Phosphate ester serum albumin affinity tags greatly improve peptide half-life in vivo

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 9, 2003, Pages 1513-1515

  Zobel, Kerry ^a   Koehler, Michael F T ^a   Beresini, Maureen H ^a   Caris, Lisa D ^a   Combs, Daniel ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT PROTEIN; GADOFOSVESET; ORGANOPHOSPHATE; PEPTIDE; SERUM ALBUMIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG HALF LIFE; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLASMA HALF LIFE; PROTEIN TARGETING; RABBIT; REDUCTION;

ORYCTOLAGUS CUNICULUS;

EID: 0037420811     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00209-9     Document Type: Article

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