Transgenic and knock-out mouse pups: The growing need for behavioral analysis

Genes, Brain and Behavior

Volumn 1, Issue 3, 2002, Pages 135-141

  Branchi, I ^a   Ricceri, L ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Behavior; Compensatory mechanisms; Development; Genetically modified; Mouse; Pup

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL MODEL; AVERSIVE BEHAVIOR; BEHAVIOR; CENTRAL NERVOUS SYSTEM; COGNITION; DEVELOPMENTAL DISORDER; DNA MODIFICATION; GENETIC MANIPULATION; KNOCKOUT MOUSE; LEARNING; MAZE TEST; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; ONTOGENY; OPEN FIELD BEHAVIOR; PASSIVE AVOIDANCE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; REVIEW; SENSORIMOTOR FUNCTION; SPATIAL MEMORY; SUCKLING; TRANSGENIC MOUSE;

ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; BRAIN; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, GENETIC; NEURONAL PLASTICITY;

ANIMALIA; MUS MUSCULUS;

EID: 0037565073     PISSN: 16011848     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1601-183X.2002.10301.x     Document Type: Review

References (68)

1. Alleva, E., Aloe, L. & Laviola, G. (1986) Pretreatment of young mice with nerve growth factor enhances scopolamine-induced hyperactivity. Brain Res 393, 278-281.
2. Alleva, E. & Calamandrei, G. (1986) Odor-aversion learning and retention span in neonatal mouse pups. Behav Neural Biol 46, 348-357.
3. Altafaj, X., Dierssen, M., Baamonde, C., Marti, E., Visa, J., Guimera, J., Oset, M., Gonzalez, J.R., Florez, J., Fillat, C. & Estivill, X. (2001) Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome. Hum Mol Genet 10, 1915-1923.
4. Bakker, C.E., Verheij, C., Willemsen, R., van der Helm, R., Oerlemans, F., Vermey, M., Bygrave, A., Hoogeveen, A.T., Oostra, B.A., Reyniers, E., De Boulle, D., D'Hooge, R., Cras, P., van Velzen, D., De Deyn, P.P., Darby, J.K. & Willems, P.J. (1994) Fmr 1 knockout mice: a model to study fragile X mental retardation. Cell 78, 23-33.
5. Bateson, P. (1981) Ontogeny of behaviour. Br Med Bull 37, 159-164.
6. Bendotti, C., Hohmann, C., Forloni, G., Reeves, R., Coyle, J.T. & Oster-Granite, M.L. (1990) Developmental expression of somatostatin in mouse brain. II. In situ hybridization. Brain Res Dev Brain Res 53. 26-39.
7. Bignami, G. (1996) Economical test methods for developmental neurobehavioral toxicity. Environ Health Perspect 104, 285-298.
8. Blue, M.E., Erzurumlu, R. S. & Jhaveri, S. (1991) A comparison of pattern formation by thalamocortical and serotonergic afferents in the rat barrel field cortex. Cereb Cortex 1, 380-389
9. Bosse, R., Fumagalli, F., Jaber, M., Giros, B., Gainetdinov, R.R., Wetsel, W.C., Missale, C. & Caron, M.G. (1997) Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter Neuron 19, 127-138.
10. Branchi, I., Santucci, D. & Alleva, E. (2001) Ultrasonic vocalisation emitted by infant rodents: a tool for assessment of neurobehavioural development. Behav Brain Res 125, 49-56.
11. Brunner, D., Buhot, M.C., Hen, R. & Hofer, M. (1999) Anxiety, motor activation, and maternal-infant interactions in 5HT1B knockout mice. Behav Neurosci 113, 587-601.
12. Calamandrei, G., Valanzano, A. & Alleva, E. (1991) NGF and cholinergic control of behavior: anticipation and enhancement of scopolamine effects in neonatal mice. Brain Res Dev Brain Res 61, 237-241.
13. Calamandrei, G., Ricceri, L. & Valanzano, A. (1996) Systemic administration of anti-NGF antibodies to neonatal mice impairs 24-h retention of an inhibitory avoidance task while increasing ChAT immunoreactivity in the medial septum Behav Brain Res 78, 81-91.
14. Chapillon, P. & Roullet, P. (1996) Use of proximal and distal cues in place navigation by mice changes during ontogeny. Dev Psychobiol 29, 529-545.
15. Chapillon, P., Roullet, P. & Lassalle, J.M. (1995) Ontogeny of orientation and spatial learning on the radial maze in mice. Dev Psychobiol 28, 429-442.
16. Chiang, M.Y., Misner, D., Kempermann, G., Schikorski, T., Giguere, V., Sucov, H.M., Gage, F.H., Stevens, C.F. & Evans, R.M. (1998) An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. Neuron 21, 1353-1361.
17. Cirulli, F., Adriani, N. & Laviola, G., (1997) Sexual segregation in infant mice: behavioural and neuroendocrine responses to d-amphetamine administration Psychopharmacology (Berl) 134, 140-152.
18. Crawley, J.N. (2000) What's Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice. Wiley-Liss, New York.
19. Cuomo, V., De Salvia, M.A., Petruzzi, S. & Alleva, E. (1996) Appropriate end points for the characterization of behavioral changes in developmental toxicology. Environ Health Perspect 104, 307-315.
20. Darmani, N.A. & Ahmad, B. (1999) Long-term sequential determination of behavioral ontogeny of 5-HT1A and 5-HT2 receptor functions in the rat. J Pharmacol Exp Ther 288, 247-253.
21. Espinosa, F., Mcmahon, A., Chan, E., Wang, S., Ho, C.S., Heintz, N. & Joho, R.H. (2001) Alcohol hypersensitivity, increased locomotion, and spontaneous myoclonus in mice lacking the potassium channels Kv3.1 and Kv3.3. J Neurosci 21, 6657-6665
22. Eva, C., Fusco, M., Brusa, R., Schiavo, N., Ricci Gamalero, S., Vantini, G. & Genazzani, E. (1994) Intracerebroventricular administration of nerve growth factor affects muscarinic cholinergic receptors in the cerebral cortex of neonatal rats. Neurochem Int 24, 57-65.
23. Fernandez-Ruiz, J., Berrendero, F., Hernandez, M.L. & Ramos, J.A. (2000) The endogenous cannabinoid system and brain development. Trenos Neurosci 23, 14-20
24. Fox, W.M. (1965) Reflex-ontogeny and behavioral development of the mouse. Anim Behav 13, 234-240.
25. Gingrich, J.A. & Hen, R. (2000) The broken mouse: the role of development, plasticity and environment in the interpretation of phenotypic changes in knockout mice. Curr Opin Neurobiol 10, 146-152.
26. Grant, S.G., O'Dell, T.J., Karl, K.A., Stein, P.L., Soriano, P. & Kandel, E.R. (1992) Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science 258, 1903-1910.
27. Greenough, WT., Klintsova, A.Y., Irwin, S.A., Galvez, R., Bates, K.E. & Weiler, I.J. (2001) Synaptic regulation of protein synthesis and the fragile X protein. Proc Natl Acad Sci U S A 98, 7101-7106.
28. Guy, J., Hendrich, B., Holmes, M., Martin, J.E. & Bird, A. (2001) A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 27, 322-326
29. Hohmann, C.F. & Berger-Sweeney, J. (1998) Cholinergic regulation of cortical development and plasticity. New twists to an old story. Perspect Dev Neurobiol 5, 401-425.
30. Hohmann, C.F., Richardson, C., Pitts, E. & Berger-Sweeney, J. (2000) Neonatal 5,7-DHT lesions cause sex-specific changes in mouse cortical morphogenesis. Neural Plast 7, 213-232.
31. Holtzman, D.M., Santucci, D., Kilbridge, J., Chua-Couzens, J., Fontana, D.J., Daniels, S.E., Johnson, R.M., Chen, K., Sun, Y, Carlson, E., Alleva, E., Epstein, C.J. & Mobley, W.C. (1996) Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome. Proceedings of the Natl Acad Sci USA 93, 13333-13338.
32. Johnson, J. & Oppenheim, R. (1994) Neurotrophins. Keeping track of changing neurotrophic theory. Curr Biol 4, 662-665
33. Krasnegor, N., Blass, E., Hofer, M. & Smotherman, W. (1987) Perinatal Development: a Psychobiological Perspective. Academic Press, Orlando, FL.
34. Lauder, J.M. (1993) Neurotransmitters as growth regulatory signals: role of receptors and second messengers. Trends Neurosci 16, 233-240.
35. Laviola, G., Renna, G., Bignami, G. & Cuomo, V (1988) Ontogenetic and pharmacological dissociation of various components of locomotor activity and habituation in the rat. Int J Dev Neurosci 6, 431-438.
36. Laviola, G., Terranova, M.L., Sedowofia, K., Clayton, R. & Manning, A. (1994) A mouse model of early social interactions after prenatal drug exposure: a genetic investigation, Psychopharmacology (Berl) 113, 388-394.
37. Levitt, P., Barbe, M.F. & Eagleson, K.L. (1997) Patterning and specification of the cerebral cortex. Annu Rev Neurosci 20, 1-24.
38. Lipp, H.P. & Wahlsten, D. (1992) Absence of the corpus callosum. In Driscoll, P., (ed) Genetically Defined Animal Models of Neuro-Behavioural Dysfunction. Birkhäuser, Boston, pp. 217-252.
39. Livy, D.J., Schalomon, P.M., Roy, M., Zacharias, M.C., Pimenta, J., Lent, R. & Wahlsten, D. (1997) Increased axon number in the anterior commissure of mice lacking a corpus callosum. Exp Neurol 146, 491-501
40. Montkowski, A. & Holsboer, F. (1997) Intact spatial learning and memory in transgenic mice with reduced BDNF. Neuroreport 8, 779-782.
41. Nagy, Z.M., Thaller, K. & Mazzaferri, T.A. (1977) Acquisition and retention of a passive-avoidance task as a function of age in mice. Dev Psychobiol 10, 563-573.
42. Pappas, B.A., Davidson, C.M., Fortin, T., Nallathamby, S., Park, G.A., Mohr, E. & Wiley, R.G. (1996) 192 IgG-saporin lesion of basal forebrain cholinergic neurons in neonatal rats. Brain Res Dev Brain Res 96, 52-61.
43. Paylor, R., Baskall-Baldini, L., Yuva, L. & Wehner, J.M. (1996) Developmental differences in place-learning performance between C57BL/6 and DBA/2 mice parallel the ontogeny of hippocampal protein kinase C. Behav Neurosci 110, 1415-1425.
44. Paylor, R., Hirotsune, S., Gambello, M.J., Yuva-Paylor, L., Crawley, J.N. & Wynshaw-Boris, A. (1999) Impaired learning and motor behavior in heterozygous Pafah1b1 (Lis1) mutant mice. Learn Mem 6, 521-537.
45. Ricceri, L., Calamandrei, G. & Berger-Sweeney, J. (1997) Different effects of postnatal day 1 versus 7 192 immunoglobulin G-saporin lesions on learning, exploratory behaviors, and neurochemistry in juvenile rats. Behav Neurosci 111, 1292-1302
46. Ricceri, L., Colozza, C. & Calamandrei, G. (2000) Ontogeny of spatial discrimination in mice: a longitudinal analysis in the modified open-field with objects. Dev Psychobiol 37, 109-11B.
47. Ricceri, L., Usiello, A., Valanzano, A., Calamandrei, G., Frick, K. & Berger-Sweeney, J (1999) Neonatal 192 IgG-saporin lesions of basal forebrain cholinergic neurons selectively impair response to spatial novelty in adult rats. Behav Neurosci 113, 1204-1215.
48. Ricceri, L., Venerosi, A., Valanzano, A., Sorace, A. & Alleva, A. (2001) Prenatal AZT or 3TC and mouse development of locomotor activity and hotplate responding upon administration of the GABA(A) receptor agonist muscimol. Psychopharmacology (Berl) 153, 434-442.
49. Robertson, R.T., Gallardo, K.A., Claytor, K.J., Ha, D.H., Ku, K.H., Yu, B.P., Lauterborn, J.C. & Wiley, R.G., Yu, J., Gall, C.M. & Leslie, F.M. (199B) Neonatal treatment with 192 IgG-saporin produces long-term forebrain cholinergic deficits and reduces dendritic branching and spine density of neocortical pyramidal neurons Cereb Cortex 8, 142-155.
50. Routtenberg, A., Cantallops, I., Zaffuto, S., Serrano, P. & Namgung, U. (2000) Enhanced learning after genetic overexpression of a brain growth protein. Proc Natl Acad Sci U S A 97, 7657-7662.
51. Rudy, J.W. (1993) Contextual conditioning and auditory cue conditioning dissociate during development. Behav Neurosci 107, 887-891.
52. Rudy, J.W. & Morledge, P. (1994) Ontogeny of contextual fear conditioning in rats: implications for consolidation, infantile amnesia, and hippocampal system function. Behav Neurosci 108, 227-234.
53. Saunders, R.C., Kolachana, B.S., Bachevalier, J. & Weinberger, D.R. (1998) Neonatal lesions of the medial temporal lobe disrupt prefrontal cortical regulation of striatal dopamine. Nature 393, 169-171.
54. Scott, J.P. (1953) The development of social behavior patterns in the mouse, in relation to natural periods. Behaviour 6, 35-65.
55. Scott, J.P. (1962) Critical periods in behavioral development. Science 138, 949-958.
56. Shair, H.N., Barr, G.A. & Hofer, M.A. (1991) Developmental Psychobiology. Oxford University Press, New York.
57. Son, H., Hawkins, R.D., Martin, K., Kiebler, M., Huang, P.L., Fishman, M.C. & Kandel, E.R. (1996) Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase. Cell 87, 1015-1023.
58. Spear, L.P. (1990) Neurobehavioral assessment during the early postnatal period. Neurotoxicol Teratol 12, 489-495.
59. Terranova, M.L., Laviola, G. & Alleva, E. (1993) Ontogeny of amicable social behavior in the mouse: gender differences and ongoing isolation outcomes. Dev Psychobiol 26, 467-481
60. Terranova, M.L., Laviola, G., de Acetis, L. & Alleva, E. (1998) A description of the ontogeny of mouse agonistic behavior. J Comp Psychol 112, 3-12.
61. Tremml, P., Lipp, H.P., Muller, U., Ricceri, L. & Wolfer, D.P. (1998) Neurobehavioral development, adult openfield exploration and swimming navigation learning in mice with a modified beta-amyloid precursor protein gene. Behav Brain Res 95, 65-76.
62. Villar, M.J., Hokfelt, T. & Brown, J.C. (1989) Somatostatin expression in the cerebellar cortex during postnatal development. An immunohistochemical study in the rat. Unawed Embryol 179, 257-267.
63. Vitalis, T., Cases, O., Callebert, J., Launay, J.M., Price, D.J., Seif, I. & Gaspar, P. (1998) Effects of monoamine oxidase A inhibition on barrel formation in the mouse somatosensory cortex: determination of a sensitive developmental period. J Comp Neurol 393, 169-184.
64. Wahlsten, D. (1974) A developmental time scale for postnatal changes in brain and behavior of B6D2F2 mice. Brain Res 72, 251-264.
65. Walsh, T.J. & Tilson, H.A. (1986) The use of pharmacological challanges. In Annau, Z., (ed.) Neurobehavioral Toxicology. Johns Hopkins Press, Baltimore, pp. 999-1006.
66. Weiss, E.R., Maness, P. & Lauder, J.M. (1998) Why do neurotransmitters act like growth factors? Perspect Dev Neurobiol 5, 323-335.
67. Winslow, J.T., Hearn, E.F., Ferguson, J., Young, L.J., Matzuk, M.M. & Insel, T.R. (2000) Infant vocalization, adult aggression, and fear behavior of an oxytocin null mutant mouse. Horm Behav 37 145-155.
68. Zeyda, T., Diehl, N., Paylor, R., Brennan, M.B. & Hochgeschwender, U. (2001) Impairment in motor learning of somatostatin null mutant mice. Brain Res 906, 107-114.