High-resolution solution structure of the EGF-like domain of heregulin-α

Biochemistry

Volumn 35, Issue 11, 1996, Pages 3402-3417

  Jacobsen, Neil E ^a,b   Abadi, Nasrin ^a   Sliwkowski, Mark X ^a   Reilly, Dorothea ^a   Skelton, Nicholas J ^a   Fairbrother, Wayne J ^a  

^a GENENTECH INC   (United States)

^b University of Arizona ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; NEU DIFFERENTIATION FACTOR;

AMINO ACID SEQUENCE; ARTICLE; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; DISULFIDES; GLYCOPROTEINS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEUREGULINS; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SOLUTIONS;

EID: 0029881449     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952626l     Document Type: Article

References (107)

1. Alamandi, M., Romano, A., Curia, M. C., Muraro, R., Fedi, P., Aaronson, S. A., Di Fiore, P. P., & Kraus, M. H. (1995) Oncogene 10, 1813-1821.
2. Altiok, N., Bessereau, J.-L., & Changeux, J.-L. (1995) EMBO J. 14, 4258-4266.
3. Archer. S. J., Ikura, M., Torchia. D. A,. & Bax, A. (1991) J. Magn. Reson. 95, 636-641.
4. Barbacci, E. G., Guarino, B. C., Stroh, J. C., Singleton, D. H., Rosnack, K. J., Moyer. J. D., & Andrews. G. C. (1995) J. Biol. Chem. 270, 9585-9589.
5. Baselga, J., & Mendelsohn, J. (1994) Pharmacol Ther. 64, 127-154.
6. Bax. A., & Davis, D. G. (1985) J. Magn. Reson. 65, 355-360.
7. Bodenhausen, G., Kogler, H., & Ernst, R. R. (1984) J. Magn. Reson. 58, 370-388.
8. Braunschweiler, L., & Ernst, R. R. (1983) J. Magn. Reson. 53, 521 - 528.
9. Braunschweiler, L., Bodenhausen. G., & Ernst, R. R. (1984) Mol. Phys. 48, 535-560.
10. Brünger, A. T., Clore, G. M., Gronenborn, A. M., & Karplus, M. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 3801-3805.
11. Carraway, K. L., III, & Cantley, L. C. (1994) Cell 78, 5-8.
12. Cavanagh, J., & Ranee, M. (1992) J. Magn. Reson. 96, 670-678.
13. Chazin, W. J., & Wright, P. E. (1988) J. Mol. Biol. 202, 623-636.
14. Chu ,G. C., Moscoso, L. M., Sliwkowski, M. X., & Merlie, J. P. (1995) Neuron 14, 329-339.
15. Clore, G. M., Brünger, A. T., Karplus, M., & Gronenborn, A. M. (1986) J. Mol. Biol. 191, 523-551.
16. Clore, G. M., Bax, A., & Gronenborn, A. M. (1991) J. Biomol. NMR 1, 13-22.
17. Clore, G. M., Robien, M. A., & Gronenborn, A. M. (1993) J. Mol. Biol. 231, 82-102.
18. Clubb, R. T., Ferguson. S. B., Walsh, C. T., & Wagner, G. (1994) Biochemistry 33, 2761-2772.
19. Davis, D. G. (1989) J. Magn. Reson. 81, 603-607.
20. Driscoll, P. C., Clore, G. M., Marion, D., Wingfield. P. T., & Gronenborn, A. M. (1990) Biochemistry 29, 3542-3556.
21. Earp, H. S., Dawson, T. L., Li, X., & Yu, H. (1995) Breast Cancer Res. Treat. 35, 115-132.
22. Englander, J. J., Calboun, D. B., & Englander, S. W. (1979) Anal. Biochem. 92, 517-524.
23. Engler, D. A., Montelione, G. T., & Niyogi, S. K. (1990) FEBS Lett. 271, 47-50.
24. Falls. D. L., Rosen, K. M., Corfas, G., Lane, W. S., & Fischbach. G. D. (1993) Cell 72, 801-815.
25. Ferrin, T. E., Huang, C. C., Jarvis. L. E., & Langridge. R. (1988) J. Mol. Graphics 6, 13-27.
26. Fesik, S. W., & Zuiderweg, E. R. P. (1990) Q. Rev. Biophys. 23. 97-131.
27. Gomis-Rüth, F. X., Kress, L. F., Kellermann, J., Mayr, I., Lee, X., Huber. R., & Bode, W. (1994) J. Mol. Biol. 239, 513-544.
28. Graus-Porta, D., Beerli, R. R., & Hynes, N. E. (1995) Mol. Cell Biol. 15, 1182-1191.
29. Groenen, L. C., Nice, E. C., & Burgess, A. W. (1994) Growth Factors 11, 235-257.
30. Guy, P. M., Platko, J. V., Cantley, L. C., Cerione, R. A., & Carraway, K. L., III (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 8132-8136.
31. Harvey, T. S., Wilkinson, A. J., Tappin, M. J., Cooke, R. M., & Campbell, I D. (1991) Eur. J. Biochem. 198, 555-562.
32. Havel, T. F. (1991) Prog. Biophys. Mol. Biol. 56, 43-78.
33. Ho, W.-H., Armanini, M. P., Nuijens, A., Phillips, H. S., & Osheroff, P. L. (1995) J. Biol. Chem. 270, 14523-14532.
34. Holmes, W. E., Sliwkowski, M. X., Akita, R. W., HenzeL W. J , Lee, J., Park, J. W., Yansura, D., Abadi, N., Raab, H., Lewis, G. D., Shepard, H. M., Kuang, W.-J., Wood, W. I., Goeddel, D V., & Vandlen, R. L. (1992) Science 256, 1205-1210.
35. Hommel, U., Dudgeon, T. J., Fallen, A., Edwards, R. M., & Campbell, I. D. (1991) Biochemistry 30, 8891-8898.
36. Hommel, U., Harvey, T. S., Driscoll, P. C., & Campbell, I. D. (1992) J. Mol. Biol. 227, 271-282.
37. Hyberts, S., Goldberg, M. S., Havel, T. F., & Wagner, G. (1992) Protein Sci. 1, 736-751.
38. Hynes, N E. (1993) Semin. Cancer Biol. 4, 19-26.
39. Hynes, N. E., & Stern, D. F. (1994) Biochim. Biophys. Acta 1198, 165-184.
40. Kabsch, W., & Sander, C. (1983) Biopolymers 22, 2577-2637.
41. Katz, B. A., & Kossiakoff, A. (1986) J. Biol. Chem. 261, 15480-15485.
42. Kessler, H., Gemmecker, G., & Steuernagel, S. (1988) Angew. Chem., Int. Ed. Engl. 27, 564-566.
43. Kim, H. H., Sierke, S. L., & Koland, J. G. (1994) J. Biol. Chem. 269, 24747-24755.
44. Kline, A. D., Braun, W., & Wüthrich, K. (1989) J. Mol. Biol. 104, 675-724.
45. Kline, T. P., Brown, F. K., Brown, S. C., Jeffs, P. W., Kopple, K. D., & Mueller, L. (1990) Biochemistry 29, 7805-7813.
46. Kohda, D., & Inagaki, F. (1992a) Biochemistry 31, 677-685.
47. Kohda ,D., & Inagaki, F. (1992b) Biochemistry 31, 11928-11939.
48. Koning, T. M. G., Boelens. R., & Kaptein, R. (1990) J. Magn. Reson. 90, 111-123.
49. Kraulis, P. (1991) J. Appl. Crystallogr. 24, 946-950.
50. Kumar, A., Ernst, R. R., & Wüthrich, K. (1980) Biochem. Biophys. Res. Commun. 95, 1-6.
51. Laskowski, R. A., MacArthur, M. W., Moss. D. S., & Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291.
52. Lee. J., & Wood, W. I. (1993) Genomics 16, 790-791.
53. Lemoine, N. R., Barnes. D. M., Hollywood. D. P., Hughes, C. M., Smith, P., Dublin, E., Prigent, S. A., Gullick, W. J., & Hurst, H. C. (1992a) Br. J. Cancer 66, 1116-1121.
54. Lemoine, N. R., Lobresco. M., Leung, H., Barton, C., Hughes, C. M., Prigent, S. A., Gullick. W. J., & Kloppel, G. (1992b) J. Pathol. 168, 269-273.
55. Levi, A. D., Bunge, R. P., Lofgren, J. A., Meima, L., Hefti, F., Nikolics, K., & Sliwkowski, M. X. (1995) J. Neurosci. 15, 1329-1340.
56. Lewis, G. D., Lofgren, J. A., McMurtrey, A. E., Nuijens, A., Fendly, B. M., Bauer, K. D., & Sliwkowski, M. X. (1995) Cancer Res. (submitted for publication).
57. Live, D. H., Davis, D. G., Agosta, W. C., & Cowburn, D. (1984) J. Am. Chem. Soc. 106, 1939-1941.
58. Ludvigsen, S., & Poulsen, F. M. (1992) J. Biomol. NMR 2. 227-233.
59. Marchionni, M. A., Goodearl, A. D. J., Chen, M. S., Bermmgham-McDonogh, O., Kirk, C., Hendricks, M., Danehy, F., Misumi, D., Sudhalter, J., Kobayashi, K., Wroblewski, D., Lynch, C., Baldassare, M., Hues, L, Davis, J. B., Hsuan, J. J., Totty, N. F., Otsu. M., McBurney, R. N., Waterfield, M. D., Stroobant, P.,. & Gwynnw, D. (1993) Nature 362, 312-318.
60. Marion, D., Driscoll, P. C., Kay. L. E., Wingfield, P. T., Bax. A., Gronenborn, A. M., & Clore, G. M. (1989a) Biochemistry 28, 6150-6156.
61. Marion, D., & Wüthrich, K. (1983) Biochem. Biophys. Res. Commun. 113, 967-974.
62. Marion, D., Ikura, M., & Bax, A. (1989b) J. Magn. Reson. 84, 425-430.
63. Manon, D., Ikura; M., Tschudin, R., & Bax, A. (1989c) J. Magn. Reson. 85, 393-399.
64. Marion, D., Kay, L. E., Sparks, S. W., Torchia, D. A., & Bax, A. (1989d) J. Am. Chem. Soc. 111, 1515-1517.
65. Messerle, B. A., Wider, G., Otting, G., Weber, C., & Wüthrich, K. (1989) J. Magn. Reson. 85, 608-613.
66. Meyer, D., & Birchmeier, C. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 1064-1068.
67. Modjtahedi, H., & Dean, C. (1994) Int. J. Oncol. 4, 277-296.
68. Molday, R. S., Englander, S. W., & Kallen, R. G. (1972) Biochemistry 11, 150-158.
69. Montelione, G. T., Winkler, M. E., Rauenbuehler, P., & Wagner, G. (1989) J. Magn. Reson. 82, 198-204.
70. Montelione, G. T., Wüthrich, K., Burgess, A. W., Nice, E. C., Wagner, G., Gibson, K. D., & Scheraga, H. A. (1992) Biochemistry 31, 236-249.
71. Moscoso, L. M., Chu, G. C., Gautam, M., Noakes, P. G., Merlie, J. P., & Sanes, J. R. (1995) Dev. Biol. 172, 158-169.
72. Moy, F. J., Li. Y.-C., Rauenbuehler, P., Winkler, M. E., Scheraga, H. A., & Montelione, G. T. (1993) Biochemistry 32, 7334-7353.
73. Mudge, A. W. (1993) Curr. Biol. 3, 361-364.
74. Nagata, K., Kohda. D., Hatanaka, H., Ichikawa, S., Matsuda, S., Yamamoto, T., Suzuki, A., & Inagaki, F. (1994) EMBO J. 13, 3517-3523.
75. Nilges, M., Clore. G. M., & Gronenborn, A. M. (1988) FEBS Lett. 239, 317-324.
76. Orr-Urtreger, A., Trakhtenbrot, L., Ben-Levy, R., Wen, D., Rechavi, G., Lonai. P., & Yarden, Y. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 1867-1871.
77. Peles, E., Bacus, S. S., Koski, R. A., Lu, H. S., Wen, D., Ogden, S. G., Ben-Levy, R., & Yarden, Y. (1992) Cell 69, 205-216.
78. Plateau, P., & Guéron, M. (1982) J. Am. Chem. Soc. 104. 7310-7311.
79. Plowman, G. D., Culouscou, J.-M., Whitney, G. S., Green, J. M., Carlton, G. W., Foy, L., Neubauer, M. G., & Shoyab, M. (1993a) Proc. Natl. Acad. Sci. U.S.A. 90, 1746-1750.
80. Plowman. G. D., Green, J. M., Culouscou, J.-M., Carlton, G. W., Rothwell, V. M., & Buckley, S. (1993b) Nature 366, 473-475.
81. Press, W. H., Flannery, B. P., Teukolsky, S. A., & Vetterling, W. T. (1986) Numerical Recipes. The Art of Scientific Computing, Cambridge University Press, Cambridge.
82. Ranee, M. (1987) J. Magn. Reson. 74, 557-564.
83. Ranee, M., & Byrd, R. A. (1983) J. Magn. Reson. 54, 221-240.
84. Ranee, M., & Wright, P. E. (1986) J. Magn. Reson. 66, 372-378.
85. Ranee, M., Sørensen, O. W., Bodenhausen, G., Wagner, G., Ernst, R. R., & Wüthrich, K. (1983) Biochem. Biophvs. Res. Commun. 117, 479-485.
86. Reilly. D., & Fairbrother, W. J. (1994) J. Biomol. NMR 4, 459-462.
87. Robertson, A. D., & Baldwin, R. L. (1991) Biochemistry 30, 9907-9914.
88. Shaka, A. J., Barker, P. B., & Freeman, R. (1985) J. Magn. Reson. 64, 547-552.
89. Sliwkowski, M. X., Schaefer, G., Akita, R. W., Lofgren, J. A., Fitzpatrick, V. D., Nuijens, A., Fendly, B. M., Cerione, R. A., Vandeln, R. L., & Carraway, K. L., III (1994) J. Biol. Chem. 269, 14661-14665.
90. Srinivasan, N., Sowdhamini, R., Ramakrishnan. C., & Balaram, P. (1990) Int. J. Pept. Protein Res. 36, 147-155.
91. Tropp, J. (1980) J. Chem. Phys. 72, 6035-6043.
92. Tzahar, E., Levkowitz, G., Karunagaran, D., Yi, L., Peles, E., Lavi, S., Chang, D., Liu, N., Yayon, A., Wen, D., & Yarden, Y. (1994) J. Biol. Chem. 269, 25226-25233.
93. Vuister, G. W., & Bax, A. (1993) J. Am. Chem. Soc. 115, 7772-7777.
94. Vuister, G. W., Boelens, R., & Kaptein, R. (1988) J. Magn. Reson. 80, 176-185.
95. Vuister, G. W., de Waard, P., Boelens, R., Vliegenthart, J. F. G., & Kaptein, R. (1989) J. Am. Chem. Soc. 111, 772-774.
96. Vuister, G. W., Boelens, R., Padilla, P., Kleywegt, G. J . & Kaptein, R. (1990) Biochemistry 29, 1829-1839.
97. Wagner, G., Braun, W., Havel, T. F., Schaumann, T., Go, N., & Wüthrich, K. (1987) J. Mol. Biol. 196, 611-639.
98. Wallasch, C., Weiss, F. U., Niederfellner, G., Jallal, B., Issing, W., & Ullrich, A. (1995) EMBO J. 14, 4267-4275.
99. Weiner, S. J., Kollman, P. A., Case, D. A., Singh. U. C., Ghio, C., Alagona, G. S., Profeta, J., & Weiner, P. (1984) J. Am. Chem. Soc. 106, 765-784.
100. Weiner, S. J., Kollman, P. A., Nguyen, D. T., & Case. D. A. (1986) J. Comput. Chem. 7, 230-252.
101. Wilmot, C. M., & Thornton, J. M. (1988) J. Mol. Biol. 203, 221-232.
102. Wishart, D. S., Sykes, B. D., & Richards, F. M. (1992) Biochemistry 31, 1647-1651.
103. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids. John Wiley & Sons. Inc., New York.
104. Wüthrich, K., Billeter, M., & Braun, W. (1983) J. Mol. Biol. 169, 949-961.
105. Yip, P. (1990) J. Magn. Reson. 90, 382-383.
106. Zhao, D., & Jardetzky, O. (1994) J. Mol. Biol. 239, 601-607
107. Zuiderweg, E. R. P., Boelens, R., & Kaptein, R. (1985) Biopolvmers 24, 601-610.