NMR solution structure of the glucagon antagonist [desHis1, desPhe6, Glu9]glucagon amide in the presence of perdeuterated dodecylphosphocholine micelles

Biochemistry

Volumn 42, Issue 10, 2003, Pages 2825-2835

  Ying, Jinfa ^a   Ahn, Jung Mo ^a   Jacobsen, Neil E ^a   Brown, Michael F ^a   Hruby, Victor J ^a,b  

^a University of Arizona   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER SIMULATION; HYDROPHILICITY; HYDROPHOBICITY; MICELLES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH EFFECTS;

STRUCTURAL INFORMATION;

GLUCOSE;

DEUTERIUM; DODECYLPHOSPHORYLCHOLINE; GLUCAGON[1 DEHISTIDINE 6 DEPHENYLALANINE 9 GLUTAMIC ACID] AMIDE; HORMONE ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; DIABETES MELLITUS; DRUG ACTIVITY; DRUG STRUCTURE; GLUCOSE HOMEOSTASIS; HYDROPHOBICITY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM; GLUCAGON; MICELLES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHORYLCHOLINE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037452971     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026629r     Document Type: Article

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