Diketopyridylryanodine has three concentration-dependent effects on the cardiac calcium-release channel/ryanodine receptor

Journal of Biological Chemistry

Volumn 278, Issue 16, 2003, Pages 14237-14248

  Bidasee, Keshore R ^a,d   Xu, Le ^b   Meissner, Gerhard ^b   Besch Jr , Henry R ^c  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOELECTRIC POTENTIALS; CALCIUM; ENZYMES; GROWTH KINETICS; IONIC CONDUCTION;

RYANOIDS;

CELLS;

CALCIUM; DIKETOPYRIDYLRYANODINE; PYRIDYLRYANODINE; RYANODINE; RYANODINE RECEPTOR; UNCLASSIFIED DRUG; C4,C12 DIKETOPYRIDYLRYANODINE; C4,C12-DIKETOPYRIDYLRYANODINE; DRUG DERIVATIVE; LIGAND;

ARTICLE; CALCIUM CONDUCTANCE; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; PRIORITY JOURNAL; ALGORITHM; ANIMAL; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DOG; DOSE RESPONSE; HEART MUSCLE; IC 50; KINETICS; METABOLISM; PROTEIN BINDING; SARCOPLASMIC RETICULUM; TIME;

ALGORITHMS; ANIMALS; BINDING SITES; CALCIUM; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; INHIBITORY CONCENTRATION 50; KINETICS; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; MYOCARDIUM; PROTEIN BINDING; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; TIME FACTORS;

EID: 0037515667     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208372200     Document Type: Article

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