메뉴 건너뛰기




Volumn 72, Issue 9, 2003, Pages 1039-1048

Cardiac electrophysiological modulation by NS-7, a novel neuroprotective drug, of guinea pig ventricular muscles

Author keywords

293B; Action potential; Ca dependent; E 4031; Frequency dependent; Guinea pig ventricular cells; Neuroprotective drug; NS 7

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; 4 (4 FLUOROPHENYL) 2 METHYL 6 (5 PIPERIDINOPENTYLOXY)PYRIMIDINE; CALCIUM ION; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION;

EID: 0037449369     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)02359-7     Document Type: Article
Times cited : (3)

References (28)
  • 1
    • 0030929915 scopus 로고    scopus 로고
    • Inhibition of ischemia-induced fodrin breakdown by a novel phenylpyrimidine derivative NS-7: An implication for its neuroprotective action in rats with middle cerebral artery occlusion
    • Takagaki Y., Itoh Y., Aoki Y., Ukai Y., Yoshikuni Y., Kimura K. Inhibition of ischemia-induced fodrin breakdown by a novel phenylpyrimidine derivative NS-7: an implication for its neuroprotective action in rats with middle cerebral artery occlusion. J. Neurochem. 68:1997;2507-2513.
    • (1997) J. Neurochem. , vol.68 , pp. 2507-2513
    • Takagaki, Y.1    Itoh, Y.2    Aoki, Y.3    Ukai, Y.4    Yoshikuni, Y.5    Kimura, K.6
  • 2
    • 0035142935 scopus 로고    scopus 로고
    • Cerebroprotective effects of NS-7, a novel pyrimidine derivative, in rats after permanent middle cerebral artery occlusion
    • Aoki Y., Tamura M., Itoh Y., Seto T., Nonaka K., Mukai H., Ukai Y. Cerebroprotective effects of NS-7, a novel pyrimidine derivative, in rats after permanent middle cerebral artery occlusion. J. Pharmacol. Exp. Ther. 296:2001;306-311.
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 306-311
    • Aoki, Y.1    Tamura, M.2    Itoh, Y.3    Seto, T.4    Nonaka, K.5    Mukai, H.6    Ukai, Y.7
  • 3
    • 0035951623 scopus 로고    scopus 로고
    • 2+ channel blocker NS-7 I. Effect on the cerebral infarction and edema at the acute stage of permanent middle cerebral artery occlusion in rats
    • 2+ channel blocker NS-7 I. Effect on the cerebral infarction and edema at the acute stage of permanent middle cerebral artery occlusion in rats. Brain Res. 890:2001;162-169.
    • (2001) Brain Res. , vol.890 , pp. 162-169
    • Aoki, Y.1    Tamura, M.2    Itoh, Y.3    Ukai, Y.4
  • 4
    • 0035951624 scopus 로고    scopus 로고
    • 2+ channel blocker NS-7 II. Effect on the cerebral infraction, behavioral and cognitive impairments at the chronic stage of permanent middle cerebral artery occlusion in rats
    • 2+ channel blocker NS-7 II. Effect on the cerebral infraction, behavioral and cognitive impairments at the chronic stage of permanent middle cerebral artery occlusion in rats. Brain Res. 890:2001;170-176.
    • (2001) Brain Res. , vol.890 , pp. 170-176
    • Tamura, M.1    Aoki, Y.2    Seto, T.3    Itoh, Y.4    Ukai, Y.5
  • 7
    • 0025251185 scopus 로고
    • Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake
    • Szatkowski M., Barbour B., Attwell D. Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Nature. 348:1990;443-446.
    • (1990) Nature , vol.348 , pp. 443-446
    • Szatkowski, M.1    Barbour, B.2    Attwell, D.3
  • 8
    • 0027136017 scopus 로고
    • A new family of neurotransmitter transporters: The high-affinity glutamate transporters
    • Kanai Y., Smith C.P., Hediger M.A. A new family of neurotransmitter transporters: the high-affinity glutamate transporters. FASEB J. 7:1993;1450-1459.
    • (1993) FASEB J. , vol.7 , pp. 1450-1459
    • Kanai, Y.1    Smith, C.P.2    Hediger, M.A.3
  • 9
    • 0028340999 scopus 로고
    • Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate
    • Kiedrowski L., Wroblewski J.T., Costa E. Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate. Mol. Pharmascol. 45:1994;1050-1054.
    • (1994) Mol. Pharmascol. , vol.45 , pp. 1050-1054
    • Kiedrowski, L.1    Wroblewski, J.T.2    Costa, E.3
  • 10
    • 0028325880 scopus 로고
    • Pertubation of intracellular calcium and hydrogen ion regulation in cultured mouse hippocampal neurons by reduction of the sodium ion concentration gradient
    • Koch R.A., Barish M.E. Pertubation of intracellular calcium and hydrogen ion regulation in cultured mouse hippocampal neurons by reduction of the sodium ion concentration gradient. J. Neurosci. 14:1994;2585-2593.
    • (1994) J. Neurosci. , vol.14 , pp. 2585-2593
    • Koch, R.A.1    Barish, M.E.2
  • 12
    • 0033048624 scopus 로고    scopus 로고
    • 2+ channels involving depolarization-stimulated nitric oxide synthase activity in primary neuronal culture
    • 2+ channels involving depolarization-stimulated nitric oxide synthase activity in primary neuronal culture. J. Neurochem. 72:1999;1315-1322.
    • (1999) J. Neurochem. , vol.72 , pp. 1315-1322
    • Oka, M.1    Itoh, Y.2    Ukai, Y.3    Kimura, K.4
  • 13
    • 4243375516 scopus 로고    scopus 로고
    • Modulation by a novel neuroprotective agent (NS-7) of cardiac ion currents
    • Satoh H. Modulation by a novel neuroprotective agent (NS-7) of cardiac ion currents. Jpn. J. Pharmacol. 79(SI):1999;175P.
    • (1999) Jpn. J. Pharmacol. , vol.79 , Issue.SI
    • Satoh, H.1
  • 14
    • 0032918196 scopus 로고    scopus 로고
    • Ks in guinea pig ventricular cardiomyocytes
    • Ks in guinea pig ventricular cardiomyocytes. Br. J. Pharmacol. 126:1999;87-92.
    • (1999) Br. J. Pharmacol. , vol.126 , pp. 87-92
    • Satoh, H.1
  • 15
    • 0024549168 scopus 로고
    • Electrophysiological actions of A23187 and X-537A in spontaneously beating and in voltage-clamped rabbit sino-atrial node preparations
    • Satoh H., Tsuchida K., Hashimoto K. Electrophysiological actions of A23187 and X-537A in spontaneously beating and in voltage-clamped rabbit sino-atrial node preparations. Naunyn-Schmiedeberg's Arch. Pharmacol. 339:1989;320-326.
    • (1989) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.339 , pp. 320-326
    • Satoh, H.1    Tsuchida, K.2    Hashimoto, K.3
  • 20
    • 0034721997 scopus 로고    scopus 로고
    • ks currents in rat sino-atrial nodal cells
    • ks currents in rat sino-atrial nodal cells. Eur. J. Pharmacol. 407:2000;123-129.
    • (2000) Eur. J. Pharmacol. , vol.407 , pp. 123-129
    • Satoh, H.1
  • 21
    • 0022531192 scopus 로고
    • An electrophysiological study of amiloride on sino-atrial node cells and ventricular muscle of rabbit and dog
    • Satoh H., Hashimoto K. An electrophysiological study of amiloride on sino-atrial node cells and ventricular muscle of rabbit and dog. Naunyn-Schmiedeberg's Arch. Pharmacol. 333:1986;83-90.
    • (1986) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.333 , pp. 83-90
    • Satoh, H.1    Hashimoto, K.2
  • 22
    • 0024439938 scopus 로고
    • An electrophysiological comparison between a novel class Ic antiarrhythmic agent, NIK-244 (ethacizin), and flecainide in canine ventricular muscle
    • Satoh H., Ishii M., Hashimoto K. An electrophysiological comparison between a novel class Ic antiarrhythmic agent, NIK-244 (ethacizin), and flecainide in canine ventricular muscle. Br. J. Pharmacol. 98:1989;827-832.
    • (1989) Br. J. Pharmacol. , vol.98 , pp. 827-832
    • Satoh, H.1    Ishii, M.2    Hashimoto, K.3
  • 23
    • 3142600800 scopus 로고
    • Role of calcium in caffeine-norepinephrine interactions in canine Purkinje fibers
    • Satoh H., Vassalle M. Role of calcium in caffeine-norepinephrine interactions in canine Purkinje fibers. Am. J. Physiol. 257:1989;H226-H237.
    • (1989) Am. J. Physiol. , vol.257
    • Satoh, H.1    Vassalle, M.2
  • 24
    • 0030272917 scopus 로고    scopus 로고
    • Cardiac mechanical and electrophysiologic modulations of guinea pig by caffeine and thapsigargin
    • Nario K., Satoh H. Cardiac mechanical and electrophysiologic modulations of guinea pig by caffeine and thapsigargin. Gen. Pharmacol. 27:1996;1227-1235.
    • (1996) Gen. Pharmacol. , vol.27 , pp. 1227-1235
    • Nario, K.1    Satoh, H.2
  • 25
    • 0027298957 scopus 로고
    • Comparative electrophysiological and mechanical actions of ATP-sensitive potassium channel openers in canine Purkinje fibers
    • Satoh H. Comparative electrophysiological and mechanical actions of ATP-sensitive potassium channel openers in canine Purkinje fibers. Gen. Pharmacol. 24:1993;565-575.
    • (1993) Gen. Pharmacol. , vol.24 , pp. 565-575
    • Satoh, H.1
  • 26
    • 0030426273 scopus 로고    scopus 로고
    • 2+-dependence of caffeine modulation of the rate-force relation in canine cardiac Purkinje fibers
    • 2+-dependence of caffeine modulation of the rate-force relation in canine cardiac Purkinje fibers. J. Pharmacol. Exp. Ther. 278:1996;826-835.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 826-835
    • Satoh, H.1    Vassalle, M.2
  • 28
    • 0032555292 scopus 로고    scopus 로고
    • 2+ channel blocker NS-7 inhibits evoked but not spontaneous dopamine release from rat striatum, as measured by intracerebral microdialysis
    • 2+ channel blocker NS-7 inhibits evoked but not spontaneous dopamine release from rat striatum, as measured by intracerebral microdialysis. Neurosci. Lett. 252:1998;203-206.
    • (1998) Neurosci. Lett. , vol.252 , pp. 203-206
    • Itoh, Y.1    Oka, M.2    Ukai, Y.3    Kimura, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.