The α-Glucuronidase, GlcA67A, of Cellvibrio japonicus utilizes the carboxylate and methyl groups of aldobiouronic acid as important substrate recognition determinants

Journal of Biological Chemistry

Volumn 278, Issue 22, 2003, Pages 20286-20292

  Nagy, Tibor ^a   Nurizzo, Didier ^b,d   Davies, Gideon J ^b   Biely, Peter ^c   Lakey, Jeremy H ^a   Bolam, David N ^a   Gilbert, Harry J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

^c INSTITUTE OF CHEMISTRY   (Slovakia)

^d EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CARBON; CELLS; CRYSTAL STRUCTURE; HYDROGEN BONDS; HYDROLYSIS; HYDROPHOBICITY; MUTAGENESIS; OLIGOMERS; PLANTS (BOTANY); SUBSTRATES; XYLOSE;

ENZYME-LIGAND COMPLEXES;

ENZYMES;

ALANINE; ALDOBIOURONIC ACID; ALPHA GLUCURONIDASE; ASPARTIC ACID; BETA GLUCURONIDASE; CARBOXYLIC ACID; GLUTAMIC ACID; METHYL GROUP; OLIGOSACCHARIDE; TRYPTOPHAN; UNCLASSIFIED DRUG; URONIC ACID; VALINE; XYLAN; XYLOSE; ALPHA-GLUCURONIDASE; GLYCOSIDASE; PRIMER DNA;

ARTICLE; BETA SHEET; BINDING AFFINITY; CATALYSIS; CELLVIBRIO; CELLVIBRIO JAPONICUS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; HYDROLYSIS; HYDROPHOBICITY; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY;

CELLVIBRIO; CELLVIBRIO JAPONICUS; NEGIBACTERIA;

AMINO ACID SEQUENCE; BASE SEQUENCE; CARBOXYLIC ACIDS; CELLVIBRIO; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOSIDE HYDROLASES; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; URONIC ACIDS;

EID: 0037490140     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302205200     Document Type: Article

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