GAP43 stimulates inositol trisphosphate-mediated calcium release in response to hypotonicity

EMBO Journal

Volumn 22, Issue 12, 2003, Pages 3004-3014

  Caprini, Marco ^a   Gomis, Ana ^a   Cabedo, Hugo ^a,b   Planells Cases, Rosa ^a   Belmonte, Carlos ^a   Viana, Félix ^a   Ferrer Montiel, Antonio ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b HOSPITAL UNIVERSITARIO DE SAN JUAN   (Spain)

Author keywords

Actin cytoskeleton; Dorsal root ganglion; Mechanotransduction; Phosphoinositides; PLC

Indexed keywords

ACTIN; CALCIUM; COMPLEMENTARY DNA; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL TRISPHOSPHATE; NEUROMODULIN; PHOSPHOLIPASE C;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; DNA LIBRARY; ENZYME ACTIVITY; GROWTH CONE; HUMAN; HUMAN CELL; MECHANORECEPTOR; MOLECULAR CLONING; MUSCLE HYPOTONIA; NERVE CELL PLASTICITY; NERVE FIBER; OSMORECEPTION; PALMITOYLATION; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; SPINAL GANGLION;

ACTINS; CALCIUM; CELL LINE; CELL SIZE; CYTOSKELETON; ENZYME ACTIVATION; FLUORESCENT DYES; FURA-2; GANGLIA, SPINAL; GAP-43 PROTEIN; HUMANS; HYPOTONIC SOLUTIONS; INOSITOL 1,4,5-TRISPHOSPHATE; ISOENZYMES; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE MICRODOMAINS; OSMOLAR CONCENTRATION; PHOSPHOLIPASE C; PROTEIN KINASE C; RECEPTORS, SENSORY; SIGNAL TRANSDUCTION; WATER-ELECTROLYTE BALANCE;

MAMMALIA;

EID: 0037600561     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg294     Document Type: Article

References (45)

1. Aigner, L. and Caroni, P. (1993) Depletion of 43-kDa growth-associated protein in primary sensory neurons leads to diminished formation and spreading of growth cones. J. Cell Biol., 123, 417-429.
2. Aigner, L. and Caroni, P. (1995) Absence of persistent spreading, branching and adhesion in GAP-43-depleted growth cones. J. Cell Biol., 128, 647-660.
3. Arni, S., Keilbaugh, S.A., Ostermeyer, A.G. and Brown, D.A. (1998) Association of GAP-43 with detergent-resistant membranes requires two palmitoylated cysteine residues. J. Biol. Chem., 273, 28478-28485.
4. Bomze, H.M., Bulsara, K.R., Iskandar, B.J., Caroni, P. and Pate Skene, J.H. (2001) Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons. Nature Neurosci., 4, 38-43.
5. Bourque, C.W. and Oliet, S.H.R. (1997) Osmoreceptors in the central nervous system. Annu. Rev. Physiol., 59, 601-619.
6. Cabedo, H., Luna, C., Fernández, A.M., Gallar, J. and Ferrer-Montiel, A. (2002) Molecular determinants of the sensory and motor neuron derived factor insertion into plasma membrane. J. Biol. Chem., 277, 19905-19912.
7. Caprini, M., Ferroni, S., Planells-Cases, R., Rueda, J., Rapisarda, C., Ferrer-Montiel, A.V. and Montal, M. (2001) Structural adaptability between the putative voltage sensor of Kv channels and the prokaryotic KcsA channel. J. Biol. Chem., 276, 21070-21076.
8. 2 rafts. EMBO J., 20, 4332-4336.
9. Chada, S., Lamoureux, P., Buxbaum, R.E. and Heidemann, S.R. (1997) Cytomechanics of neurite outgrowth from chick brain neurons. J. Cell Sci., 110, 1179-1186.
10. Chao, S., Benowitha, L.I., Krainc, D. and Irwin, N. (1996) Use of a two-hybrid system to investigate molecular interactions of GAP-43. Mol. Brain Res., 40, 195-202.
11. Colbert, H.A., Smith, T.L. and Bargmann, C.I. (1997) OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation and olfactory adaptation in Caenorhabditis elegans. J. Neurosci., 17, 8259-8269.
12. 2+ stores in rat sympathetic neurons. Proc. Natl Acad. Sci. USA, 95, 7151-7156.
13. Dent, E.W. and Meiri, K.F. (1998) Distribution of phosphorylated GAP-43 (neuromodulin) in growth cones directly reflects growth cone behavior. J. Neurobiol., 35, 287-299.
14. h (transglutaminase II)-mediated signaling. J. Biol. Chem., 271, 16451-16454.
15. Fournier, A.E. and Strittmatter, S.M. (2002) Regenerating nerves follow the road more traveled. Nat. Neurosci., 5, 821-822.
16. Gamby, C., Waage, M.C., Allen, R.G. and Baizer, L. (1996) Analysis of the role of calmodulin binding and sequestration in neuromodulin (GAP-43) function. J. Biol. Chem., 271, 26698-26705.
17. García-Añoveros, J. and Corey, D.P. (1997) The molecules of mechanosensation. Annu. Rev. Neurosci., 20, 567-594.
18. Gillespie, P.G. and Walker, R.G. (2001) Molecular basis of mechanosensory transduction. Nature, 413, 194-202.
19. Goldberg, D.J. and Grabham, P.W. (1999) Braking news: calcium at the growth cone. Neuron, 22, 423-425.
20. Gomez, T.M. and Spitzer, N.C. (1999) In vivo regulation of axon extension and pathfinding by growth-cone calcium transients. Nature, 397, 350-355.
21. Hamill, O.P. and Martinac, B. (2001) Molecular basis of mechanotransduction in living cells. Physiol. Rev., 81, 685-740.
22. Hart, A.C., Kass, J., Shapiro, J.E. and Kaplan, J.M. (1999) Distinct signaling pathways mediate touch and osmosensory responses in a polymodal sensory neuron. J. Neurosci., 19, 1952-1956.
23. Heidemann, S.R. and Buxbaum, R.E. (1994) Mechanical tension as a regulator of axonal development. Neurotoxicology, 15, 95-107.
24. Hulo, S., Alberi, S., Laux, T., Mueller, D. and Caroni, P. (2002) A point mutant of GAP-43 induces enhanced short-term and long term hippocampal plasticity. Eur. J. Neurosci., 15, 1976-1982.
25. Janmey, P.A. (1998) The cytoskeleton and cell signaling: component localization and mechanical coupling. Physiol. Rev., 78, 763-781.
26. 2 at plasmalemmal rafts and regulate cell cortex actin dynamics through a common mechanism. J. Cell Biol., 149, 1455-1471.
27. Liedtke, W., Choe, Y., Martí-Renom, M.A., Bell, A.M., Denis, C.S., Sali, A., Hudspeth, A.J., Friedman, J.M. and Heller, S. (2000) Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell, 103, 525-535.
28. Maier, D.L., Shyamala, M., Donovan, S.L., Soppet, D., Tessarollo, L., McCasland, J.S. and Meiri, K.F. (1999) Disrupted cortical map and absence of cortical barrels in growth-associated protein (GAP)-43 knockout mice. Proc. Natl Acad. Sci. USA, 96, 9397-9402.
29. Mueller, B.K. (1999) Growth cone guidance: first steps towards a deeper understanding. Annu. Rev. Neurosci., 22, 351-388.
30. Muto, Y., Nagao, T. and Urushidani, T. (1997) The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell. J. Pharmacol. Exp. Ther., 282, 1379-1388.
31. Nakamura, F., Strittmatter, P. and Strittmatter, S.M. (1998) GAP-43 augmentation of G-protein mediated signal transduction is regulated by both phosphorylation and palmitoylation. J. Neurochem., 70, 983-992.
32. Neve, R.L., Coopersmith, R., Mcphie, D.L., Santeufemio, C., Pratt, K.G., Murphy, C.J. and Lynn, S.D. (1998). The neuronal growth-associated protein GAP-43 interacts with rabaptin-5 and participates in endocytosis. J. Neurosci., 18, 7757-7767.
33. Nguyen, Q.T., Sanes J.R. and Lichtman, J.W. (2002) Pre-existing pathways promote precise projection patterns. Nat. Neurosci., 5, 861-867.
34. Qin, H., Dent, E.W. and Meiri, K.F. (1997) Modulation of acting filament behavior by GAP-43 (neuromodulin) is dependent on the phosphorylation status of serine 41, the protein kinase C site. J. Neurosci., 17, 3515-3524.
35. Rhee, S.G. (2001) Regulation of phosphoinositide-specific phospholipase C. Annu. Rev. Biochem., 70, 281-312.
36. Shen, Y., Mani, S., Donovan, S.L., Schwob, J.E. and Meiri, K.F. (2002) Growth-associated protein-43 is required for commissural axon guidance in the developing vertebrate nervous system. J. Neurosci., 22, 239-247.
37. 2+ from different intracellular pools. Biochem. J., 351, 683-686.
38. Strotmann, R., Harteneck, C., Nunnenmacker, K., Schultz, G. and Plant, T.D. (2000) OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat. Cell Biol., 2, 695-702.
39. Suh, B.-C. and Hille, B. (2002) Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis. Neuron, 35, 507-520.
40. Suzuki, M., Sato, J., Kutsuwada, K., Ooki, G. and Imai M. (1999) Cloning of a stretch-inhibitable nonselective cation channel. J. Biol. Chem., 274, 6330-6336.
41. Tejero-Diez, P., Rodríguez-Sanchez, P., Martin-Cofreces, N.B. and Diez-Guerra, F.J. (2000) bFGF stimulates GAP-43 phosphorylation at ser41 and modifies its intracellular localization in cultured hippocampal neurons. Mol. Cell. Neurosci., 16, 766-780.
42. Viana, F., de la Peña, E., Pecson, B., Schmidt, R.F. and Belmonte, C. (2001) Swelling-activated calcium signaling in cultured mouse primary sensory neurons. Eur. J. Neurosci., 13, 722-734.
43. Walker, R.G., Willingham, A.T. and Zucker, C.S. (2000) A Drosophila mechanosensory transduction channel. Science, 287, 2229-2234.
44. Widmer, F. and Caroni, P. (1993) Phosphorylation-site mutagenesis of the growth-associated protein GAP-43 modulates its effects on cells spreading and morphology. J. Cell Biol., 120, 503-512.
45. Zheng, J., Lamoureux, P. Dennerll, S.V., Buxbaum R.E. and Heidemann, S.R. (1991) Tensile regulation of axonal elongation and initiation. J. Neurosci., 11, 1117-1125.