메뉴 건너뛰기




Volumn 209, Issue 1-2, 2003, Pages 31-39

Cellular compartmentalization of phosphorylated eIF2α and neuronal NOS in human temporal lobe epilepsy with hippocampal sclerosis

Author keywords

Glia; Hippocampus; Immunocytochemistry; NADPH D; Neurons

Indexed keywords

CARBAMAZEPINE; INITIATION FACTOR 2; INITIATION FACTOR 2ALPHA; LAMOTRIGINE; NITRIC OXIDE SYNTHASE; PHENYTOIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; TOPIRAMATE; UNCLASSIFIED DRUG;

EID: 0037447742     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(02)00461-6     Document Type: Article
Times cited : (15)

References (55)
  • 1
    • 0001855752 scopus 로고
    • Pathological findings in epilepsy
    • J. Jr. Engel. New York: Raven Press
    • Babb T.L., Brown W.J. Pathological findings in epilepsy. Engel J. Jr. Surgical treatment of the epilepsies. 1987;511-540 Raven Press, New York.
    • (1987) Surgical treatment of the epilepsies , pp. 511-540
    • Babb, T.L.1    Brown, W.J.2
  • 2
    • 0013950709 scopus 로고
    • Epilepsy and the temporal lobes. A clinical, electroencephalographic, neuropathological study of the brain in epilepsy with particular reference to the temporal lobes
    • Margerison J.H., Corsellis J.A.N. Epilepsy and the temporal lobes. A clinical, electroencephalographic, neuropathological study of the brain in epilepsy with particular reference to the temporal lobes. Brain. 89:1966;499-530.
    • (1966) Brain , vol.89 , pp. 499-530
    • Margerison, J.H.1    Corsellis, J.A.N.2
  • 5
    • 0023191694 scopus 로고
    • Hippocampal neuron loss in temporal lobe epilepsy: Correlation with early childhood convulsions
    • Sager H.J., Oxbury J.M. Hippocampal neuron loss in temporal lobe epilepsy: correlation with early childhood convulsions. Ann. Neurol. 22:1987;334-340.
    • (1987) Ann. Neurol. , vol.22 , pp. 334-340
    • Sager, H.J.1    Oxbury, J.M.2
  • 6
    • 0027173125 scopus 로고
    • Early childhood prolonged febrile convulsions, atrophy and sclerosis of mesial structures, and temporal lobe epilepsy: An MRI volumetric study
    • Cendes F., Andermann F., Dubeau F.et al. Early childhood prolonged febrile convulsions, atrophy and sclerosis of mesial structures, and temporal lobe epilepsy: an MRI volumetric study. Neurology. 43:1993;1083-1087.
    • (1993) Neurology , vol.43 , pp. 1083-1087
    • Cendes, F.1    Andermann, F.2    Dubeau, F.3
  • 7
    • 0032933248 scopus 로고    scopus 로고
    • Neuroimaging evidence of progressive neuronal loss and dysfunction in temporal lobe epilepsy
    • Tasch E., Cendes F., Li L.M., Dubeau F., Andermann F., Arnold D.L. Neuroimaging evidence of progressive neuronal loss and dysfunction in temporal lobe epilepsy. Ann. Neurol. 45:1999;569-576.
    • (1999) Ann. Neurol. , vol.45 , pp. 569-576
    • Tasch, E.1    Cendes, F.2    Li, L.M.3    Dubeau, F.4    Andermann, F.5    Arnold, D.L.6
  • 8
    • 0032947306 scopus 로고    scopus 로고
    • Hippocampal atrophy, epilepsy duration, and febrile seizures in patients with partial seizures
    • Theodore W.H., Bhatia S., Hatta J.et al. Hippocampal atrophy, epilepsy duration, and febrile seizures in patients with partial seizures. Neurology. 52:1999;132-136.
    • (1999) Neurology , vol.52 , pp. 132-136
    • Theodore, W.H.1    Bhatia, S.2    Hatta, J.3
  • 9
    • 0029905417 scopus 로고    scopus 로고
    • Relationship of hippocampal sclerosis to duration and age of onset of epilepsy, and childhood febrile seizures in temporal lobectomy patients
    • Davies K.G., Hermann B.P., Dohan F.C., Foley K.T., Bush A.J., Wyler A.R. Relationship of hippocampal sclerosis to duration and age of onset of epilepsy, and childhood febrile seizures in temporal lobectomy patients. Epilepsy Res. 24:1996;119-126.
    • (1996) Epilepsy Res. , vol.24 , pp. 119-126
    • Davies, K.G.1    Hermann, B.P.2    Dohan, F.C.3    Foley, K.T.4    Bush, A.J.5    Wyler, A.R.6
  • 10
    • 0027438214 scopus 로고
    • Atrophy of mesial structures in patients with temporal lobe epilepsy: Cause or consequence of repeated seizures?
    • Cendes F., Andermann F., Gloor P.et al. Atrophy of mesial structures in patients with temporal lobe epilepsy: cause or consequence of repeated seizures? Ann. Neurol. 34:1993;795-801.
    • (1993) Ann. Neurol. , vol.34 , pp. 795-801
    • Cendes, F.1    Andermann, F.2    Gloor, P.3
  • 11
    • 0027185758 scopus 로고
    • Quantitative MRI hippocampal volumes: Association with onset and duration of epilepsy, and febrile convulsions in temporal lobectomy patients
    • Trenerry M.R., Jack C.R., Sharbrough F.W.et al. Quantitative MRI hippocampal volumes: association with onset and duration of epilepsy, and febrile convulsions in temporal lobectomy patients. Epilepsy Res. 15:1993;247-252.
    • (1993) Epilepsy Res. , vol.15 , pp. 247-252
    • Trenerry, M.R.1    Jack, C.R.2    Sharbrough, F.W.3
  • 12
    • 0017370502 scopus 로고
    • Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis
    • Farrell P.J., Balkow K., Hunt T., Jackson R.J., Trachsel H. Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis. Cell. 11:1977;187-200.
    • (1977) Cell , vol.11 , pp. 187-200
    • Farrell, P.J.1    Balkow, K.2    Hunt, T.3    Jackson, R.J.4    Trachsel, H.5
  • 13
    • 0023878562 scopus 로고
    • The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2
    • Rowlands A.G., Montine K.S., Henshaw E.C., Panniers R. The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2. J. Biol. Chem. 263:1988;5526-5533.
    • (1988) J. Biol. Chem. , vol.263 , pp. 5526-5533
    • Rowlands, A.G.1    Montine, K.S.2    Henshaw, E.C.3    Panniers, R.4
  • 14
    • 0030669910 scopus 로고    scopus 로고
    • Effect of brain ischemia and reperfusion on the localization of phosphorylated eukaryotic initiation factor 2 alpha
    • DeGracia D.J., Sullivan J.M., Neumar R.W., Alousi S.S., Hikade K.R., Pittman J.E.et al. Effect of brain ischemia and reperfusion on the localization of phosphorylated eukaryotic initiation factor 2 alpha. J. Cereb. Blood Flow Metab. 17:1997;1291-1302.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 1291-1302
    • DeGracia, D.J.1    Sullivan, J.M.2    Neumar, R.W.3    Alousi, S.S.4    Hikade, K.R.5    Pittman, J.E.6
  • 15
    • 0032848468 scopus 로고    scopus 로고
    • Ultrastructural localization of phosphorylated eIF2alpha (eIF2alphaP) in rat dorsal hippocampus during reperfusion
    • Goldstein E.N., Owen C., White B.C., Rafols J.A. Ultrastructural localization of phosphorylated eIF2alpha (eIF2alphaP) in rat dorsal hippocampus during reperfusion. Acta Neuropathol. 98:1999;493-505.
    • (1999) Acta Neuropathol. , vol.98 , pp. 493-505
    • Goldstein, E.N.1    Owen, C.2    White, B.C.3    Rafols, J.A.4
  • 16
    • 0034889683 scopus 로고    scopus 로고
    • Upregulation of iNOS and eIF-2α(P) expression is paralleled by suppression of protein synthesis in the hypothalamus following trauma to the brain
    • Petrov T., Underwood B., Alousi S., Owen S., Rafols J.A. Upregulation of iNOS and eIF-2α(P) expression is paralleled by suppression of protein synthesis in the hypothalamus following trauma to the brain. J. Neurotrauma. 98:2001;799-812.
    • (2001) J. Neurotrauma , vol.98 , pp. 799-812
    • Petrov, T.1    Underwood, B.2    Alousi, S.3    Owen, S.4    Rafols, J.A.5
  • 17
    • 0000362398 scopus 로고    scopus 로고
    • Localization of phosphorylated eukaryotic initiation factor 2 alpha in hippocampus after traumatic brain injury
    • Rafols J.A., White B.C., Francis T., Petrov T., Underwood B.D. Localization of phosphorylated eukaryotic initiation factor 2 alpha in hippocampus after traumatic brain injury. Soc. Neurosci. (Abstr.). 27(1):2001;568.
    • (2001) Soc. Neurosci. (Abstr.) , vol.27 , Issue.1 , pp. 568
    • Rafols, J.A.1    White, B.C.2    Francis, T.3    Petrov, T.4    Underwood, B.D.5
  • 18
    • 0034996080 scopus 로고    scopus 로고
    • Brain ischemia and reperfusion activate the eukaryotic initiation factor 2alpha kinase, PERK
    • Kumar R., Azam S., Sullivan J.M., Owen C., Cavener D.R., Zhang P.et al. Brain ischemia and reperfusion activate the eukaryotic initiation factor 2alpha kinase, PERK. J. Neurochem. 77:2001;1418-1421.
    • (2001) J. Neurochem. , vol.77 , pp. 1418-1421
    • Kumar, R.1    Azam, S.2    Sullivan, J.M.3    Owen, C.4    Cavener, D.R.5    Zhang, P.6
  • 19
    • 0033198188 scopus 로고    scopus 로고
    • Reactive oxygen species mediate activity-dependent neuron-glia signaling in output fibers of the hippocampus
    • Atkins C.M., Sweatt J.D. Reactive oxygen species mediate activity-dependent neuron-glia signaling in output fibers of the hippocampus. J. Neurosci. 9:1999;7241-7248.
    • (1999) J. Neurosci. , vol.9 , pp. 7241-7248
    • Atkins, C.M.1    Sweatt, J.D.2
  • 20
    • 0032704101 scopus 로고    scopus 로고
    • Antioxidants, oxidative stress, and degenerative neurological disorders
    • Floyd R.A. Antioxidants, oxidative stress, and degenerative neurological disorders. Proc. Soc. Exp. Med. 222:1999;236-245.
    • (1999) Proc. Soc. Exp. Med. , vol.222 , pp. 236-245
    • Floyd, R.A.1
  • 21
    • 0031902602 scopus 로고    scopus 로고
    • Inhibition of protein synthesis by nitric oxide correlates with cytostatic activity: Nitric oxide induces phosphorylation of initiation factor eIF-2 alpha
    • Kim Y.M., Son K., Hong S.J., Green A., Chen J.J., Tzeng E.et al. Inhibition of protein synthesis by nitric oxide correlates with cytostatic activity: nitric oxide induces phosphorylation of initiation factor eIF-2 alpha. Mol. Med. 4:1998;179-190.
    • (1998) Mol. Med. , vol.4 , pp. 179-190
    • Kim, Y.M.1    Son, K.2    Hong, S.J.3    Green, A.4    Chen, J.J.5    Tzeng, E.6
  • 22
    • 0031022039 scopus 로고    scopus 로고
    • Localization of neuronal and endothelial nitric oxide synthase isoforms in human hippocampus
    • Doyle C.A., Slater P. Localization of neuronal and endothelial nitric oxide synthase isoforms in human hippocampus. Neuroscience. 76:1997;387-395.
    • (1997) Neuroscience , vol.76 , pp. 387-395
    • Doyle, C.A.1    Slater, P.2
  • 24
    • 0040510653 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase (nNOS) mRNA expression and NADPH-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and Alzheimer's disease brains
    • Norris P.J., Faull R.L., Emson P.C. Neuronal nitric oxide synthase (nNOS) mRNA expression and NADPH-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and Alzheimer's disease brains. Mol. Brain Res. 41:1996;36-49.
    • (1996) Mol. Brain Res. , vol.41 , pp. 36-49
    • Norris, P.J.1    Faull, R.L.2    Emson, P.C.3
  • 26
    • 0026671313 scopus 로고
    • Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging
    • Watson C., Andermann F., Gloor P.et al. Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging. Neurology. 42:1992;1743-1750.
    • (1992) Neurology , vol.42 , pp. 1743-1750
    • Watson, C.1    Andermann, F.2    Gloor, P.3
  • 27
    • 0030808772 scopus 로고    scopus 로고
    • Volumetric magnetic resonance imaging: Clinical applications and contributions to the understanding of temporal lobe epilepsy
    • Watson C., Jack C.R., Cendes F. Volumetric magnetic resonance imaging: clinical applications and contributions to the understanding of temporal lobe epilepsy. Arch. Neurol. 54:1997;1521-1531.
    • (1997) Arch. Neurol. , vol.54 , pp. 1521-1531
    • Watson, C.1    Jack, C.R.2    Cendes, F.3
  • 28
    • 0031053579 scopus 로고    scopus 로고
    • Specificity of volumetric magnetic resonance imaging in detecting hippocampal sclerosis
    • Watson C., Cendes F., Fuerst D.et al. Specificity of volumetric magnetic resonance imaging in detecting hippocampal sclerosis. Arch. Neurol. 54:1997;67-73.
    • (1997) Arch. Neurol. , vol.54 , pp. 67-73
    • Watson, C.1    Cendes, F.2    Fuerst, D.3
  • 29
    • 0029917254 scopus 로고    scopus 로고
    • Pathological grading system for hippocampal sclerosis: Correlation with magnetic resonance imaging-based volume measurements of the hippocampus
    • Watson C., Nielsen S.L., Cobb C., Burgerman R., Williamson B. Pathological grading system for hippocampal sclerosis: correlation with magnetic resonance imaging-based volume measurements of the hippocampus. J. Epilepsy. 9:1996;56-64.
    • (1996) J. Epilepsy , vol.9 , pp. 56-64
    • Watson, C.1    Nielsen, S.L.2    Cobb, C.3    Burgerman, R.4    Williamson, B.5
  • 30
    • 0026442588 scopus 로고
    • A grading system for mesial temporal pathology (hippocampal sclerosis) from anterior temporal lobectomy
    • Wyler A.R., Dohan F.C., Schweitzer J.B., Berry A.D. A grading system for mesial temporal pathology (hippocampal sclerosis) from anterior temporal lobectomy. J. Epilepsy. 5:1992;220-225.
    • (1992) J. Epilepsy , vol.5 , pp. 220-225
    • Wyler, A.R.1    Dohan, F.C.2    Schweitzer, J.B.3    Berry, A.D.4
  • 31
    • 0028978834 scopus 로고
    • Hypotension induces c-fos expression in NADPH-diaphorase positive hypothalamic neurons
    • Petrov T., Harris K.H., McTavish D., Krukoff T.L., Jhamandas J.H. Hypotension induces c-fos expression in NADPH-diaphorase positive hypothalamic neurons. Neuropharmacology. 34:1995;509-514.
    • (1995) Neuropharmacology , vol.34 , pp. 509-514
    • Petrov, T.1    Harris, K.H.2    McTavish, D.3    Krukoff, T.L.4    Jhamandas, J.H.5
  • 32
    • 0030451938 scopus 로고    scopus 로고
    • Activation of nitric oxide synthesizing neurons during precipitated morphine withdrawal
    • Jhamandas J.H., Harris K.H., Petrov T., Jhamandas K.H. Activation of nitric oxide synthesizing neurons during precipitated morphine withdrawal. NeuroReport. 7:1996;2843-2846.
    • (1996) NeuroReport , vol.7 , pp. 2843-2846
    • Jhamandas, J.H.1    Harris, K.H.2    Petrov, T.3    Jhamandas, K.H.4
  • 34
    • 70449320100 scopus 로고
    • Clinico-pathological considerations of temporal lobe epilepsy due to small focal lesions
    • Falconer M.A., Cavanagh J.B. Clinico-pathological considerations of temporal lobe epilepsy due to small focal lesions. Brain. 82:1959;404-483.
    • (1959) Brain , vol.82 , pp. 404-483
    • Falconer, M.A.1    Cavanagh, J.B.2
  • 36
    • 0024412565 scopus 로고
    • Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy
    • deLamerolle N.C., Kim J.H., Robbins R.J., Spencer D.D. Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy. Brain Res. 495:1989;387-395.
    • (1989) Brain Res. , vol.495 , pp. 387-395
    • DeLamerolle, N.C.1    Kim, J.H.2    Robbins, R.J.3    Spencer, D.D.4
  • 37
    • 0025978935 scopus 로고
    • A selective loss of somatostatin in the hippocampus of patients with temporal lobe epilepsy
    • Robbins R.J., Brines M.L., Kim J.H., Adrian T., deLamerolle N.C., Welsh S.et al. A selective loss of somatostatin in the hippocampus of patients with temporal lobe epilepsy. Ann. Neurol. 29:1992;325-332.
    • (1992) Ann. Neurol. , vol.29 , pp. 325-332
    • Robbins, R.J.1    Brines, M.L.2    Kim, J.H.3    Adrian, T.4    DeLamerolle, N.C.5    Welsh, S.6
  • 38
    • 0029013993 scopus 로고
    • Reactive synaptogenesis and neuron densities for neuropeptide Y, somato-statin, and glutamate decarboxylase immunoreactivity in the epileptogenic human fascia dentata
    • Mathern G.W., Babb T.L., Pretorius J.K., Leite J.P. Reactive synaptogenesis and neuron densities for neuropeptide Y, somato-statin, and glutamate decarboxylase immunoreactivity in the epileptogenic human fascia dentata. J. Neurosci. 15:1995;3990-4004.
    • (1995) J. Neurosci. , vol.15 , pp. 3990-4004
    • Mathern, G.W.1    Babb, T.L.2    Pretorius, J.K.3    Leite, J.P.4
  • 40
    • 0025022424 scopus 로고
    • Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy
    • Houser C.R., Miyashiro J.E., Swartz B.E., Walsh G.O., Rich J.R., Delgado-Escueta A.V. Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy. J. Neurosci. 10:1990;267-282.
    • (1990) J. Neurosci. , vol.10 , pp. 267-282
    • Houser, C.R.1    Miyashiro, J.E.2    Swartz, B.E.3    Walsh, G.O.4    Rich, J.R.5    Delgado-Escueta, A.V.6
  • 41
    • 0028870168 scopus 로고
    • Quantified patterns of mossy fiber sprouting and neuron densities in hippocampal and lesional seizures
    • Mathern G.W., Pretorius J.K., Babb T.L. Quantified patterns of mossy fiber sprouting and neuron densities in hippocampal and lesional seizures. J. Neurosurg. 82:1995;211-219.
    • (1995) J. Neurosurg. , vol.82 , pp. 211-219
    • Mathern, G.W.1    Pretorius, J.K.2    Babb, T.L.3
  • 42
    • 0024444281 scopus 로고
    • Mossy fiber synaptic reorganization in the epileptic human temporal lobe
    • Sutula T., Cascino G., Cavazos J., Parada I., Ramirez L. Mossy fiber synaptic reorganization in the epileptic human temporal lobe. Ann. Neurol. 26:1989;321-330.
    • (1989) Ann. Neurol. , vol.26 , pp. 321-330
    • Sutula, T.1    Cascino, G.2    Cavazos, J.3    Parada, I.4    Ramirez, L.5
  • 43
    • 0031843207 scopus 로고    scopus 로고
    • Glutamate receptor subunits GluR2 and GluR2/3 distribution shows reorganization in the human epileptogenic hippocampus
    • deLamerolle N.C., Eid T., vonCampe G.et al. Glutamate receptor subunits GluR2 and GluR2/3 distribution shows reorganization in the human epileptogenic hippocampus. Eur. J. Neurosci. 10:1998;1687-1703.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 1687-1703
    • DeLamerolle, N.C.1    Eid, T.2    VonCampe, G.3
  • 44
    • 17444454773 scopus 로고    scopus 로고
    • Increased hippocampal AMPA and NMDA receptor subunit immunoreactivity in temporal lobe epilepsy patients
    • Mathern G.W., Pretorius J.K., Mendoza D.et al. Increased hippocampal AMPA and NMDA receptor subunit immunoreactivity in temporal lobe epilepsy patients. J. Neuropathol. Exp. Neurol. 57:1998;615-634.
    • (1998) J. Neuropathol. Exp. Neurol. , vol.57 , pp. 615-634
    • Mathern, G.W.1    Pretorius, J.K.2    Mendoza, D.3
  • 45
    • 0028179659 scopus 로고
    • Cellular and molecular basis of epilepsy
    • McNamara J.O. Cellular and molecular basis of epilepsy. J. Neurosci. 14:1994;3413-3425.
    • (1994) J. Neurosci. , vol.14 , pp. 3413-3425
    • McNamara, J.O.1
  • 46
    • 0028359677 scopus 로고
    • The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy
    • Sloviter R.S. The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy. Ann. Neurol. 35:1994;640-654.
    • (1994) Ann. Neurol. , vol.35 , pp. 640-654
    • Sloviter, R.S.1
  • 47
    • 0023253616 scopus 로고
    • Early loss of somatostatin neurons in dentate hilus after cerebral ischemia in the rat precedes CA1 pyramidal cell loss
    • Johansen F.F., Zimmer J., Diemer N.H. Early loss of somatostatin neurons in dentate hilus after cerebral ischemia in the rat precedes CA1 pyramidal cell loss. Acta Neuropathol. 73:1987;110-114.
    • (1987) Acta Neuropathol. , vol.73 , pp. 110-114
    • Johansen, F.F.1    Zimmer, J.2    Diemer, N.H.3
  • 48
    • 0026488694 scopus 로고
    • Selective vulnerability of dentate hilar neurons following traumatic brain injury: A potential mechanistic link between head trauma and disorders of the hippocampus
    • Lowenstein D.H., Thomas M.J., Smith D.H., McIntosh T.K. Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus. J. Neurosci. 12:1992;4846-4853.
    • (1992) J. Neurosci. , vol.12 , pp. 4846-4853
    • Lowenstein, D.H.1    Thomas, M.J.2    Smith, D.H.3    McIntosh, T.K.4
  • 50
    • 0029003311 scopus 로고
    • Global brain ischemia and reperfusion: Golgi apparatus ultrastructure in neurons selectively vulnerable to death
    • Rafols J.A., Daya A.M., O'Neil B.J., Krause G.S., Neumar R.W., White B.C. Global brain ischemia and reperfusion: Golgi apparatus ultrastructure in neurons selectively vulnerable to death. Acta Neuropathol. 90:1995;17-30.
    • (1995) Acta Neuropathol. , vol.90 , pp. 17-30
    • Rafols, J.A.1    Daya, A.M.2    O'Neil, B.J.3    Krause, G.S.4    Neumar, R.W.5    White, B.C.6
  • 51
    • 0348113993 scopus 로고    scopus 로고
    • High doses of insulin do not prevent dephosphorylation of eIF2αP, recovery of protein synthesis, and atrophy of hippocampal CA3 neurons during reperfusion
    • Rafols J.A., Alousi S.S., Owen C.R., White B.C., Sullivan J.M. High doses of insulin do not prevent dephosphorylation of eIF2αP, recovery of protein synthesis, and atrophy of hippocampal CA3 neurons during reperfusion. J. Cereb. Blood Flow Metab. 19(Suppl. 1):1999;S511.
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , Issue.SUPPL. 1 , pp. 511
    • Rafols, J.A.1    Alousi, S.S.2    Owen, C.R.3    White, B.C.4    Sullivan, J.M.5
  • 52
    • 85031204498 scopus 로고    scopus 로고
    • Traumatic brain injury induces biphasic phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF2alpha) in cortical neurons: The second phase follows cytoplasmic release of cytochrome c
    • in press
    • Underwood BD, Francis T, Owen CR, Miller JM, Gryzbowski M, McAllister JP, et al. Traumatic brain injury induces biphasic phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF2alpha) in cortical neurons: the second phase follows cytoplasmic release of cytochrome c. J Neurotrauma (in press).
    • J Neurotrauma
    • Underwood, B.D.1    Francis, T.2    Owen, C.R.3    Miller, J.M.4    Gryzbowski, M.5    McAllister, J.P.6
  • 53
    • 0031891869 scopus 로고    scopus 로고
    • Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase
    • Srivastava S.P., Kumar K.U., Kaufman R.J. Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase. J. Biol. Chem. 273:1998;2416-2423.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2416-2423
    • Srivastava, S.P.1    Kumar, K.U.2    Kaufman, R.J.3
  • 54
    • 0031882897 scopus 로고    scopus 로고
    • Nitric oxide causes glutamate release from brain synaptosomes
    • McNaught K.S.P., Brown G.C. Nitric oxide causes glutamate release from brain synaptosomes. J. Neurochem. 70:1998;1541-1546.
    • (1998) J. Neurochem. , vol.70 , pp. 1541-1546
    • McNaught, K.S.P.1    Brown, G.C.2
  • 55
    • 0035116383 scopus 로고    scopus 로고
    • Changes in nitric oxide synthesis and epileptic activity in the contralateral hippocampus of rats following intrahippocampal kainate injection
    • Yasuda H., Fujii M., Fujisawa H., Ito H., Suzuki M. Changes in nitric oxide synthesis and epileptic activity in the contralateral hippocampus of rats following intrahippocampal kainate injection. Epilepsia. 42:2001;13-20.
    • (2001) Epilepsia , vol.42 , pp. 13-20
    • Yasuda, H.1    Fujii, M.2    Fujisawa, H.3    Ito, H.4    Suzuki, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.