The inhibition and selectivity of bacterial topoisomerases by BMS-284756 and its analogues

Journal of Antimicrobial Chemotherapy

Volumn 48, Issue 2, 2001, Pages 195-201

  Lawrence, Laura E ^a   Wu, Ping ^a   Fan, Li ^a   Gouveia, Kristine E ^b   Card, Amy ^a   Casperson, Margaret ^a   Denbleyker, Kenneth ^a   Barrett, John F ^a  

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BMS 340278; BMS 340280; BMS 340281; BMS 433366; CIPROFLOXACIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; GARENOXACIN; LEVOFLOXACIN; MOXIFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; ASSAY; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; GENE MUTATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INHIBITION KINETICS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STEREOISOMERISM; STREPTOCOCCUS PNEUMONIAE;

EID: 0034888431     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/48.2.195     Document Type: Article

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