Prion protein gene polymorphisms in a population of Spanish cows

Veterinary Record

Volumn 152, Issue 7, 2003, Pages 212-213

  Naharro, G ^a   Yugueros, J ^a   Temprano, A ^a   del Rio M L ^a   Rodriguez Ferri E F ^a   Luengo, J M ^a  

^a UNIVERSITY OF LEÓN   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DNA; NONAPEPTIDE; PRION PROTEIN;

AGAR GEL ELECTROPHORESIS; AMINO ACID SEQUENCE; ARTICLE; BLOOD SAMPLING; BOVINE SPONGIFORM ENCEPHALOPATHY; CONTROLLED STUDY; COW; DNA EXTRACTION; DNA POLYMORPHISM; GENE AMPLIFICATION; GENETIC VARIABILITY; GENOTYPE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; POPULATION DISTRIBUTION; SPAIN;

BOVINAE;

EID: 0037443135     PISSN: 00424900     EISSN: None     Source Type: Journal    
DOI: 10.1136/vr.152.7.212     Document Type: Article

References (22)

1. ANDERSON, R. M., DONNELLY, C. A., FERGUSON, N. M., WOOLHOUSE, M. E., WATT, C. J., UDY, H. J., MAWHINNEY, S., DUNSTAN, S. P., SOUTHWOOD, T. R., WILESMITH, J. W., RYAN, J. B., HOINVILLE, L. J., HILLERTON, J. E., AUSTIN, A. R. & WELLS, G. A. (1996) Transmission dynamics and epidemiology of BSE in British cattle. Nature 382, 779-788
2. BELT, P. B., MUILEMAN, I. H., SCHREUDER, B. E., BOS-DE RUIJTER, J., GIELKENS, A. L. & SMITS, A. A. (1995) Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie. Journal of General Virology 76, 509-517
3. BORCHELT, D. R., SCOTT, M., TARABOULOS, A., STAHL, N. & PRUSINER, S. B. (1990) Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells. Journal of Cell Biology 110, 743-752
4. BRUCE, M. E., WILL, R. G., IRONSIDE, J. W., MCCONNELL, I., DRUMMOND, D., SUTTIE, A., MCCARDLE, L., CHREE, A., HOPE, J., BIRKETT, C., COUSENS, S., FRASER, H. & BOSTOCK, C. J. (1997) Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 389, 498-501
5. CAUGHEY, B. & RAYMOND, G. J. (1991) The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive. Journal of Biological Chemistry 266, 18217-18223
6. CLOUSCARD, C., BEAUDRY, P., ELSEN, J. M., MILAN, D., DUSSAUCY, M., BOUNNEAU, C., SCHELCHER, F., CHATELAIN, J., LAUNAY, J. M. & LAPLANCHE, J. L. (1995). Different allelic effects of the codons 136 and 171 of the prion protein gene in sheep with natural scrapie. Journal of General Virology 76, 2097-2101
7. COLLINGE, J., SIDLE, K. C., MEADS, J., IRONSIDE, J. & HILL, A. F. (1996) Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. Nature 383, 685-690
8. GASSET, M., BALDWIN, M. A., LLOYD, D. H., GABRIEL, J. M., HOLTZMAN, D. M., COHEN, F., FLETTERICK, R. & PRUSINER, S. B. (1992) Predicted alpha-helical regions of the prion protein when synthesised as peptides form amyloid. Proceedings of the National Academy of Sciences of the United States of America 89, 10940-10944
9. GOLDMANN, W., HUNTER, N., BENSON, G., FOSTER, J. D. & HOPE, J. (1991) Different scrapie-associated fibril proteins (PrP) are encoded by lines of sheep selected for different alleles of the Sip gene. Journal of General Virology 72, 2411-2417
10. HUNTER, N. (1997) PrP genetics in sheep and the implications for scrapie and BSE. Trends in Microbiology 5, 331-334
11. HUNTER, N., CAIRNS, D., FOSTER, J. D., SMITH, G., GOLDMANN, W. & DONNELLY, K. (1997) Is scrapie solely a genetic disease? Nature 386, 137
12. HUNTER, N., FOSTER, J. D., GOLDMANN, W., STEAR, M. J., HOPE, J. & BOSTOCK, C. (1996) Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes. Archives of Virology 141, 809-824
13. HUNTER, N., GOLDMANN, W., SMITH, G. & HOPE, J. (1994) Frequencies of PrP gene variants in healthy cattle and cattle with BSE in Scotland. Veterinary Record 135, 400-403
14. MCKENZIE, D., BARTZ, J., MIRWALD, J., OLANDER, D., MARSH, R. & AIKEN, J. (1998) Reversibility of scrapie inactivation is enhanced by copper. Journal of Biological Chemistry 273, 25545-25547
15. MCKINLEY, M. P., BOLTON, D. C. & PRUSINER, S. B. (1983) A protease-resistant protein is a structural component of the scrapie prion. Cell 35, 57-62
16. MEYER, R. K., MCKINLEY, M. P., BOWMAN, K. A., BRAUNFELD, M. B., BARRY, R. A. & PRUSINER, S. B. (1986) Separation and properties of cellular and scrapie prion proteins. Proceedings of the National Academy of Sciences of the United States of America 83, 2310-2314
17. NEIBERGS, H. L., RYAN, A. M., WOMACK, J. E., SPOONER, R. L. & WILLIAMS, J. L. (1994) Polymorphism analysis of the prion gene in BSE-affected and unaffected cattle. Animal Genetics 25, 313-317
18. QIN, K., YANG, D. S., YANG, Y., CHISHTI, M. A., MENG, L. J., KRETZSCHMAR, H. A., YIP, C. M., FRASER, P. E. & WESTAWAY, D. (2000) Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation. Journal of Biological Chemistry 275, 19121-19131
19. REQUENA, J. R., GROTH, D., LEGNAME, G., STADTMAN, R. R., PRUSINER, S. B. & LEVINE, R. L. (2001) Copper-catalyzed oxidation of the recombinant SHa (29-231) prion protein. Proceedings of the National Academy of Sciences of the United States of America 98, 7170-7175
20. SCHLÄPFER, J., SAITBEKOVA, N., GAILLARD, C. & DOLF, G. (1999) A new allelic variant in the bovine prion protein gene (PRNP) coding region. Animal Genetics 30, 386-387
21. VILES, J. H., COHEN, F. E., PRUSINER, S. B., GOODIN, D. B., WRIGHT, P. E. & DYSON, H. J. (1999) Copper binding to the prion proteins: structural implications of four identical cooperative binding sites. Proceedings of the National Academy of Sciences of the United States of America 96, 2042-2047
22. WILL, R. G., IRONSIDE, J. W., ZEIDLER, M., COUSENS, S. N., ESTIBEIRO, K., ALPEROVITCH, A., POSER, S., POCCHIARI, M., HOFMAN, A. & SMITH, P. G. (1996) A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347, 921-925