Influenza virosomes: Combining optimal presentation of hemagglutinin with immunopotentiating activity

Vaccine

Volumn 21, Issue 9-10, 2003, Pages 925-931

  Huckriede, Anke ^a   Bungener, Laura ^a   Ter Veer, Wouter ^a   Holtrop, Marijke ^a   Daemen, Toos ^a   Palache, Abraham M ^b   Wilschut, Jan ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b Solvay Pharmaceuticals Inc   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HEMAGGLUTININ; IMMUNOSTIMULATING RECONSTITUTED INFLUENZA VIROSOME; INFLUENZA VACCINE; ISCOM; UNCLASSIFIED DRUG; VIROSOME; VIRUS ANTIGEN;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; CELL MATURATION; CELLULAR IMMUNITY; CLINICAL TRIAL; CONFERENCE PAPER; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DRUG DELIVERY SYSTEM; HUMAN; IMMUNOGENICITY; INFLUENZA VACCINATION; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ADJUVANTS, IMMUNOLOGIC; ANTIGENS, VIRAL; CELL DIFFERENTIATION; DENDRITIC CELLS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA VACCINES; MODELS, IMMUNOLOGICAL; VIROSOMES;

EID: 0037435832     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(02)00542-X     Document Type: Conference Paper

References (50)

1. Postma M.J., Bos J.M., van Gennep M., Jager J.C., Baltussen R., Sprenger M.J. Economic evaluation of influenza vaccination. Assessment for The Netherlands. PharmacoEconomics. 16:1999;33-40.
2. Cox N.J., Subbarao K. Influenza. Lancet. 354:1999;1277-1282.
3. Wright PF, Webster RG. Orthomyxoviruses. In: Knipe DM, Howley PM, editors. Fields virology. Philadelphia: Lippincott; 2001. p. 1533-79.
4. Beyer W.E.P., Palache A.M., Osterhaus A.D.M.E. Comparison of serology and reactogenicity between influenza subunit vaccines and whole virus or split vaccines: a review and meta-analysis of the literature. Clin. Drug Invest. 15:1998;1-12.
5. Palache A.M. Influenza vaccines: a reappraisal of their use. Drugs. 54:1997;841-856.
6. Gross P.A., Hermogenes A.W., Sacks H.S., Lau J., Levandowski R.A. The efficacy of influenza vaccine in elderly persons. A meta-analysis and review of the literature. Ann. Intern. Med. 123:1995;518-527.
7. Beyer W.E.P., Palache A.M., de Jong J.C., Osterhaus A.D.M.E. Cold-adapted live influenza vaccine versus inactivated vaccine: systemic vaccine reactions, local and systemic antibody response, and vaccine efficacy. A meta-analysis. Vaccine. 20(9-10):2002;1340-1353.
8. Palache A.M., Beyer W.E.P., Sprenger M.J.W.et al. Antibody response after influenza immunization with various vaccine doses: a double-blind, placebo-controled, multi-centre, dose-response study in elderly nursing-home residents and young volunteers. Vaccine. 11(1):1993;3-9.
9. Baumgarth N. A two-phase model of B-cell activation. Immunol. Rev. 176:2000;171-180.
10. Morein B., Simons K. Subunit vaccines against enveloped viruses: virosomes, micelles and other protein complexes. Vaccine. 3(2):1985;83-93.
11. Bachmann M.F., Zinkernagel R.M. The influence of virus structure on antibody responses and virus serotype formation. Immunol. Today. 17:1996;553-558.
12. Bachmann M.F., Zinkernagel R.M. Neutralizing antiviral B cell responses. Ann. Rev. Immunol. 15:1997;235-270.
13. Bachmann M.F., Hoffmann R.U., Kündig T.M., Bürki K., Hengartner H., Zinkernagel R.M. The influence of antigen organization on B cell responsiveness. Science. 262:1993;1448-1451.
14. Szomolanyi-Tsuda E., Le Q.P., Garcea R.L., Welsh R.M. T-cell-independent immunoglobulin G responses in vivo are elicited by live-virus infection but not by immunization with viral proteins or virus-like particles. J. Virol. 72:1998;6665-6670.
15. Dintzis H.M., Dintzis R.Z., Vogelstein B. Molecular determinants of immunogenicity. Proc. Natl. Acad. Sci. USA. 73:1976;3671-3675.
16. Milich D., Schodel F., Hughes J., Jones J., Peterson D. The hepatitis B virus core and e antigens elicit different Th cell subsets: antigen structure can affect Th cell phenotype. J. Virol. 71:1997;2192-2201.
17. Zinkernagel R.M., Hengartner H. Regulation of the immune response by antigen. Science. 293:2001;251-253.
18. Eldridge JH, Staas JK, Meulbroek JA, Tice TR, Gilley RM. Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies. Infect Immun 59(9):2978-86.
19. St. Clair N., Shenoy B., Jacob L.D., Margolin A.L. Cross-linked protein crystals for vaccine delivery. Proc. Natl. Acad. Sci. USA. 96(17):1999;9469-9474.
20. Ramachandra L., Chu R.S., Askew D.et al. Phagocytic antigen processing and effects of microbial products on antigen processing and T-cell responses. Immunol. Rev. 168:1999;217-239.
21. Nossal GJV. Vaccines. In: Paul WE, editor. Fundamental immunology. Philadelphia: Lippincott-Raven; 1999. p. 1387-425.
22. Rimmelzwaan G.F., Osterhaus A.D.M.E. Influenza vaccines: new developments. Curr. Opin. Pharmacol. 1:2001;491-496.
23. Alving C.R., Wassef N.M. Cytotoxic T lymphocytes induced by liposomal antigens: mechanisms of immunologic presentation. AIDS Res. Human Retrovir. 10(Suppl 2):1994;S91-S94.
24. Tartour E., Ciree A., Haicheur N., Benchetrit F., Fridman W.H. Development of non-live vectors and procedures (liposomes, pseudo-viral particles, toxin, adjuvants, ...) as tools for cancer vaccines. Immunol. Lett. 74:2000;45-50.
25. Nakanishi T., Hayashi A., Kunisawa J.et al. Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway. Eur. J. Immunol. 30:2000;1740-1747.
26. Arkema A., Huckriede A., Schoen P., Wilschut J., Daemen T. Induction of cytotoxic T lymphocyte activity by fusion-active peptide-containing virosomes. Vaccine. 18:2000;1327-1333.
27. Mellman I., Steinman R.M. Dendritic cells: specialized and regulated antigen processing machines. Cell. 106:2001;255-258.
28. Liu Y.J. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell. 106:2001;259-266.
29. Jonuleit H., Schmitt E., Schuler G., Knop J., Enk A.H. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192(9):2000;1213-1222.
30. Dhodapkar M.V., Steinman R.M., Krasovsky J., Munz C., Bhardwaj N. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J. Exp. Med. 193(2):2001;233-238.
31. Cella M., Salio M., Sakakibara Y., Langen H., Julkunen I., Lanzavecchia A. Maturation, activation and protection of dendritic cells induced by double-stranded RNA. J. Exp. Med. 189:1999;821-829.
32. Keitel WA, Piedra PA. Live cold-adapted, reassortant influenza vaccines (USA). In: Nicholson KG, Webster RG, Hay AJ, editors. Textbook of influenza. Oxford: Blackwell Scientific Publications; 1998. p. 373-90.
33. Belshe R.B., Mendelman P.M., Treanor J.et al. The efficacy of live-attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine in children. N. Engl. J. Med. 338:1998;1405-1412.
34. Pfleiderer M., Löwer J., Kurth R. Cold-attenuated live influenza vaccines, a risk-benefit analysis. Vaccine. 20:2002;886-894.
35. Almeida J.D., Brand C.M., Edwards D.C., Heath T.D. Formation of virosomes from influenza subunits and liposomes. Lancet. 2:1975;899-901.
36. Stegmann T., Morselt H.W.M., Booy F., van Breemen J.F.L., Scherphof G., Wilschut J. Functional reconstitution of influenza virus envelopes. EMBO J. 6:1987;2651-2659.
37. Bron R., Ortiz A., Dijkstra J., Stegmann T., Wilschut J. Preparation, properties, and applications of reconstituted influenza virus envelopes (virosomes). Methods Enzymol. 220:1993;313-331.
38. Huckriede A, Bungener L, Daemen T, Wilschut J. Influenza virosomes in vaccine development. Methods Enzymol, in press.
39. Matlin K.S., Reggio H., Helenius A., Simons K. Infectious entry pathway of influenza virus in a canine kidney cell line. J. Cell Biol. 91:1981;601-613.
40. Glück R., Mischler R., Brantschen S., Just M., Althaus B., Cryz S.J. Jr. Immunopotentiating reconstituted influenza-virus virosome vaccine delivery system for immunization against hepatitis A. J. Clin. Invest. 90:1992;2491-2495.
41. Glück R., Mischler R., Finkel B., Que J.U., Scarpa B., Cryz S.J. Jr. Immunogenicity of new virosome influenza vaccine in elderly people. Lancet. 344:1994;160-163.
42. Morein B., Sundquist B., Hoglund S., Dalsgaard K., Osterhaus A. ISCOM, a novel structure for antigenic presentation of membrane proteins from enveloped viruses. Nature. 308:1984;457-460.
43. Ben Ahmeida E.T.S., Gregoriadis G., Potter C.W., Jennings R. Immunopotentiation of local and systemic humoral immune responses by ISCOMs, liposomes and FCA: role in protection against influenza A in mice. Vaccine. 11(13):1993;1302-1309.
44. Babai I., Samira S., Barenholz Y., Zakay-Rones Z., Kedar E. A novel influenza subunit vaccine composed of liposome-encapsulated heamagglutinin/neuraminidase and IL-2 or GM-CSF. I. Vaccine characterization and efficacy studies in mice. Vaccine. 17:1999;1223-1238.
45. Guy B., Pascal N., Françon A.et al. Design, characterization and preclinical efficacy of a cationic lipid adjuvant for influenza split vaccine. Vaccine. 19:2001;1794-1805.
46. Saurwein-Teissl M., Zisterer K., Schmitt T.L., Glück R., Cryz S., Grubeck-Loebenstein B. Whole virus influenza vaccine activates dendritic cells (DC) and stimulates cytokine production by peripheral blood mononuclear cells (PBMC) while subunit vaccines support T cell proliferation. Clin. Exp. Immunol. 114:1998;271-276.
47. Bungener L., Serre K., Bijl L., Leserman L., Wilschut J., Daemen T., Machy P. Virosome-mediated delivery of protein antigens to dendritic cells. Vaccine. 20:2002;2287-2295.
48. Conne P., Gauthey L., Vernet P.et al. Immunogenicity of trivalent subunit versus virosome-formulated influenza vaccines in geriatric patients. Vaccine. 15:1997;1675-1679.
49. Schaad U.B., Buhlmann U., Burger R.et al. Comparison of immunogenicity and safety of a virosome influenza vaccine with those of a subunit influenza vaccine in pediatric patients with cystic fibrosis. Antimicrob Agents Chemother. 44(5):2000;1163-1167.
50. Bron R., Ortiz A., Wilschut J. Cellular cytoplasmic delivery of a polypeptide toxin by reconstituted influenza virus envelopes (virosomes). Biochemistry. 33:1994;9110-9117.