Oxidative cyclization of amino alcohols catalyzed by a Cp*lr complex. Synthesis of indoles, 1,2,3,4-tetrahydroquinolines, and 2,3,4,5-tetrahydro-1-benzazepine

Organic Letters

Volumn 4, Issue 16, 2002, Pages 2691-2694

  Fujita, Ken Ichi ^a   Yamamoto, Kazunari ^a   Yamaguchi, Ryohei ^a  

^a KYOTO UNIVERSITY   (Japan)

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EID: 0001334479     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol026200s     Document Type: Article

References (24)

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22. 3 (0.10 mmol) were suspended in toluene (2 mL). Then the substrate (1.0 mmol) was added, and the mixture was stirred under reflux for 20 h. The products were isolated by silica gel column chromatography (eluent: hexane-ethyl acetate). The products were identified by NMR analysis.
23. 2 (0.025 mmol) at 120°C for 17 h gave aniline in 17% yield. Unpublished results.
24. 3 (0.10 mmol) in toluene (2 mL). Then the substrate (1.0 mmol) was added and sealed, and the mixture was stirred at 111°C for 20 h. The products were isolated by silica gel column chromatography (eluent: hexanes-ethyl acetate). The products were identified by NMR analysis.