Inhibition of T cell function during malaria: Implications for immunology and vaccinology

Journal of Experimental Medicine

Volumn 197, Issue 2, 2003, Pages 137-141

  Urban, Britta C ^a   Roberts, David J ^b,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MALARIA VACCINE;

DENDRITIC CELL; IMMUNE RESPONSE; MALARIA; PLASMODIUM; PRIORITY JOURNAL; PROPHYLAXIS; REVIEW; T LYMPHOCYTE; VACCINATION;

ANIMALS; ANTIGENS, PROTOZOAN; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; HUMANS; IMMUNE TOLERANCE; MALARIA VACCINES; MALARIA, FALCIPARUM; MICE; PLASMODIUM FALCIPARUM; T-LYMPHOCYTES;

EID: 0037454945     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20022003     Document Type: Review

References (40)

1. Roberts, D.J., A.G. Craig, A.R. Berendt, R. Pinches, G. Nash, K. Marsh, and C.I. Newbold. 1992. Rapid switching to multiple antigenic and adhesive phenotypes in malaria. Nature. 357:689-692.
2. Bolad, A., and K. Berzins. 2000. Antigenic diversity of Plasmodium falciparum and antibody-mediated parasite neutralization. Scand. J. Immunol. 52:233-239.
3. Urban, B.C., D.J. Ferguson, A. Pain, N. Willcox, M. Plebanski, J.M. Austyn, and D.J. Roberts. 1999. Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells. Nature. 400:73-77.
4. Urban, B.C., N. Willcox, and D.J. Roberts. 2001. A role for CD36 in the regulation of dendritic cell function. Proc. Natl. Acad. Sci. USA. 98:8750-8755.
5. Ocana-Morgner, C., M.M. Mota, and A. Rodriguez. 2002. Malaria blood-stage suppression of liver-stage immunity by dendritic cells. J. Exp. Med. 197:143-151.
6. Banchereau, J., F. Briere, C. Caux, J. Davoust, S. Lebecque, Y.J. Liu, B. Pulendran, and K. Palucka. 2000. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18:767-811.
7. Breman, J.G. 2001. The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. Am. J. Trop. Med. Hyg. 64:1-2. (Suppl):1-11.
8. Newton, C.R., and S. Krishna. 1998. Severe falciparum malaria in children: current understanding of pathophysiology and supportive treatment. Pharmacol. Ther. 79:1-53.
9. Schofield, L., J. Villaquiran, A. Ferreira, H. Schellekens, R. Nussenzweig, and V. Nussenzweig. 1987. Gamma interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites. Nature. 330:664-666.
10. Romero, P., J.L. Maryanski, G. Corradin, R.S. Nussenzweig, V. Nussenzweig, and F. Zavala. 1989. Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria. Nature. 341:323-325.
11. Moreno, A., P. Clavijo, R. Edelman, J. Davis, M. Sztein, D. Herrington, and E. Nardin. 1991. Cytotoxic CD4+ T cells from a sporozoite-immunized volunteer recognize the Plasmodium falciparum CS protein. Int. Immunol. 3:997-1003.
12. Seguin, M.C., F.W. Klotz, I. Schneider, J.P. Weir, M. Goodbary, M. Slayter, J.J. Raney, J.U. Aniagolu, and S.J. Green. 1994. Induction of nitric oxide synthase protects against malaria in mice exposed to irradiated Plasmodium berghei infected mosquitoes: involvement of interferon gamma and CD8+ T cells. J. Exp. Med. 180:353-358.
13. Doolan, D.L., and S.L. Hoffman. 2000. The complexity of protective immunity against liver-stage malaria. J. Immunol. 165:1453-1462.
14. Hill, A.V., C.E. Allsopp, D. Kwiatkowski, N.M. Anstey, P. Twumasi, P.A. Rowe, S. Bennett, D. Brewster, A.J. McMichael, and B.M. Greenwood. 1991. Common west African HLA antigens are associated with protection from severe malaria. Nature. 352:595-600.
15. Lockyer, M.J., K. Marsh, and C.I. Newbold. 1989. Wild isolates of Plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite protein. Mol. Biochem. Parasitol. 37:275-280.
16. Robson, K.J., A. Dolo, I.R. Hackford, O. Doumbo, M.B. Richards, M.M. Keita, T. Sidibe, A. Bosman, D. Modiano, and A. Crisanti. 1998. Natural polymorphism in the thrombospondin-related adhesive protein of Plasmodium falciparum. Am. J. Trop. Med. Hyg. 58:81-98.
17. Escalante, A.A., A.A. Lal, and F.J. Ayala. 1998. Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum. Genetics. 149:189-202.
18. Druilhe, P., and J.L. Perignon. 1994. Mechanisms of defense against P. falciparum asexual blood stages in humans. Immunol. Lett. 41:115-120.
19. Good, M.F., and D.L. Doolan. 1999. Immune effector mechanisms in malaria. Curr. Opin. Immunol. 11:412-419.
20. Bull, P.C., B.S. Lowe, M. Kortok, C.S. Molyneux, C.I. Newbold, and K. Marsh. 1998. Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria. Nat. Med. 4:358-360.
21. Bull, P.C., and K. Marsh. 2002. The role of antibodies to Plasmodium falciparum-infected-erythrocyte surface antigens in naturally acquired immunity to malaria. Trends Microbiol. 10:55-58.
22. Good, M.F. 2001. Towards a blood-stage vaccine for malaria: are we following all the leads? Nat. Rev. Immunol. 1:117-125.
23. Schofield, L., M.C. Hewitt, K. Evans, M.A. Siomos, and P.H. Seeberger. 2002. Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature. 418:785-789.
24. Nussenzweig, R.S., J.P. Vanderberg, H. Most, and C. Orton. 1969. Specificity of protective immunity produced by x-irradiated Plasmodium berghei sporozoites. Nature. 222:488-489.
25. Clyde, D.F. 1975. Immunization of man against falciparum and vivax malaria by use of attenuated sporozoites. Am. J. Trop. Med. Hyg. 24:397-401.
26. Nardin, E., F. Zavala, V. Nussenzweig, and R.S. Nussenzweig. 1999. Pre-erythrocytic malaria vaccine: mechanisms of protective immunity and human vaccine trials. Parassitologia. 41:397-402.
27. Moorthy, V., and A.V. Hill. 2002. Malaria vaccines. Br. Med. Bull. 62:59-72.
28. Seixas, E., C. Cross, S. Quin, and J. Langhorne. 2001. Direct activation of dendritic cells by the malaria parasite, Plasmodium chabaudi chabaudi. Eur. J. Immunol. 31:2970-2978.
29. Luyendyk, J., O.K. Olivas, L.A. Ginger, and A.C. Avery. 2002. Antigen-presenting cell function during Plasmodium yoelii infection. Infect. Immun. 70:2941-2949.
30. Urban, B.C., and D.J. Roberts. 2002. Malaria, monocytes, macrophages and myeloid dendritic cells: sticking of infected erythrocytes switches off host cells. Curr. Opin. Immunol. 14:458-465.
31. Lalvani, A., N. Hurt, M. Aidoo, P. Kibatala, M. Tanner, and A.V. Hill. 1996. Cytotoxic T lymphocytes to Plasmodium falciparum epitopes in an area of intense and perennial transmission in Tanzania. Eur. J. Immunol. 26:773-779.
32. Gilbert, S.C., M. Plebanski, S. Gupta, J. Morris, M. Cox, M. Aidoo, D. Kwiatkowski, B.M. Greenwood, H.C. Whittle, and A.V. Hill. 1998. Association of malaria parasite population structure, HLA, and immunological antagonism. Science. 279:1173-1177.
33. Burkitt, D. 1958. A sarcoma of the jaw in African children. Br. J. Surg. 46:218-223.
34. Whittle, H.C., J. Brown, K. Marsh, B.M. Greenwood, P. Seidelin, H. Tighe, and L. Wedderburn. 1984. T-cell control of Epstein-Barr virus-infected B cells is lost during P. falciparum malaria. Nature. 312:449-450.
35. Greenwood, B.M. 1974. Possible role of a B-cell mitogen in hypergammaglobulinaemia in malaria and trypanosomiasis. Lancet. 1:435-436.
36. Hoffman, I.F., C.S. Jere, T.E. Taylor, P. Munthali, J.R. Dyer, J.J. Wirima, S.J. Rogerson, N. Kumwenda, J.J. Eron, S.A. Fiscus, et al. 1999. The effect of Plasmodium falciparum malaria on HIV-1 RNA blood plasma concentration. AIDS. 13:487-494.
37. Chandramohan, D., and B.M. Greenwood. 1998. Is there an interaction between human immunodeficiency virus and Plasmodium falciparum? Int. J. Epidemiol. 27:296-301.
38. Craig, A., and A. Scherf. 2001. Molecules on the surface of the Plasmodium falciparum infected erythrocyte and their role in malaria pathogenesis and immune evasion. Mol. Biochem. Parasitol. 115:129-143.
39. Kyes, S., P. Horrocks, and C. Newbold. 2001. Antigenic variation at the infected red cell surface in malaria. Annu. Rev. Microbiol. 53:673-767.
40. McGilvray, I.D., L. Serghides, A. Kapus, O.D. Rotstein, and K.C. Kain. 2000. Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparum-parasitized erythrocytes: a role for CD36 in malarial clearance. Blood. 96:3231-3240.