Mutation of active site residues of the puromycin-sensitive aminopeptidase: Conversion of the enzyme into a catalytically inactive binding protein

Archives of Biochemistry and Biophysics

Volumn 413, Issue 2, 2003, Pages 236-242

  Thompson, Michael W ^a   Govindaswami, Meera ^a   Hersh, Louis B ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Catalytic residues; Mutagenesis; Reaction mechanism; Substrate binding

Indexed keywords

2 NAPHTHYLAMINE; ALANINE; AMINOPEPTIDASE; BINDING PROTEIN; DYNORPHIN[1-9]; GLUTAMIC ACID; GLUTAMINE; PHENYLALANINE; PUROMYCIN; TYROSINE; VALINE;

ARTICLE; BINDING AFFINITY; CATALYSIS; CATALYST; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SUBSTRATE; MUTATION; PRIORITY JOURNAL; PROTEIN BINDING;

EID: 0037447922     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9861(03)00123-1     Document Type: Article

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