Two approaches to peanut allergy

New England Journal of Medicine

Volumn 348, Issue 11, 2003, Pages 1046-1048

  Metzger, Henry ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN E RECEPTOR; PLACEBO;

B LYMPHOCYTE; BASOPHIL; CLINICAL TRIAL; DESENSITIZATION; EDITORIAL; HUMAN; MAST CELL; MONOCYTE; PEANUT ALLERGY; PRIORITY JOURNAL; PROVOCATION TEST;

ANTIBODIES, MONOCLONAL; HUMANS; IMMUNOGLOBULIN E; OINTMENTS; PEANUT HYPERSENSITIVITY; RISK FACTORS;

EID: 0037434887     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMe030007     Document Type: Editorial

References (14)

1. Prausnitz C, Küstner H. Studien über die Ueberempfindlichkeit. Zentralbl Bakteriol 1921;86:160-9.
2. Crater SE, Platts-Mills TA. Searching for the cause of the increase in asthma. Curr Opin Pediatr 1998;10:594-9.
3. Wurzburg BA, Jardetzky TS. Structural insights into the interactions between human IgE and its high affinity receptor FcepsilonRI. Mol Immunol 2002;38:1063-72.
4. Kawakami T, Galli SJ. Regulation of mast-cell and basophil function and survival by IgE. Nat Rev Immunol 2002;2:773-86.
5. Valenta R, Kraft D. From allergen structure to new forms of allergen-specific immunotherapy. Curr Opin Immunol 2002;14:718-27.
6. Hiller R, Laffer S, Harwanegg C, et al. Microarrayed allergen molecules: diagnostic gatekeepers for allergy treatment. FASEB J 2002;16:414-6.
7. Leung DYM, Sampson HA, Yunginger JW, et al. Effect of anti-IgE therapy in patients with peanut allergy. N Engl J Med 2003;348: 986-93.
8. Chang TW. The pharmacological basis of anti-IgE therapy. Nat Biotechnol 2000;18:157-62.
9. Rigby LJ, Trist H, Snider J, et al. Monoclonal antibodies and synthetic peptides define the active site of FcepsilonRI and a potential receptor antagonist. Allergy 2000;55:609-19.
10. MacGlashan DW, Bochner BS, Adelman DC, et al. Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody. J Immunol 1997;158:1438-45.
11. Supajatura V, Ushio H, Nakao A, et al. Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity. J Clin Invest 2002;109:1351-9.
12. H1-mediated autoimmune disorders: lack of support for the hygiene hypothesis. J Allergy Clin Immunol 2003;111:131-5.
13. Hourihane JO. Recent advances in peanut allergy. Curr Opin Allergy Clin Immunol 2002;2:227-31.
14. Lack G, Fox D, Northstone K, Golding J. Factors associated with the development of peanut allergy in childhood. N Engl J Med 2003; 348:977-85.