메뉴 건너뛰기




Volumn 138, Issue 1, 2003, Pages 49-56

Adapalene: Pharmacological and therapeutic features;Adapalene: Profilo farmacologico e terapeutico

Author keywords

Acne vulgaris; Administration and dosage Retinoids; Pharmacology; Therapeutic use Retinoids; Therapy Retinoids

Indexed keywords

ADAPALENE; CLINDAMYCIN PHOSPHATE; DRUG RECEPTOR; ERYTHROMYCIN; RETINOIC ACID;

EID: 0037544215     PISSN: 03920488     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (40)
  • 1
    • 0031845192 scopus 로고    scopus 로고
    • Adapalene for the treatment of acne vulgaris
    • Weiss JS, Shavin JS. Adapalene for the treatment of acne vulgaris. J Am Acad Dermatol 1998;39:S50-4.
    • (1998) J Am Acad Dermatol , vol.39
    • Weiss, J.S.1    Shavin, J.S.2
  • 2
    • 0031817485 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of topical adapalene
    • Shroot B. Pharmacodynamics and pharmacokinetics of topical adapalene. J Am Acad Dermatol 1998;39:S17-24.
    • (1998) J Am Acad Dermatol , vol.39
    • Shroot, B.1
  • 3
    • 0031666357 scopus 로고    scopus 로고
    • Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation
    • Martin B, Meunier C, Montels D, Watts O. Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation. Br J Dermatol 1998;139 Suppl 52:8-11.
    • (1998) Br J Dermatol , vol.139 , Issue.SUPPL. 52 , pp. 8-11
    • Martin, B.1    Meunier, C.2    Montels, D.3    Watts, O.4
  • 6
    • 0030917568 scopus 로고    scopus 로고
    • Skin distribution and pharmaceutical aspects of adapalene gel
    • Allec J, Chatelus A, Wagner N. Skin distribution and pharmaceutical aspects of adapalene gel. J Am Acad Dermatol 1997;36:S119-25.
    • (1997) J Am Acad Dermatol , vol.36
    • Allec, J.1    Chatelus, A.2    Wagner, N.3
  • 7
    • 0025269359 scopus 로고
    • Follicular penetration and distribution of topically applied CD 271, a new naphthoic acid derivative intended for topical acne treatment
    • Jamoulle JC, Grandjean L, Lamaud E, Shroot B, Schaefer BH. Follicular penetration and distribution of topically applied CD 271, a new naphthoic acid derivative intended for topical acne treatment. J Invest Dermatol 1990;94:731-2.
    • (1990) J Invest Dermatol , vol.94 , pp. 731-732
    • Jamoulle, J.C.1    Grandjean, L.2    Lamaud, E.3    Shroot, B.4    Schaefer, B.H.5
  • 8
    • 0031690939 scopus 로고    scopus 로고
    • A new topical retinoid - Why a new topical acne therapy?
    • Cunliffe WJ. A new topical retinoid - why a new topical acne therapy? Br J Dermatol 1998;139 Suppl 52:1-2.
    • (1998) Br J Dermatol , vol.139 , Issue.SUPPL. 52 , pp. 1-2
    • Cunliffe, W.J.1
  • 10
    • 13344259329 scopus 로고    scopus 로고
    • A comparison of the efficacy and safety of adapalene gel 0.1% and tretinoin gel 0.025% in the treatment of acne vulgaris: A multicenter trial
    • Shalita A, Weiss JS, Chalker DK, Ellis CN, Greenspan A, Katz HI et al. A comparison of the efficacy and safety of adapalene gel 0.1% and tretinoin gel 0.025% in the treatment of acne vulgaris: a multicenter trial. J Am Acad Dermatol 1996;34:482-5.
    • (1996) J Am Acad Dermatol , vol.34 , pp. 482-485
    • Shalita, A.1    Weiss, J.S.2    Chalker, D.K.3    Ellis, C.N.4    Greenspan, A.5    Katz, H.I.6
  • 11
    • 0029986751 scopus 로고    scopus 로고
    • Étude comparative de efficacité et de tolérance de gels d'adapalène à 0.1 et 0.03 p. 100 et d'un gel de trétinoïne à 0.025 p.100 dans le traitement de l'acné
    • Alirezai M, Meynadier J, Jablonska S, Czernielewski J, Verschoore M. Étude comparative de efficacité et de tolérance de gels d'adapalène à 0.1 et 0.03 p. 100 et d'un gel de trétinoïne à 0.025 p.100 dans le traitement de l'acné. Ann Dermatol Venereol 1996;123:165-70.
    • (1996) Ann Dermatol Venereol , vol.123 , pp. 165-170
    • Alirezai, M.1    Meynadier, J.2    Jablonska, S.3    Czernielewski, J.4    Verschoore, M.5
  • 12
    • 0030887796 scopus 로고    scopus 로고
    • Adapalene. A review of its pharmacological properties and clinical potential in the management of mild to moderate acne
    • Brogden RN, Goa KL. Adapalene. A review of its pharmacological properties and clinical potential in the management of mild to moderate acne. Drugs 1997;53:511-9.
    • (1997) Drugs , vol.53 , pp. 511-519
    • Brogden, R.N.1    Goa, K.L.2
  • 14
  • 16
    • 0027730315 scopus 로고
    • Adapalene, a new chemical entity with retinoid activity
    • Bernard BA. Adapalene, a new chemical entity with retinoid activity. Skin Pharmacol 1993;6 Suppl 1:61-9.
    • (1993) Skin Pharmacol , vol.6 , Issue.SUPPL. 1 , pp. 61-69
    • Bernard, B.A.1
  • 17
    • 0031005656 scopus 로고    scopus 로고
    • Pharmacology and chemistry of adapalene
    • Shroot B, Michel S. Pharmacology and chemistry of adapalene. J Am Acad Dermatol 1997;36:S96-103.
    • (1997) J Am Acad Dermatol , vol.36
    • Shroot, B.1    Michel, S.2
  • 18
    • 0027166037 scopus 로고
    • Comparison of CD271 (adapalene) and all-trans retinoic acid in human skin: Dissociation of epidermal effects and CRABP-II mRNA expression
    • Griffiths CE, Elder JT, Bernard BA, Rossio P, Cromie MA, Finkel LJ et al. Comparison of CD271 (adapalene) and all-trans retinoic acid in human skin: dissociation of epidermal effects and CRABP-II mRNA expression. J Invest Dermatol 1993;101:325-8.
    • (1993) J Invest Dermatol , vol.101 , pp. 325-328
    • Griffiths, C.E.1    Elder, J.T.2    Bernard, B.A.3    Rossio, P.4    Cromie, M.A.5    Finkel, L.J.6
  • 19
    • 0031693960 scopus 로고    scopus 로고
    • Adapalene 0.1% gel and adapalene 0.1% cream stimulate retinoic acid receptor mediated gene transcription without significant irritative effects in the skin of healthy human volunteers
    • Griffiths CE, Ancian P, Humphries J, Poncet M, Rizova E, Michel S et al. Adapalene 0.1% gel and adapalene 0.1% cream stimulate retinoic acid receptor mediated gene transcription without significant irritative effects in the skin of healthy human volunteers. Br J Dermatol 1998;139 Suppl 52:12-6.
    • (1998) Br J Dermatol , vol.139 , Issue.SUPPL. 52 , pp. 12-16
    • Griffiths, C.E.1    Ancian, P.2    Humphries, J.3    Poncet, M.4    Rizova, E.5    Michel, S.6
  • 20
    • 0025268473 scopus 로고
    • The in vivo and in vitro anti-inflammatory activity of CD271: A new retinoid-like modulator of cell differentiation
    • Hensby C, Cavey D, Bouclier M, Chatelus A, Algate D, Eustache J et al. The in vivo and in vitro anti-inflammatory activity of CD271: a new retinoid-like modulator of cell differentiation. Agents Actions 1990;29:56-8.
    • (1990) Agents Actions , vol.29 , pp. 56-58
    • Hensby, C.1    Cavey, D.2    Bouclier, M.3    Chatelus, A.4    Algate, D.5    Eustache, J.6
  • 21
    • 0025905695 scopus 로고
    • The rhino mouse model: The effects of topically applied all-trans retinoic acid and CD271 on the fine structure of the epidermis and utricle wall of pseudocomedones
    • Bernerd F, Ortonne JP, Bouclier M, Chatelus A, Hensby C. The rhino mouse model: the effects of topically applied all-trans retinoic acid and CD271 on the fine structure of the epidermis and utricle wall of pseudocomedones. Arch Dermatol Res 1991;283:100-7.
    • (1991) Arch Dermatol Res , vol.283 , pp. 100-107
    • Bernerd, F.1    Ortonne, J.P.2    Bouclier, M.3    Chatelus, A.4    Hensby, C.5
  • 22
    • 0025875102 scopus 로고
    • Quantification of epidermal histological changes induced by topical retinoids and CD271 in the rhino mouse model using a standardized image analysis technique
    • Bouclier M, Chatelus A, Ferracin J, Delain C, Shroot B, Hensby CN. Quantification of epidermal histological changes induced by topical retinoids and CD271 in the rhino mouse model using a standardized image analysis technique. Skin Pharmacol 1991;4:65-73.
    • (1991) Skin Pharmacol , vol.4 , pp. 65-73
    • Bouclier, M.1    Chatelus, A.2    Ferracin, J.3    Delain, C.4    Shroot, B.5    Hensby, C.N.6
  • 23
    • 0026513837 scopus 로고
    • Control of epidermal differentiation by a retinoid analogue unable to bind to cytosolic retinoic acid-binding proteins (CRABP)
    • Asselineau D, Cavey MT, Shroot B, Darmon M. Control of epidermal differentiation by a retinoid analogue unable to bind to cytosolic retinoic acid-binding proteins (CRABP). J Invest Dermatol 1992;98: 128-34.
    • (1992) J Invest Dermatol , vol.98 , pp. 128-134
    • Asselineau, D.1    Cavey, M.T.2    Shroot, B.3    Darmon, M.4
  • 26
    • 0033113383 scopus 로고    scopus 로고
    • Effective treatment of localized Darier's disease with adapalene 0.1% gel
    • English JC 3rd, Browne J, Halbach DP. Effective treatment of localized Darier's disease with adapalene 0.1% gel. Cutis 1999;63: 227-30.
    • (1999) Cutis , vol.63 , pp. 227-230
    • English J.C. III1    Browne, J.2    Halbach, D.P.3
  • 27
    • 0031005657 scopus 로고    scopus 로고
    • Skin tolerance of adapalene 0.1% gel in combination with other topical antiacne treatments
    • Caron D, Sorba V, Clucas A, Verschoore M. Skin tolerance of adapalene 0.1% gel in combination with other topical antiacne treatments. J Am Acad Dermatol 1997;36:S113-5.
    • (1997) J Am Acad Dermatol , vol.36
    • Caron, D.1    Sorba, V.2    Clucas, A.3    Verschoore, M.4
  • 28
    • 9844228522 scopus 로고    scopus 로고
    • Efficacy and safety comparison of adapalene (CD271) gel and tretinoin gel in the topical treatment of acne vulgaris: A European multicentre trial
    • Cunliffe WJ, Caputo R, Dreno B, Förstrom L, Heenen M, Orfanos CE et al. Efficacy and safety comparison of adapalene (CD271) gel and tretinoin gel in the topical treatment of acne vulgaris: a European multicentre trial. J Dermatol Treat 1997;8:173-8.
    • (1997) J Dermatol Treat , vol.8 , pp. 173-178
    • Cunliffe, W.J.1    Caputo, R.2    Dreno, B.3    Förstrom, L.4    Heenen, M.5    Orfanos, C.E.6
  • 29
    • 0030988857 scopus 로고    scopus 로고
    • Split-face comparison of adapalene 0.1% gel and tretinoin 0.025% gel in acne patients
    • Caron D, Sorba V, Kerrouche N, Clucas A. Split-face comparison of adapalene 0.1% gel and tretinoin 0.025% gel in acne patients. J Am Acad Dermatol 1997;36:S110-2.
    • (1997) J Am Acad Dermatol , vol.36
    • Caron, D.1    Sorba, V.2    Kerrouche, N.3    Clucas, A.4
  • 30
    • 0030967382 scopus 로고    scopus 로고
    • Clinical efficacy and safety comparison of adapalene gel and tretinoin gel in the treatment of acne vulgaris: Europe and U.S. multicenter trials
    • Cunliffe WJ, Caputo R, Dreno B, Förstrom L, Heenen M, Orfanos CE et al. Clinical efficacy and safety comparison of adapalene gel and tretinoin gel in the treatment of acne vulgaris: Europe and U.S. multicenter trials. J Am Acad Dermatol 1997;36:S126-34.
    • (1997) J Am Acad Dermatol , vol.36
    • Cunliffe, W.J.1    Caputo, R.2    Dreno, B.3    Förstrom, L.4    Heenen, M.5    Orfanos, C.E.6
  • 31
    • 0031716646 scopus 로고    scopus 로고
    • Evaluation of clinical efficacy and safety of adapalene 0.1% gel versus tretinoin 0.025% gel in the treatment of acne vulgaris, with particular reference to the onset of action and impact on quality of life
    • Grosshans E, Marks R, Mascaro JM, Torras H, Meynadier J, Alirezai M et al. Evaluation of clinical efficacy and safety of adapalene 0.1% gel versus tretinoin 0.025% gel in the treatment of acne vulgaris, with particular reference to the onset of action and impact on quality of life. Br J Dermatol 1998;139 Suppl 52:26-33.
    • (1998) Br J Dermatol , vol.139 , Issue.SUPPL. 52 , pp. 26-33
    • Grosshans, E.1    Marks, R.2    Mascaro, J.M.3    Torras, H.4    Meynadier, J.5    Alirezai, M.6
  • 32
    • 0031670256 scopus 로고    scopus 로고
    • A comparison of the efficacy and tolerability of adapalene 0.1% gel versus tretinoin 0.025% gel in patients with acne vulgaris: A meta-analysis of five randomized trials
    • Cunliffe WJ, Poncet M, Loesche C, Versschoore M. A comparison of the efficacy and tolerability of adapalene 0.1% gel versus tretinoin 0.025% gel in patients with acne vulgaris: a meta-analysis of five randomized trials. Br J Dermatol 1998;139 Suppl 52:48-56.
    • (1998) Br J Dermatol , vol.139 , Issue.SUPPL. 52 , pp. 48-56
    • Cunliffe, W.J.1    Poncet, M.2    Loesche, C.3    Versschoore, M.4
  • 33
    • 18744437296 scopus 로고    scopus 로고
    • Split-face clinical and bio-instrumental comparison of 0.1% adapalene and 0.05% tretinoin in facial acne
    • Piérard-Franchimont C, Henry F, Fraiture AL, Fumal I, Piérard GE. Split-face clinical and bio-instrumental comparison of 0.1% adapalene and 0.05% tretinoin in facial acne. Dermatology 1999;198:218-22.
    • (1999) Dermatology , vol.198 , pp. 218-222
    • Piérard-Franchimont, C.1    Henry, F.2    Fraiture, A.L.3    Fumal, I.4    Piérard, G.E.5
  • 34
    • 84898705366 scopus 로고    scopus 로고
    • Etude comparative de la tolérance et de l'efficacité du gel d'adapalène à 0.1% et de la crème de Trétinoine à 0.05% dans l'acné
    • Meynadier J, Cunliffe WJ, Danby W, Dunlap F, Gold MH, Gratton D et al. Etude comparative de la tolérance et de l'efficacité du gel d'adapalène à 0.1% et de la crème de Trétinoine à 0.05% dans l'acné. Ann Dermatol Venereol 2000;127 Suppl 4:S77-227.
    • (2000) Ann Dermatol Venereol , vol.127 , Issue.SUPPL. 4
    • Meynadier, J.1    Cunliffe, W.J.2    Danby, W.3    Dunlap, F.4    Gold, M.H.5    Gratton, D.6
  • 38
    • 0031696537 scopus 로고    scopus 로고
    • Comparative tolerance of adapalene 0.1% gel and six different tretinoin formulations
    • Galvin SA, Gilbert R, Baker M, Guibal F, Tuley MR. Comparative tolerance of adapalene 0.1% gel and six different tretinoin formulations. Br J Dermatol 1998;139 Suppl 52:34-40.
    • (1998) Br J Dermatol , vol.139 , Issue.SUPPL. 52 , pp. 34-40
    • Galvin, S.A.1    Gilbert, R.2    Baker, M.3    Guibal, F.4    Tuley, M.R.5
  • 39
    • 0031686292 scopus 로고    scopus 로고
    • Adapalene 0.1% gel has low skin irritation potential even when applied immediately after washing
    • Dunlap FE, Baker MD, Plott RT, Verschoore M. Adapalene 0.1% gel has low skin irritation potential even when applied immediately after washing. Br J Dermatol 1998;139 Suppl 52:23-5.
    • (1998) Br J Dermatol , vol.139 , Issue.SUPPL. 52 , pp. 23-25
    • Dunlap, F.E.1    Baker, M.D.2    Plott, R.T.3    Verschoore, M.4
  • 40
    • 0031716524 scopus 로고    scopus 로고
    • Adapalene 0.1% gel for the treatment of acne vulgaris: Its superiority compared to tretinoin 0.025% cream in skin tolerance and patient preference
    • Dunlap FE, Mills OH, Tuley MR, Baker MD, Plott RT. Adapalene 0.1% gel for the treatment of acne vulgaris: its superiority compared to tretinoin 0.025% cream in skin tolerance and patient preference. Br J Dermatol 1998;139 Suppl 52:17-22.
    • (1998) Br J Dermatol , vol.139 , Issue.SUPPL. 52 , pp. 17-22
    • Dunlap, F.E.1    Mills, O.H.2    Tuley, M.R.3    Baker, M.D.4    Plott, R.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.