-
1
-
-
0023279839
-
Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer
-
Sainsbury JRC, Farndon JR, Needham GK, Malcolm AJ, Harris AL: Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer. Lancet 1987;i:1398-1402.
-
(1987)
Lancet
, vol.1
, pp. 1398-1402
-
-
Sainsbury, J.R.C.1
Farndon, J.R.2
Needham, G.K.3
Malcolm, A.J.4
Harris, A.L.5
-
2
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SJ, Levin LJ, Ullrich A, McGuire WL: Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235:177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.J.3
Levin, L.J.4
Ullrich, A.5
McGuire, W.L.6
-
3
-
-
0025166350
-
Insulin-like growth factor receptor expression and function in human breast cancer
-
Cullen KJ, Yee D, Sly WS, Perdue J, Hampton B, Lippman ME, Rosen N: Insulin-like growth factor receptor expression and function in human breast cancer. Cancer Res 1990;50:48-53.
-
(1990)
Cancer Res
, vol.50
, pp. 48-53
-
-
Cullen, K.J.1
Yee, D.2
Sly, W.S.3
Perdue, J.4
Hampton, B.5
Lippman, M.E.6
Rosen, N.7
-
4
-
-
0029039421
-
Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors
-
Owens LV, Xu L, Craven RJ, Dent GA, Weiner TM, Kornberg L, Liu ET, Cance WG: Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors. Cancer Res 1995;55:2752-2755.
-
(1995)
Cancer Res
, vol.55
, pp. 2752-2755
-
-
Owens, L.V.1
Xu, L.2
Craven, R.J.3
Dent, G.A.4
Weiner, T.M.5
Kornberg, L.6
Liu, E.T.7
Cance, W.G.8
-
5
-
-
0025821436
-
FMS (CSF-1 receptor) and CSF-1 transcripts and protein are expressed by human breast carcinomas in vivo and in vitro
-
Kacinski BM, Scata KA, Carter D, Yee LD, Sapi E, King BL, Chambers SK, Jones MA, Pirro MH, Stanley ER, Rohrschneider LR: FMS (CSF-1 receptor) and CSF-1 transcripts and protein are expressed by human breast carcinomas in vivo and in vitro. Oncogene 1991;6:941-952.
-
(1991)
Oncogene
, vol.6
, pp. 941-952
-
-
Kacinski, B.M.1
Scata, K.A.2
Carter, D.3
Yee, L.D.4
Sapi, E.5
King, B.L.6
Chambers, S.K.7
Jones, M.A.8
Pirro, M.H.9
Stanley, E.R.10
Rohrschneider, L.R.11
-
7
-
-
0025204324
-
Putative tyrosine kinases expressed in K-562 human leukemia cells
-
Partanen J, Makela TP, Alitalo R, Lehvaslaiho H, Alitalo K: Putative tyrosine kinases expressed in K-562 human leukemia cells. Proc Natl Acad Sci USA 1990;87:8913-8917.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 8913-8917
-
-
Partanen, J.1
Makela, T.P.2
Alitalo, R.3
Lehvaslaiho, H.4
Alitalo, K.5
-
8
-
-
0026545092
-
A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains
-
Partanen J, Armstrong E, Makela TP, Korhonen J, Sandberg M, Renkonen R, Knuutila S, Huebner K, Alitalo K: A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains. Mol Cell Biol 1992;12:1698-1707.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 1698-1707
-
-
Partanen, J.1
Armstrong, E.2
Makela, T.P.3
Korhonen, J.4
Sandberg, M.5
Renkonen, R.6
Knuutila, S.7
Huebner, K.8
Alitalo, K.9
-
9
-
-
0028122465
-
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
-
Dumont DJ, Gradwohl G, Fong GH, Puri MC, Gertsenstein M, Auerbach A, Breitman ML: Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev 1994;8:1897-1909.
-
(1994)
Genes Dev
, vol.8
, pp. 1897-1909
-
-
Dumont, D.J.1
Gradwohl, G.2
Fong, G.H.3
Puri, M.C.4
Gertsenstein, M.5
Auerbach, A.6
Breitman, M.L.7
-
10
-
-
0029001244
-
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
-
Sato TN, Tozawa Y, Deutsch U, Wolburg-Buchholz K, Fujiwara Y, Gendron-Maquire M, Gridley T, Wolburg H, Risau W, Qin Y: Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995;376:70-74.
-
(1995)
Nature
, vol.376
, pp. 70-74
-
-
Sato, T.N.1
Tozawa, Y.2
Deutsch, U.3
Wolburg-Buchholz, K.4
Fujiwara, Y.5
Gendron-Maquire, M.6
Gridley, T.7
Wolburg, H.8
Risau, W.9
Qin, Y.10
-
11
-
-
0028867704
-
The receptor tyrosine kinase TIE is required for the integrity and survival of vascular endothelial cells
-
Puri MC, Rossant J, Alitalo K, Bernstein A, Partanen J: The receptor tyrosine kinase TIE is required for the integrity and survival of vascular endothelial cells. EMBO J 1995;14:5884-5891.
-
(1995)
EMBO J
, vol.14
, pp. 5884-5891
-
-
Puri, M.C.1
Rossant, J.2
Alitalo, K.3
Bernstein, A.4
Partanen, J.5
-
12
-
-
0026452135
-
Enhanced expression of the Tie-1 receptor tyrosine kinase in endothelial cells during neovascularization
-
Korhonen J, Partanen J, Armstrong E, Vaahtokari A, Elenius K, Jalkanen M, Alitalo K: Enhanced expression of the Tie-1 receptor tyrosine kinase in endothelial cells during neovascularization. Blood 1992;80:2548-2555.
-
(1992)
Blood
, vol.80
, pp. 2548-2555
-
-
Korhonen, J.1
Partanen, J.2
Armstrong, E.3
Vaahtokari, A.4
Elenius, K.5
Jalkanen, M.6
Alitalo, K.7
-
13
-
-
0030811667
-
Regulation of Tie-1 receptor expression on human endothelial cells by protein kinase C-mediated release of soluble Tie-1
-
Yabkowitz R, Meyer S, Yanagihara D, Brankow D, Staley T, Elliot G, Hu S, Ratzkin B: Regulation of Tie-1 receptor expression on human endothelial cells by protein kinase C-mediated release of soluble Tie-1. Blood 1997;90:706-715.
-
(1997)
Blood
, vol.90
, pp. 706-715
-
-
Yabkowitz, R.1
Meyer, S.2
Yanagihara, D.3
Brankow, D.4
Staley, T.5
Elliot, G.6
Hu, S.7
Ratzkin, B.8
-
14
-
-
0028938732
-
The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage
-
O'Bryan JP, Fridell YW, Koski R, Varnum B, Liu ET: The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage. J Biol Chem 1995;270:551-557.
-
(1995)
J Biol Chem
, vol.270
, pp. 551-557
-
-
O'Bryan, J.P.1
Fridell, Y.W.2
Koski, R.3
Varnum, B.4
Liu, E.T.5
-
15
-
-
0028151430
-
Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphotidylinositol 3′-kinase, and protein kinase C
-
Yee NS, Hsiau C-WM, Serve H, Vosseller K, Besmer P: Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphotidylinositol 3′-kinase, and protein kinase C. J Biol Chem 1994;269:31991-31998.
-
(1994)
J Biol Chem
, vol.269
, pp. 31991-31998
-
-
Yee, N.S.1
Hsiau, C.-W.M.2
Serve, H.3
Vosseller, K.4
Besmer, P.5
-
16
-
-
0024393702
-
Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms
-
Downing JR, Roussel MF, Sherr CJ: Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms. Mol Cell Biol 1989;9:2890-2896.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 2890-2896
-
-
Downing, J.R.1
Roussel, M.F.2
Sherr, C.J.3
-
17
-
-
0034671903
-
Evidence for heterotypic interaction between the receptor tyrosine kinases TIE-1 and TIE-2
-
Marron MB, Hughes DP, Edge MD, Forder CL, Brindle NPJ: Evidence for heterotypic interaction between the receptor tyrosine kinases TIE-1 and TIE-2. J Biol Chem 2000;275:39741-39746.
-
(2000)
J Biol Chem
, vol.275
, pp. 39741-39746
-
-
Marron, M.B.1
Hughes, D.P.2
Edge, M.D.3
Forder, C.L.4
Brindle, N.P.J.5
-
18
-
-
0034967966
-
Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells
-
Sartor CI, Zhou H, Kozlowska E, Guttridge K, Kawata E, Caskey L, Harrelson J, Hynes N, Ethier S, Calvo B, Earp HS 3rd: Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells. Mol Cell Biol 2001;21:4265-4275.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4265-4275
-
-
Sartor, C.I.1
Zhou, H.2
Kozlowska, E.3
Guttridge, K.4
Kawata, E.5
Caskey, L.6
Harrelson, J.7
Hynes, N.8
Ethier, S.9
Calvo, B.10
Earp H.S. III11
-
19
-
-
0025051384
-
Altered expression of the retinoblastoma gene product in human sarcomas
-
Cance WG, Brennan MF, Dudas ME, Huang CM, Cordon-Cardo C: Altered expression of the retinoblastoma gene product in human sarcomas. N Engl J Med 1990;323:1457-1462.
-
(1990)
N Engl J Med
, vol.323
, pp. 1457-1462
-
-
Cance, W.G.1
Brennan, M.F.2
Dudas, M.E.3
Huang, C.M.4
Cordon-Cardo, C.5
-
20
-
-
0034044795
-
Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: Correlation with preinvasive and invasive phenotypes
-
Cance WG, Harris JE, Iacocca MV, Roche E, Yang X, Chang J, Simkins S, Xu L: Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: Correlation with preinvasive and invasive phenotypes. Clin Cancer Res 2000;6:2417-2423.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2417-2423
-
-
Cance, W.G.1
Harris, J.E.2
Iacocca, M.V.3
Roche, E.4
Yang, X.5
Chang, J.6
Simkins, S.7
Xu, L.8
-
21
-
-
0032524104
-
Landscaping the cancer terrain
-
Kinzler KW, Vogelstein B: Landscaping the cancer terrain. Science 1998;280:1036-1037.
-
(1998)
Science
, vol.280
, pp. 1036-1037
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
22
-
-
0034787876
-
Cancer-associated myofibroblasts possess various factors to promote endometrial tumor progression
-
Orimo A, Tomioka Y, Shimizu Y, Sato M, Oigawa S, Kamata K, Nogi Y, Inoue S, Takahashi M, Hata T, Maramatsu M: Cancer-associated myofibroblasts possess various factors to promote endometrial tumor progression. Clin Cancer Res 2001;7:3097-3105.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3097-3105
-
-
Orimo, A.1
Tomioka, Y.2
Shimizu, Y.3
Sato, M.4
Oigawa, S.5
Kamata, K.6
Nogi, Y.7
Inoue, S.8
Takahashi, M.9
Hata, T.10
Maramatsu, M.11
-
23
-
-
0034778395
-
Soluble Tie2 and Flt1 extracellular domains in serum of patients with renal cancer and response to antiangiogenic therapy
-
Harris AL, Reusch P, Barleon B, Hang C, Dobbs N, Marme D: Soluble Tie2 and Flt1 extracellular domains in serum of patients with renal cancer and response to antiangiogenic therapy. Clin Cancer Res 2001;7:1992-1997.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1992-1997
-
-
Harris, A.L.1
Reusch, P.2
Barleon, B.3
Hang, C.4
Dobbs, N.5
Marme, D.6
-
24
-
-
0026071364
-
The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3
-
Zabrecky JR, Lam T, McKenzie SJ: The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3. J Biol Chem 1991;266:1716-1720.
-
(1991)
J Biol Chem
, vol.266
, pp. 1716-1720
-
-
Zabrecky, J.R.1
Lam, T.2
McKenzie, S.J.3
-
25
-
-
0027421333
-
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
-
Kendall RL, Thomas KA: Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci USA 1993;90:10705-10709.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10705-10709
-
-
Kendall, R.L.1
Thomas, K.A.2
-
27
-
-
0023663896
-
Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells
-
Di Fiore PP, Pierce JH, Fleming TP, Hazan R, Ullrich A, King CR, Schlessinger J, Aaronson SA: Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells. Cell 1987;51:1063-1070.
-
(1987)
Cell
, vol.51
, pp. 1063-1070
-
-
Di Fiore, P.P.1
Pierce, J.H.2
Fleming, T.P.3
Hazan, R.4
Ullrich, A.5
King, C.R.6
Schlessinger, J.7
Aaronson, S.A.8
-
28
-
-
0026010027
-
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase
-
O'Bryan JP, Frye RA, Cogswell PC, Neubauer A, Kitch B, Prokop C, Espinosa R 3rd, Le Beau MM, Earp HS, Liu ET: axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. Mol Cell Biol 1991;11:5016-5031.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 5016-5031
-
-
O'Bryan, J.P.1
Frye, R.A.2
Cogswell, P.C.3
Neubauer, A.4
Kitch, B.5
Prokop, C.6
Espinosa R. III7
Le Beau, M.M.8
Earp, H.S.9
Liu, E.T.10
-
29
-
-
0034730632
-
The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells
-
Xu L-H, Yang X, Bradham CA, Brenner DA, Baldwin AS, Craven RJ, Cance WG: The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. J Biol Chem 2000;275:30597-30604.
-
(2000)
J Biol Chem
, vol.275
, pp. 30597-30604
-
-
Xu, L.-H.1
Yang, X.2
Bradham, C.A.3
Brenner, D.A.4
Baldwin, A.S.5
Craven, R.J.6
Cance, W.G.7
-
30
-
-
0035799531
-
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
-
Garcia R, Bowman TL, Niu G, Yu H, Minton S, Muro-Cacho CA, Cox CE, Falcone R, Fairclough R, Parsons S, Laudano A, Gazit A, Levitzki A, Kraker A, Jove R: Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 2001;20:2499-2513.
-
(2001)
Oncogene
, vol.20
, pp. 2499-2513
-
-
Garcia, R.1
Bowman, T.L.2
Niu, G.3
Yu, H.4
Minton, S.5
Muro-Cacho, C.A.6
Cox, C.E.7
Falcone, R.8
Fairclough, R.9
Parsons, S.10
Laudano, A.11
Gazit, A.12
Levitzki, A.13
Kraker, A.14
Jove, R.15
-
31
-
-
0034677776
-
HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway
-
Zhou BP, Hu MC, Miller SA, Yu Z, Xia W, Lin SY, Hung MC: HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway. J Biol Chem 2000;275:8027-8031.
-
(2000)
J Biol Chem
, vol.275
, pp. 8027-8031
-
-
Zhou, B.P.1
Hu, M.C.2
Miller, S.A.3
Yu, Z.4
Xia, W.5
Lin, S.Y.6
Hung, M.C.7
-
32
-
-
0035422178
-
Vascular endothelial growth factor is an autocrine survival signal for neuropilin-expressing breast carcinoma cells
-
Bachelder RE, Crago A, Chung J, Wendt MA, Shaw LA, Robinson G, Mercurio AM: Vascular endothelial growth factor is an autocrine survival signal for neuropilin-expressing breast carcinoma cells. Cancer Res 2001;15:5736-5740.
-
(2001)
Cancer Res
, vol.15
, pp. 5736-5740
-
-
Bachelder, R.E.1
Crago, A.2
Chung, J.3
Wendt, M.A.4
Shaw, L.A.5
Robinson, G.6
Mercurio, A.M.7
-
33
-
-
0036181270
-
The endothelial receptor tyrosine kinase Tie1 activates phosphotidylinositol 3-kinase and Akt to inhibit apoptosis
-
Kontos CD, Cha EH, York JD, Peters KG: The endothelial receptor tyrosine kinase Tie1 activates phosphotidylinositol 3-kinase and Akt to inhibit apoptosis. Mol Cell Biol 2002;22:1704-1713.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1704-1713
-
-
Kontos, C.D.1
Cha, E.H.2
York, J.D.3
Peters, K.G.4
-
34
-
-
0021281324
-
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
-
Downward J, Yarden Y, Mayes E, Scrace G, Totty N, Stockwell P, Ullrich A, Schlessinger J, Waterfield MD: Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature 1984;307:521-527.
-
(1984)
Nature
, vol.307
, pp. 521-527
-
-
Downward, J.1
Yarden, Y.2
Mayes, E.3
Scrace, G.4
Totty, N.5
Stockwell, P.6
Ullrich, A.7
Schlessinger, J.8
Waterfield, M.D.9
-
35
-
-
0030015787
-
Endothelial Tie-1 growth factor receptor provides antigenic marker for assessment of breast cancer angiogenesis
-
Salven P, Joensuu H, Heikkila P, Matikainen M-T, Wasenius V-M, Alanko A, Alitalo K: Endothelial Tie-1 growth factor receptor provides antigenic marker for assessment of breast cancer angiogenesis. Br J Cancer 1996;74:69-72.
-
(1996)
Br J Cancer
, vol.74
, pp. 69-72
-
-
Salven, P.1
Joensuu, H.2
Heikkila, P.3
Matikainen, M.-T.4
Wasenius, V.-M.5
Alanko, A.6
Alitalo, K.7
-
36
-
-
0034902317
-
Tie-1 tyrosine kinase is an independent prognostic indicator for invasive breast cancer
-
Tseng L-M, Hsu C-Y, Wang H-C, Liu JM, Chang H-M, Lo S-S, Wu C-W, Lui W-Y, Chi C-W: Tie-1 tyrosine kinase is an independent prognostic indicator for invasive breast cancer. Anticancer Res 2001;21:2163-2170.
-
(2001)
Anticancer Res
, vol.21
, pp. 2163-2170
-
-
Tseng, L.-M.1
Hsu, C.-Y.2
Wang, H.-C.3
Liu, J.M.4
Chang, H.-M.5
Lo, S.-S.6
Wu, C.-W.7
Lui, W.-Y.8
Chi, C.-W.9
-
37
-
-
0032767069
-
Tie-1 protein tyrosine kinase: A novel independent prognostic marker for gastric cancer
-
Lin W-C, Li AF-Y, Chi C-W, Chung W-W, Huang CL, Lui W-Y, Kung H-J, Wu C-W: Tie-1 protein tyrosine kinase: A novel independent prognostic marker for gastric cancer. Clin Cancer Res 1999;5:1745-1751.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1745-1751
-
-
Lin, W.-C.1
Li, A.F.-Y.2
Chi, C.-W.3
Chung, W.-W.4
Huang, C.L.5
Lui, W.-Y.6
Kung, H.-J.7
Wu, C.-W.8
-
38
-
-
0033168916
-
Two independent mechanisms essential for tumor angiogenesis: Inhibition of human melanoma xenograph growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway
-
Siemeister G, Schirner M, Weindel K, Reusch P, Menrad A, Marme D, Martiny-Baron G: Two independent mechanisms essential for tumor angiogenesis: Inhibition of human melanoma xenograph growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway. Cancer Res 1999;59:3185-3191.
-
(1999)
Cancer Res
, vol.59
, pp. 3185-3191
-
-
Siemeister, G.1
Schirner, M.2
Weindel, K.3
Reusch, P.4
Menrad, A.5
Marme, D.6
Martiny-Baron, G.7
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