Expression of ΔNp63 in response to phorbol ester in human limbal epithelial cells expanded on intact human amniotic membrane

Investigative Ophthalmology and Visual Science

Volumn 44, Issue 7, 2003, Pages 2959-2965

  Hernandez Galindo, Elias E ^a   Theiss, Carsten ^b   Steuhl, Klaus P ^a   Meller, Daniel ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 43; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; PLASTIC; PROTEIN P63;

ADULT; AMNION; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CORNEA EPITHELIUM; CORNEA LIMBUS; EPITHELIUM CELL; HUMAN; HUMAN TISSUE; LASER MICROSCOPY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

ADULT; AMNION; CARCINOGENS; CELLS, CULTURED; CONNEXIN 43; DNA-BINDING PROTEINS; EPITHELIAL CELLS; EPITHELIUM, CORNEAL; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; LIMBUS CORNEAE; MICROSCOPY, CONFOCAL; MIDDLE AGED; STEM CELLS; TETRADECANOYLPHORBOL ACETATE;

EID: 0037562770     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.02-0776     Document Type: Article

References (50)

1. Irwin MS, Kaelin WG. p53 family update: p73 and p63 develop their own identities. Cell Growth Diff. 2001;12:337-349.
2. Strano S, Rossi M, Fontemaggi G, et al. From p63 to p53 across p73. FEBS Lett. 2001;490:163-170.
3. Flores ER, Tsai KY, Crowley D, et al. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature. 2002;416:560-564.
4. Liefer KM, Koster MI, Wang XJ, et al. Down-regulation of p63 is required for epidermal UV-B-induced apoptosis. Cancer Res. 2000;60:4016-4020.
5. Yang A, Kaghad M, Wang Y, et al. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell. 1998;2:305-316.
6. Yang A, Schweitzer R, Sun D, et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature. 1999;398:714-718.
7. Parsa R, Yang A, McKeon F, Green H. Association of p63 with proliferative potential in normal and neoplastic human keratinocytes. J Invest Dermatol. 1999;113:1099-1105.
8. Bamberger C, Pollet D, Schmale H. Retinoic acid inhibits down-regulation of DeltaNp63alpha expression during terminal differentiation of human primary keratinocytes. J Invest Dermatol. 2002;118:133-138.
9. Noszczyk BH, Majewski ST. p63 expression during normal cutaneous wound healing in humans. Plast Reconstr Surg. 2001;108:1242-1247.
10. Di Como CJ, Urist MJ, Babayan I, et al. p63 expression profiles in human normal and tumor tissues. Clin Cancer Res. 2002;8:494-501.
11. Pellegrini G, Dellambra E, Golisano O, et al. p63 identifies keratinocyte stem cells. Proc Natl Acad Sci USA. 2001;98:3156-3161.
12. Lehrer MS, Sun TT, Lavker RM. Strategies of epithelial repair: modulation of stem cell and transit amplifying cell proliferation. J Cell Sci. 1998;111:2867-2875.
13. Potten CS, Loeffler M. Stem cells: attributes, cycles, spirals, pitfalls and uncertainties: lessons for and from the crypt. Development. 1990;110:1001-1020.
14. Lavker RM, Sun TT. Epidermal stem cells. J Invest Dermatol. 1983;81:121S-127S.
15. Schermer A, Galvin S, Sun T-T. Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol. 1986;103:49-62.
16. Cotsarelis G, Cheng SZ, Dong G, et al. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell. 1989;57:201-209.
17. Tseng SCG. Regulation and clinical implications of corneal epithelial stem cells. Mol Biol Rep. 1996;23:47-58.
18. Lavker RM, Sun TT. Epidermal stem cells: properties, markers, and location. Proc Natl Acad Sci USA. 2000;97:13473-13475.
19. Dua HS, Azuara-Blanco A. Limbal stem cells of the corneal epithelium. Surv Ophthalmol. 2000;44:415-425.
20. Daniels JT, Dart JK, Tuft SJ, Khaw PT. Corneal stem cells in review. Wound Repair Regen. 2001;9:483-494.
21. Barrandon Y, Green H. Three clonal types of keratinocytes with different capacities for multiplication. Proc Natl Acad Sci USA. 1987;84:2302-2306.
22. Pellegrini G, Golisano O, Paterna P, et al. Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface. J Cell Biol. 1999;145:769-782.
23. Yuspa SH, Ben T, Hennings H. The induction of epidermal transglutaminase and terminal differentiation by tumor promoters in cultured epidermal cells. Carcinogenesis. 1983;4:1413-1418.
24. Yuspa SH, Ben T, Hennings H, Lichti U. Divergent responses in epidermal basal cells exposed to the tumor promoter 12-Otetradecanoylphorbol-13-acetate. Cancer Res. 1982;42:2344-2349.
25. Kruse FE, Tseng SCG. A tumor promoter-resistant subpopulation of progenitor cells is present in limbal epithelium more than corneal epithelium. Invest Ophthalmol Vis Sci. 1993;34:2501-2511.
26. Lavker RM, Wei ZG, Sun TT. Phorbol ester preferentially stimulates mouse fornical conjunctival and limbal epithelial cells to proliferate in vivo. Invest Ophthalmol Vis Sci. 1998;39:301-307.
27. Tseng SCG, Sun T-T. Stem cells: ocular surface maintenance. In: Brightbill FS, ed. Corneal Surgery: Theory, Technique, and Tissue. 3rd ed. St. Louis: Mosby; 1999:chap. 2.
28. Tseng SCG. Conjunctival grafting for corneal diseases. In: Tasman W, Jaeger EA, eds. Duane's Clinical Ophthalmology. Vol 6. Philadelphia: JB Lippincott; 1994:chap. 34.
29. Holland EJ, Schwartz GS. The evolution of epithelial transplantation for severe ocular surface disease and a proposed classification system. Cornea. 1996;15:549-556.
30. Holland EJ. Epithelial transplantation for the management of severe ocular surface disease. Trans Am Ophthalmol Soc. 1996;94:677-743.
31. Pellegrini G, Traverso CE, Franzi AT, et al. Long-term restoration of damaged corneal surface with autologous cultivated corneal epithelium. Lancet. 1997;349:990-993.
32. Tsai RJF, Li L-M, Chen J-K. Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. N Engl J Med. 2000;343:86-93.
33. Schwab IR, Reyes M, Isseroff RR. Successful transplantation of bioengineered tissue replacements in patients with ocular surface disease. Cornea. 2000;19:421-426.
34. Koizumi N, Fullwood NJ, Bairaktaris G, et al. Cultivation of corneal epithelial cells on intact and denuded human amniotic membrane. Invest Ophthalmol Vis Sci. 2000;41:2506-2513.
35. Koizumi N, Inatomi T, Suzuki T, et al. Cultivated corneal epithelial transplantation for ocular surface reconstruction in acute phase of Stevens-Johnson syndrome. Arch Ophthalmol. 2001;119:298-300.
36. Koizumi N, Inatomi T, Suzuki T, et al. Cultivated corneal epithelial stem cell transplantation in ocular surface disorders. Ophthalmology. 2001;108:1569-1574.
37. Rama P, Bonini S, Lambiase A, et al. Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. Transplantation. 2001;72:1478-1485.
38. Meller D, Pires RT, Tseng SC. Ex vivo preservation and expansion of human limbal epithelial stem cells on amniotic membrane cultures. Br J Ophthalmol. 2002;86:463-471.
39. Grueterich M, Espana E, Tseng SCG. Connexin 43 expression and proliferation of human limbal epithelium on intact and denuded amniotic membrane. Invest Ophthalmol Vis Sci. 2002;43:63-71.
40. Han B, Schwab IR, Madsen TK, Isseroff RR. A fibrin-based bioengineered ocular surface with human corneal epithelial stem cells. Cornea. 2002;21:505-510.
41. Koizumi N, Inatomi T, Quantock AJ, et al. Amniotic membrane as a substrate for cultivating limbal corneal epithelial cells for autologous transplantation in rabbits. Cornea. 2000;19:65-71.
42. Hernandez Galindo EE, Theiss C, Steuhl K-P, Meller D. Gap junctional communication in microinjected human limbal and peripheral corneal epithelial cells cultured on preserved and intact human amniotic membrane. Exp Cell Res. 2003;76:303-314.
43. Meller D, Dabul V, Tseng SCG. Expansion ofconjunctival epithelial progenitor cells on amniotic membrane. Exp Eye Res. 2002;74:537-545.
44. Tseng SCG, Prabhasawat P, Lee S-H. Amniotic membrane transplantation for conjunctival surface reconstruction. Am J Ophthalmol. 1997;124:765-774.
45. Meller D, Tseng SCG. Conjunctival epithelial cell differentiation on amniotic membrane. Invest Ophthalmol Vis Sci. 1999;40:878-886.
46. Yang A, McKeon F. P63 and P73: P53 mimics, menaces and more. Nature Review Molecular Cell Biology. 2000;1:199-207.
47. Matic M, Petrov IN, Chen S, et al. Stem cells of the corneal epithelium lack connexins and metabolite transfer capacity. Differentiation. 1997;61:251-260.
48. Wolosin JM, Xiong X, Schutte M, et al. Stem cells and differentiation stages in the limbo-corneal epithelium. Prog Retinal Eye Res. 2000;19:223-255.
49. Gallico GG, III, O'Connor NE, Compton CC, et al. Permanent coverage of large burn wounds with autologous cultured human epithelium. N Engl J Med. 1984;311:448-451.
50. Lindberg K, Brown ME, Chaves HV, et al. In vitro preparation of human ocular surface epithelial cells for transplantation. Invest Ophthalmol Vis Sci. 1993;34:2672-2679.