Identification of p115 as a PLC γ 1-binding protein and the role of Src homology domains of PLC γ 1 in the vesicular transport

Biochemical and Biophysical Research Communications

Volumn 300, Issue 3, 2003, Pages 649-655

  Han, Seung Jin ^a   Lee, Jung Hyun ^a   Kim, Chan Gil ^b   Hong, Seung Hwan ^a  

^a Seoul National University   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

Binding protein; P115; PLC 1; SH2; SH3

Indexed keywords

ALKALINE PHOSPHATASE; ANTISERUM; BINDING PROTEIN; INOSITOL PHOSPHOLIPID SPECIFIC PHOSPHOLIPASE C GAMMA 1; ISOENZYME; PROTEIN P115; REGULATOR PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; HYBRID PROTEIN; MEMBRANE PROTEIN; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; VESICULAR TRANSPORT FACTOR P115; VESICULAR TRANSPORT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE TRANSPORT; CELL VACUOLE; CONTROLLED STUDY; ENZYME RELEASE; GENE DELETION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; SEQUENCE HOMOLOGY; ANIMAL; BRAIN LEVEL; CELL LINE; CELL STRAIN; CHEMISTRY; ENZYME SPECIFICITY; GENETIC TRANSFECTION; GENETICS; HUMAN; IMMUNOBLOTTING; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; SERODIAGNOSIS; SRC HOMOLOGY DOMAIN; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; BRAIN CHEMISTRY; CARRIER PROTEINS; CELL LINE; HUMANS; IMMUNOBLOTTING; ISOENZYMES; MEMBRANE PROTEINS; PC12 CELLS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PRECIPITIN TESTS; PROTEIN BINDING; RATS; RECOMBINANT FUSION PROTEINS; SRC HOMOLOGY DOMAINS; SUBSTRATE SPECIFICITY; TRANSFECTION; VESICULAR TRANSPORT PROTEINS;

EID: 0037449349     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02884-X     Document Type: Article

References (30)

1. Ji Q.S., Winnier G.E., Niswender K.D., Horstman D., Wisdom R., Magnuson M.A., Carpenter G. Essential role of the tyrosine kinase substrate phospholipase C-. γ 1 in mammalian growth and development Proc. Natl. Acad. Sci. USA. 94:1997;2999-3003.
2. Rhee S.G., Choi K.D. Multiple forms of phospholipase C isozymes and their activation mechanisms. Adv. Second Messenger Phosphoprotein Res. 26:1992;35-61.
3. Pawson T. Protein modules and signalling networks. Nature. 373:1995;573-580.
4. Chang J.S., Noh D.Y., Park I.A., Kim M.J., Song H., Ryu S.H., Suh P.G. Overexpression of phospholipase C-. γ 1 in rat 3Y1 fibroblast cells leads to malignant transformation Cancer Res. 57:1997;5465-5468.
5. Sztul E. Transcytotic vesicle fusion with plasma membrane. Methods Enzymol. 219:1992;44-51.
6. Alvarez C., Fujita H., Hubbard A., Sztul E. ER to Golgi transport: requirement for p115 at a pre-Golgi VTC stage. J. Cell Biol. 147:1999;1205-1222.
7. Seemann J., Jokitalo E.J., Warren G. The role of the tethering proteins p115 and GM130 in transport through the Golgi apparatus in vivo. Mol. Biol. Cell. 11:2000;635-645.
8. De Camilli P., Emr S.D., McPherson P.S., Novick P. Phosphoinositides as regulators in membrane traffic. Science. 271:1996;1533-1539.
9. Ahn S.J., Han S.J., Mo H.J., Chung J.K., Hong S.H., Park T.K., Kim C.G. Interaction of phospholipase C. γ 1 via its COOH-terminal SRC homology 2 domain with synaptojanin Biochem. Biophys. Res. Commun. 244:1998;62-67. doi: 10.1006/bbrc.2001.6154.
10. Han S.J., Lee J.H., Hong S.H., Park S.D., Kim C.G., Song M.D., Park T.K., Kim C.G. AP180 binds to the C-terminal SH2 domain of phospholipase C-. γ 1 and inhibits its enzymatic activity Biochem. Biophys. Res. Commun. 290:2002;35-41. doi: 10.1006/bbrc.1998.8220.
11. Bae S.S., Lee Y.H., Chang J.S., Galadari S.H., Kim Y.S., Ryu S.H., Suh P.G. Src homology domains of phospholipase C. γ 1 inhibit nerve growth factor-induced differentiation of PC12 cells J. Neurochem. 71:1998;178-185.
12. Waters M.G., Clary D.O., Rothman J.E. A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack. J. Cell. Biol. 118:1992;1015-1026.
13. Kuhn U., Cohn D.V., Gorr S.U. Polarized secretion of the regulated secretory protein chromogranin A. Biochem. Biophys. Res. Commun. 270:1998;631-636. doi:10.1006/bbrc.2000.2469.
14. Onofri F., Giovedi S., Kao H.T., Valtorta F., Borbone L.B., De Camilli P., Greengard P., Benfenati F. Specificity of the binding of synapsin I to Src homology 3 domains. J. Biol. Chem. 275:2000;29857-29867.
15. Shorter J., Warren G. A role for the vesicle tethering protein, p115, in the post-mitotic stacking of reassembling Golgi cisternae in a cell-free system. J. Cell. Biol. 146:1999;57-70.
16. Moyer B.D., Allan B.B., Balch W.E. Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis-Golgi tethering. Traffic. 2:2001;268-276.
17. Liscovitch M., Czarny M., Fiucci G., Lavie Y., Tang X. Localization and possible functions of phospholipase D isozymes. Biochim. Biophys. Acta. 1439:1999;245-263.
18. Olivos-Glander I.M., Janne P.A., Nussbaum R.L. The oculocerebrorenal syndrome gene product is a 105-kD protein localized to the Golgi complex. Am. J. Hum. Genet. 57:1995;817-823.
19. Jones G.A., Carpenter G. The regulation of phospholipase C-. γ 1 by phosphatidic acid. Assessment of kinetic parameters J. Biol. Chem. 268:1993;20845-20850.
20. 2 on the Golgi complex Nat. Cell Biol. 1:1999;280-287.
21. Gilmore A.P., Burridge K. Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate. Nature. 381:1996;531-535.
22. 2 -binding proteins involved in signaling by tyrosine kinase J. Biol. Chem. 269:1994;1518-1522.
23. Janmey P.A., Xian W., Flanagan L.A. Controlling cytoskeleton structure by phosphoinositide-protein interactions: phosphoinositide binding protein domains and effects of lipid packing. Chem. Phys. Lipids. 101:1999;93-107.
24. Lin K.M., Wenegieme E., Lu P.J., Chen C.S., Yin H.L. Gelsolin binding to phosphatidylinositol 4,5-bisphosphate is modulated by calcium and pH. J. Biol. Chem. 272:1997;20443-20450.
25. Feldman D.A., Weinhold P.A. Cytidylyltransferase-binding protein is identical to transcytosis-associated protein (TAP/p115) and enhances the lipid activation of cytidylyltransferase. J. Biol. Chem. 273:1998;102-109.
26. Fernandez-Tome M.C., Speziale E.H., Sterin-Speziale N.B. Phospholipase C inhibitors and prostaglandins differentially regulate phosphatidylcholine synthesis in rat renal papilla. Evidence of compartmental regulation of CTP:phosphocholine cytidylyltransferase and CDP-choline:1,2-diacylglycerol cholinephosphotransferase. Biochim. Biophys. Acta. 1583:2002;185-194.
27. Simonsen A., Lippe R., Christoforidis S., Gaullier J.M., Brech A., Callaghan J., Toh B.H., Murphy C., Zerial M., Stenmark H. EEA1 links PI(3)K function to Rab5 regulation of endosome fusion. Nature. 394:1998;494-498.
28. Allan B.B., Moyer B.D., Balch W.E. Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science. 289:2000;444-448.
29. Ye K., Aghdasi B., Luo H.R., Moriarity J.L., Wu F.Y., Hong J.J., Hurt K.J., Bae S.S., Suh P.G., Snyder S.H. Phospholipase C. γ 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE Nature. 415:2002;541-544.
30. McPherson P.S. Regulatory role of SH3 domain-mediated protein-protein interactions in synaptic vesicle endocytosis. Cell Signal. 11:1999;229-238.