Neonatal treatment with 192 IgG-saporin produces long-term forebrain cholinergic deficits and reduces dendritic branching and spine density of neocortical pyramidal neurons

Cerebral Cortex

Volumn 8, Issue 2, 1998, Pages 142-155

  Robertson, Richard T ^a   Gallardo, Kathy A ^a   Claytor, Kimberly J ^a   Ha, Dun H ^a   Ku, Ko Hsiu ^a   Yu, Benjamin P ^a   Lauterborn, Julie C ^a   Wiley, Ronald G ^b   Yu, Jen ^a   Gall, Christine M ^a   Leslie, Frances M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINE ACETYLTRANSFERASE; CHOLINERGIC RECEPTOR; SAPORIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SIZE; CHOLINERGIC TRANSMISSION; ENZYME ACTIVATION; ENZYME ACTIVITY; FOREBRAIN; HISTOCHEMISTRY; IN SITU HYBRIDIZATION; NEOCORTEX; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

ACETYLCHOLINESTERASE; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, MONOCLONAL; AXONS; CELL COUNT; CELL SIZE; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC AGENTS; CHOLINERGIC FIBERS; DENDRITES; IMMUNOTOXINS; N-GLYCOSYL HYDROLASES; PROSENCEPHALON; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; THALAMUS; VISUAL CORTEX;

EID: 17344364726     PISSN: 10473211     EISSN: None     Source Type: Journal    
DOI: 10.1093/cercor/8.2.142     Document Type: Article

References (27)

1. Annis CM, Robertson RT, O'Dowd DK (1993) Aspects of early postnatal development of cortical neurons that proceed independently of normally present extrinsic influences. J Neurobiol 24:1460-1480.
2. Annis CM, O'Dowd DK, Robertson RT (1994) Activity dependent regulation of dendritic spine density on cortical pyramidal neurons in organotypic slice cultures. J Neurobiol 25:1483-1493.
3. Armstrong DM, Bruce G, Hersh LB, Gage FH (1987) Development of cholinergic neurons in the septal/diagonal band complex of the rat. Dev Brain Res 36:249-256.
4. Armstrong JN, Pappas BA (1991) The histopathological, behavioral and neurochemical effects of intraventricular injection of ethylcholine mustard aziridinium (AF64A) in the neonatal rat. Dev Brain Res 61:249-257.
5. 2+/calmodulin protein kinase gene expression in the rat central nervous system. Neuroscience 46:825-49.
6. Bigl V, Woolf NJ, Butcher LL (1982) Cholinergic projections from the basal forebrain of frontal, parietal, temporal, occipital and cingulate cortices: a combined fluorescent tracer and acetylcholinesterase analysis. Brain Res Bull 8:727-749.
7. Bock GR, Cardew G (1995) Development of the cerebral cortex, Ciba Foundation Symposium 193. New York: Wiley.
8. Book AA, Wiley RG, Schweitzer JB (1994) 192 IgG-saporin: I. specific lethality for cholinergic neurons in the basal forebrain of the rat. J Neurpathol Exp Neurol 53:95-102.
9. Bothwell M (1995) Functional interactions of neurotrophins and neurotrophin receptors. Annu Rev Neurosci 18:223-53.
10. Brady DR, Phelps PE, Vauglm JE (1989) Neurogenesis of basal forebrain cholinergic neurons in rat. Dev Brain Res 47:81-92.
11. Brice A, Berrard S, Raynaud B, Ansieau S, Coppola T, Weber MJ, Mallet J (1989) Complete sequence of a cDNA encoding an active rat choline acetyltransferase: a tool to investigate the plasticity of cholinergic phenotype expression. J Neurosci Res 23:266-73.
12. Calarco CA, Robertson RT (1995) Development of basal forebrain projections to cerebral cortex: DiI studies in rats. J Comp Neurol 354:608-626.
13. ntr decide? Neuron 18:187-190.
14. Carughi A, Carpenter KJ, Diamond MC (1990) The developing cerebral cortex: nutritional and environmental influences. In: Malnutrition and the infant brain (van Gelder NM, Butterworth RF, Drujan BD, eds), pp. 127-139, New York: Wiley-Liss.
15. Chao MV (1994) The p75 neurotrophin receptor. J Neurobiol 25:1373-85.
16. Chao MV, Hempstead BL (1995) p75 and Trk: a two-receptor system. Trends Neurosci 18:321-6.
17. Cordero ME, D'Acuna E, Benveniste S, Prado R, Nunez JA, Colombo M. (1993) Dendritic development in neocortex of infants with early postnatal life undernutrition. Pediatr Neurol 9:457-464.
18. Coyle JT, Yamamura HI (1976) Neurochemical aspects of the ontogenesis of cholinergic neurons in the rat brain. Brain Res 118:429-440.
19. Coyle JT, Price DL, DeLong MR (1983) Alzheimer's disease: a disorder of cortical cholinergic innervation. Science 219:1184-1190.
20. Cullen KM, Halliday GM, Double KL, Brooks WS, Creasey H, Broe GA (1997) Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease. Neuroscience 78: 641-652.
21. Curtis R, Adryan KM, Stark JL, Park JS, Compton DL, Weskamp G, Huber IJ, Chao MV, Jaenisch R, Lee KF et al. (1995) Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins. Neuron 14:1201-11.
22. DeFelipe J, Farinas I (1992) The pyramidal neuron of the cerebral cortex: morphological and chemical characteristics of the synaptic inputs. Progr Neurobiol 39:563-607.
23. Dinopoulos A, Eadie LA, Dori I, Parnavelas JG (1989) The development of basal forebrain projections to the rat visual cortex. Exp Drain Res 76:563-571.
24. Divac I (1975) Magnocellular nuclei of the basal forebrain project to neocortex, brain stem, and olfactory bulb. Review of some functional correlates. Brain Res 93:385-398.
25. Dori I, Parnavelas JG (1989) The cholinergic innervation of the rat cerebral cortex shows two distinct phases in development. Exp Brain Res 76:417-423.
26. Ebersole P, Parnavelas JG, Blue ME (1981) Development of the visual cortex of rats treated with 6-hydroxydopamine in early life. Anat Embryol 162:489-492.
27. Erlander MG, Tobin AJ (1991) The structural and functional heterogeneity of glutamic acid decarboxylase: a review. Neurochem Res 16:215-26.