메뉴 건너뛰기




Volumn 81, Issue 7, 2003, Pages 790-799

Modeling of scale-down effects on the hydrodynamics of expanded bed adsorption columns

Author keywords

Expanded bed adsorption; Mathematical model; Scale down; Scale up; Velocity profile

Indexed keywords

ADSORPTION; CENTRIFUGATION; CONCENTRATION (PROCESS); FILTRATION; HYDRODYNAMICS; PACKED BEDS; VISCOSITY;

EID: 0037473194     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10522     Document Type: Article
Times cited : (9)

References (20)
  • 1
    • 0012255465 scopus 로고    scopus 로고
    • no. 18-1124-1126. Uppsala, Sweden: Amersham
    • Amersham Pharmacia Biotech. 1999. Expanded bed adsorption, no. 18-1124-26. Uppsala, Sweden: Amersham.
    • (1999) Expanded Bed Adsorption
  • 2
    • 0023846472 scopus 로고
    • Charactéristiques hydrodynamiques de la fluidisation liquide-solide: Influence du distributeur
    • Bascoul A, Delmas H, Couderc JP, 1988. Charactéristiques hydrodynamiques de la fluidisation liquide-solide: Influence du distributeur. Chem Eng J 37:11-24.
    • (1988) Chem Eng J , vol.37 , pp. 11-24
    • Bascoul, A.1    Delmas, H.2    Couderc, J.P.3
  • 4
    • 0033402074 scopus 로고    scopus 로고
    • Development and scale up of a capture step (expanded bed chromatography) for a fusion protein expressed intracellularly in Escherichia coli
    • Brobjer M. 1999. Development and scale up of a capture step (expanded bed chromatography) for a fusion protein expressed intracellularly in Escherichia coli. Bioseparation 8:219-228.
    • (1999) Bioseparation , vol.8 , pp. 219-228
    • Brobjer, M.1
  • 5
    • 0033385880 scopus 로고    scopus 로고
    • The effect of column verticality on separation efficiency in expanded bed adsorption
    • Bruce LJ, Ghose S, Chase HA. 1999. The effect of column verticality on separation efficiency in expanded bed adsorption. Bioseparation 8: 69-75.
    • (1999) Bioseparation , vol.8 , pp. 69-75
    • Bruce, L.J.1    Ghose, S.2    Chase, H.A.3
  • 6
    • 0001503526 scopus 로고
    • Batch fluidized ion-exchange column for stream containing suspended particles
    • Buijs A, Wesselingh JA. 1980. Batch fluidized ion-exchange column for stream containing suspended particles. J Chromatogr 201:319-327.
    • (1980) J Chromatogr , vol.201 , pp. 319-327
    • Buijs, A.1    Wesselingh, J.A.2
  • 7
    • 0030569930 scopus 로고    scopus 로고
    • Development of operating conditions for protein purification using expanded bed techniques: The effect of the degree of bed expansion on adsorption performance
    • Chang YK, Chase HA. 1996. Development of operating conditions for protein purification using expanded bed techniques: The effect of the degree of bed expansion on adsorption performance. Biotechnol Bioeng 49:512-526.
    • (1996) Biotechnol Bioeng , vol.49 , pp. 512-526
    • Chang, Y.K.1    Chase, H.A.2
  • 8
    • 0034688320 scopus 로고    scopus 로고
    • Facilited downstream processing of a histidine-tagged protein from unclarified E. coli homogenates using immobilized metal affinity expanded bed adsorption
    • Clemmitt RH, Chase HA. 2000. Facilited downstream processing of a histidine-tagged protein from unclarified E. coli homogenates using immobilized metal affinity expanded bed adsorption. Biotechnol Bioeng 67:206-216.
    • (2000) Biotechnol Bioeng , vol.67 , pp. 206-216
    • Clemmitt, R.H.1    Chase, H.A.2
  • 9
    • 0343288699 scopus 로고    scopus 로고
    • The influence of complex biological feedstock on the fluidization and bed stability in expanded adsorption
    • Fernandez-Lahore HM, Kleef R, Kula MR, Thommes J. 1999. The influence of complex biological feedstock on the fluidization and bed stability in expanded adsorption. Biotechnol Bioeng 64:484-496.
    • (1999) Biotechnol Bioeng , vol.64 , pp. 484-496
    • Fernandez-Lahore, H.M.1    Kleef, R.2    Kula, M.R.3    Thommes, J.4
  • 10
    • 0032900643 scopus 로고    scopus 로고
    • Interaction of mammalian cell culture broth with adsorbents in expanded bed adsorption of monoclonal antibodies
    • Feuser J, Halfar M, Lutkemeyer D, Ameskamp N, Kula MR, Thommes J. 1999. Interaction of mammalian cell culture broth with adsorbents in expanded bed adsorption of monoclonal antibodies. Proc Biochem 34:159-165.
    • (1999) Proc Biochem , vol.34 , pp. 159-165
    • Feuser, J.1    Halfar, M.2    Lutkemeyer, D.3    Ameskamp, N.4    Kula, M.R.5    Thommes, J.6
  • 12
    • 0034072919 scopus 로고    scopus 로고
    • Expanded bed chromatography of proteins in small columns. I. Scale down and validation
    • Ghose S, Chase HA. 2000. Expanded bed chromatography of proteins in small columns. I. Scale down and validation. Bioseparation 9:21-28.
    • (2000) Bioseparation , vol.9 , pp. 21-28
    • Ghose, S.1    Chase, H.A.2
  • 14
    • 0032791201 scopus 로고    scopus 로고
    • Simulation of chromatographic processes applied to separation of proteins
    • Kempe H, Axelsson A, Nilsson B, Zacchi G. 1999. Simulation of chromatographic processes applied to separation of proteins. J Chromatogr A 846:1-12.
    • (1999) J Chromatogr A , vol.846 , pp. 1-12
    • Kempe, H.1    Axelsson, A.2    Nilsson, B.3    Zacchi, G.4
  • 15
    • 0035815513 scopus 로고    scopus 로고
    • Theories of chromatographic efficiency applied to expanded bed
    • Palsson E, Axelsson A, Larsson PO. 2001. Theories of chromatographic efficiency applied to expanded bed. J Chromatogr A 912:235-248.
    • (2001) J Chromatogr A , vol.912 , pp. 235-248
    • Palsson, E.1    Axelsson, A.2    Larsson, P.O.3
  • 16
    • 0032570616 scopus 로고    scopus 로고
    • Purification of a recombinant protein expressed in yeast: Optimization of analytical and preparative chromatography
    • Raymond F, Rolland D, Gauthier M, Jolivet M. 1998. Purification of a recombinant protein expressed in yeast: Optimization of analytical and preparative chromatography. J Chromatogr B 706:113-121.
    • (1998) J Chromatogr B , vol.706 , pp. 113-121
    • Raymond, F.1    Rolland, D.2    Gauthier, M.3    Jolivet, M.4
  • 17
    • 0012255269 scopus 로고    scopus 로고
    • Solution of the convection dispersion-reaction equation by a sequencing method
    • In press
    • Renou S, Perrier M, Dochain D, Gendron S. 2002. Solution of the convection dispersion-reaction equation by a sequencing method. Comp Chem Eng, In press.
    • (2002) Comp Chem Eng
    • Renou, S.1    Perrier, M.2    Dochain, D.3    Gendron, S.4
  • 19
    • 0029394784 scopus 로고
    • Hydrodynamics and performance in fluidized bed adsorption
    • Thommes J, Weilher M, Karau A, Kula MR. 1995. Hydrodynamics and performance in fluidized bed adsorption. Biotechnol Bioeng 48: 367-374.
    • (1995) Biotechnol Bioeng , vol.48 , pp. 367-374
    • Thommes, J.1    Weilher, M.2    Karau, A.3    Kula, M.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.