Trypanocidal activity of conformationally restricted pentamidine congeners

Journal of Medicinal Chemistry

Volumn 46, Issue 6, 2003, Pages 1041-1048

  Donkor, Isaac O ^a   Huang, Tien L ^b   Tao, Bin ^b   Rattendi, Donna ^c   Lane, Schennella ^c   Vargas, Marc ^c   Goldberg, Burt ^c   Bacchi, Cyrus ^c  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b XAVIER UNIVERSITY OF LOUISIANA   (United States)

^c PACE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 BIS(4 AMIDINOPHENOXYMETHYLENE)CYCLOPROPANE; ANTITRYPANOSOMAL AGENT; N,N' BIS(4 AMIDINOPHENYL)HOMOPIPERAZINE; N,N' BIS(4 AMIDINOPHENYL)PIPERAZINE; PENTAMIDINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG CONFORMATION; DRUG DNA BINDING; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ANALYSIS; TRYPANOSOMA BRUCEI; TRYPANOSOMA RHODESIENSE;

AMIDINES; ANIMALS; CATIONS; CATTLE; DNA; DRUG RESISTANCE; FEMALE; MICE; MOLECULAR CONFORMATION; PENTAMIDINE; PIPERAZINES; POLY DA-DT; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA BRUCEI RHODESIENSE; TRYPANOSOMIASIS;

EID: 0037435065     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020375q     Document Type: Article

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