glucocorticoids. J Endocrinol. 1969;45:515-523.
3. Ballard PL. Hormones and lung maturation. Monographs on Endocrinology. New York: Springer-Verlag, 1986.
4. Mendelson CR, ed. Endocrinology of the lung: Development and surfactant synthesis. Totowa: Humana Press, 2000.
5. Jobe AH, Newnham J, Willet K, et al. Fetal versus maternal and gestational age effects of repetitive antenatal glucocorticoids. Pediatrics. 1998;101:1116-1125.
6. Jobe AH, Ikegami M. Fetal responses to glucocorticoids. In: Mendelson CR, ed. Endocrinology of the lung. Totawa: Humana Press, 2000:45-57.
7. Massaro DJ, Massaro GD. The regulation of the formation of pulmonary alveoli. In: Bland RD, Coalson JJ, eds. Chronic lung disease in early infancy. New York: Marcel Dekker, Inc., 2000:479-492.
8. Jobe AH. The new BPD: An arrest of lung development. Pediatr Res. 1999;46:641-643.
9. Tabor BL, Lewis JF, Ikegami M, et al. Corticosteroids and fetal intervention interact to alter lung maturation in preterm lambs. Pediatr Res. 1994;36:479-483.
10. Muglia LJ, Bae DS, Brown TT, et al. Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice. Am J Respir Cell Mol Biol. 1999;21:181-188.
11. Venihaki M, Carrigan A, Dikkes P, Majzoub JA. Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency. Proc Natl Acad Sci USA. 2000;97:7336-7341.
12. Cole TJ, Blendy JA, Monaghan AP, et al. Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Gene Develop. 1995;9:1608-1621.
13. Reichardt HM, Kaestner KH, Tuckermann J, et al. DNA binding of the glucocorticoid receptor is not essential for survival. Cell. 1998;23:531-541.
14. Tyson JE, Kennedy K, Broyles S, Rosenfeld CR. The small for gestational age infant: Accelerated or delayed pulmonary maturation? Increased or decreased survival? Pediatrics. 1995;16:534-538.
15. Watterberg KL, Scott SM, Naeye RL. Chorioamnionitis, cortisol, and acute lung disease in very low birth weight infants. Pediatrics. 1997;100:E6.
16. Jobe AH, Newnham JP, Willet KE, et al. Endotoxin induced lung maturation in preterm lambs is not mediated by cortisol. Am J Respir Crit Care Med. 2000;162:1656-1661.
17. Crowley P. Antenatal corticosteroid therapy: A meta-analysis of the randomized trials, 1972-1994. Am J Obstet Gynecol. 1995;173:322-335.
18. Tabor BL, Rider ED, Ikegami M, et al. Dose effects of antenatal corticosteroids for induction of lung maturation in preterm rabbits. Am J Obstet Gynecol. 1991;165:675-681.
19. Matthews SG. Antenatal glucocorticoids and programming of the developing CNS. Pediatr Res. 2000;47:291-300.
20. Johnson JWC, Mitzner W, Beck JC, et al. Long-term effects of betamethasone on fetal development. Am J Obstet Gynecol. 1981;141:1053-1061.
21. Johnson JWC, Mitzner W, London WT, et al. Glucocorticoids and the rhesus fetal lung. Am J Obstet Gynecol. 1978;132:905-916.
22. Bunton TE, Plopper CG. Triamcinolone-induced structural alterations in the development of the lung of the fetal rhesus macaque. Am J Obstet Gynecol. 1984;150:203-215.
23. Kessler DL, Truog WE, Murphy JH, et al. Experimental hyaline membrane disease in the premature monkey. Am Rev Respir Dis. 1982;126:62-69.
24. Seidner SR, Jobe AH, Coalson JJ, Ikegami M. Abnormal surfactant metabolism and function in preterm ventilated baboons. Am J Respir Crit Care Med. 1998;158:1982-1989.
25. Jobe AH, Polk D, Ikegami M, et al. Lung responses to ultrasound-guided fetal treatments with corticosteroids in preterm lambs. J Appl Physiol. 1993;75:2099-2105.
26. Ikegami M, Polk D, Jobe A. Minimum interval from fetal betamethasone treatment to postnatal lung responses in preterm lambs. Am J Obstet Gynecol. 1996;175:1408-1413.
27. Willet K, Jobe A, Ikegami M, et al. Antenatal endotoxin and glucocorticoid effects on lung morphometry in preterm lambs. Pediatr Res. 2000;48:782-788.
28. Ballard PL, Ning Y, Polk D, et al. Glucocorticoid regulation of surfactant components in immature lambs. Am J Physiol. 1997;273:L1048-L1057.
29. Tan RC, Ikegami M, Jobe AH, et al. Developmental and glucocorticoid regulation of surfactant protein mRNAs in preterm lambs. Am J Physiol. 1999;277:L1142-L1148.
30. Willet KE, Jobe AH, Ikegami M, et al. Pulmonary interstitial emphysema following intrauterine exposure to glucocorticoids in preterm sheep. Am J Respir Crit Care Med. 2000;162:1087-1094.
31. Ikegami M, Jobe AH, Newnham J, et al. Repetitive prenatal glucocorticoids improve lung function and decrease growth in preterm lambs. Am J Respir Crit Care Med. 1997;156:178-184.
32. Padbury JF, Polk DH, Ervin MG, et al. Postnatal cardiovascular and metabolic responses to a single intramuscular dose of betamethasone in fetal sheep born prematurely by cesarean section. Pediatr Res. 1995;38:709-715.
33. Berry LM, Polk DH, Ikegami M, et al. Preterm newborn lamb renal and cardiovascular responses after fetal or maternal antenatal betamethasone. Am J Physiol. 1997;27: R1972-R1979.
34. Jobe AH, Polk DH, Ervin MG, et al. Preterm betamethasone treatment of fetal sheep: Outcome after term delivery. J Soc Gynecol Invest. 1996;3:250-258.
35. Moss TJ, Sloboda DM, Gurrin LC, et al. Programming effects in sheep of prenatal growth restriction and glucocorticoid exposure. Am J Physiol Regul Integr Comp Physiol. 2001;281:R960-970.
36. Jobe AH, Wada N, Berry LM, et al. Single and repetitive maternal glucocorticoid exposures reduce fetal growth in sheep. Am J Obstet Gynecol. 1998;179:880-885.
37. Stewart JD, Sienko AE, Gonzalez CL, et al. Placebo-controlled comparison between a single dose and a multidose of betamethasone in accelerating lung maturation of mice offspring. Am J Obstet Gynecol. 1998;179:1241-1247.
38. Pratt L, Magness RR, Phernetton T, et al. Repeated use of betamethasone in rabbits: effects of treatment variation on adrenal suppression, pulmonary maturation, and pregnancy outcome. Am J Obstet Gynecol. 1999;181:995-1005.
39. Walther FJ, Jobe AH, Ikegami M. Repetitive prenatal glucocorticoid therapy reduces oxidative stress in the lungs of preterm lambs. J Appl Physiol. 1998;85:273-278.
40. Uno H, Lohmiller L, Thieme C, et al. Brain damage induced by prenatal exposure to dexamethasone in fetal rhesus macaques. Dev Brain Res. 1990;53:157-167.
41. Huang WL, Beazley LD, Quinlivan JA, et al. Effect of corticosteroids on brain growth in fetal sheep. Obstet Gynecol. 1999;93:213-218.
42. Quinlivan JA, Beazley LD, Evans SF, et al. Retinal maturation is delayed by repeated, but not single, maternal injections of beta-methasone in sheep. Eye. 2000;14:93-98.
43. Huang WL, Harper CG, Evans SF, et al. Repeated prenatal corticosteroid administration delays astrocyte and capillary tight junction maturation in fetal sheep. Int J Dev Neurosci. 2001;19:487-493.
44. Sloboda DM, Newnham JP, Challis JR. Effects of repeated maternal betamethasone administration on growth and hypothalamic-pituitary-adrenal function of the ovine fetus at term. J Endocrinol. 2000;167:79-91.
45. Falkenstein E, Tillmann HC, Christ M, et al. Multiple actions of steroid hormones: a focus on rapid, nongenomic effects. Pharmacol Rev. 2000;52:513-556.
46. Derks JB, Giussani DA, Van Dam LM, et al. Differential effects of betamethasone and dexamethasone fetal administration of parturition in sheep. J Soc Gynecol Investig. 1996;3:336-3341.
47. Baud O, Foix-L'Helias L, Kaminski M, et al. Antenatal glucocorticoid treatment and cystic periventricular leukomalacia in very premature infants. N Engl J Med. 1999;341:1190-1196.
48. Goldenberg RL, Hauth JC, Andrews WW. Intrauterine infection and preterm delivery. N Engl J Med. 2000;342:1500-1507.
49. Newnham JP, Moss TJ, Padbury JF, et al. The interactive effects of endotoxin with prenatal glucocorticoids on short-term lung function in sheep. Am J Obstet Gynecol. 2001;185:190-197.
50. Ehrenkranz RA, Younes N, Lemons JA, et al. Longitudinal growth of hospitalized very low birth weight infants. Pediatrics. 1999;20:280-289.
51. Jobe AH, Nesonham JP, Moss TJ, et al. Differential effects of maternal betamethasone and cortisol on lung maturation and growth in fetal sheep. Am J Obstet Gynecol. 2003;188:22-28.