Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in Saccharomyces cerevisiae

Journal of Biological Chemistry

Volumn 278, Issue 9, 2003, Pages 7325-7334

  Funato, Kouichi ^a   Lombardi, Ruben ^a   Vallée, Béatrice ^a   Riezman, Howard ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL MEMBRANES; BIOSYNTHESIS; CELLS;

BIOSYNTHETIC POOL;

PHOSPHORUS COMPOUNDS;

CERAMIDE; FUNGAL ENZYME; LONG CHAIN SPHINGOID BASE; LONG CHAIN SPHINGOID BASE 3 PHOSPHATASE; LONG CHAIN SPHINGOID BASE 4 PHOSPHATASE; LONG CHAIN SPHINGOID BASE 5 PHOSPHATASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; LCB3 PROTEIN, S CEREVISIAE; LCB4 PROTEIN, S CEREVISIAE; LCB5 PROTEIN, S CEREVISIAE; PHOSPHATASE; SACCHAROMYCES CEREVISIAE PROTEIN; SPHINGOLIPID;

ARTICLE; CYTOSOL; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; CELL FRACTIONATION; CELL MEMBRANE; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENE DELETION; GOLGI COMPLEX; METABOLISM; PHYSIOLOGY;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SPHINGIODEA;

CELL MEMBRANE; CERAMIDES; CYTOSOL; ENDOPLASMIC RETICULUM; GENE DELETION; GOLGI APPARATUS; MICROSCOPY, FLUORESCENCE; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; SPHINGOLIPIDS; SUBCELLULAR FRACTIONS;

EID: 0037470183     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209925200     Document Type: Article

References (46)

1. Hannun, Y. A., Luberto, C., and Argraves, K. M. (2001) Biochemistry 40, 4893-4903
2. Hannun, Y. A., and Obeid, L. M. (2002) J. Biol. Chem. 277, 25847-25850
3. Spiegel, S., and Milstien, S. (2002) J. Biol. Chem. 277, 25851-25854
4. Spiegel, S., English, D., and Milstien, S. (2002) Trends Cell Biol. 12, 236-242
5. Olivera, A., and Spiegel, S. (2001) Prostaglandins 64, 123-134
6. Kohama, T., Olivera, A., Edsall, L., Nagiec, M. M., Dickson, R., and Spiegel, S. (1998) J. Biol. Chem. 273, 23722-23728
7. Liu, H., Sugiura, M., Nava, V. E., Edsall, L. C., Kono, K., Poulton, S., Milstien, S., Kohama, T., and Spiegel, S. (2000) J. Biol. Chem. 275, 19513-19520
8. Zhou, J., and Saba, J. D. (1998) Biochem, Biophys. Res. Commun. 242, 502-507
9. Van Veldhoven, P. P., Gijsbers, S., Mannaerts, G. P., Vermeesch, J. R., and Brys, V. (2000) Biochim. Biophys. Acta 1487, 128-134
10. Mandala, S. M., Thornton, R., Galve-Roperh, I., Poulton, S., Peterson, C., Olivera, A., Bergstrom, J., Kurtz, M. B., and Spiegel, S. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7859-7864
11. Le Stunff, H., Peterson, C., Thornton, R., Milstien, S., Mandala, S. M., and Spiegel, S. (2002) J. Biol. Chem. 277, 8920-8927
12. Gijsbers, S., Van der Hoeven, G., and Van Veldhoven, P. P. (2001) Biochim. Biophys. Acta 1532, 37-50
13. Nagiec, M. M., Skrzypek, M., Nagiec, E. E., Lester, R. L., and Dickson, R. C. (1998) J. Biol. Chem. 273, 19437-19442
14. Saba, J. D., Nara, F., Bielawska, A., Garrett, S., and Hannun, Y. A. (1997) J. Biol. Chem. 272, 26087-26090
15. Qie, L., Nagiec, M. M., Baltisberger, J. A., Lester, R. L., and Dickson, R. C. (1997) J. Biol. Chem. 272, 16110-16117
16. Mao, C., Wadleigh, M., Jenkins, G. M., Hannun, Y. A., and Obeid, L. M. (1997) J. Biol. Chem. 272, 28690-28694
17. Mandala, S. M., Thornton, R., Tu, Z., Kurtz, M. B., Nickels, J., Broach, J., Menzeleev, R., and Spiegel, S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 150-155
18. Mao, C., Saba, J. D., and Obeid, L. M. (1999) Biochem. J. 342, 667-675
19. Jenkins, G. M., and Hannun, Y. A. (2001) J. Biol. Chem. 276, 8574-8581
20. Kim, S., Fyrst, H., and Saba, J. (2000) Genetics 156, 1519-1529
21. Zhang, X., Skrzypek, M. S., Lester, R. L., and Dickson, R. C. (2001) Curr. Genet. 40, 221-233
22. Ferguson-Yankey, S. R., Skrzypek, M. S., Lester, R. L., and Dickson, R. C. (2002) Yeast 19, 573-586
23. Levine, T. P., Wiggins, C. A., and Munro, S. (2000) Mol. Biol. Cell 11, 2267-2281
24. Zanolari, B., Friant, S., Funato, K., Sutterlin, C., Stevenson, B. J., and Riezman, H. (2000) EMBO J. 19, 2824-2833
25. Salama, N. R., Yeung, T., and Schekman, R. W. (1993) EMBO J. 12, 4073-4082
26. Funato, K., and Riezman, H. (2001) J. Cell Biol. 155, 949-959
27. Nishikawa, S., and Nakano, A. (1991) Biochim. Biophys. Acta 1093, 135-143
28. Schroder, S., Schimmoller, F., Singer-Kruger, B., and Riezman, H. (1995) J. Cell Biol. 131, 895-912
29. Beck, T., Schmidt, A., and Hall, M. N. (1999) J. Cell Biol. 146, 1227-1237
30. Schorling, S., Vallee, B., Barz, W. P., Riezman, H., and Oesterhelt, D. (2001) Mol. Biol. Cell 12, 3417-3427
31. Merrill, A. H., Jr., van Echten, G., Wang, E., and Sandhoff, K. (1993) J. Biol. Chem. 268, 27299-27306
32. Zhong, W., Murphy, D. J., and Georgopapadakou, N. H. (1999) FEBS Lett. 463, 241-244
33. Dillon, D. A., Chen, X., Zeimetz, G. M., Wu, W. I., Waggoner, D. W., Dewald, J., Brindley, D. N., and Carman, G. M. (1997) J. Biol. Chem. 272, 10361-10366
34. Toke, D. A., Bennett, W. L., Dillon, D. A., Wu, W. I., Chen, X., Ostrander, D. B., Oshiro, J., Cremesti, A., Voelker, D. R., Fischl, A. S., and Carman, G. M. (1998) J. Biol. Chem. 273, 3278-3284
35. Toke, D. A., Bennett, W. L., Oshiro, J., Wu, W. I., Voelker, D. R., and Carman, G. M. (1998) J. Biol. Chem. 273, 14331-14338
36. Guillas, I., Kirchman, P. A., Chuard, R., Pfefferli, M., Jiang, J. C., Jazwinski, S. M., and Conzelmann, A. (2001) EMBO J. 20, 2655-2665
37. Benedetti, H., Raths, S., Crausaz, F., and Riezman, H. (1994) Mol. Biol. Cell 5, 1023-1037
38. Manolson, M. F., Proteau, D., Preston, R. A., Stenbit, A., Roberts, B. T., Hoyt, M. A., Preuss, D., Mulholland, J., Botstein, D., and Jones, E. W. (1992) J. Biol. Chem. 267, 14294-14303
39. Barz, W. P., and Walter, P. (1999) Mol. Biol. Cell 10, 1043-1059
40. Hait, N. C., Fujita, K., Lester, R. L., and Dickson, R. C. (2002) FEBS Lett. 532, 97-102
41. Lacana, E., Maceyka, M., Milstien, S., and Spiegel, S. (2002) J. Biol. Chem. 277, 32947-32953
42. Hayashi, S., Okada, T., Igarashi, N., Fujita, T., Jahangeer, S., and Nakamura, S. I. (2002) J. Biol. Chem. 277, 33319-33324
43. Voelker, D. R. (1993) J. Biol. Chem. 268, 7069-7074
44. Vidugiriene, J., Sharma, D. K., Smith, T. K., Baumann, N. A., and Menon, A. K. (1999) J. Biol. Chem. 274, 15203-15212
45. Kohlwein, S. D., Eder, S., Oh, C. S., Martin, C. E., Gable, K., Bacikova, D., and Dunn, T. (2001) Mol. Cell. Biol. 21, 109-125
46. Banno, Y., Kato, M., Hara, A., and Nozawa, Y. (1998) Biochem. J. 335, 301-304