X-ray structure of human β3β3 alcohol dehydrogenase. The contribution of ionic interactions to coenzyme binding

Journal of Biological Chemistry

Volumn 271, Issue 29, 1996, Pages 17057-17061

  Davis, Gerard J ^a   Bosron, William F ^a   Stone, Carol L ^a   Owusu Dekyi, Kwabena ^a   Hurley, Thomas D ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b Medical Sciences Building ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DEHYDROGENASE; ARGININE; CYSTEINE; ION; ISOENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRAZOLE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ALCOHOL OXIDATION; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; COENZYME; DISSOCIATION CONSTANT; ENZYME BINDING; ENZYME KINETICS; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

ALCOHOL DEHYDROGENASE; AMINO ACID SEQUENCE; ARGININE; BASE SEQUENCE; BINDING SITES; CALORIMETRY; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DNA, COMPLEMENTARY; HUMANS; ISOENZYMES; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NAD; OLIGODEOXYRIBONUCLEOTIDES; POINT MUTATION; POLYMORPHISM, GENETIC; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; THERMODYNAMICS; VARIATION (GENETICS);

EID: 0030035667     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.29.17057     Document Type: Article

References (32)

1. Crabb, D. W., Bosron, W. F., and Li, T.-K. (1983) Arch. Biochem. Biophys. 224, 299-309
2. Plapp, B. V., Leidal, K. G., Smith, R. K., and Murch, B. P. (1984) Arch. Biochem. Biophys. 230, 30-38
3. Jörnvall, H. (1994) Exp. Suppl. (Basel) 71, 221-229
4. Edenberg, H. J., and Bosron, W. F. (1996) in Comprehensive Toxicology (Geungerich, F. P., ed) Vol. 3, Pergamon Press, New York, in press
5. Bosron, W. F., and Li, T.-K. (1986) Hepatology 6, 502-510
6. Lumeng, L., and Crabb, D. W. (1994) Gastroenterohgy 107, 572-478
7. Jörnvall, H., Hempel, J., Vallee, B. L., Bosron, W. F., and Li, T.-K. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 3024-3028
8. Burnell, J. C., Carr, L. G., Dwulet, F. E., Edenberg, H. J., Li, T.-K., and Bosron, W. F. (1987) Biochem. Biophys. Res. Commun. 146, 1227-1233
9. Bosron, W. F., Magnes, L. J., and Li, T.-K. (1993) Biochem. Genet. 21, 735-744
10. Bosron, W. F., and Li, T.-K. (1988) in Biomedical and Social Aspects of Alcohol and Alcoholism (Kuriyama, K., Takada, A., and Ishii, H., eds) pp. 31-34, Elsevier Science Publishers B.V., Amsterdam
11. Burnell, J. C., Li, T.-K., and Bosron, W. F. (1989) Biochemistry 28, 6810-6815
12. Eklund, H., Nordström, B., Zeppezauer, E., Söderlund, G., Ohlsson, I., Boiwe, T., Söderberg, B.-O., Tapia, O., Bränden, C.-I., and Åkeson, Å. (1976) J. Mol. Biol. 102, 27-59
13. Eklund, H., Samama, J.-P., and Wallén, L. (1982) Biochemistry 21, 4858-4866
14. Hurley, T. D., Bosron, W. F., Stone, C. L., and Amzel, L. M. (1994) J. Mol. Biol. 239, 415-429
15. Edenberg, H. J., Dailey, T. L., and Zhang, K. (1989) in Enzymology and Molecular Biology of Carbonyl Metabolism (Weiner, H., and Flynn, T. G., eds) Vol. 2, pp. 181-192, Alan R. Liss Inc., New York
16. Hurley, T. D., Edenberg, H. J., and Bosron, W. F. (1990) J. Biol. Chem. 265, 16366-16372
17. Stone, C. L., Bosron, W. F., and Dunn, M. F. (1993) J. Biol. Chem. 268, 892-899
18. Kusnadi, A. R. (1989) Effect of Amino Acid Substitutions in Human Liver Alcohol Dehydrogenase on Inactivation by lodoacetate pp. 51-52, M.Sc. thesis, Indiana University School of Medicine, Indianapolis
19. Laemmli, U. K. (1970) Nature 227, 680-685
20. Wray, W., Boulikas, T., Wray, V. P., and Hancock, R. (1981)Anal. Biochem. 11, 97-203
21. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
22. Brünger, A. (1988) J. Mol. Biol. 203, 803-816
23. Sack, J. S. (1988) J. Mol. Graph. 6, 224-226
24. Cleland, W. W. (1979) Methods Enzymol. 63, 103-138
25. Connolly, M. L. (1983) J. Appl. Cryst. 16, 548-558
26. Hurley, T. D., Bosron, W. F., Hamilton, J. A., and Amzel, L. M. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 8149-8153
27. Luzatti, P. V. (1952) Acta Crystallogr. 5, 802-810
28. Warshel, A., and Åqvist, J. (1991) Annu. Rev. Biophys. Biophys. Chem. 20, 267-298
29. Stone, C. L., Hurley, T. D., Amzel, L. M., Dunn, M. F., and Bosron, W. F. (1993) in Enzymology and Molecular Biology of Carbonyl Metabolism (Weiner, H., ed) Vol. 4, pp. 429-437, Plenum Publishing Corp., New York
30. Burnell, J. C., and Bosron, W. (1989) in Human Metabolism (Crow, K. E., and Batt, R. D., eds) Vol. 2, pp. 65-75, CRC Press, Inc., Boca Baton, FL
31. Davis, G. J., Carr, L. G., Hurley, T. D., Li, T.-K, and Bosron, W. F. (1994) Arch. Biochem. Biophys. 311, 307-312
32. Hurley, T. D., and Bosron, W. F. (1992) Biochem. Biophys. Res. Commun. 183, 93-99