The acute phase protein haptoglobin is locally expressed in arthritic and oncological tissues

International Journal of Experimental Pathology

Volumn 84, Issue 2, 2003, Pages 69-74

  Smeets, Mirjam B ^a,b   Fontijn, Jolanda ^a   Kavelaars, Annemieke ^a   Pasterkamp, Gerard ^a,b   De Kleijn, Dominique P V ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

Arthritis; Cancer; Expression; Haptoglobin

Indexed keywords

ACUTE PHASE PROTEIN; HAPTOGLOBIN; LIVER PROTEIN; MESSENGER RNA;

ACHILLES TENDON; ANIMAL MODEL; ANIMAL TISSUE; ANKLE; ARTHRITIS; ARTICLE; CANCER; CELL METABOLISM; CELL MIGRATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; IN SITU HYBRIDIZATION; KIDNEY TUMOR; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RAT; STROMA CELL; TISSUE LEVEL; WESTERN BLOTTING;

ANIMALS; ARTHRITIS, EXPERIMENTAL; GENE EXPRESSION; HAPTOGLOBINS; HUMANS; IN SITU HYBRIDIZATION; KIDNEY NEOPLASMS; MALE; NEOPLASM PROTEINS; RATS; RATS, INBRED LEW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0037560989     PISSN: 09599673     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2613.2003.00336.x     Document Type: Article

References (26)

1. BASHYAM M.D. (2002) Understanding cancer metastasis: an urgent need for using differential gene expression analysis. Cancer 94, 1821-1829.
2. CHOW V., KUROSKY A. & MURRAY R.K. (1984) Studies on the biosynthesis of rabbit haptoglobin. J. Biol. Chem. 259, 6622-6629.
3. COBELENS P.M., HEIJNEN C.J., NIEUWENHUIS E.E.S. ET AL. (2000) Treatment of adjuvant-induced arthritis by oral administration of mycobacterial Hsp65 during disease. Arthritis Rheum. 43, 2694-2702.
4. D'ARMIENTO J., DALAL S.S. & CHADA K. (1997) Tissue, temporal and inducible expression pattern of haptoglobin in mice. Gene 195, 19-27.
5. DAVIES B., MILES D.W., HAPPERFIELD L.C. ET AL. (1993) Activity of type IV collagenases in benign and malignant breast disease. Br. J. Cancer 67, 1126-1131.
6. FIRESTEIN G.S. (1996) Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Rheum. 39, 1781-1790.
7. HEPPNER K.J., MATRISIAN L.M., JENSEN R.A. & RODGERS W.H. (1996) Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response. Am. J. Pathol. 149, 273-282.
8. ITOH T., TANIOKA M., MATSUDA H. ET AL. (1999) Experimental metastasis is suppressed in MMP-9-deficient mice. Clin. Exp. Metastasis 17, 177-181.
9. JACKSON C., NGUYEN M., ARKELL J. & SAMBROOK P. (2001) Selective matrix metalloproteinases (MMP) inhibition in rheumatoid arthritis-targeting gelatinase A activation. Inflamm. Res. 50, 183-186.
10. DE KLEIJN D.P.V., SLUIJTER J.P.G., SMIT J. ET AL. (2001) Furin and membrane type-1 metalloproteinase mRNA levels and activation of metalloproteinase-2 are associated with arterial remodeling. FEBS Lett. 501, 37-41.
11. DE KLEIJN D.P., SMELTS M.B., KEMMEREN P.P. ET AL. (2002) Acute-phase protein haptoglobin is a cell migration factor involved in arterial restructuring. FASEB J. 16, 1123-1125.
12. LI S., CHOW L.H. & PICKERING J.G. (2000) Cell surface-bound collagenase-1 and focal substrate degradation stimulate the rear release of motile vascular smooth muscle cells. J. Biol. Chem. 275, 35384-35392.
13. LIM S.K., KIM H., LIM S.K. ET AL. (1998) Increased susceptibility in Hp knockout mice during acute hemolysis. Blood 92, 1870-1877.
14. MULLER-LADNER U., KRIEGSMANN J., FRANKLIN B.N. ET AL. (1996) Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice. Am. J. Pathol. 149, 1607-1615.
15. PILCHER B.K., DUMIN J.A., SUDBECK B.D., KRANE S.M., WELGUS H.G. & PARKS W.C. (1997) The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix. J. Cell Biol. 137, 1445-1457.
16. DA SILVA CORREIA J. & ULEVITCH R.J. (2002) MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor. J. Biol. Chem. 277, 1845-1854.
17. SINGER I.I., KAWKA D.W., BAYNE E.K. ET AL. (1995) VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis. J. Clin. Invest. 95, 2178-2186.
18. SMEETS M.B., PASTERKAMP G., LIM S.K., VELEMA E., VAN MIDDELAAR B. & DE KLEIJN D.P.V. (2002) Nitric oxide synthesis is involved in arterial haptoglobin expression after sustained flow changes. FEBS Lett. 529, 221-224.
19. THOMPSON S., KELLY C.A., GRIFFITHS I.D. & TURNER G.A. (1989) Abnormally-fucosylated serum haptoglobin in patients with inflammatory joint disease. Clin. Chim. Acta. 184, 251-258.
20. THOMPSON S., CANTWELL B.M., CORNELL C. & TURNER G.A. (1991) Abnormally-fucosylated haptoglobin: a cancer marker for tumour burden but not gross liver metastasis. Br. J. Cancer 64, 386-390.
21. TURNER G.A. (1995) Haptoglobin a potential reporter molecule for glycosylation changes in disease. Adv. Exp. Med. Biol. 376, 231-238.
22. VERBEKE P., PERICHON M., FRIGUET B. & BAKALA H. (2000) Inhibition of nitric oxide synthase activity by early and advanced glycation end products in cultured rabbit proximal tubular epithelial cells. Biochim. Biophys. Acta. 1502, 481-494.
23. VINCENTI M.P., CLARK I.M. & BRINCKERHOFF C.E. (1994) Using inhibitors of metalloproteinases to treat arthritis. Arthritis Reum. 37, 1115-1126.
24. WESTERMARCK J. & KÀHÄRI V.-M. (1999) Regulation of matrix metalloproteinases expression in tumor invasion. FASEB J. 13, 781-792.
25. WOLF C., ROUYER N., LUTZ Y. ET AL. (1993) Stomelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression. Proc. Nat. Acad. Sci. USA 90, 1843-1847.
26. ZHOU A., APTE S.S., SOININEN R. ET AL. (2000) Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I. Proc. Natl. Acad. Sci. USA 97, 4052-4057.