-
1
-
-
0030448021
-
Functions of ceramide in coordinating cellular responses to stress
-
Hannun Y.A. Functions of ceramide in coordinating cellular responses to stress. Science. 274:1996;1855-1859.
-
(1996)
Science
, vol.274
, pp. 1855-1859
-
-
Hannun, Y.A.1
-
2
-
-
0028108015
-
Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling
-
Wiegmann K., Schutze S., Machleidt T., Witte D., Kronke M. Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell. 78:1994;1005-1015.
-
(1994)
Cell
, vol.78
, pp. 1005-1015
-
-
Wiegmann, K.1
Schutze, S.2
Machleidt, T.3
Witte, D.4
Kronke, M.5
-
3
-
-
0029127286
-
Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity
-
Tepper C.G., Jayadev S., Liu B., Bielawska A., Wolff R., Yonehara S., Hannun Y.A., Seldin M.F. Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity. Proc. Natl. Acad. Sci. USA. 92:1995;8443-8447.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8443-8447
-
-
Tepper, C.G.1
Jayadev, S.2
Liu, B.3
Bielawska, A.4
Wolff, R.5
Yonehara, S.6
Hannun, Y.A.7
Seldin, M.F.8
-
4
-
-
0028176730
-
1-β-D-Arabinofuranosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells
-
Strum J.C., Small G.W., Pauig S.B., Daniel L.W. 1-β-D-Arabinofuranosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells. J. Biol. Chem. 269:1994;15493-15497.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15493-15497
-
-
Strum, J.C.1
Small, G.W.2
Pauig, S.B.3
Daniel, L.W.4
-
5
-
-
0030006040
-
Daunorubicin-induced apoptosis: Triggering of ceramide generation through sphingomyelin hydrolysis
-
Jaffrezou J.P., Levade T., Bettaieb A., Andrieu N., Bezombes C., Maestre N., Vermeersch S., Rousse A., Laurent G. Daunorubicin-induced apoptosis triggering of ceramide generation through sphingomyelin hydrolysis . EMBO J. 15:1996;2417-2424.
-
(1996)
EMBO J.
, vol.15
, pp. 2417-2424
-
-
Jaffrezou, J.P.1
Levade, T.2
Bettaieb, A.3
Andrieu, N.4
Bezombes, C.5
Maestre, N.6
Vermeersch, S.7
Rousse, A.8
Laurent, G.9
-
6
-
-
0034708594
-
Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis
-
Perry D.K., Carton J., Shah A.K., Meredith F., Uhlinger D.J., Hannun Y.A. Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis. J. Biol. Chem. 275:2000;9078-9084.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9078-9084
-
-
Perry, D.K.1
Carton, J.2
Shah, A.K.3
Meredith, F.4
Uhlinger, D.J.5
Hannun, Y.A.6
-
7
-
-
0028287960
-
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis
-
Haimovitz-Friedman A., Kan C.C., Ehleiter D., Persaud R.S., McLoughlin M., Fuks Z., Kolesnick R.N. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J. Exp. Med. 180:1994;525-535.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 525-535
-
-
Haimovitz-Friedman, A.1
Kan, C.C.2
Ehleiter, D.3
Persaud, R.S.4
McLoughlin, M.5
Fuks, Z.6
Kolesnick, R.N.7
-
8
-
-
0347537940
-
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
-
Verheij M., Bose R., Lin X.H., Yao B., Jarvis W.D., Grant S., Birrer M.J., Szabo E., Zon L.I., Kyriakis J.M., Haimovitz-Friedman A., Fuks Z., Kolesnick R.N. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature. 380:1996;75-79.
-
(1996)
Nature
, vol.380
, pp. 75-79
-
-
Verheij, M.1
Bose, R.2
Lin, X.H.3
Yao, B.4
Jarvis, W.D.5
Grant, S.6
Birrer, M.J.7
Szabo, E.8
Zon, L.I.9
Kyriakis, J.M.10
Haimovitz-Friedman, A.11
Fuks, Z.12
Kolesnick, R.N.13
-
9
-
-
0024795059
-
Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation
-
Okazaki T., Bell R.M., Hannun Y.A. Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation. J. Biol. Chem. 264:1989;19076-19080.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 19076-19080
-
-
Okazaki, T.1
Bell, R.M.2
Hannun, Y.A.3
-
10
-
-
0026534541
-
Elevated ceramide levels in GH4C1 cells treated with retinoic acid
-
Kalen A., Borchardt R.A., Bell R.M. Elevated ceramide levels in GH4C1 cells treated with retinoic acid. Biochim. Biophys. Acta. 1125:1992;90-96.
-
(1992)
Biochim. Biophys. Acta
, vol.1125
, pp. 90-96
-
-
Kalen, A.1
Borchardt, R.A.2
Bell, R.M.3
-
11
-
-
0025992755
-
Sphingomyelin synthesis is involved in adherence during macrophage differentiation of HL-60 cells
-
Dressler K.A., Kan C.C., Kolesnick R.N. Sphingomyelin synthesis is involved in adherence during macrophage differentiation of HL-60 cells. J. Biol. Chem. 266:1991;11522-11527.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 11522-11527
-
-
Dressler, K.A.1
Kan, C.C.2
Kolesnick, R.N.3
-
12
-
-
0025003424
-
Role of ceramide as a lipid mediator of 1 α,25-dihydroxyvitamin D3-induced HL-60 cell differentiation
-
Okazaki T., Bielawska A., Bell R.M., Hannun Y.A. Role of ceramide as a lipid mediator of 1 α,25-dihydroxyvitamin D3-induced HL-60 cell differentiation. J. Biol. Chem. 265:1990;15823-15831.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 15823-15831
-
-
Okazaki, T.1
Bielawska, A.2
Bell, R.M.3
Hannun, Y.A.4
-
14
-
-
0343742670
-
Kinase suppressor of Ras is ceramide-activated protein kinase
-
Zhang Y., Yao B., Delikat S., Bayoumy S., Lin X.H., Basu S., McGinley M., Chan-Hui P.Y., Lichenstein H., Kolesnick R. Kinase suppressor of Ras is ceramide-activated protein kinase. Cell. 89:1997;63-72.
-
(1997)
Cell
, vol.89
, pp. 63-72
-
-
Zhang, Y.1
Yao, B.2
Delikat, S.3
Bayoumy, S.4
Lin, X.H.5
Basu, S.6
McGinley, M.7
Chan-Hui, P.Y.8
Lichenstein, H.9
Kolesnick, R.10
-
16
-
-
0028846952
-
Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells
-
Sawai H., Okazaki T., Yamamoto H., Okano H., Takeda Y., Tashima M., Sawada H., Okuma M., Ishikura H., Umehara H., Domae N. Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells. J. Biol. Chem. 270:1995;27326-27331.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27326-27331
-
-
Sawai, H.1
Okazaki, T.2
Yamamoto, H.3
Okano, H.4
Takeda, Y.5
Tashima, M.6
Sawada, H.7
Okuma, M.8
Ishikura, H.9
Umehara, H.10
Domae, N.11
-
17
-
-
0029003788
-
PKC ζ is a molecular switch in signal transduction of TNF-α, bifunctionally regulated by ceramide and arachidonic acid
-
Muller G., Ayoub M., Storz P., Rennecke J., Fabbro D., Pfizenmaier K. PKC ζ is a molecular switch in signal transduction of TNF-α, bifunctionally regulated by ceramide and arachidonic acid. EMBO J. 14:1995;1961-1969.
-
(1995)
EMBO J.
, vol.14
, pp. 1961-1969
-
-
Muller, G.1
Ayoub, M.2
Storz, P.3
Rennecke, J.4
Fabbro, D.5
Pfizenmaier, K.6
-
18
-
-
0034607914
-
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473
-
Schubert K.M., Scheid M.P., Duronio V. Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. J. Biol. Chem. 275:2000;13330-13335.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13330-13335
-
-
Schubert, K.M.1
Scheid, M.P.2
Duronio, V.3
-
19
-
-
15844387528
-
Ceramide inactivates cellular protein kinase Cα
-
Lee J.Y., Hannun Y.A., Obeid L.M. Ceramide inactivates cellular protein kinase Cα J. Biol. Chem. 271:1996;13169-13174.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13169-13174
-
-
Lee, J.Y.1
Hannun, Y.A.2
Obeid, L.M.3
-
20
-
-
0035827632
-
CD95 signaling via ceramide-rich membrane rafts
-
Grassme H., Jekle A., Riehle A., Schwarz H., Berger J., Sandhoff K., Kolesnick R., Gulbins E. CD95 signaling via ceramide-rich membrane rafts. J. Biol. Chem. 276:2001;20589-20596.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20589-20596
-
-
Grassme, H.1
Jekle, A.2
Riehle, A.3
Schwarz, H.4
Berger, J.5
Sandhoff, K.6
Kolesnick, R.7
Gulbins, E.8
-
21
-
-
12444311096
-
Isolation of a variant cell line resistant to C2-ceramide from human leukemia HL-60 cells
-
Kawai S. Isolation of a variant cell line resistant to C2-ceramide from human leukemia HL-60 cells. FASEB J. 11:1997;A1173.
-
(1997)
FASEB J.
, vol.11
, pp. 1173
-
-
Kawai, S.1
-
22
-
-
0031035381
-
Ceramide-induced translocation of protein kinase C-δ and -ε to the cytosol. Implications in apoptosis
-
Sawai H., Okazaki T., Takeda Y., Tashima M., Sawada H., Okuma M., Kishi S., Umehara H., Domae N. Ceramide-induced translocation of protein kinase C-δ and -ε to the cytosol. Implications in apoptosis. J. Biol. Chem. 272:1997;2452-2458.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2452-2458
-
-
Sawai, H.1
Okazaki, T.2
Takeda, Y.3
Tashima, M.4
Sawada, H.5
Okuma, M.6
Kishi, S.7
Umehara, H.8
Domae, N.9
-
23
-
-
0026975039
-
HL-60 cells isolated for resistance to vincristine are defective in 12-O-tetradecanoylphorbol-13-acetate induced differentiation and the formation of a functional AP-1 complex
-
Ma L., Krishnamachary N., Perbal B., Center M.S. HL-60 cells isolated for resistance to vincristine are defective in 12-O-tetradecanoylphorbol-13-acetate induced differentiation and the formation of a functional AP-1 complex. Oncol. Res. 4:1992;291-298.
-
(1992)
Oncol. Res.
, vol.4
, pp. 291-298
-
-
Ma, L.1
Krishnamachary, N.2
Perbal, B.3
Center, M.S.4
-
24
-
-
13344259987
-
Proteolytic activation of protein kinase C δ by an ICE-like protease in apoptotic cells
-
Emoto Y., Manome Y., Meinhardt G., Kisaki H., Kharbanda S., Robertson M., Ghayur T., Wong W.W., Kamen R., Weichselbaum R., Kufe D. Proteolytic activation of protein kinase C δ by an ICE-like protease in apoptotic cells. EMBO J. 14:1995;6148-6156.
-
(1995)
EMBO J.
, vol.14
, pp. 6148-6156
-
-
Emoto, Y.1
Manome, Y.2
Meinhardt, G.3
Kisaki, H.4
Kharbanda, S.5
Robertson, M.6
Ghayur, T.7
Wong, W.W.8
Kamen, R.9
Weichselbaum, R.10
Kufe, D.11
-
25
-
-
0030023982
-
Activation of protein kinase Cδ in human myeloid leukemia cells treated with 1-β-D-arabinofuranosylcytosine
-
Emoto Y., Kisaki H., Manome Y., Kharbanda S., Kufe D. Activation of protein kinase Cδ in human myeloid leukemia cells treated with 1-β-D-arabinofuranosylcytosine. Blood. 87:1996;1990-1996.
-
(1996)
Blood
, vol.87
, pp. 1990-1996
-
-
Emoto, Y.1
Kisaki, H.2
Manome, Y.3
Kharbanda, S.4
Kufe, D.5
-
26
-
-
12644268232
-
Proteolytic activation of protein kinase C δ by an ICE/CED 3-like protease induces characteristics of apoptosis
-
Ghayur T., Hugunin M., Talanian R.V., Ratnofsky S., Quinlan C., Emoto Y., Pandey P., Datta R., Huang Y., Kharbanda S., Allen H., Kamen R., Wong W., Kufe D. Proteolytic activation of protein kinase C δ by an ICE/CED 3-like protease induces characteristics of apoptosis. J. Exp. Med. 184:1996;2399-2404.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 2399-2404
-
-
Ghayur, T.1
Hugunin, M.2
Talanian, R.V.3
Ratnofsky, S.4
Quinlan, C.5
Emoto, Y.6
Pandey, P.7
Datta, R.8
Huang, Y.9
Kharbanda, S.10
Allen, H.11
Kamen, R.12
Wong, W.13
Kufe, D.14
-
27
-
-
85047683702
-
Protein kinase Cδ amplifies ceramide formation via mitochondrial signaling in prostate cancer cells
-
Sumitomo M., Ohba M., Asakuma J., Asano T., Kuroki T., Hayakawa M. Protein kinase Cδ amplifies ceramide formation via mitochondrial signaling in prostate cancer cells. J. Clin. Invest. 109:2002;827-836.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 827-836
-
-
Sumitomo, M.1
Ohba, M.2
Asakuma, J.3
Asano, T.4
Kuroki, T.5
Hayakawa, M.6
-
28
-
-
0030734628
-
The proteolytic cleavage of protein kinase C isotypes, which generates kinase and regulatory fragments, correlates with Fas-mediated and 12-O-tetradecanoyl-phorbol-13-acetate-induced apoptosis
-
Mizuno K., Noda K., Araki T., Imaoka T., Kobayashi Y., Akita Y., Shimonaka M., Kishi S., Ohno S. The proteolytic cleavage of protein kinase C isotypes, which generates kinase and regulatory fragments, correlates with Fas-mediated and 12-O-tetradecanoyl-phorbol-13-acetate-induced apoptosis. Eur. J. Biochem. 250:1997;7-18.
-
(1997)
Eur. J. Biochem.
, vol.250
, pp. 7-18
-
-
Mizuno, K.1
Noda, K.2
Araki, T.3
Imaoka, T.4
Kobayashi, Y.5
Akita, Y.6
Shimonaka, M.7
Kishi, S.8
Ohno, S.9
-
29
-
-
0039765390
-
Involvement of protein kinase C δ (PKCδ) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCδ
-
Fujii T., Garcia-Bermejo M.L., Bernabo J.L., Caamano J., Ohba M., Kuroki T., Li L., Yuspa S.H., Kazanietz M.G. Involvement of protein kinase C δ (PKCδ) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCδ J. Biol. Chem. 275:2000;7574-7582.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7574-7582
-
-
Fujii, T.1
Garcia-Bermejo, M.L.2
Bernabo, J.L.3
Caamano, J.4
Ohba, M.5
Kuroki, T.6
Li, L.7
Yuspa, S.H.8
Kazanietz, M.G.9
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