Development of a high-throughput fluoroimmunoassay for Syk kinase and Syk kinase inhibitors

Analytical Biochemistry

Volumn 315, Issue 2, 2003, Pages 256-261

  Yamamoto, Noriyuki ^a   Hasegawa, Haruki ^a,b   Seki, Hitomi ^a   Ziegelbauer, Karl ^a,c   Yasuda, Takahiro ^a,d  

^a BAYER YAKUHIN LTD   (Japan)

^b UNIVERSITY OF MICHIGAN   (United States)

^c BAYER AG   (Germany)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Asthma; Europium based fluoroimmunoassay; High throughput screening; Syk

Indexed keywords

AMINO ACIDS; CELL CULTURE; CELL MEMBRANES; CHEMICAL ACTIVATION; CHEMICAL DETECTION; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ASTHMA; COATED SUBSTRATES; CONCENTRATION-DEPENDENT; FLUORO IMMUNOASSAYS; HIGH THROUGHPUT SCREENING; KINASE INHIBITORS; PHOSPHORYLATED TYROSINE; TYROSINE RESIDUES;

ENZYME INHIBITION;

ADENOSINE TRIPHOSPHATE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT PROTEIN;

ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; AUTOPHOSPHORYLATION; BACULOVIRUS; CONTROLLED STUDY; DIAGNOSTIC VALUE; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME MECHANISM; FLUOROIMMUNOASSAY; HUMAN; IMMUNOPRECIPITATION; INSECT CELL; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS INFECTION;

INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0037446255     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(03)00026-5     Document Type: Article

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