Inactivation of helicase-like transcription factor by promoter hypermethylation in human gastric cancer

Molecular Carcinogenesis

Volumn 37, Issue 2, 2003, Pages 91-97

  Leung, Wai K ^a   Yu, Jun ^a   Bai, Alfa H C ^a   Chan, Michael W Y ^a   Chan, Ka Kui ^a   To, Ka Fai ^a   Chan, Francis K L ^a   Ng, Enders K W ^a   Chung, S C Sydney ^a   Sung, Joseph J Y ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Chromatin remodeling; Gastric cancer; Gene expression; Methylation

Indexed keywords

AZACITIDINE; BISULFITE; HELICASE LIKE TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENE INACTIVATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; STOMACH CARCINOGENESIS; TRANSCRIPTION REGULATION;

ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; CARRIER PROTEINS; CPG ISLANDS; DNA METHYLATION; DNA-BINDING PROTEINS; GASTRIC MUCOSA; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); SEQUENCE ANALYSIS, DNA; STOMACH NEOPLASMS; SULFITES; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0037533708     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.10124     Document Type: Article

References (21)

1. Cairns BR. Emerging roles for chromatin remodeling in cancer biology. Trends Cell Biol 2001;11:S15-S21.
2. Flaus A, Owe-Hughes T. Mechanisms for ATP-dependent chromatin remodeling. Curr Opin Genet Dev 2001;11:148-154.
3. Klochendler-Yeivin A, Muchardt C, Yaniv M. SWI/SNF chromatin remodeling and cancer. Curr Opin Genet Dev 2002;12:73-79.
4. Muschardt C, Yaniv M. When the SWI/SNF complex remodels... the cell cycle. Oncogene 2001;20:3067-3075.
5. Versteege I, Sevenet N, Lange J, et al. Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 1998;394:203-206.
6. Sevenet N, Lellouch-Tubiana A, Schofield D, et al. Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations. Hum Mol Genet 1999;8:2359-2368.
7. Grand F, Kulkarni S, Chase A, Goldman JM, Gordon M, Cross NC. Frequent deletion of hSNF5/INI1, a component of the SWI/SNF complex, in chronic myeloid leukemia. Cancer Res 1999;59:3870-3874.
8. Wong AK, Shanahan F, Chen Y, et al. BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res 2000;60:6171-6177.
9. Moinova HR, Chen WD, Shen L, et al. HLTF gene silencing in human colon cancer. Proc Natl Acad Sci 2002;99:4562-4567.
10. Lauren P. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma an attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 1965;64:31-49.
11. Sobin LH, Wittekind Ch, editors. TNM classification of malignant tumours. 5th edition. New York: Wiley-Liss; 1997. 59 p.
12. Herman JG, Umar A, Polyak K, et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998;95:6870-6875.
13. Kang YH, Lee HS, Kim WH. Promoter methylation and silencing of PTEN in gastric carcinoma. Lab Invest 2002;82:285-291.
14. Byun DS, Lee MG, Chae KS, Ryu BG, Chi SG. Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric carcinoma. Cancer Res 2001;61:7034-7038.
15. Leung WK, Yu J, To KF, et al. Concurrent hypermethylation of multiple tumor related genes in gastric cancer and adjacent normal tissues. Cancer 2001;91:2294-2301.
16. Lee TL, Leung WK, Chan MWY, et al. Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma. Clin Cancer Res 2002;8:1761-1766.
17. Robertson KD, Jones PA. DNA methylation: Past, present, and future directions. Carcinogenesis 2002;21:461-467.
18. Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, Issa JP. CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci USA 1999;96:8681-8686.
19. Sif S, Saurin AJ, Imalzano AN, Kingston RE. Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin-remodeling complex. Curr Opin Genet Dev 2001;15:603-618.
20. Yeivin AK, Muchardt C, Yaniv M. SWI/SNF chromatin remodeling and cancer. Curr Opin Genet Dev 2002;12:73-79.
21. Myohanen SK, Baylin SB, Herman JG. Hypermethylation can selectively silence individual p16ink4A alleles in neoplasia. Cancer Res 1998;58:591-593.