Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics

Brain Research

Volumn 964, Issue 1, 2003, Pages 83-90

  Arai, Shigeaki ^a   Morita, Katsuya ^a   Kitayama, Shigeo ^a   Kumagai, Kei ^a   Kumagai, Michio ^b   Kihira, Kenji ^b   Dohi, Toshihiro ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Cocaine; Inhibition of monoamine transporter; Kindling; Local anesthetic; Seizure

Indexed keywords

1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE; CITALOPRAM; COCAINE; DESIPRAMINE; DOPAMINE UPTAKE INHIBITOR; LIDOCAINE; LOCAL ANESTHETIC AGENT; MAPROTILINE; MEPRYLCAINE; NORADRENALIN TRANSPORTER; NORADRENALIN UPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CONVULSION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG SENSITIZATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

ADRENERGIC UPTAKE INHIBITORS; ANESTHETICS, LOCAL; ANIMALS; BRAIN; BRAIN CHEMISTRY; CITALOPRAM; COCAINE; DESIPRAMINE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; LIDOCAINE; MALE; MAPROTILINE; MICE; MICE, INBRED ICR; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PIPERAZINES; SEIZURES; SEROTONIN UPTAKE INHIBITORS; SYMPORTERS; TIME FACTORS;

EID: 0037458523     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)04068-4     Document Type: Article

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