ANTINEOPLASTIC ACTIVITY;
CANCER MODEL;
DRUG CYTOTOXICITY;
DRUG EFFECT;
DRUG EFFICACY;
DRUG POTENTIATION;
DRUG TOXICITY;
HUMAN;
KIDNEY CANCER;
MELANOMA;
NONHUMAN;
OXIDATIVE STRESS;
PRIORITY JOURNAL;
SHORT SURVEY;
SOLID TUMOR;
Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
Fyfe, G. et al. Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J. Clin. Oncol. 13, 688-696 (1995).
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993
Atkins, M.B. et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J. Clin. Oncol. 17, 2105-2116 (1999).
A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects
Samlowski, W.E. et al. A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects. Nat. Med. 9. 750-755 (2003).
Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock
Macarthur, H., Westfall, T.C., Riley, D.P., Misko, T.P. & Salvemini, D. Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock. Proc. Natl. Acad. Sci. USA 97, 9753-9758 (2000).
Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy
Hibbs, J.B. Jr. et al. Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy. J. Clin. Invest. 89, 867-877 (1992).
Randomized placebo-controlled clinical trial of high dose interleukin-2 in combination with soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma
Dubois, J. et al. Randomized placebo-controlled clinical trial of high dose interleukin-2 in combination with soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma. J. Clin. Oncol. 15, 1052-1061 (1997).
A two-part phase I trial of high dose interleukin-2 in combination with soluble Chinese hamster ovary IL-1 receptor
McDermott, D. et al. A two-part phase I trial of high dose interleukin-2 in combination with soluble Chinese hamster ovary IL-1 receptor. Clin. Cancer Res. 5, 1203-1213 (1998).
Prospective randomized trial of lisofylline for the prevention of toxicities of high-dose interleukin 2 therapy in advanced renal cancer and malignant melanoma
Margolin, K. et al. Prospective randomized trial of lisofylline for the prevention of toxicities of high-dose interleukin 2 therapy in advanced renal cancer and malignant melanoma. Clin. Cancer Res. 3, 565-572 (1997).