ATM mutations and protein expression are not associated with familial B-CLL cases

Leukemia Research

Volumn 27, Issue 10, 2003, Pages 973-975

  Ishibe, Naoko ^a   Goldin, Lynn R ^a   Caporaso, Neil E ^a   Sgambati, Maria T ^a   Dean, Michael ^b   Albitar, Maher ^c   Manshouri, Taghi ^c   Gerrard, Bernard ^b   Marti, Gerald E ^d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d Ctr Biologics Eval Res Food D   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; DNA;

ADULT; AGED; ARTICLE; B CELL LEUKEMIA; CARCINOGENESIS; CHROMOSOME DELETION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DNA DETERMINATION; FAMILIAL CANCER; FEMALE; GENE MUTATION; GENETIC SUSCEPTIBILITY; GERM CELL; HETEROZYGOTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; ONSET AGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; SOMATIC MUTATION;

EID: 0037561159     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(03)00067-5     Document Type: Letter

References (18)

1. Horowitz M. The genetics of familial leukemia. Leukemia. 11:1997;1347-1359.
2. Ishibe N., Sgambati M.T., Fontaine L., Goldin L.R., Jain N., Weissman N.et al. Clinical characteristics of familial B-CLL in the National Cancer Institute Familial Registry. Leuk. Lymphoma. 42:2001;99-108.
3. Donher H., Stilgenbauer S., James M.R., Benner A., Weilguni T., Bentz M.et al. 11q deletions identify a new subset of B-cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis. Blood. 89:1997;2516-2522.
4. Savitsky K., Bar-Shira A., Gilad S., Rotman G., Ziv Y., Vanagaite L.et al. A single ataxia-telangiectasia gene with a product similar to PI-3 kinase. Science. 268:1995;1749-1753.
5. Peterson R.D.A., Funkhouser J.D., Tuck-Muller C.M., Gatti R.A. Cancer susceptibility in ataxia-telangiectasia. Leukemia. 6(Suppl. 1):1992;8-13.
6. Morrell D., Cromartie E., Swift M. Mortality and cancer incidence in 263 patients with ataxia-telangiectasia. J. Natl. Cancer Inst. 77:1986;89-92.
7. Taylor A.M., Metcalfe J.A., Thick J., Mak Y.F. Leukemia and lymphoma in ataxia-telangiectasia. Blood. 87:1996;423-438.
8. Starostik P., Manshouri T., O'Brien S., Freireich E., Kantarjian H., Haidar M.et al. Deficiency of the ATM protein expression defines an aggressive subgroup of B-cell chronic lymphocytic leukemia. Cancer Res. 58:1998;4552-4557.
9. Vorechovsky I., Luo L., Lindblom A., Negrini M., Webster A.D., Croce C.M.et al. ATM mutations in cancer families. Cancer Res. 56:1996;4130-4133.
10. Schaffner C., Idler I., Stilgenbauer S., Dohner H., Lichter P. Mantle cell lymphoma is characterized by inactivation of the ATM gene. Proc. Natl. Acad. Sci. U.S.A. 97:2000;2773-2778.
11. Camacho E., Hernandez L., Hernandez S., Tort F., Bellosillo B., Bea S.et al. ATM gene inactivation in mantle cell lymphoma mainly occurs by truncating mutations and missense mutations involving the phosphatidylinositol-3-kinase domain and is associated with increasing numbers of chromosomal imbalances. Blood. 99:2002;238-244.
12. Schaffner C., Stilgenbauer S., Rappold G.A., Dohner H., Lichter P. Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia. Blood. 94:1999;748-753.
13. Stankovic T., Weber P., Stewart G., Behenham T., Murray J., Byrd P.J.et al. Inactivation of ataxia-telangiectasia mutated gene in B-cell chronic lymphocytic leukemia. Lancet. 353:1999;26-29.
14. Stilgenbauer S, Bullinger L, Licther P, Dohner H, the German CLL Study Group. Genetics of chronic lymphocytic leukemia. Leukemia 2002;16:993-1007.
15. Sandoval N., Platzer M., Rosehnthal A., Dork T., Bendix R., Skawran B.et al. Characterization of ATM gene mutations in 66 ataxia-telangiectasia families. Hum. Mol. Genet. 8:1999;69-79.
16. Xiao W., Oefner P.J. Denaturing high-performance liquid chromatography: a review. Hum. Mutat. 17:2001;439-474.
17. Bevan S., Catovsky D., Marossy A., Matutes E., Popat S., Antonovic P.et al. Linkage analysis for ATM in familial B-cell chronic lymphocytic leukemia. Leukemia. 13:1999;1497-1500.
18. Yuille M.R., Condie A., Hudson C.D., Bradshaw P.S., Stone E.M., Matutes E.et al. ATM mutations are rare in familial chronic lymphocytic leukemia. Blood. 100:2002;603-609.