Cloning and characterization of genes encoding trehalose-6-phosphate synthase (TPS1) and trehalose-6-phosphate phosphatase (TPS2) from Zygosaccharomyces rouxii

FEMS Yeast Research

Volumn 3, Issue 4, 2003, Pages 433-440

  Kwon, Hawk Bin ^a   Yeo, Eun Taeg ^b   Hahn, Sang Eun ^b   Bae, Shin Chul ^b   Kim, Dool Yi ^b   Byun, Myung Ok ^b  

^a SunMoon University   (South Korea)

^b National Institute of Animal Science   (South Korea)

Author keywords

Trehalose; Trehalose 6 phosphate phosphatase; Trehalose 6 phosphate synthase; Zygosaccharomyces rouxii

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; FUNGAL DNA; FUNGAL ENZYME; GLUCOSE; TREHALOSE 6 PHOSPHATE PHOSPHATASE; TREHALOSE 6 PHOSPHATE SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DELETION MUTANT; FUNGAL GENE; FUNGAL GENETICS; FUNGUS GROWTH; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE ISOLATION; GENE OVEREXPRESSION; GENETIC COMPLEMENTATION; HEATING; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; TEMPERATURE SENSITIVITY; ZYGOSACCHAROMYCES ROUXII;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE; ZYGOSACCHAROMYCES ROUXII;

EID: 0037540049     PISSN: 15671356     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-1356(03)00035-7     Document Type: Article

References (35)

1. Thevelein, J.M. (1996) Regulation of trehalose metabolism and its relevance to cell growth and function. In: The Mycota (Brambl, R. and Marzluf, G.A., Eds.), pp 395-420. Springer-Verlag, Berlin.
2. Crowe J.H., Carpenter J.F., Crowe L.M., Anchordoguy T.J. Are freezing and dehydration similar stress vectors? A comparison of modes of interaction of stabilizing solutes with biomolecules. Cryobiology. 27:1990;219-231.
3. Iwahashi H., Obuchi K., Fujii S., Komatsu Y. The correlative evidence suggesting that trehalose stabilizes membrane-structure in yeast Saccharomyces cerevisiae. Cell Mol. Biol. 41:1995;763-769.
4. Crowe J.H., Crowe L.M., Chapman D. Preservation of membrane in anhydrobiotic organism: the role of trehalose. Science. 223:1984;701-703.
5. Soto T., Fernandez J., Vicente-Soler J., Cansado J., Gacto M. Accumulation of trehalose by overexpression of tps1, coding for trehalose-6-phosphate synthase, causes increased resistance to multiple stresses in the fission yeast Schizosaccharomyces pombe. Appl. Environ. Microbiol. 65:1999;2020-2024.
6. De Virgilio C., Hottiger T., Dominguez J., Boller T., Wiemken A. The role of trehalose synthesis for the acquisition of thermotolerance in yeast. I. Genetic evidence that trehalose is a thermoprotectant. Eur. J. Biochem. 219:1994;179-186.
7. Nwaka S., Kopp M., Burgert M., Duechler I., Kienle I., Holzer H. Is thermotolerance of yeast dependent on trehalose accumulation? FEBS Lett. 344:1994;225-228.
8. Gadd G.M., Chalmers K., Reed R.H. The role of trehalose in dehydration resistance of Saccharomyces cerevisiae. FEMS Microbiol. Lett. 48:1987;249-254.
9. Hino A., Mihara K., Nakashima K., Takano H. Trehalose levels and survival ratio of freeze-tolerant versus freeze-sensitive yeasts. Appl. Environ. Microbiol. 56:1990;1386-1391.
10. Hazel B.W., Kletsas S., Nevalainen H., Attfield P.V. Involvement of CIF1 (GGS1/TPS1) in osmotic stress response in Saccharomyces cerevisiae. FEBS Lett. 414:1997;353-358.
11. Cabib E., Leloir L.F. The biosynthesis of trehalose phosphate. J. Biol. Chem. 231:1958;259-275.
12. Rimmele M., Boos W. Trehalose-6-phosphate hydrolase of Escherichia coli. J. Bacteriol. 176:1994;5654-5664.
13. Goddijn O.J.M., Smeekens S. Sensing trehalose biosynthesis in plant. Plant J. 14:1998;143-146.
14. Bell W., Klassen P., Ohnacker M., Boller T., Herweijer M., Schoppink P., Van der Zee P., Wiemken A. Characterization of the 56-kDa subunit of yeast trehalose-6-phosphate synthase and cloning of its gene reveal its identity with the product of CIF1, a regulator of carbon catabolite inactivation. Eur. J. Biochem. 209:1992;951-959.
15. De Virgilio C., Burkert N., Bell W., Jeno P., Wiemken A. Disruption of TPS2, the gene encoding the 100-kDa subunit of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae, causes accumulation of trehalose-6-phosphate and loss of trehalose-6-phosphate phosphatase activity. Eur. J. Biochem. 212:1993;315-323.
16. Vuorio O.E., Kalkkinen N., Londesborough J. Cloning of two related genes encoding the 56-kDa and 123-kDa subunit of trehalose synthase from the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 216:1993;846-861.
17. Gonzales M.I., Struck R., Blazquez M.A., Feldmann H., Gancedo C. Molecular cloning of CIF1, a yeast gene necessary for growth on glucose. Yeast. 8:1992;183-192.
18. Thevelein J.M., Hohmann S. Trehalose synthase: guard to the gate of glycolysis in yeast? Trends Biochem. Sci. 20:1995;3-10.
19. Vuorio O.E., Kalkkinen N., Londesborough J. Cloning of two related genes encoding the 56-kDa and 123-kDa subunits of trehalose synthase from the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 216:1993;849-861.
20. Reinders A., Burckert N., Hohmann S., Thevelein J.M., Boller T., Wiemken A., De Virgilio C. Structural analysis of the subunits of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae and their function during heat shock. Mol. Microbiol. 24:1997;687-695.
21. Winderickx J., de Winde J.H., Crauwels M., Hino A., Hohmann S., Van Dijck P., Thevelein J.M. Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control? Mol. Gen. Genet. 252:1996;470-482.
22. Wolschek M.F., Kubicek C.P. The filamentous fungus Aspergillus niger contains two 'differentially regulated' trehalose-6-phosphate synthase-encoding genes, tpsA and tpsB. J. Biol. Chem. 272:1997;2729-2735.
23. Pereira M.D., Eleutherio E.C., Panek A.D. Acquisition of tolerance against oxidative damage in Saccharomyces cerevisiae. BMC Microbiol. 1:2001;11.
24. Soto T., Beltran F.F., Paredes V., Madrid M., Millar J.B., Vicente-Soler J., Cansado J., Gacto M. Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe. Eur. J. Biochem. 269:2002;5056-5065.
25. Parrou J.L., Teste M.A., François J. Effects of various types of stress on the metabolism of reserve carbohydrates in Saccharomyces cerevisiae: genetic evidence for a stress-induced recycling of glycogen and trehalose. Microbiology. 143:1997;1891-1900.
26. Fillinger S., Chaveroche M.K., van Dijck P., de Vries R., Ruijter G., Thevelein J., d'Enfert C. Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans. Microbiology. 147:2001;1851-1862.
27. Kathoda S., Taniguchi K., Sumi H., Nakajima S. Cell wall composition of Zygosaccharomyces rouxii after a shift to a high concentration of NaCl. Agric. Biol. Chem. 55:1991;2757-2763.
28. Kwon H.-B. Molecular cloning and characterization of a gibberellin-responsive gene from the Arabidopsis thaliana ga3 mutant plant. K.J. Genet. 21:1999;171-180.
29. Yeo E.-T., Kwon H.-B., Han S.-E., Lee J.-T., Ryu J.-C., Byun M.-O. Genetic engineering of drought resistant potato plants by introduction of the trehalose-6-phosphate synthase (TPS1) gene from Saccharomyces cerevisiae. Mol. Cell. 10:2000;263-268.
30. Ausubel, F., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A. and Struhl, K. (1999) Short Protocols in Molecular Biology (4th edn.). Wiley, New York.
31. Campbell, I. and Duffus, J.H. (1988) Yeast a Practical Approach. IRL Press.
32. Vogel G., Aeschbacher R.A., Muller J., Boller T., Wiemken A. Trehalose-6-phosphate phosphatase from Arabidopsis thaliana: Identification by functional complementation of the yeast tps2 mutant. Plant J. 13:1998;673-683.
33. Neves M.J., Hohmann S., Bell W., Dumortier F., Luyten K., Ramos J., Cobbaert P., de Koning W., Kaneva Z., Thevelein J.M. Control of glucose influx into glycolysis and pleiotropic effects studied in different isogenic sets of Saccharomyces cerevisiae mutants in trehalose biosynthesis. Curr. Genet. 27:1995;110-122.
34. Elliott B., Haltiwanger R.S., Futcher B. Synergy between trehalose and Hsp 104 for thermotolerance in Saccharomyces cerevisiae. Genetics. 144:1996;923-933.
35. Jorge J.A., Polizeli M.L., Thevelein J.M., Terenzi H.F. Trehalases and trehalose hydrolysis in fungi. FEMS Microbiol. Lett. 154:1997;165-171.