Cannabinoids inhibit gap junctional intercellular communication and activate erk in a rat liver epithelial cell line

International Journal of Cancer

Volumn 104, Issue 1, 2003, Pages 12-18

  Upham, Brad L ^a,b   Rummel, Alisa M ^a   Carbone, Joseph M ^a   Trosko, James E ^a,b   Ouyang, Yanli ^b,c   Crawford, Robert B ^b,c   Kaminski, Norbert E ^b,c  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Cannabinol; Epigenetic toxicity; Gap junctional intercellular communication; Tetrahydro cannabinol; Tumor promotion

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CANNABINOID; CANNABINOID RECEPTOR; CANNABINOL; DRONABINOL; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; TUMOR MARKER; TUMOR PROMOTER;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL COMMUNICATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; GAP JUNCTION; GENE ACTIVATION; GENOTOXICITY; GROWTH INHIBITION; LEUKOCYTE; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR PROMOTION;

ANIMALS; BORNANES; CANNABINOL; CELL COMMUNICATION; CELL LINE; CYCLIC AMP; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL CELLS; FLAVONOIDS; GAP JUNCTIONS; LIVER; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PIPERIDINES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PYRAZOLES; RATS; RATS, INBRED F344; RECEPTOR, CANNABINOID, CB2; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; RNA, MESSENGER; TETRAHYDROCANNABINOL;

EID: 0037430202     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10899     Document Type: Article

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