Conformationally-restricted analogues and partition coefficients of the 5-HT3 serotonin receptor ligands meta-Chlorophenylbiguanide (mCPBG) and meta-Chlorophenylguanidine (mCPG)

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 6, 2003, Pages 1119-1123

  Rahman, Ashraf A ^a   Daoud, Maha Khalifa ^a   Dukat, Małgorzata ^a   Herrick Davis, Katharine ^b   Purohit, Anil ^b   Teitler, Milt ^b   Do Amaral, Antonia Taveres ^c   Malvezzi, Alberto ^c   Glennon, Richard A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ALBANY MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4 (3 CHLOROPHENYL)AMINOPYRIMIDINE; 2 AMINO 5 CHLORO 3,4 DIHYDROQUINAZOLINE; 2 AMINO 7 CHLORO 3,4 DIHYDROQUINAZOLINE; BIGUANIDE DERIVATIVE; GUANIDINE DERIVATIVE; SEROTONIN 3 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; LIPID SOLUBILITY; PARTITION COEFFICIENT; PH; RECEPTOR AFFINITY;

EID: 0037463784     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00044-1     Document Type: Article

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