Isolation and characterization of androgen receptor mutant, AR(M749L), with hypersensitivity to 17-β estradiol treatment

Journal of Biological Chemistry

Volumn 278, Issue 9, 2003, Pages 7699-7708

  Thin, Tin Htwe ^b   Wang, Liang ^b   Kim, Eungseok ^b   Collins, Loretta L ^b   Basavappa, Ravi ^b   Chang, Chawnshang ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; MOLECULAR BIOLOGY; PHYSIOLOGY;

LIGANDS;

HORMONES;

AMINO ACID; ANDROGEN RECEPTOR; ANTIANDROGEN; DEXAMETHASONE; ESTRADIOL; PROGESTERONE; LIGAND; STEROID; TRYPSIN;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ESTROGEN BINDING; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR MODEL; MUTANT; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN ISOLATION; RECEPTOR AFFINITY; RECEPTOR SENSITIVITY; REPORTER GENE; SCREENING; SITE DIRECTED MUTAGENESIS; TRANSACTIVATION; XENOGRAFT; ANIMAL; BINDING SITE; CELL CULTURE; CELL STRAIN COS1; CHEMICAL STRUCTURE; DOSE RESPONSE; GENETICS; KINETICS; METABOLISM; MUTATION; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALIA;

ANIMALS; BINDING SITES; COS CELLS; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; GENES, REPORTER; HUMANS; KINETICS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; POLYMERASE CHAIN REACTION; PROGESTERONE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANDROGEN; SIGNAL TRANSDUCTION; STEROIDS; TRANS-ACTIVATION (GENETICS); TRYPSIN; TUMOR CELLS, CULTURED;

EID: 0037470194     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206172200     Document Type: Article

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