Differential activation and redistribution of c-Src and Fyn in platelets, assessed by MoAb specific for C-terminal tyrosine-dephosphorylated c-Src and Fyn

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1497, Issue 1, 2000, Pages 27-36

  Wu, Yi ^a   Ozaki, Yukio ^a   Inoue, Katsue ^a   Satoh, Kaneo ^a   Ohmori, Tsukasa ^a   Yatomi, Yutaka ^a   Owada, Koji ^b  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

c Src; Fyn; Platelet; Thrombin; Tyr 530 dephosphorylation; Tyrosine kinase

Indexed keywords

PROTEIN TYROSINE KINASE; THROMBIN; THROMBIN RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DEPHOSPHORYLATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; ONCOGENE FYN; ONCOGENE SRC; PRIORITY JOURNAL; RADIOIMMUNOPRECIPITATION; THROMBOCYTE METABOLISM;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; BLOOD PLATELETS; CELL FRACTIONATION; HUMANS; MOLECULAR SEQUENCE DATA; OCTOXYNOL; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FYN; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RADIOIMMUNOPRECIPITATION ASSAY; SOLUBILITY; SUBCELLULAR FRACTIONS; TYROSINE;

EID: 0034595575     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4889(00)00043-4     Document Type: Article

References (37)

1. Wong S., Reynolds A.B., Papkoff J. Platelet activation leads to increased c-Src kinase activity and association of c-Src with an 85-kDa tyrosine phosphoprotein. Oncogene. 7:1992;2407-2415.
2. Liebenhoff U., Greinacher A., Presek P. The protein tyrosine kinase pp60c-src is activated upon platelet stimulation. Cell. Mol. Biol. 40:1994;645-652.
3. Liebenhoff U., Brockmeier D., Presek P. Substrate affinity of the protein tyrosine kinase pp60c-src is increased on thrombin stimulation of human platelets. Biochem. J. 295:1993;41-48.
4. Clark E.A., Brugge J.S. Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets. Mol. Cell. Biol. 13:1993;1863-1871.
5. Ichinohe T., Takayama H., Ezumi Y., Yanagi S., Yamamura H., Okuma M. Cyclic AMP-insensitive activation of c-Src and Syk protein-tyrosine kinases through platelet membrane glycoprotein VI. J. Biol. Chem. 270:1995;28029-28036.
6. Cooper J.A., Gould K.L., Cartwright C.A., Hunter T. Tyr 527 is phosphorylated in pp60c-src implications for regulation. Science. 231:1986;1431-1434.
7. Cooper J.A., King C.S. Dephosphorylation of antibody binding to the carboxy terminus stimulates pp60c-src. Mol. Cell. Biol. 6:1986;4467-4477.
8. Okada M., Nakagawa H. A protein tyrosine kinase involved in regulation of pp60c-src function. J. Biol. Chem. 264:1989;20886-20893.
9. Okada M., Nada S., Yamanashi Y., Yamamoto T., Nakagawa H. Csk: a protein-tyrosine kinase involved in regulation of Src family kinases. J. Biol. Chem. 266:1991;24249-24252.
10. Nada S., Okada M., MacAuley A., Cooper J.A., Nakagawa H. Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulation site of pp60c-src. Nature. 351:1991;69-72.
11. Falet H., Ramos-Morales F., Bachelot C., Fischer S., Rendu F. Association of the protein tyrosine phosphatase PTP1C with the protein tyrosine kinase c-Src in human platelets. FEBS Lett. 383:1996;165-169.
12. Somani A.K., Bignon J.S., Mills G.B., Siminovitch K.A., Branch D.R. Src kinase activity is regulated by the SHP-1 protein-tyrosine phosphatase. J. Biol. Chem. 272:1997;21113-21119.
13. Kawakatsu H., Sakai T., Takagaki Y., Shinoda Y., Saito M., Owada M.K., Yano J. A new monoclonal antibody which selectively recognizes the active form of Src tyrosine kinase. J. Biol. Chem. 271:1996;5680-5685.
14. Kawakami T., Pennington C.Y., Robbins K.C. Isolation and oncogenic potential of a novel human src-like gene. Mol. Cell. Biol. 6:1986;4195-4201.
15. Satoh K., Ozaki Y., Asazuma N., Yatomi Y., Qi R., Kuroda K., Yang L., Kume S. Differential mobilization of tyrosine kinases in human platelets stimulated with thrombin or thrombin receptor agonist peptide. Biochem. Biophys. Res. Commun. 225:1996;1084-1089.
16. Asazuma N., Ozaki Y., Satoh K., Yatomi Y., Handa M., Fujimura Y., Miura S., Kume S. Glycoprotein Ib-von Willebrand factor interactions activate tyrosine kinases in human platelets. Blood. 12:1997;4789-4798.
17. Horvath A.R., Muszbek L., Kellie S. Translocation of pp60c-src to the cytoskeleton during platelet aggregation. EMBO J. 11:1992;855-861.
18. Oda A., Drucker B.J., Smith M., Salzman E.W. Association of pp60src with Triton X-100-insoluble residue in human blood platelets requires platelet aggregation and actin polymerization. J. Biol. Chem. 267:1992;20075-20081.
19. Berditchevski F., Zutter M.M., Hemler M.E. Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins). Mol. Biol. Cell. 7:1996;193-207.
20. Su J., Muranjan M., Sap J. Receptor protein tyrosine phosphotase α activates Src-family kinases and controls integrin-mediated responses in fibroblasts. Curr. Biol. 9:1999;505-511.
21. Grondin P., Plantavid M., Sultan C., Breton M., Gauco G., Chap H. Interaction of pp60c-src, phospholipase C, inositol-lipid, and diacyglycerol kinases with the cytoskeletons of thrombin-stimulated platelets. J. Biol. Chem. 266:1991;15705-15709.
22. Hirao A., Hamaguchi I., Suda T., Yamaguchi N. Translocation of the Csk homologous kinase (Chk/Hyl) controls activity of CD 36-anchored Lyn tyrosine kinase in thrombin-stimulated platelets. EMBO J. 16:1997;2342-2351.
23. Golden A., Brugge J.S. Thrombin treatment induces rapid changes in tyrosine phosphorylation in platelets. Proc. Natl. Acad. Sci. USA. 86:1989;901-905.
24. Horak I.D., Corcoran M.L., Thompson P.A., Wahl L.M., Bolen J.B. Expression of p60fyn in human platelets. Oncogene. 5:1990;597-602.
25. Gutkind J.S., Lacal P.M., Robbins K.C. Thrombin-dependent association of phosphatidylinositol-3 kinase with p60c-src and p59fyn in human platelets. Mol. Cell. Biol. 10:1990;3806-3809.
26. Chen Y., Pouyssegur J.P., Courtneidge S.A., VanObberghen-Schilling E. Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts. J. Biol. Chem. 269:1994;27372-27377.
27. Fukui Y., O'Brien M.C., Hanafusa H. Deletions in the SH2 domain of p60v-src prevent association with the detergent-insoluble cellular matrix. Mol. Cell. Biol. 11:1991;1207-1213.
28. Kuppuswamy D., Kerr C., Narishige T., Kasi V.S., Menick D.R., Cooper I.V.G. Association of tyrosine-phosphorylated c-src with the cytoskeleton of hypertrophying myocardium. J. Biol. Chem. 272:1997;4500-4508.
29. Hamaguchi M., Hanafusa H. Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation. Proc. Natl. Acad. Sci. USA. 84:1987;2312-2316.
30. Schwartzberg P.L. The many faces of Src multiple functions of prototypical tyrosine kinase. Oncogene. 17:1998;1463-1468.
31. Janmey P.A. The cytoskeleton and cell signaling: component localization and mechanical coupling. Physiol. Res. 78:1998;763-781.
32. Okamura H., Resh M.D. Differential binding of pp60c-src and pp60v-src to cytoskeleton is mediated by SH2 and catalytic domains. Oncogene. 9:1994;2293-2303.
33. Kaplan K.B., Bibbins K.B., Swedlow J.R., Arnaud M., Morgan D.O., Varmus H.E. Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. EMBO J. 13:1994;4745-4756.
34. Dorahy D.J., Berndt M.C., Burns G.F. Capture by chemical crosslinkers provides evidence that integrin αIIbβ3 forms a complex with protein tyrosine kinases in intact platelets. Biochem. J. 309:1995;481-490.
35. Kralisz U., Cierniewski C.S. Association of pp60c-src with integrin αIIbβ3 in resting platelets. Biochem. Mol. Biol. Int. 45:1998;735-743.
36. Chow L.M., Davidson D., Fournel M., Gosselin P., Lemieux S., Lyu M.S., Kozak C.A., Matis L.A., Veillette A. Two distinct protein isoforms are encoded by ntk, a csk-related tyrosine protein kinase gene. Oncogene. 9:1994;3437-3448.
37. Schaller M.D., Otey C.A., Hildebrand J.D., Parsons J.T. Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains. J. Cell. Biol. 130:1995;1181-1187.