Immunobiological effects of AFB1 and AFB1-FB1 mixture in experimental subchronic mycotoxicoses in rats

Toxicology

Volumn 186, Issue 1-2, 2003, Pages 159-170

  Theumer, M G ^a   Lopez A G ^a   Masih, D T ^a   Chulze, S N ^b   Rubinstein, H R ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^b DEPARTAMENTO DE QUÍMICA   (Argentina)

Author keywords

Aflatoxin; Fumonisin; Immunomodulation; Mycotoxicose; Mycotoxins

Indexed keywords

AFLATOXIN B1; FUMONISIN B1; HYDROGEN PEROXIDE; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MYCOTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CONTROLLED STUDY; DIETARY INTAKE; DISEASE SEVERITY; FEEDING; FOOD COMPOSITION; IMMUNOBIOLOGY; IMMUNOMODULATION; IN VITRO STUDY; MALE; MITOGENESIS; MONONUCLEAR CELL; MYCOTOXICOSIS; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; SPLEEN CELL;

AFLATOXIN B1; ALKALINE PHOSPHATASE; ANIMALS; BODY WEIGHT; EATING; FUMONISINS; HYDROGEN PEROXIDE; INTERLEUKINS; MALE; MYCOTOXICOSIS; RATS; RATS, WISTAR; SPLEEN;

ANIMALIA; ZEA MAYS;

EID: 0037447590     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(02)00603-0     Document Type: Article

References (42)

1. Adebajo L.O., Idowu A.A., Adesanya O.O. Mycoflora, and mycotoxins production in Nigerian corn and corn-based snacks. Mycopathologia. 126:1994;183-192.
2. Ali N., Sardjono, Yamashita A., Yoshizawa T. Natural co-occurrence of aflatoxins and Fusarium mycotoxins (fumonisins, deoxynivalenol, nivalenol and zearalenone) in corn from Indonesia. Food Additive Contaminants. 15:1998;377-384.
3. Arai K., Lee F., Miyajima A., Miyatake S., Arai N., Yokota T. Cytokines: co-ordinators of immune and inflammatory responses. Annual Review of Biochemistry. 59:1990;783-836.
4. Bondy G.S., Petska J.J. Immunomodulation by fungal toxins. Journal of Toxicology and Environmental Health. 3:2000;109-143.
5. Casado J.M., Theumer M., Masih D.T., Chulze S., Rubinstein H.R. Experimental subchronic mycotoxicoses in mice: individual and combined effects of fumonisins and aflatoxin B1. Food and Chemical Toxicology. 39:2001;579-586.
6. Chen W.F., Zlotnik A. IL-10: a novel cytotoxic T cell differentiation factor. Journal of Immunology. 147:1991;528-534.
7. Colvin B.M., Harrison L.R. Fumonisin-induced pulmonary edema and hydrothorax in swine. Mycopathologia. 117:1992;79-82.
8. Dalcero A., Magnoli C., Chiacchiera S., Palacios G., Reynoso M. Mycoflora and incidence of aflatoxin B1, zearalenone and deoxynivalenol in poultry feeds in Argentina. Mycopathologia. 137:1997;179-184.
9. Dalcero A., Magnoli C., Luna M., Ancasi G., Reynoso M.M., Chiacchiera S., Miazzo R., Palacio G. Mycoflora and naturally occurring mycotoxins in poultry feeds in Argentina. Mycopathologia. 141:1998;37-43.
10. da Silva J.B., Pozzi C.R., Mallozzi M.A., Ortega E.M., Correa B. Mycoflora and occurrence of aflatoxin B(1) during storage of Brazilian sorghum. Journal of Agriculture and Food Chemistry. 48:2000;4352-4356.
11. Dimitri R.A., Gabal M.A., Saleh N. Effect of aflatoxin ingestion in feed on body weight gain and tissue residues in rabbits. Mycoses. 41:1998;87-91.
12. Etcheverry M., Nesci A., Barros G., Torres A., Chulze S. Occurrence of Aspergillus section flavi and aflatoxin B1 in corn genotypes and corn meal in Argentina. Mycopathologia. 147:1999;37-41.
13. Findor J.A., Bruch Igartua E., Domecq R.B. Enzimas en enfermedades hepáticas. García P. Enfermedades del hígado. 1982;44-56 Buenos Aires, Argentina.
14. Gelderblom W.C., Cawood M.E., Snyman S.D., Marasas W.F. Fumonisin B1 dosimetry in relation to cancer initiation in rat liver. Carcinogenesis. 15:1994;209-214.
15. Griffiths B.B., Rea W.J., Johnson A.R., Ross G. Mitogenic effects of mycotoxins on T4 lymphocytes. Microbios. 86:1996;127-134.
16. Guengerich F.P. Forging the links between metabolism and carcinogenesis. Mutation Research. 488:2001;195-209.
17. Hengstler J.G., Van der Burg B., Steinberg P., Oesch F. Interspecies differences in cancer susceptibility and toxicity. Drug and Metabolism Reviews. 31:1999;917-970.
18. Imaoka S., Ikemoto S., Shimada T., Funae Y. Mutagenic activation of aflatoxin B1 by pulmonary, renal, and hepatic cytochrome P450s from rats. Mutation Research. 269:1992;231-236.
19. International Agency for Research in Carcinogenesis, 1993a. Aflatoxins. Monograph on the Evaluation of Carcinogenic Risks to Humans, Vol. 56, p. 245.
20. International Agency for Research in Carcinogenesis, 1993b. Toxins derived from Fusarium moniliforme: Fumonisins B1 and B2 and fusarin C. Monograph on the Evaluation of Carcinogenic Risks to Humans, Vol. 56, p. 445.
21. dull suppressor cells in spleens of mice intraperitoneally infected with E. multilocularis. Journal of Immunology. 147:1991;1659-1663.
22. Kpodo K., Thrane U., Hald B. Fusaria and fumonisins in maize from Ghana and their co-occurrence with aflatoxins. International Journal of Food Microbiology. 61:2000;147-157.
23. Leslie J.F. Introductory biology of Fusarium moniliforme. Advances in Experimental Medicine and Biology. 392:1996;153-164.
24. Li Y.C., Ledoux D.R., Bermudez A.J., Fritsche K.L., Rottinghaus G.E. Effects of fumonisin B1 on selected immune responses in broiler chicks. Poultry Science. 78:1999;1275-1282.
25. Martinova E.A. Influence of sphingolipids on T lymphocyte activation. Biochemistry (Mosc). 63:1997;102-110.
26. Merrill A.H. Jr., Sullards M.C., Wang E., Voss K.A., Riley R.T. Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. Environmental Health Perspectives. 109:(Suppl. 2):2001;283-289.
27. Midio A.F., Campos R.R., Sabino M. Occurrence of aflatoxins B1, B2, G1 and G2 in cooked food components of whole meals marketed in fast food outlets of the city of Sao Paulo, Brazil. Food Additives and Contaminants. 18:2001;445-448.
28. Moon E.Y., Rhee D.K., Pyo S. Inhibition of various functions in murine peritoneal macrophages by aflatoxin B1 exposure in vivo. International Journal of Immunopharmacology. 21:1999;47-58.
29. Moon E.Y., Rhee D.K., Pyo S. In vitro suppressive effect of aflatoxin B1 on murine peritoneal macrophages functions. Toxicology. 133:1999;171-179.
30. Nepote M.C., Piontelli E., Saubois A. Occurrence of Aspergillus flavus and aflatoxins in corn from Santa Fe, Argentina. Archives of Latinoamerican Nutrition. 47:1997;262-264.
31. Ono E.Y., Ono M.A., Funo F.Y., Medinal A.E., Oliveira T.C., Kawamura O., Ueno Y., Hirooka E.Y. Evaluation of fumonisin-aflatoxin co-occurrence in Brazilian corn hybrids by ELISA. Food Additives and Contaminants. 18:2001;719-729.
32. Pitt J.I. Toxigenic fungi and mycotoxins. British Medical Bulletin. 56:2000;184-192.
33. Quist C.F., Bounous D.I., Kilburn J.V., Nettles V.F., Wyatt R.D. The effect of dietary aflatoxin on wild turkey poults. Journal of Wildlife Diseases. 36:2000;436-444.
34. Raisuddin S., Singh K.P., Zaidi S.I., Paul B.N., Ray P.K. Immunosuppressive effects of aflatoxin in growing rats. Mycopathologia. 124:1993;189-194.
35. Riley R.T., Enongene E., Voss K.A., Norred W.P., Meredith F.I., Sharma R.P., Spitsbergen J., Williams D.E., Carlson D.B., Merrill A.H. Jr. Sphingolipids perturbations as mechanisms for fumonisin carcinogenesis. Environmental Health Perspectives. 109:(Suppl. 2):2001;301-308.
36. Ross P.F., Ledet A.E., Owens D.L., Rice L.G., Nelson H.A., Osweiler G.D., Wilson T.M. Experimental equine leukoencephalomalacia, toxic hepatosis, and encephalopathy caused by corn naturally contaminated with fumonisins. Journal of Veterinary Diagnostic Investigation. 5:1993;69-74.
37. Sabder B., Hoiden I., Andersson U., Moller E., Abrams J.S. Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Journal of Immunology Methods. 166:1993;201-214.
38. Sell S., Xu K.L., Huff W.E., Kabena L.F., Harvery R.B., Dunsford H.A. Aflatoxin exposure produces serum alphafetoprotein elevations and marked oval cell proliferation in young male Pekin ducklings. Pathology. 30:1998;34-39.
39. Shephard G.S., Sydenham E.W., Thiel P.G., Gelderblom W.C.A. Quantitative determination of fumonisins B1 and B2 by high performance liquid chromatography with fluorescence detection. Journal of Liquid Chromatography. 13:1990;2077-2087.
40. Theumer M.G., López A.G., Masih D.T., Chulze S.N., Rubinstein H.R. Immunobiological effects of fumonisin B1 in experimental subchronic mycotoxicoses in rats. Clinical and Diagnostic Laboratory Immunology. 9:2002;149-155.
41. Voss K.A., Plattner R.D., Bacon C.W., Norred W.P. Comparative studies of hepatotoxicity and fumonisin B1 and B2 content of water and chloroform/methanol extracts of Fusarium moniliforme strain MRC 826 culture material. Mycopatologia. 112:1990;81-92.
42. Voss K.A., Riley R.T., Norred W.P., Bacon C.W., Meredith F.I., Howard P.C., Plattner R.D., Collins T.F., Hansen D.K., Porter J.K. An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. Environmental Health Perspectives. 109:(Suppl. 2):2001;259-266.